1. Felix I. Feldchtein

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    1. Mentioned In 30 Articles

    2. Optical coherence angiography for pre-treatment assessment and treatment monitoring following photodynamic therapy: a basal cell carcinoma patient study

      Explore Nature Publishing Group Dermatology
      Optical coherence angiography for pre-treatment assessment and treatment monitoring following photodynamic therapy: a basal cell carcinoma patient study
      Microvascular networks of human basal cell carcinomas (BCC) and surrounding skin were assessed with optical coherence angiography (OCA) in conjunction with photodynamic therapy (PDT). OCA images were collected and analyzed in 31 lesions pre-treatment, and immediately/24hours/312 months post-treatment. Pre-treatment OCA enabled differentiation between prevalent subtypes of BCC (nodular and superficial) and nodular-with-necrotic-core BCC subtypes with a diagnostic accuracy of 78%; this can facilitate more accurate biopsy reducing sampling ...
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      Mentions: University of Toronto Felix I. Feldchtein I. Alex Vitkin

    3. In-vivo longitudinal imaging of microvascular changes in irradiated oral mucosa of radiotherapy cancer patients using optical coherence tomography

      Explore Nature Publishing Group
      In-vivo longitudinal imaging of microvascular changes in irradiated oral mucosa of radiotherapy cancer patients using optical coherence tomography
      Mucositis is the limiting toxicity of radio(chemo)therapy of head and neck cancer. Diagnostics, prophylaxis and correction of this condition demand new accurate and objective approaches. Here we report on an in vivo longitudinal monitoring of the oral mucosa dynamics in 25 patients during the course of radiotherapy of oropharyngeal and nasopharyngeal cancer using multifunctional optical coherence tomography (OCT). A spectral domain OCT system with a specially-designed oral imaging ...
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      Mentions: University of Toronto Felix I. Feldchtein I. Alex Vitkin

    4. Pixel classification method in optical coherence tomography for tumor segmentation and its complementary usage with OCT microangiography

      Explore Wiley Online Library Oncology
      Pixel classification method in optical coherence tomography for tumor segmentation and its complementary usage with OCT microangiography
      A novel machine-learning method to distinguish between tumor and normal tissue in optical coherence tomography (OCT) has been developed. Pre-clinical murine ear model implanted with mouse colon carcinoma CT-26 was used. Structural-image-based feature sets were defined for each pixel and machine learning classifiers were trained using ground truth OCT images manually segmented by comparison with histology. The accuracy of the OCT tumour segmentation method was then quantified by comparing with ...
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      Mentions: University of Toronto Felix I. Feldchtein I. Alex Vitkin

    5. Quantitative evaluation of atherosclerotic plaques using cross-polarization optical coherence tomography, nonlinear, and atomic force microscopy

      Explore SPIE | Journal Cardiology
      Quantitative evaluation of atherosclerotic plaques using cross-polarization optical coherence tomography, nonlinear, and atomic force microscopy
      A combination of approaches to the image analysis in cross-polarization optical coherence tomography (CP OCT) and high-resolution imaging by nonlinear microscopy and atomic force microscopy (AFM) at the different stages of atherosclerotic plaque development is studied. This combination allowed us to qualitatively and quantitatively assess the disorganization of collagen in the atherosclerotic arterial tissue (reduction and increase of CP backscatter), at the fiber (change of the geometric distribution of fibers ...
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      Mentions: Felix I. Feldchtein Nizhny Novgorod State Medical Academy Grigory V. Gelikonov

    6. Characterization of atherosclerotic plaques by cross-polarization optical coherence tomography

      Explore Conference Proceedings Cardiology
      Characterization of atherosclerotic plaques by cross-polarization optical coherence tomography
      We combined cross-polarization optical coherence tomography (CP OCT) and non-linear microscopy based on second harmonic generation (SHG) and two-photon-excited fluorescence (2PEF) to assess collagen and elastin fibers in the development of the atherosclerotic plaque (AP). The study shows potential of CP OCT for the assessment of collagen and elastin fibers condition in atherosclerotic arteries. Specifically, the additional information afforded by CP OCT, related to birefringence and cross-scattering properties of arterial ...
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      Mentions: Ontario Cancer Institute University of Toronto Felix I. Feldchtein

    7. Multi-modal optical imaging characterization of atherosclerotic plaques

      Explore Wiley Online Library Cardiology
      Multi-modal optical imaging characterization of atherosclerotic plaques
      We combined cross-polarization optical coherence tomography (CP OCT) and non-linear microscopy based on second harmonic generation (SHG) and two-photon-excited fluorescence (2PEF) to assess collagen and elastin fibers and other vascular structures in the development of atherosclerosis, including identification of vulnerable plaques, which remains an important clinical problem and imaging application. CP OCT's ability to visualize tissue birefringence and cross-scattering adds new information about the microstructure and composition of the ...
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      Mentions: Ontario Cancer Institute University of Toronto Felix I. Feldchtein

    8. Quantitative Evaluation of the Polarization Characteristics of Coronary Arteries Atherosclerotic Plaques at Different Development Stages

      Explore Журнал СТМ
      Quantitative Evaluation of the Polarization Characteristics of Coronary Arteries Atherosclerotic Plaques at Different Development Stages
      The aim of the investigation was to develop an approach to quantitative evaluation of polarization properties (birefringence and cross-scattering) basing on cross-polarization OCT images (CP OCT) in order to characterize the development stages of atherosclerotic plaques and to reveal unstable ones. Materials and Methods. We report on quantitative analysis of CP OCT images of the seven development stages of atherosclerotic plaques ex vivo . Integral depolarization factor (IDF) and effective birefringence ...
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      Mentions: Felix I. Feldchtein Nizhny Novgorod State Medical Academy Institute of Applied Physics

