1. Fangyi Chen

    0 Comments Leave a Comment

    1-9 of 9
    1. Mentioned In 9 Articles

    2. Reflective type objective based spectral-domain phase-sensitive optical coherence tomography for high-sensitive structural and functional imaging of cochlear microstructures through intact bone of an excised guinea pig cochlea

      Reflective type objective based spectral-domain phase-sensitive optical coherence tomography for high-sensitive structural and functional imaging of cochlear microstructures through intact bone of an excised guinea pig cochlea
      ...r microstructures through intact bone of an excised guinea pig cochlea Hrebesh M. Subhash ; Ruikang K. Wang ; Fangyi Chen ; Alfred L. Nuttall; Reflective type objective based spectral-domain phase-sensitive optical coher...
      Read Full Article
    3. Feature Of The Week 3/17/13: Using Optical Coherence Tomography to Study Mechanisms of Hearing

      Feature Of The Week 3/17/13: Using Optical Coherence Tomography to Study Mechanisms of Hearing

      The Oregon Hearing Research Centre (OHRC) at the Oregon Health and Science University (OHSU), Portland, Oregon is one of the strongest hearing research groups in the world, and one of the early adopters of optical coherence tomography technology in the field of hearing research. Researchers at OHRC have developed a couple of novel OCT based imaging technologies for functional imaging of middle and inner ear. This includes high-speed OCT system for in vivo imaging of microstructural morphology and micvascular perfusion within the cochlea [1,2], phase-sensitive time-domain and Fourier domain OCT for studying cochlear micromechanics [3,4] and middle ear ...

      Read Full Article
    4. Measurement of in vivo basal-turn vibrations of the organ of Corti using phase-sensitive Fourier domain optical coherence tomography

      Measurement of in vivo basal-turn vibrations of the organ of Corti using phase-sensitive Fourier domain optical coherence tomography
      ...hase-sensitive Fourier domain optical coherence tomography Sripriya Ramamoorthy ; Yuan Zhang ; Tracy Petrie ; Fangyi Chen ; Hrebesh M. Subhash ; Niloy Choudhury ; Ruikang Wang ; Steven L. Jacques ; Alfred L. Nuttall; Mea...
      Read Full Article
    5. Depth-resolved dual-beamlet vibrometry based on Fourier domain low coherence interferometry

      Depth-resolved dual-beamlet vibrometry based on Fourier domain low coherence interferometry

      We present an optical vibrometer based on delay-encoded, dual-beamlet phase-sensitive Fourier domain interferometric system to provide depth-resolved subnanometer scale vibration information from scattering biological specimens. System characterization, calibration, and preliminary vibrometry with biological specimens were performed. The proposed system has the potential to provide both amplitude and direction of vibration of tissue microstructures on a single two-dimensional plane.

      Read Full Article
    6. Feature Of The Week 5/27/11: Researchers Utilize Optical Coherence Tomography to Perform in vivo Investigation into the Process of Hearing

      Feature Of The Week 5/27/11: Researchers Utilize Optical Coherence Tomography to Perform in vivo Investigation into the Process of Hearing
      ... by the active process presumed to underlie normal hearing. For more information see recent Article. Courtesy Fangyi Chen and Alfred Nuttall from the Oregon Health & Science University. A multidisciplinary research group...
      Read Full Article
    7. Absolute measurement of subnanometer scale vibration of cochlear partition of an excised guinea pig cochlea using spectral-domain phase-sensitive optical coherence tomography

      Absolute measurement of subnanometer scale vibration of cochlear partition of an excised guinea pig cochlea using spectral-domain phase-sensitive optical coherence tomography

      Direct measurement of absolute vibration parameters from different locations within the mammalian organ of Corti is crucial for understanding the hearing mechanics such as how sound propagates through the cochlea and how sound stimulates the vibration of various structures of the cochlea, namely, basilar membrane (BM), recticular lamina, outer hair cells and tectorial membrane (TM). In this study we demonstrate the feasibility a modified phase-sensitive spectral domain optical coherence tomography system to provide subnanometer scale vibration information from multiple angles within the imaging beam. The system has the potential to provide depth resolved absolute vibration measurement of tissue microstructures from ...

      Read Full Article
    8. Imaging Organ of Corti Vibration Using Fourier-Domain OCT

      Imaging Organ of Corti Vibration Using Fourier-Domain OCT

      Measuring the sound stimulated vibration from various structures in the organ of Corti is important in understanding how the small vibrations are amplified and detected. In this study we examine the feasibility of using phase-sensitive Fourier domain optical coherence tomography (PSFD-OCT) to measure vibration of the cellular structures of the organ of Corti. PSFD-OCT is a low coherence interferrometry system where the interferrogram is detected as a function of wavelength. The phase of the Fourier transformation of the detected spectra contains path deference (between the sample arm and the reference arm) information of the interferometer. In PSFD-OCT this phase is ...

      Read Full Article
    9. A differentially amplified motion in the ear for near-threshold sound detection

      A differentially amplified motion in the ear for near-threshold sound detection

      The ear is a remarkably sensitive pressure fluctuation detector. In guinea pigs, behavioral measurements indicate a minimum detectable sound pressure of ~20 μPa at 16 kHz. Such faint sounds produce 0.1-nm basilar membrane displacements, a distance smaller than conformational transitions in ion channels. It seems that noise within the auditory system would swamp such tiny motions, making weak sounds imperceptible. Here we propose a new mechanism contributing to a resolution of this problem and validate it through direct measurement. We hypothesized that vibration at the apical side of hair cells is enhanced compared with that at the commonly measured ...

      Read Full Article
    10. 1-9 of 9
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources, Velocimetry
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. About Fangyi Chen

    Fangyi Chen

    Fangyi Chen is a research engineer at Oregon Hearing Research Center at Oregon Health and Science University.