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    1. Mentioned In 47 Articles

    2. Acousto-optical coherence tomography with a digital holographic detection scheme

      Acousto-optical coherence tomography with a digital holographic detection scheme
      Acousto-optical coherence tomography (AOCT) consists in using random phase jumps on ultrasound and light to achieve a millimeter resolution when imaging thick scattering media. We combined this technique with heterodyne off-axis digital holography. Two-dimensional images of absorbing objects embedded in scattering phantoms are obtained with a good signal-to-noise ratio. We study the impact of the phase modulation characteristics on the amplitude of the acousto-optic signal and on the contrast and ...
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    3. Guiding glaucoma laser surgery using Fourier-domain optical coherence tomography at 1.3 μm

      Guiding glaucoma laser surgery using Fourier-domain optical coherence tomography at 1.3 μm
      Glaucoma is a disease of the optic nerve that is usually associated with an increased internal pressure of the eye and can lead to a decreased vision and eventually blindness. It is the second leading cause of blindness worldwide with more than 80 million people affected and approximately 6 million blind. The standard clinical treatment for glaucoma, after unsuccessful administration of eyedrops and other treatments, is performing incisional surgery. However ...
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    4. Feature Of The Week 11/27/11: Langevin Institute and LLTech Investigate In Vivo Cellular Full-Field OCT Imaging with a Rigid Endoscopic Probe

      Feature Of The Week 11/27/11: Langevin Institute and LLTech Investigate In Vivo Cellular Full-Field OCT Imaging with a Rigid Endoscopic Probe
      ...ero-digestive and gastrointestinal tracts.For more information see recent Article. Courtesy Anne Latrive from Langevin Institute, ESPCI and LLTech.    References1. Dubois and A.C. Boccara, “Full-field optical coheren...
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    5. Single myelin fiber imaging in living rodents without labeling by deep optical coherence microscopy

      Single myelin fiber imaging in living rodents without labeling by deep optical coherence microscopy
      Myelin sheath disruption is responsible for multiple neuropathies in the central and peripheral nervous system. Myelin imaging has thus become an important diagnosis tool. However, in vivo imaging has been limited to either low-resolution techniques unable to resolve individual fibers or to low-penetration imaging of single fibers, which cannot provide quantitative information about large volumes of tissue, as required for diagnostic purposes. Here, we perform myelin imaging without labeling and ...
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    6. OPTICAL COHERENCE TOMOGRAPHY/BIOIMAGING: One decade and $500M: The impact of federal funding on OCT - Part 2

      OPTICAL COHERENCE TOMOGRAPHY/BIOIMAGING: One decade and $500M: The impact of federal funding on OCT - Part 2
      EDITOR'S NOTE: This article is the follow-up article to "One decade and $500M: The impact of federal funding on OCT—Part 1," which appears in the September/October 2011 issue of BioOptics World. Over the past decade, governments around the world have invested hundreds of millions of dollars in research and development involving optical coherence tomography (OCT). Part Two of this two-part article explores the return on that investment ...
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    7. In vivo and in situ cellular imaging full-field optical coherence tomography with a rigid endoscopic probe

      In vivo and in situ cellular imaging full-field optical coherence tomography with a rigid endoscopic probe
      Full-field OCT has proved to be a powerful high-resolution cellular imaging tool for biological tissues. However the standard bulk full-field OCT setup does not match the size requirements for most in situ and in vivo imaging applications. We adapted its principle into a rigid needle-like probe using two coupled interferometers and incoherent illumination: an external processing interferometer is used for in-depth scanning, while a distal common-path interferometer at the tip ...
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    8. You are Invited to the LLTECH Open Lab Session in North Brunswick, NJ.

      You are Invited to the LLTECH Open Lab Session in North Brunswick, NJ.
      LLTech Press Release.  You are Invited to the  LLTECH OPEN LAB SESSION. Bring Your Samples. Sept 22nd 2011, North Brunswick, NJ. LLTech's Light-Coherent Tomography (Light-CTTM) provides a non-sacrificial digital cellular imaging solution for the Hospital and the Life-Sciences Pathology Lab. Using light instead of ultrasounds, the Light-CT can scan tissues and display high resolution (<1micron) 2D and 3D fully digital images.       Meet Pr Claude Boccara, LLTECH's CSO       Pr ...
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    9. Dr Claude Boccara and LLTECH’s Digital Pathology Technology Receive Prestigious NIH Bench-to-Bedside Pioneer Award

      Dr Claude Boccara and LLTECH’s Digital Pathology Technology Receive Prestigious NIH Bench-to-Bedside Pioneer Award
      LLTech Press Release: At the conclusion of the first day of the 7th NIH Inter-Institute Workshop on Optical Diagnostic and Biophotonics Methods from Bench to Bedside, Professor Boccara has received the prestigious NIH Bench to Bedside Pioneer Award from the hands of Dr Amir Gandjbakhche, Program Chair and Chief of Section of the NIH Laboratory of Integrative and Medical Biophysics.   The NIH Inter-Institute Optical Diagnostic and Biophotonics Methods Workshop is ...
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    10. Optical Coherence Tomography Used $500M of Federally Funded Research Over The Past Decade: How was it Used, What was Accomplished, and What’s to Come?

