1. Erasmus University

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    1. Mentioned In 293 Articles

    2. Tissue characterization with depth-resolved attenuation coefficient and backscatter term in intravascular optical coherence tomography images

      Tissue characterization with depth-resolved attenuation coefficient and backscatter term in intravascular optical coherence tomography images
      An important application of intravascular optical coherence tomography (IVOCT) for atherosclerotic tissue analysis is using it to estimate attenuation and backscatter coefficients. This work aims at exploring the potential of the attenuation coefficient, a proposed backscatter term, and image intensities in distinguishing different atherosclerotic tissue types with a robust implementation of depth-resolved (DR) approach. Therefore, the DR model is introduced to estimate the attenuation coefficient and further extended to estimate ...
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    3. Serial 5-Year Evaluation of Side Branches Jailed by Bioresorbable Vascular Scaffolds Using 3-Dimensional Optical Coherence Tomography

      Serial 5-Year Evaluation of Side Branches Jailed by Bioresorbable Vascular Scaffolds Using 3-Dimensional Optical Coherence Tomography
      Background The long-term fate of Absorb bioresorbable vascular scaffold (Abbott Vascular, Santa Clara, CA) struts jailing side branch ostia has not been clarified. We therefore evaluate serially (post-procedure and at 6 months, 1, 2, 3, and 5 years) the appearance and fate of jailed Absorb bioresorbable vascular scaffold struts. Methods and Results We performed 3-dimensional optical coherence tomographic analysis of the ABSORB Cohort B trial (A Clinical Evaluation of the ...
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    4. Thermo-elastic optical coherence tomography

      Thermo-elastic optical coherence tomography
      The absorption of nanosecond laser pulses induces rapid thermo-elastic deformation in tissue. A sub-micrometer scale displacement occurs within a few microseconds after the pulse arrival. In this Letter, we investigate the laser-induced thermo-elastic deformation using a 1.5 MHz phase-sensitive optical coherence tomography (OCT) system. A displacement image can be reconstructed, which enables a new modality of phase-sensitive OCT, called thermo-elastic OCT. An analysis of the results shows that the ...
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    5. Report of an ESC-EAPCI Task Force on the evaluation and use of bioresorbable scaffolds for percutaneous coronary intervention: executive summary

      Report of an ESC-EAPCI Task Force on the evaluation and use of bioresorbable scaffolds for percutaneous coronary intervention: executive summary
      BRS require careful lesion assessment, to determine the need and extent of lesion preparation, as well as to select the appropriate size and length of the device. The use of pre-and post-procedural intracoronary imaging (Intravascular ultrasound, optical coherence tomography), as well as online quantitative coronary angiography, is encouraged to optimize device implantation. The use of BRS in heavily calcified vessels is strongly discouraged. Bioresorbable scaffolds should be avoided in stenoses ...
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    6. Hemodynamic analysis of a novel bioresorbable scaffold in porcine coronary artery model

      Hemodynamic analysis of a novel bioresorbable scaffold in porcine coronary artery model
      Background The shear stress distribution assessment can provide useful insights for the hemodynamic performance of the implanted stent/scaffold. Our aim was to investigate the effect of a novel bioresorbable scaffold, Mirage on local hemodynamics in animal models. Method The main epicardial coronary arteries of 7 healthy mini-pigs were implanted with 11 Mirage Microfiber sirolimus-eluting Bioresorbable Scaffolds (MMSES). Optical coherence tomography (OCT) was performed post scaffold implantation and the obtained ...
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    7. Intravascular imaging for characterization of coronary atherosclerosis

      Intravascular imaging for characterization of coronary atherosclerosis
      This short review surveys recent developments in coronary intravascular imaging technologies. We present an outline of the applications of intravascular imaging for guidance of percutaneous coronary interventions and imaging of atherosclerosis, along with emerging clinical evidence for use. Imaging of tissue composition is important for understanding the relation between the presence of a lesion and clinical sequelae. We describe the recent innovations to enable imaging of unstable atherosclerotic plaques, focusing ...
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    8. Non-Newtonian pulsatile shear stress assessment: a method to differentiate bioresorbable scaffold platforms

      Non-Newtonian pulsatile shear stress assessment: a method to differentiate bioresorbable scaffold platforms
      In-vitro and in-sili co studies have shown that the implantation of coronary stent or scaffold induces changes in local haemodynamic microenvironment. Coronary angiography and optical coherence tomography (OCT) data were used to perform three-dimensional reconstruction of the right coronary of two healthy mini pigs after implantation of a 3.018mm Absorb BVS with strut thickness of 157 m (Abbott Vascular, USA) and 3.014mm ArterioSorb with strut thickness of 95 ...
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    9. A new technique for lipid core plaque detection by optical coherence tomography for prevention of peri-procedural myocardial infarction: A case report

      A new technique for lipid core plaque detection by optical coherence tomography for prevention of peri-procedural myocardial infarction: A case report
      Rationale: Percutaneous coronary intervention (PCI) provides effective revascularization of atherosclerotic coronary arteries but the invasive nature of treatment can result in complications. Patient concerns: A 53-year old man underwent coronary angiography due to chest pain with minimal ST-segment elevation in the inferior leads of the electrocardiogram. Diagnosis: We proceeded directly to coronary angiography and delineated a moderate stenosis with haziness in the mid right coronary artery (RCA). Interventions: Expert analysis ...
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    10. Imaging outcomes of bioresorbable scaffold overlap: an optical coherence tomography analysis from the ABSORB EXTEND trial