    9. Imalux Ceases Operation

      Explore Optical Coherence Tomography News Other Business News
      Imalux Ceases Operation
      Imalux Corporation has announced that it has ceased operations due to various challenges to become a profitable on-going business. Imalux Corporation was one of the earliest OCT startup companies and received its first seed funding in 2000. Imalux opened operations in Cleveland Ohio with a strong technology connection to the Institute of Applied Physics in Russia. With the visionary leadership of Paul Amazeen and Felix Feldchtein Imalux developed the Niris ...
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      Mentions: Paul Amazeen Imalux Felix I. Feldchtein

    10. Evaluation of oral mucosa collagen condition with cross-polarization optical coherence tomography

      Explore Wiley Online Library Dentistry
      Evaluation of oral mucosa collagen condition with cross-polarization optical coherence tomography
      The goal of the research was analysis of the effect of collagen condition in formation of cross-polarized CP OCT images. We used of the CP OCT technique for studying collagen condition on an example of oral mucosa. Special histologic picrosirius red (PSR) staining of cheek mucosa specimens was used with subsequent assessing of the result of collagen staining in polarized light. High correlation (r = 0.692, p = 0.0001) between ...
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      Mentions: Felix I. Feldchtein Nizhny Novgorod State Medical Academy Natalia D. Gladkova

    11. Optical coherence tomography device and method having improved boundary control and distortion correction

      Explore uspto.gov Patents
      Optical coherence tomography device and method having improved boundary control and distortion correction
      Variants of an interferometric device are developed for examining internal structures of objects by means of optical coherence tomography, which allow for controlling a boundary location of the observation range. The device also allows for correcting a distortion of the tomographic image of the object under study, caused by lateral scanning, due to aberrations of the optical path length for the low-coherence optical radiation directed towards the object. Embodiments of ...
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      Mentions: Imalux Felix I. Feldchtein Grigory V. Gelikonov

    12. Common path systems and methods for frequency domain and time domain optical coherence tomography using non-specular reference reflection and a delivering device for optical radiation with a partially optically transparent non-specular reference reflector

      Explore uspto.gov Patents , Probes
      Common path systems and methods for frequency domain and time domain optical coherence tomography using non-specular reference reflection and a delivering device for optical radiation with a partially optically transparent non-specular reference reflector
      Provided are common path frequency domain and time domain OCT systems and methods that use non-specular reference reflection for obtaining internal depth profiles and depth resolved images of samples. Further provided is a delivering device for optical radiation, preferably implemented as an optical fiber probe with a partially optically transparent non-specular reflector placed in the vicinity of an associated sample. High frequency fringes are substantially reduced and a stable power ...
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      Mentions: Imalux Felix I. Feldchtein

    13. Polarization-sensitive common path optical coherence reflectometry/tomography device

      Explore uspto.gov Patents
      Polarization-sensitive common path optical coherence reflectometry/tomography device
      Polarization sensitive common path OCT/OCR devices are presented. Optical radiation from a source is converted into two cross-polarized replicas propagating therethrough with a predetermined optical path length difference. The two cross-polarized replicas are then delivered to an associated sample by a delivering device, which is, preferably, an optical fiber probe. A combination optical radiation is produced in at least one secondary interferometer by combining a corresponding portion of an ...
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      Mentions: Imalux Felix I. Feldchtein Grigory V. Gelikonov

    14. Feature Of The Week 9/27/09: Collective Dynamics of Swimming Bacteria: OCT Studies

      Explore Optical Coherence Tomography News Other Non-Medical
      Feature Of The Week 9/27/09: Collective Dynamics of Swimming Bacteria: OCT Studies
      Feature Of The Week 9/27/09: Physical mechanisms governing large-scale organization of self-propelled biological microparticles, such as motor proteins, swimming bacteria, and other motile cells, attract significant attention among physicists and biologists. Scientists from Argonne National Laboratory, Imalux, and Cambridge University, discovered that commonly found bacteria such as Bacillus Subtilis are in fact highly efficient mixers for the liquid they live in. Thanks to original non-invasive optical coherence tomography ...
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      Mentions: Imalux Princeton University Felix I. Feldchtein
    17. 1-15 of 30 1 2 »
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  4. About Felix I. Feldchtein

    Felix I. Feldchtein

    Felix I. Feldchtein is one of the creators of the first optical coherence tomography device in the former Soviet Union and one of the original founders of Imalux (initially Optical Coherence Technologies Inc.). He has contributed to over 60 scientific publications and multiple patents. Dr. Feldchtein is the laureate of 1999 Russian State Prize in Science and Technology for work in optical coherence tomography.  Dr. Feldchtein is also with Institute of Applied Physics of the Russian Academy of Sciences.

  5. Related Topics

    1. Optical fiber lateral scanner for a miniature optical fiber probe
      22 articles also mentioned Imalux
    2. Optical coherence tomography apparatus, optical fiber lateral scanner and a method for studying biological tissues in vivo
      14 articles also mentioned Natalia D. Gladkova
    3. Method for studying a sample and optical interferometer for doing the same
      12 articles also mentioned Valentin M. Gelikonov
    4. Application of optical coherence tomography in the diagnosis of mucositis in patients with head and neck cancer during a course of radio(chemo)therapy
      9 articles also mentioned Nizhny Novgorod State Medical Academy

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    1. SBIR programs are often judged mainly by academically minded panels focusing on academic merit. As a result, scientifically innovative proposals with very questionable commercial potential are winning over innovative technologies which are ready for the market but have already lost academic attractiveness.
      In Optical Coherence Tomography Used $500M of Federally Funded Research Over The Past Decade: How was it Used, What was Accomplished, and What’s to Come?