1. Evelyn Regar

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    1. Mentioned In 151 Articles

    2. Frequency domain multiplexing for speckle reduction in optical coherence tomography

      Frequency domain multiplexing for speckle reduction in optical coherence tomography
      Quantitative analysis of optical coherence tomography data can be strongly hampered by speckle. Here, we introduce a new method to reduce speckle, which leverages from Fourier-domain configurations and operates on individual axial scans. By subdividing the digitized spectrum into a number of distinct narrower windows, each with a different center frequency, several independent speckle patterns result. These can be averaged to yield a lower-resolution image with strongly reduced speckle. The ...
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    3. Online Three-Dimensional Rendering of Optical Coherence Tomography Images for the Assessment of Bifurcation Intervention

      Online Three-Dimensional Rendering of Optical Coherence Tomography Images for the Assessment of Bifurcation Intervention
      Three-dimensional optical coherence tomography rendering has been suggested as a method providing additive information for the assessment of the result of percutaneous coronary intervention. However, rendering of such models is very time-consuming and cannot be performed online during the intervention. We present a case in which a new method for 3-dimensional rendering of optical coherence tomography images helped visualize the stentvessel wall interaction, providing useful information that discouraged further intervention.
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    4. Carina shift as a mechanism for side-branch compromise following main vessel intervention: Insights from three-dimensional optical coherence tomography

      Carina shift as a mechanism for side-branch compromise following main vessel intervention: Insights from three-dimensional optical coherence tomography
      ... Processing, Department of Radiology, Leiden University Medical Center, Leiden, Netherlands Corresponding to: Evelyn Regar, MD, PhD. Department of Cardiology, Thoraxcenter, Erasmus MC,‘s Gravendijkwal 230, 3015CE Rotterd...
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    5. Plaque sealing and passivation with a mechanical self-expanding low outward force nitinol VShield device for the treatment of intravascular ultrasound and optical coherence tomography-derived thin cap fibroatheromas (TCFAS) in native coronary arteries

      Plaque sealing and passivation with a mechanical self-expanding low outward force nitinol VShield device for the treatment of intravascular ultrasound and optical coherence tomography-derived thin cap fibroatheromas (TCFAS) in native coronary arteries
      Aims: The aim of the pilot SECRITT trial was to evaluate the safety and feasibility of sealing the high risk IVUS and optical coherence tomography-derived thin cap fibroatheroma (TCFA), with a dedicated nitinol self-expanding vShield device. Methods and results: After screening with angiography, fractional flow reserve (FFR), intravascular ultrasound virtual histology (IVUS-VH) and optical coherence tomography (OCT), 23 patients met enrolment criteria (presence of non-obstructive VH-derived TCFA lesion with thin ...
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    6. Invasive imaging of the coronary atherosclerotic plaque

      Invasive imaging of the coronary atherosclerotic plaque
      Coronary atherosclerosis has a high prevalence and is known as the leading cause of death worldwide. Clinically, coronary atherosclerosis is routinely evaluated by coronary angiography, which provides a luminogram of the coronary artery and allows for recognizing lumen narrowing. However, angiography does not allow for the direct assessment of the disease process within the coronary vessel wall. Today, a number of catheter-based imaging methods can overcome this shortcoming and provide ...
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    7. Expert review document part 2: methodology, terminology and clinical applications of optical coherence tomography for the assessment of interventional procedures

      Expert review document part 2: methodology, terminology and clinical applications of optical coherence tomography for the assessment of interventional procedures
      Introduction This document is complementary to an Expert Review Document on Optical Coherence Tomography (OCT) for the study of coronary arteries and atherosclerosis.1 The goal of this companion manuscript is to provide a practical guide framework for the appropriate use and reporting of the novel frequency domain (FD) OCT imaging to guide interventional procedures, with a particular interest on the comparison with intravascular ultrasound (IVUS).1–4 Technique for ...
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    8. Interstudy reproducibility of the second generation, Fourier domain optical coherence tomography in patients with coronary artery disease and comparison with intravascular ultrasound: a study applying automated contour detection

      Interstudy reproducibility of the second generation, Fourier domain optical coherence tomography in patients with coronary artery disease and comparison with intravascular ultrasound: a study applying automated contour detection
      Recently, Fourier domain OCT (FD-OCT) has been introduced for clinical use. This approach allows in vivo, high resolution (15 micron) imaging with very fast data acquisition, however, it requires brief flushing of the lumen during imaging. The reproducibility of such fast data acquisition under intracoronary flush application is poorly understood. To assess the inter-study variability of FD-OCT and to compare lumen morphometry to the established invasive imaging method, IVUS. 18 ...
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    9. OCT in Coronary Bifurcations (Book Chapter)

      OCT in Coronary Bifurcations (Book Chapter)
      The geometric and anatomical complexity of bifurcations makes its systematic scientific approach very challenging. Optical coherence tomography (OCT) is able to depict accurately the plaque distribution around the bifurcation, to provide valuable information to tailor the procedure in each specific case, and to assess the result after stenting. Some guidelines are proposed for the systematic study of bifurcations with OCT, assessing the apposition, tissue coverage, the presence of overlap or ...
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    10. Differences in Neointimal Thickness Between the Adluminal and the Abluminal Sides of Malapposed and Side-Branch Struts in a Polylactide Bioresorbable Scaffold: Evidence In Vivo About the Abluminal Healing Process

