Wavenumber linear spectrometers are provided including an input configured to receive electromagnetic radiation from an external source; collimating optics configured to collimate the received electromagnetic radiation; a dispersive assembly including first and second diffractive gratings, wherein the first diffraction grating is configured in a first dispersive stage to receive the collimated electromagnetic radiation and wherein the dispersive assembly includes at least two dispersive stages configured to disperse the collimated input; and an imaging lens assembly configured to image the electromagnetic radiation dispersed by the at least two dispersive stages onto a linear detection array such that the variation in frequency ...
Optical coherence tomography (OCT) imaging systems having adaptable lens systems and related methods and computer program products
OCT imaging systems are provided for imaging a spherical-type eye including a source having an associated source arm path and a reference arm having an associated reference arm path coupled to the source path. The reference arm path has an associated reference arm path length. A sample is also provided having an associated sample arm path coupled to the source arm and reference arm paths. A lens having a focal power optimized for a diameter of the spherical-type eye is provided along with a reference arm path length adjustment module coupled to the reference arm. The reference arm path length ...
Methods, systems and computer program products for diagnosing conditions using unique codes generated from a multidimensional image of a sample
Methods of providing a diagnosis using a digital code associated with an image are provided including collecting a multidimensional image, the multidimensional image having at least two dimensions; extracting a two dimensional subset of the multidimensional image; reducing the multidimensional image to a first code that is unique to the multidimensional image based on the extracted two dimensional image; comparing the first unique code associated with the subject to a library of reference codes, each of the reference codes in the library of reference codes being indicative of a class of objects; determining if the subject associated with the first ...
Some embodiments of the present inventive concept provide optical coherence tomography (OCT) systems for integration with a microscope. The OCT system includes a sample arm coupled to the imaging path of a microscope. The sample arm includes an input beam zoom assembly including at least two movable lenses configured to provide shape control for an OCT signal beam; a scan assembly including at least one scanning mirror and configured for telecentric scanning of the OCT signal beam; and a beam expander configured to set the OCT signal beam diameter incident on the microscope objective. The shape control includes separable controls ...
Optical coherence tomography systems for imaging a whole eye are provided including a sample arm including focal optics that are configured to rapidly switch between at least two scanning modes in less than about 1.0 second.
Methods, systems and computer program products for collapsing volume data to lower dimensional representations thereof using histogram projection
Methods of collapsing volume data to a lower dimensional representation of the volume data are provided. The methods include collapsing volume data to a lower dimensional representation of the volume data using histogram projection. Related systems and computer program products are also provided.
Bioptigen Unveils the Envisu IntraSurgical OCT System for Real-time Imaging During Ophthalmic Surgery
Optical coherence tomography (OCT) imaging systems for imaging an eye are provided including a source having an associated source arm path and a reference arm having an associated reference arm path coupled to the source path, the reference arm path having an associated reference arm path length. A sample having an associated sample arm path coupled to the source arm and reference arm paths is provided. A reference arm path length adjustment module is coupled to the reference arm. The reference arm path length adjustment module is configured to automatically adjust the reference arm path length such that the reference ...
Methods, systems and computer program products for managing frequency domain optical coherence tomography (FDOCT) image resolution. A spectrum used to acquire an image of a subject is calibrated and default dispersion correction parameters are set. Default dispersion management parameters associated with a region of the image of the subject are also set. The image of the subject is acquires after setting the default dispersion correction parameters and the default dispersion management parameters. A quality of the acquired image is compared to a quality metric for the acquired image. The dispersion correction parameters are adjusted if the quality of the acquired ...
Systems for extended depth frequency domain optical coherence tomography (FDOCT) and related methods
Systems for extended depth frequency domain optical coherence tomography are provided including a detection system configured to sample spectral elements at substantially equal frequency intervals, wherein a spectral width associated with the sampled spectral elements is not greater than one-half of the frequency interval. Related methods are also provided herein.