      Imaging outcomes of bioresorbable scaffold overlap: an optical coherence tomography analysis from the ABSORB EXTEND trial
      Aims: The purpose of this study was to assess the vascular response and vessel healing of overlapped Absorb scaffolds (Abbott Vascular, Santa Clara, CA, USA) compared to non-overlapped devices in human coronary arteries as assessed by optical coherence tomography (OCT) in the same treated segment. Methods and results: The ABSORB EXTEND (NCT01023789) trial is a prospective, single-arm, openlabel clinical study which enrolled 800 patients. The planned overlap OCT subgroup in ...
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    11. Is quantitative coronary angiography reliable in assessing the late lumen loss of the everolimus eluting bioresorbable polylactide scaffold in comparison with the cobalt chromium metallic stent?

      Is quantitative coronary angiography reliable in assessing the late lumen loss of the everolimus eluting bioresorbable polylactide scaffold in comparison with the cobalt chromium metallic stent?
      Aims: Immediately after stent/scaffold implantation, quantitative coronary angiography (QCA) with respect to optical coherence tomography (OCT) more severely underestimates the lumen diameter (LD) in Absorb than in XIENCE. This OCT-QCA discrepancy has not been evaluated at long-term follow-up. The present study aimed to assess the accuracy of QCA with reference to OCT in Absorb as compared to XIENCE.
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    12. Fate of post-procedural malapposition of everolimus-eluting polymeric bioresorbable scaffold and everolimus-eluting cobalt chromium metallic stent in human coronary arteries: sequential assessment with optical coherence tomography in ABSORB Japan trial

      Fate of post-procedural malapposition of everolimus-eluting polymeric bioresorbable scaffold and everolimus-eluting cobalt chromium metallic stent in human coronary arteries: sequential assessment with optical coherence tomography in ABSORB Japan trial
      Aims The natural course of post-procedural incomplete strut apposition (ISA) after the implantation of bioresorbable scaffolds (BVS) remains unknown. The purpose of the present study was to evaluate the fate of post-procedural ISA after everolimus-eluting Absorb BVS in comparison with the second-generation everolimus-eluting cobalt chromium stent (CoCr-EES). Methods and results Fate of post-procedural ISA was evaluated by serial optical coherence tomography (OCT) in the ABSORB Japan randomized trial [OCT-1 subgroup ...
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    13. Visualization of extensive intraplaque neovascularization by optical coherence tomography

      Visualization of extensive intraplaque neovascularization by optical coherence tomography
      Inflammation plays a key role in pathogenesis and progression of atherosclerosis (1) . Advent of novel intravascular imaging tools such as Optical Coherence Tomography (OCT) has led to visualization of coronary atherosclerotic plaque characteristics in vivo that were previously seen only on histology. Herein we discuss a case of extensive neovascularization, a feature that imparts vulnerability to atherosclerotic plaque in the coronary artery, as seen by two- and three-dimensional OCT images ...
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    14. Intracoronary optical coherence tomography: Clinical and research applications and intravascular imaging software overview

      Intracoronary optical coherence tomography: Clinical and research applications and intravascular imaging software overview
      By providing valuable information about the coronary artery wall and lumen, intravascular imaging may aid in optimizing interventional procedure results and thereby could improve clinical outcomes following percutaneous coronary intervention (PCI). Intravascular optical coherence tomography (OCT) is a light-based technology with a tissue penetration of approximately 1 to 3 mm and provides near histological resolution. It has emerged as a technological breakthrough in intravascular imaging with multiple clinical and research ...
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    15. Optical coherence tomography assessment of a complex bifurcation lesion treated with double kissing Crush technique: A case report

      Optical coherence tomography assessment of a complex bifurcation lesion treated with double kissing Crush technique: A case report
      The DEFINITION (Impact of the complexity of bifurcation lesions treated with drug-eluting stents) study has provided a novel classification to evaluate the complexity of coronary bifurcation lesion according to coronary angiography, but angiographic imaging due to its low resolution and inherited limitation may result in an inaccurate adjudication. We used optical coherence tomography (OCT) to further evaluate the coronary characteristics in a patient with simple bifurcation lesion which was classified ...
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    16. 1-15 of 293 1 2 3 4 ... 18 19 20 »
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  2. About Erasmus University

    Erasmus Medical Center is the largest and most versatile of the eight university medical centers in the Netherlands. Erasmus MC wants to further extend its international reputation and become one of the twenty best medical institutes in the world by 2013.  Also see The Thoraxcentrum of the Erasmus University Medical Center was founded in 1971 and is an integrated organization of the departments of Cardiology and Cardiothoracic Surgery. The Thoraxcentrum is divided into six medical units and three scientific units: Cardio-Thoracic Surgery, Cardiology, and Biomedical Engineering. The focus of Thoraxcenter Biomedical Engineering is the imaging and diagnosis of cardiovascular disorders. This department is led by Prof. Dr. Ir. A.F.W. van der Steen. The Biomedical Engineering department brings together two technical specialities of the Thoraxcenter, namely: The Experimental Echocardiography group, which investigates the physical and technical aspects of ultrasound for cardiac diagnosis.  Erasmus University Rotterdam is an international knowledge workshop for critical thinking and academic training, driven by a strong focus on current social issues.  The Erasmus MC (medical center) is the university hospital of the city of Rotterdam, The Netherlands. It is affiliated with the Erasmus University.