      Optical Coherence Tomography Used $500M of Federally Funded Research Over The Past Decade: How was it Used, What was Accomplished, and What’s to Come?
      The field of optical coherence tomography (OCT) has blossomed dramatically since some of the first work by various researchers around the world in the late 1980s and early 1990s. Since then there have been dozens of companies created, hundreds of research groups working on OCT, thousands of research articles published, millions of patients scanned with OCT, hundreds of millions of venture capital and corporate R&D dollars invested, hundreds of ...
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    11. Theoretical study of acousto-optical coherence tomography using random phase jumps on ultrasound and light

      Theoretical study of acousto-optical coherence tomography using random phase jumps on ultrasound and light
      Acousto-optical coherence tomography (AOCT) is a variant of acousto-optic imaging (also called ultrasonic modulation imaging) that makes it possible to get the z resolution with acoustic and optic continuous wave beams. We describe here theoretically the AOCT effect, and we show that the acousto-optic “tagged photons” remain coherent if they are generated within a specific z region of the sample. We quantify the z selectivity for both the “tagged photon ...
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    12. LLTech launches the ultra high resolution - micron level - 3D Light-CT scanner for research

      LLTech launches the ultra high resolution - micron level - 3D Light-CT scanner for research
      LLTech, innovative company in the area of optical imaging launches the Light-CT research scanner.   The Light-CT scanner is an optical imaging system, using the properties of white light and optics generating DICOM, 3D, ultra high-resolution images of tissue microstructure, without introducing artifacts. It offers an ultra high resolution: 1.5 µm lateral (X,Y) and 1 µm axial (Z)       This versatile system offers new research opportunities for biologists, pharmaceutical companies ...
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    13. Brain refractive index measured in vivo with high-NA defocus-corrected full-field OCT and consequences for two-photon microscopy

      Brain refractive index measured in vivo with high-NA defocus-corrected full-field OCT and consequences for two-photon microscopy
      Two-photon laser scanning microscopy (2PLSM) is an important tool for in vivo tissue imaging with sub-cellular resolution, but the penetration depth of current systems is potentially limited by sample-induced optical aberrations. To quantify these, we measured the refractive index n' in the somatosensory cortex of 7 rats in vivo using defocus optimization in full-field optical coherence tomography (ff-OCT). We found n' to be independent of imaging depth or rat age ...
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    14. LLTech brings optical biopsies to operating theaters: Coherence tomography technique allows surgeons to see biopsy results in 3D and almost real-time.

      LLTech brings optical biopsies to operating theaters: Coherence tomography technique allows surgeons to see biopsy results in 3D and almost real-time.
      Optical biopsy techniques have been a focus of interest in biophotonics for many years. The use of spectroscopy to provide the kind of diagnosis that must normally wait for histology or cytology is an attractive proposition, potentially saving time, money and patient discomfort. Now LLTech, a venture-stage company based in Paris, has developed a coherence tomography process called Light-CT that could present surgical staff with 3D visualizations of tissue samples ...
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    15. Acousto-optical coherence tomography using random phase jumps on ultrasound and light

      Acousto-optical coherence tomography using random phase jumps on ultrasound and light
      Imaging objects embedded within highly scattering media by coupling light and ultrasounds (US) is a challenging approach. In deed, US enable direct access to the spatial localization, though resolution can be poor along their axis (cm). Up to now, several configurations have been studied, giving a millimetric axial resolution by applying to the US a microsecond pulse regime, as is the case with conventional echography. We introduce a new approach ...
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    16. Defocus test and defocus correction in full-field optical coherence tomography

      Defocus test and defocus correction in full-field optical coherence tomography
      We report experimental evidence and correction of defocus in full-field optical coherence tomography of biological samples owing to mismatch of the refractive index of biological tissues and water. Via a metric based on the image quality, we demonstrate that we are able to compensate this ... [Opt. Lett. 34, 1576-1578 (2009)]
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    17. Full-field OCT approaches clinical application

      Full-field OCT approaches clinical application
      Newly developed Cell OCT, an approach to full-field optical coherence tomography, has enabled researchers to image breast-cancer tissue with histology-like results. Full-field OCT is an en face (transverse), broadband interferometric approach to optical coherence tomography (OCT) that’s been in use for life-science research for more than a decade.1–3 The technique offers many advantages, including fast tissue imaging at the cellular level, which is why at ESPCI (Ecole ...
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    18. Full-field optical coherence tomography (oct) and early alterations in chloroplast morphology

      Full-field optical coherence tomography (oct) and early alterations in chloroplast morphology
      A. C. Boccara, R. De Paepe, A. Dubois et al. After our first demonstration of the early alteration of the chloroplast morphology with the use of both Confocal Microscopy and Optical Coherence Tomography (OCT) and the discussion of the biological mechanisms, we develop here the optical part of this work and underline the merits of full field OC ... [Proc. SPIE Int. Soc. Opt. Eng. 6755, 67550E (2007)] published Tue Sep ...
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    19. 31-47 of 47 « 1 2 3
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  2. About ESPCI ParisTech

    ESPCI ParisTech

    ESPCI ParisTech is a major institution of higher education an internationally renowned research center, and a fertile ground of innovation for industry.  Founded by the City of Paris in 1882, for over a century the School has attracted leading scientific innovators like Nobel Prize laureates Pierre and Marie Curie, Paul Langevin, Frédéric Joliot-Curie, Pierre-Gilles de Gennes, and Georges Charpak, who continue to contribute to the institution’s international reputation.  The School’s culture of excellence remains as vibrant as ever. Fully 60% of graduates go on to complete a thesis and earn their PhD. The School’s teaching faculty and researchers are building tomorrow’s knowledge base, publishing an article a day in top international scientific journals ; inventing the industry of the future, filing for a patent every single week.  A model of excellence and an illustration of the "French exception", ESPCI ParisTech is a founding member of ParisTech, the Paris Institute of Science and Technology.  Also see Langevin Institute (L’institut Langevin).