1. Erich Götzinger

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    1. Mentioned In 67 Articles

    2. Polarisation-sensitive optical coherence tomography for material

      Polarisation-sensitive optical coherence tomography for material
      Optical Coherence Tomography (OCT) is an emerging technology for high-resolution non-contact imaging of semi-transparent structures. Originally developed for medical diagnostics, we extend the OCT-technique to problems posed in material testing and characterisation. Layer thickness and refractive indices as well as internal structures of polymer parts have been determined within this study. An extension of OCT, namely polarisation-sensitive OCT (PS-OCT) has been used to identify regions of increased anisotropy within injection-moulded ...
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    3. Spectral degree of polarization uniformity for polarization-sensitive OCT

      Spectral degree of polarization uniformity for polarization-sensitive OCT
      Depolarization of light can be measured by polarization-sensitive optical coherence tomography (PS-OCT) and has been used to improve tissue discrimination as well as segmentation of pigmented structures. Most approaches to depolarization assessment for PS-OCT such as the degree of polarization uniformity (DOPU) rely on measuring the uniformity of polarization states using spatial evaluation kernels. In this article, we present a different approach which exploits the spectral dimension. We introduce the ...
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    4. Polarisation-sensitive OCT is useful for evaluating retinal pigment epithelial lesions in patients with neovascular AMD

      Polarisation-sensitive OCT is useful for evaluating retinal pigment epithelial lesions in patients with neovascular AMD
      Background/aims To examine the reproducibility of lesion dimensions of the retinal pigment epithelium (RPE) in neovascular age-related macular degeneration (AMD) with polarisation-sensitive optical coherence tomography (PS-OCT), specifically imaging the RPE. Methods Twenty-six patients (28 eyes) with neovascular AMD were included in this study, and examined by a PS-OCT prototype. Each patient was scanned five times at a 1-day visit. The PS-OCT B-scan located closest to the macular centre presenting ...
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    5. Peripapillary rat sclera investigated in vivo with polarization sensitive optical coherence tomography

      Peripapillary rat sclera investigated in vivo with polarization sensitive optical coherence tomography
      Purpose: To demonstrate polarization sensitive (PS) optical coherence tomography (OCT) for non-invasive, volumetric, and quantitative imaging of the birefringent properties of the peripapillary rat sclera. To compare the findings in PS-OCT images to state-of-the-art histomorphometric analysis of the same tissues. Methods: A high-speed PS-OCT prototype operating at 840 nm was modified for imaging the rat eye. Densely sampled PS-OCT raster scans covering an area of ~1.5 mm 1.5 ...
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    6. Imaging Retinal Pigment Epithelial Proliferation Secondary to PASCAL Photocoagulation In Vivo by Polarization-sensitive Optical Coherence Tomography

      Imaging Retinal Pigment Epithelial Proliferation Secondary to PASCAL Photocoagulation In Vivo by Polarization-sensitive Optical Coherence Tomography
      ...ns + Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria , * Erich Götzinger Affiliations + Center for Medical Physics and Biomedical Engineering, Medical University of Vi...
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    7. Retinal polarization-sensitive optical coherence tomography at 1060 nm with 350 kHz A-scan rate using an Fourier domain mode locked laser

      Retinal polarization-sensitive optical coherence tomography at 1060 nm with 350 kHz A-scan rate using an Fourier domain mode locked laser
      We present a novel, high-speed, polarization-sensitive, optical coherence tomography set-up for retinal imaging operating at a central wavelength of 1060 nm which was tested for in vivo imaging in healthy human volunteers. We use the system in combination with a Fourier domain mode locked laser with active spectral shaping which enables the use of forward and backward sweep in order to double the imaging speed without a buffering stage. With ...
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    8. Measuring Retinal Nerve Fiber Layer Birefringence, Retardation, and Thickness Using Wide-Field, High-Speed Polarization Sensitive Spectral Domain OCT

      Measuring Retinal Nerve Fiber Layer Birefringence, Retardation, and Thickness Using Wide-Field, High-Speed Polarization Sensitive Spectral Domain OCT
      ...ide-Field, High-Speed Polarization Sensitive Spectral Domain OCT 1. Stefan Zotter^1, 2. Michael Pircher^1, 3. Erich Götzinger^1, 4. Teresa Torzicky^1, 5. Hirofumi Yoshida^2, 6. Futoshi Hirose^2, 7. Stephan Holzer^3, 8. J...
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    9. Lesion Size Detection in Geographic Atrophy by Polarization-sensitive Optical Coherence Tomography and Correlation to Conventional Imaging Techniques

      Lesion Size Detection in Geographic Atrophy by Polarization-sensitive Optical Coherence Tomography and Correlation to Conventional Imaging Techniques
      Purpose: To investigate the reproducibility of automated lesion size detection in patients with geographic atrophy (GA) using polarization-sensitive spectral domain-OCT (PS-OCT) and to compare findings with scanning laser ophthalmoscopy (SLO), fundus autofluorescence (FAF), and intensity based SD-OCT. Methods: 29 eyes of 22 patients with GA were examined by PS-OCT, selectively identifying the retinal pigment epithelium (RPE). A novel segmentation algorithm was applied, automatically detecting and quantifying areas of RPE atrophy ...
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    10. High-speed polarization sensitive optical coherence tomography scan engine based on Fourier domain mode locked laser

