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    1. Mentioned In 52 Articles

    2. Fast subsurface fingerprint imaging with full-field optical coherence tomography system equipped with a silicon camera

      Fast subsurface fingerprint imaging with full-field optical coherence tomography system equipped with a silicon camera
      Images recorded below the surface of a finger can have more details and be of higher quality than conventional surface fingerprint images. This is particularly true when the quality of the surface fingerprints is compromised by, for example, moisture or surface damage. However, there is an unmet need for a cost effective fingerprint sensor that could record high-quality images at sufficient depth below the surface and in short-enough time. To ...
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    3. Full-Field Optical Coherence Tomography as a Diagnosis Tool: Recent Progress with Multimodal Imaging

      Full-Field Optical Coherence Tomography as a Diagnosis Tool: Recent Progress with Multimodal Imaging
      Full-field optical coherence tomography (FF-OCT) is a variant of OCT that is able to register 2D en face views of scattering samples at a given depth. Thanks to its superior resolution, it can quickly reveal information similar to histology without the need to physically section the sample. Sensitivity and specificity levels of diagnosis performed with FF-OCT are 80% to 95% of the equivalent histological diagnosis performances and could therefore benefit ...
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    4. Extracting relevant information for cancer diagnosis from dynamic full field OCT through image processing and learning

      Extracting relevant information for cancer diagnosis from dynamic full field OCT through image processing and learning
      For a large number of cancer surgeries, the lack of reliable intraoperative diagnosis leads to reoperations or bad outcomes for the patients. To deliver better diagnosis, we developed Dynamic Full Field OCT (D-FFOCT) as a complement to FFOCT. FFOCT already presents interesting results for cancer diagnosis e.g. Mohs surgery and reaching 96% accuracy on prostate cancer. D-FFOCT accesses the dynamic processes of metabolism and gives new tools to diagnose ...
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    5. Retinal imaging with adaptive optics full-field OCT

      Retinal imaging with adaptive optics full-field OCT
      Adaptive optics full-filed OCT (FFOCT) with a transmissive liquid crystal spatial light modulator (LCSLM) as wavefront corrector is used without strict plane conjugation for low order aberrations corrections. We validated experimentally that FFOCT resolution is independent of aberrations and only reduce the signal level. A signal based sensorless algorithm was thus applied for wavefront distortion compensation. Image quality improvements by the wavefront sensorless control of the LCSLM were evaluated on ...
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    6. Dynamic multimodal full-field optical coherence tomography and fluorescence structured illumination microscopy

      Dynamic multimodal full-field optical coherence tomography and fluorescence structured illumination microscopy
      We report on the development of a configuration of a multimodal full-field optical coherence tomography (FF-OCT) and fluorescence microscope. Our system can simultaneously acquire FF-OCT and structured illumination microscopy images. Dynamic parallel evolution of tissue microstructures and biochemical environments can be visualized. We use high numerical aperture objectives to optimize the combination of the two modalities. We imaged the propagation of mechanical waves initiated by calcium waves in a heart ...
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    7. En face coherence microscopy [Invited]

      En face coherence microscopy [Invited]
      En face coherence microscopy or flying spot or full field optical coherence tomography or microscopy (FF-OCT/FF-OCM) belongs to the OCT family because the sectioning ability is mostly linked to the source coherence length. In this article we will focus our attention on the advantages and the drawbacks of the following approaches: en face versus B scan tomography in terms of resolution, coherent versus incoherent illumination and influence of aberrations ...
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    8. Diffuse shear wave imaging: toward passive elastography using low-frame rate spectral-domain optical coherence tomography

      Diffuse shear wave imaging: toward passive elastography using low-frame rate spectral-domain optical coherence tomography
      Optical coherence tomography (OCT) can map the stiffness of biological tissue by imaging mechanical perturbations (shear waves) propagating in the tissue. Most shear wave elastography (SWE) techniques rely on active shear sources to generate controlled displacements that are tracked at ultrafast imaging rates. Here, we propose a noise-correlation approach to retrieve stiffness information from the imaging of diffuse displacement fields using low-frame rate spectral-domain OCT. We demonstrated the method on ...
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    9. Intracellular dynamics measurements with full field optical coherence tomography suggest hindering effect of actomyosin contractility on organelle transport

      Intracellular dynamics measurements with full field optical coherence tomography suggest hindering effect of actomyosin contractility on organelle transport
      Intracellular motion can be quantitatively monitored in tissues using coherence-gated microscopic techniques. With full-field optical coherence tomography (FFOCT), the use of high numerical aperture microscope objectives provides a high resolution mapping of intracellular dynamics that are probed with subwavelength sensitivity. In the upper temporal bandwidth that we have used (1-6 Hz) the main contribution to the dynamic signal arises from the overall dynamical, optically heterogeneous cytoplasm. We propose a method ...
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    10. Adaptive optics full-field optical coherence tomography