      Differences in Neointimal Thickness Between the Adluminal and the Abluminal Sides of Malapposed and Side-Branch Struts in a Polylactide Bioresorbable Scaffold: Evidence In Vivo About the Abluminal Healing Process
      ...m the strut to the vessel wall or bidirectional. Juan Luis Gutiérrez-Chico, MD, PhD*, Frank Gijsen, MSc, PhD, Evelyn Regar, MD, PhD*, Jolanda Wentzel, MSc, PhD, Bernard de Bruyne, MD, PhD, Leif Thuesen, MD, John Ormiston...
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    11. Residual atherothrombotic material after stenting in acute myocardial infarction — An optical coherence tomographic evaluation

      Residual atherothrombotic material after stenting in acute myocardial infarction — An optical coherence tomographic evaluation
      Background Thrombus aspiration (TA) in patients with ST segment elevation myocardial infarction (STEMI) results in a better myocardial perfusion. Optical coherence tomography (OCT) after stenting in STEMI, however, often reveals residual atherothrombotic material. We assessed the feasibility of quantification of residual atherothrombotic burden and its relation to indices of myocardial perfusion. The effect of TA on residual in-stent atherothrombotic burden (ATB) is explored. Methods and results Forty patients with STEMI ...
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    12. Consensus Standards for Acquisition, Measurement, and Reporting of Intravascular Optical Coherence Tomography Studies: A Report From the International Working Group for Intravascular Optical Coherence Tomography Standardization and Validation

      Consensus Standards for Acquisition, Measurement, and Reporting of Intravascular Optical Coherence Tomography Studies: A Report From the International Working Group for Intravascular Optical Coherence Tomography Standardization and Validation
      ...clinicians who use IVOCT and analyze IVOCT data Guillermo J. Tearney, MD, PhD, Writing Committee Co-Chair*,*, Evelyn Regar, MD, PhD, Writing Committee Co-Chair, Takashi Akasaka, MD, Writing Committee Co-Chair, Tom Adriae...
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    13. Response to Letter Regarding Article, “Delayed Coverage in Malapposed and Side-Branch Struts With Respect to Well-Apposed Struts in Drug-Eluting Stents: In Vivo Assessment With Optical Coherence Tomography”

      Response to Letter Regarding Article, “Delayed Coverage in Malapposed and Side-Branch Struts With Respect to Well-Apposed Struts in Drug-Eluting Stents: In Vivo Assessment With Optical Coherence Tomography”
      ...Stents: In Vivo Assessment With Optical Coherence Tomography” 1. Juan Luis Gutiérrez-Chico, MD, PhD, FESC; 2. Evelyn Regar, MD, PhD, FESC; 3. Takayuki Okamura, MD, PhD; 4. Joanna Wykrzykowska, MD; 5. Patrick W. Serruys, ...
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    14. Wavelength multiplexing for FD-OCT speckle averaging

      Wavelength multiplexing for FD-OCT speckle averaging
      Quantitative analysis of OCT data can be strongly hampered by speckle. We propose a new method to reduce speckle, operating on a single Fourier-domain optical coherence tomography (FD-OCT) A-line. The full acquired spectrum is used for image generation, exhibiting fully developed speckle. By subdividing the same acquired spectrum in a number of distinct narrower windows, each with a different center frequency, several independent speckles can be generated. These can be ...
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    15. Vascular Tissue Reaction to Acute Malapposition in Human Coronary Arteries: Sequential Assessment With Optical Coherence Tomography

      Vascular Tissue Reaction to Acute Malapposition in Human Coronary Arteries: Sequential Assessment With Optical Coherence Tomography
      Background—The vascular tissue reaction to acute incomplete stent apposition (ISA) is not well known. The aim of this study was to characterize the vascular response to acute ISA in vivo and to look for predictors of incomplete healing. Methods and Results—Optical coherence tomography studies of 66 stents of different designs, implanted in 43 patients enrolled in 3 randomized trials, were analyzed sequentially after implantation and at 6 to ...
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    16. 61-75 of 151 « 1 2 3 4 5 6 7 8 9 10 »
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  2. About Evelyn Regar

    Evelyn Regar

    Evelyn Regar is a interventional cardiologist at the ThoraxCenter, Erasmus Medical Center in the Netherlands.  Dr. Regar did her preclinical studies at the University of Regensburg, Germany, for two years, before training at the Technical University of Munich. From there, she trained in internal medicine and cardiology at the University Hospital, also in Munich. Since 1999, she works as an interventional cardiologist at the Thoraxcenter and has the post of clinical head of the catheter laboratory.

  3. Quotes

    1. The ILUMIEN system provides me and my colleagues with an easy-to-use, flexible solution that combines OCT and FFR technology on one system... Having these two cutting edge technologies together is a welcome advancement for therapy guidance, allowing me to choose the right tools for each patient situation.
      In St. Jude Medical Announces European Approval of First and Only Combined FFR and OCT System