      High-speed polarization sensitive optical coherence tomography scan engine based on Fourier domain mode locked laser
      We report on a new swept source polarization sensitive optical coherence tomography scan engine that is based on polarization maintaining (PM) fiber technology. The light source is a Fourier domain mode locked laser with a PM cavity that operates in the 1300 nm wavelength regime. It is equipped with a PM buffer stage that doubles the fundamental sweep frequency of 54.5 kHz. The fiberization allows coupling of the scan ...
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    11. Large-field high-speed polarization sensitive spectral domain OCT and its applications in ophthalmology

      Large-field high-speed polarization sensitive spectral domain OCT and its applications in ophthalmology
      We present a novel spectral domain polarization sensitive OCT system (PS-OCT) that operates at an A-scan rate of 70 kHz and supports scan angles of up to 40° × 40°. The high-speed imaging allows the acquisition of up to 1024 × 250 A-scans per 3D scan, which, together with the large field of view, considerably increases the informative value of the images. To demonstrate the excellent performance of the new PS-OCT system ...
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    12. Polarization sensitive optical coherence tomography of melanin provides intrinsic contrast based on depolarization

      Polarization sensitive optical coherence tomography of melanin provides intrinsic contrast based on depolarization
      Polarization sensitive optical coherence tomography (PS-OCT) is a functional extension of OCT. In addition to imaging based on tissue reflectivity, PS-OCT also enables depth-resolved mapping of sample polarization properties such as phase-retardation, birefringent axis orientation, Stokes vectors, and degree of polarization uniformity (DOPU). In this study, PS-OCT was used to investigate the polarization properties of melanin. In-vitro measurements in samples with varying melanin concentrations revealed polarization scrambling, i.e. depolarization ...
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    13. High-speed polarization-sensitive OCT at 1060 nm using a Fourier domain mode-locked swept source

      High-speed polarization-sensitive OCT at 1060 nm using a Fourier domain mode-locked swept source
      Optical coherence tomography (OCT) in the 1060nm range is interesting for in vivo imaging of the human posterior eye segment (retina, choroid, sclera), as it permits a long penetration depth. Complementary to structural images, polarization-sensitive OCT (PS-OCT) images visualize birefringent, polarization-maintaining or depolarizing areas within the sample. This information can be used to distinguish retinal layers and structures with different polarization properties. High imaging speed is crucial for imaging ocular ...
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    14. Feature Of The Week 4/29/12: Medical University of Vienna Demonstrates Automated Measurement of Choroidal Thickness in the Human Eye by PS-OCT

      Feature Of The Week 4/29/12: Medical University of Vienna Demonstrates Automated Measurement of Choroidal Thickness in the Human Eye by PS-OCT
      Researchers at the Medical University of Vienna have a long history of outstanding contributions to the field of Optical Coherence Tomography dating back 25 years.  This week work by Dr. Hitzenberger, one of the pioneers of the field, and his colleagues is featured demonstrating automated measurement of choroidal thickness in the human eye by polarization sensitive optical coherence tomography. Below is a summary of their work.Imaging of retinal layers ...
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    15. High-Speed Retinal Imaging with Polarization-Sensitive OCT at 1040 nm

      High-Speed Retinal Imaging with Polarization-Sensitive OCT at 1040 nm
      Purpose. To demonstrate the ability of a new high-speed polarization-sensitive optical coherence tomography (PS-OCT) system for retinal imaging at 1040 nm. Methods. A new polarization-sensitive swept source OCT system in the 1 [mu]m wavelength range is used to image the retina of healthy volunteers. The instrument is operated at an A-scan rate of 100 kHz which is about three times faster than previously reported PS-OCT instruments in this wavelength ...
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    16. Automated measurement of choroidal thickness in the human eye by polarization sensitive optical coherence tomography

      Automated measurement of choroidal thickness in the human eye by polarization sensitive optical coherence tomography
      We present a new method to automatically segment the thickness of the choroid in the human eye by polarization sensitive optical coherence tomography (PS-OCT). A swept source PS-OCT instrument operating at a center wavelength of 1040 nm is used. The segmentation method is based entirely on intrinsic, tissue specific polarization contrast mechanisms. In a first step, the anterior boundary of the choroid, the retinal pigment epithelium, is segmented based on ...
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  2. About Erich Götzinger

    Erich Götzinger

    Erich Götzinger was born on April 26, 1973 in Vienna Austria. He studied physics at the University of Vienna. After graduating he started his PhD work in the field of OCT at the Medical University of Vienna. He obtained his PhD in 2007. Ever since he is working as a postdoc at the Center for Medical Physics and Biomedical Engineering. His main research interest is polarization sensitive optical coherence tomography.