About Eric L. Buckland
Eric L. Buckland, Director, President and Chief Executive Officer at Bioptigen has lead technology development, strategic planning, and commercial operations at major global optics companies since 1985. Dr. Buckland was a key executive in Corning Incorporated's Photonics Technologies Division from 1999-2003, and was instrumental in the development of a new division formed to commercialize optical switching technologies for the all-optical network. Dr. Buckland earned his B.S summa cum laude and M.S in physics from North Carolina State University. He earned a Ph.D. in optics from the University of Rochester. He has been awarded 6 patents and has written more than 30 publications and conference presentations.
This advance brings surgeons one step closer to realizing the full value of intraoperative OCT...This is the first OCT system offering fully independent focus and zoom control for optimizing images from the cornea to the retina.In Bioptigen Unveils the Envisu IntraSurgical OCT System for Real-time Imaging During Ophthalmic Surgery
This advance brings surgeons one step closer to realizing the full value of intraoperative OCTIn Bioptigen Unveils the Envisu IntraSurgical OCT System for Real-time Imaging During Ophthalmic Surgery
This latest innovation from Bioptigen enables faster alignment, targeted explorations, and brilliant visualizations, while simultaneously viewing both OCT and color fundus images in real time...We expect this capability will be impactful not only for mouse and rat research, but also for handheld, dual-modality imaging of larger animals including cats, dogs, rabbits, and non-human primates," Buckland added. Bioptigen has begun producing and shipping the new multimodality systems from the company's North Carolina operations center, and will showcase the product at ARVO 2014 in Orlando, May 4-8.In Bioptigen Introduces Image-Guided SDOCT Technology to Advance Preclinical Eye Research
Single pixel slices are possible across the whole 3D image, allowing uniform sampling of data along a warped contour that ‘cuts’ through the center of features as small as a single capillary bed...This is a game‐changer as it allows dynamic exploration of flattened data, another important step towards true optical histology via SD‐OCT.In Bioptigen Introduces Dynamic 3D Tissue Flattening Software for Envisu SD-OCT Systems (See Video)
The importance of the ES100 attachment is that it provides a stabilized mounting solution for OCT in the operating room that minimizes disruptions to surgical procedures, while offering all of the flexibility and imaging performance of the Envisu C2300...The addition of a stable, microscope-mounted option enables exquisite OCT imaging of both anterior and posterior structures in the operating room when handheld imaging is not desired.In Bioptigen introduces operating microscope mount for FDA-cleared Envisu ophthalmic imaging system.
The importance of the ES100 attachment is that it provides a stabilized mounting solution for OCT in the operating room that minimizes disruptions to surgical procedures, while offering all of the flexibility and imaging performance of the Envisu C2300In Bioptigen introduces operating microscope mount for FDA-cleared Envisu ophthalmic imaging system.
The progression to 1 um extreme resolution imaging is an exciting advancement for our Envisu R-Class research product line...The importance of this innovation is that it offers researchers true cellular-level in vivo optical histology. This Extreme High Resolution (XHR) capability is unlocked only by the combination of Bioptigen’s patented spectrometer and signal processing technologies with the NKT Photonics SuperK supercontinuum source.In Bioptigen introduces 1 µm resolution SD-OCT imaging system in collaboration with NKT Photonics supercontinuum white light laser source at ARVO conference in Seattle
The progression to 1 µm extreme resolution imaging is an exciting advancement for our Envisu R-Class research product lineIn Bioptigen introduces 1 µm resolution SD-OCT imaging system in collaboration with NKT Photonics supercontinuum white light laser source at ARVO conference in Seattle
This year has been positively monumental for Bioptigen. “Now that we’ve been cleared to market Envisu practically worldwide, we’re seeing increased demand from clinicians and researchers who appreciate the convenience and flexibility our hand-held scanner provides for patients who can’t be imaged using traditional, tabletop devices.In Bioptigen Expands Headquarters Within Research Triangle Park, NC
Our devices are generally indicated for patients who are not well suited to imaging with traditional, tabletop devices...Bioptigen’s Envisu ophthalmic imaging devices provide a unique degree of flexibility that benefits clinicians and the patients they care for. It’s exciting to be able to market our C-series devices in the United States and support efforts by health-care providers to deliver appropriate medical interventions, especially for the underserved pediatric patient population.In Bioptigen Receives FDA Clearance to Market Envisu Imaging Systems in the USA