      Adaptive optics full-field optical coherence tomography
      We describe a simple and compact full-field optical coherence tomography (FFOCT) setup coupled to a transmissive liquid crystal spatial light modulator (LCSLM) to induce or correct aberrations. To reduce the system complexity, strict pupil conjugation was abandoned because low-order aberrations are often dominant. We experimentally confirmed a recent theoretical and experimental demonstration that the image resolution was almost insensitive to aberrations that mostly induce a reduction of the signal level ...
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    11. Full-field spatially incoherent illumination interferometry: a spatial resolution almost insensitive to aberrations

      Full-field spatially incoherent illumination interferometry: a spatial resolution almost insensitive to aberrations
      We show that with spatially incoherent illumination, the point spread function (PSF) width/spatial resolution of an imaging interferometer like that used in full-field optical coherence tomography (OCT) is almost insensitive to aberrations. In these systems, aberrations mostly induce a reduction of the signal level that leads to a loss of the signal-to-noise ratio without broadening the system PSF. This is demonstrated by comparison with traditional scanning OCT and wide-field ...
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    12. Appearance of the Retina With Full-Field Optical Coherence Tomography

      Appearance of the Retina With Full-Field Optical Coherence Tomography
      Purpose : To interpret full-field optical coherence tomography (FFOCT) images of ex vivo retina. Methods : Flatmounted retinas of human, primate, pig, sheep, rat, and mouse were imaged using FFOCT. To identify retinal ganglion and amacrine cells, fixed samples immunolabeled against Tuj1 and Brn3a or live samples labeled in vitro with green fluorescent protein (GFP) were analyzed by combining FFOCT, fluorescence confocal microscopy (FCM), and fluorescence-FFOCT. To investigate postmortem tissue changes, time ...
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    13. Dynamic full field optical coherence tomography: subcellular metabolic contrast revealed in tissues by interferometric signals temporal analysis

      Dynamic full field optical coherence tomography: subcellular metabolic contrast revealed in tissues by interferometric signals temporal analysis
      We developed a new endogenous approach to reveal subcellular metabolic contrast in fresh ex vivo tissues taking advantage of the time dependence of the full field optical coherence tomography interferometric signals. This method reveals signals linked with local activity of the endogenous scattering elements which can reveal cells where other OCT-based techniques fail or need exogenous contrast agents. We benefit from the micrometric transverse resolution of full field OCT to ...
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    14. High-resolution handheld rigid endomicroscope based on full-field optical coherence tomography

      High-resolution handheld rigid endomicroscope based on full-field optical coherence tomography
      Full-field optical coherence tomography (FF-OCT) is a powerful tool for nondestructive assessment of biological tissue, i.e., for the structural examination of tissue in depth at a cellular resolution. Mostly known as a microscopy device for ex vivo analysis, FF-OCT has also been adapted to endoscopy setups since it shows good potential for in situ cancer diagnosis and biopsy guidance. Nevertheless, all the attempts to perform endoscopic FF-OCT imaging did ...
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    15. Dynamic full field optical coherence tomography: subcellular metabolic contrast revealed in tissues by temporal analysis of interferometric signals

      Dynamic full field optical coherence tomography: subcellular metabolic contrast revealed in tissues by temporal analysis of interferometric signals
      We developed a new endogenous approach to reveal subcellular metabolic contrast in fresh ex vivo tissues taking advantage of the time dependence of the full field optical coherence tomography interferometric signals. This method reveals signals linked with local activity of the endogenous scattering elements which can reveal cells where other imaging techniques fail or need exogenous contrast agents. We benefit from the micrometric transverse resolution of full field OCT to ...
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    16. 1-15 of 52 1 2 3 4 »
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  2. About ESPCI ParisTech

    ESPCI ParisTech

    ESPCI ParisTech is a major institution of higher education an internationally renowned research center, and a fertile ground of innovation for industry.  Founded by the City of Paris in 1882, for over a century the School has attracted leading scientific innovators like Nobel Prize laureates Pierre and Marie Curie, Paul Langevin, Frédéric Joliot-Curie, Pierre-Gilles de Gennes, and Georges Charpak, who continue to contribute to the institution’s international reputation.  The School’s culture of excellence remains as vibrant as ever. Fully 60% of graduates go on to complete a thesis and earn their PhD. The School’s teaching faculty and researchers are building tomorrow’s knowledge base, publishing an article a day in top international scientific journals ; inventing the industry of the future, filing for a patent every single week.  A model of excellence and an illustration of the "French exception", ESPCI ParisTech is a founding member of ParisTech, the Paris Institute of Science and Technology.  Also see Langevin Institute (L’institut Langevin).