1. Elena B. Kiseleva

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    1. Mentioned In 28 Articles

    2. Multi-modal optical imaging characterization of atherosclerotic plaques

      Multi-modal optical imaging characterization of atherosclerotic plaques
      We combined cross-polarization optical coherence tomography (CP OCT) and non-linear microscopy based on second harmonic generation (SHG) and two-photon-excited fluorescence (2PEF) to assess collagen and elastin fibers and other vascular structures in the development of atherosclerosis, including identification of vulnerable plaques, which remains an important clinical problem and imaging application. CP OCT's ability to visualize tissue birefringence and cross-scattering adds new information about the microstructure and composition of the ...
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    3. Towards advanced OCT clinical applications

      Towards advanced OCT clinical applications
      In this paper we report on our recent achievement in application of conventional and cross-polarization OCT (CP OCT) modalities for in vivo clinical diagnostics in different medical areas including gynecology, dermatology, and stomatology. In gynecology, CP OCT was employed for diagnosing fallopian tubes and cervix; in dermatology OCT for monitoring of treatment of psoriasis, scleroderma and atopic dermatitis; and in stomatology for diagnosis of oral diseases. For all considered application ...
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    4. The Use of Cross-Polarization OCT in Determining the Dynamics of the State of Pathological and Normal Tissues During Radiation and Photodynamic Therapy

      The Use of Cross-Polarization OCT in Determining the Dynamics of the State of Pathological and Normal Tissues During Radiation and Photodynamic Therapy
      The aim of the investigation was to evaluate the possibilities for using cross-polarization optical coherence tomography (CP OCT) to monitor the effectiveness of treatment of cancer of the mouth cavity and of the cervix uteri after photodynamic therapy (PDT) and radiation therapy (RT). Materials and Methods. The CP OCT investigation was performed with an OCT-1300U (Institute of Applied Physics of the Russian Academy of Sciences, LLC Biomedtech, Russia) tomograph. The ...
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    5. Quantitative Evaluation of the Polarization Characteristics of Coronary Arteries Atherosclerotic Plaques at Different Development Stages

      Quantitative Evaluation of the Polarization Characteristics of Coronary Arteries Atherosclerotic Plaques at Different Development Stages
      The aim of the investigation was to develop an approach to quantitative evaluation of polarization properties (birefringence and cross-scattering) basing on cross-polarization OCT images (CP OCT) in order to characterize the development stages of atherosclerotic plaques and to reveal unstable ones. Materials and Methods. We report on quantitative analysis of CP OCT images of the seven development stages of atherosclerotic plaques ex vivo . Integral depolarization factor (IDF) and effective birefringence ...
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    6. Effects of gamma irradiation on collagen damage and remodeling

      Effects of gamma irradiation on collagen damage and remodeling
      Purpose: The studys objective was to evaluate the dose-time dependences of structural changes occurring in collagen within 24 hours to three months after gamma-irradiation at doses from 2 to 40 Gy in vivo . Materials and methods: Rat's tail tendon was chosen as in vivo model, with its highly ordered collagen structure allowing the changes to be interpreted unambiguously. Macromolecular level (I) was investigated by differential scanning calorimetry (DSC); fibers ...
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    7. Combined use of fluorescence cystoscopy and cross-polarization OCT for diagnosis of bladder cancer and correlation with immunohistochemical markers

      Combined use of fluorescence cystoscopy and cross-polarization OCT for diagnosis of bladder cancer and correlation with immunohistochemical markers
      The combined use of fluorescence cystoscopy and cross-polarization optical coherence tomography (CP OCT) with quantitative estimation of the OCT signal was assessed in 92 bladder zones. It demonstrated the diagnostic accuracy in detecting superficial bladder cancer of 93.6%, sensitivity 96.4%, specificity 92.1%, positive predictive value 87% and negative predictive value 97.9%. Quantitative estimation of OCT signal standard deviation in cross-polarization (CP OCT SD index) makes the ...
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    8. Feature Of The Week 3/13/11: Russian Scientists Investigate Cross Polarization OCT for Early Bladder Cancer Detection

      Feature Of The Week 3/13/11: Russian Scientists Investigate Cross Polarization OCT for Early Bladder Cancer Detection
      Feature Of The Week 3/13/11: This week OCT News has another exciting “Feature Of The Week” presentation of exciting scientific results on the use of co- and cross-polarization OCT information applied to early bladder cancer detection.  The work is from the prestigious Institute of Applied and Fundamental Medicine at the Nizhny Novgorod State Medical Academy and the Institute of Applied Physics of the Russian Academy of Sciences, Nizhny ...
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    9. Cross-polarization optical coherence tomography for early bladder-cancer detection: statistical study

      Cross-polarization optical coherence tomography for early bladder-cancer detection: statistical study
      ...r-cancer detection: statistical study 1. Natalia Gladkova^1,*, 2. Olga Streltsova^2, 3. Elena Zagaynova^1, 4. Elena Kiseleva^1, 5. Valentin Gelikonov^3, 6. Grigory Gelikonov^3, 7. Maria Karabut^1, 8. Katerina Yunusova^2,...
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    10. Advantages of cross-polarization endoscopic optical coherence tomography in diagnosis of bladder neoplasia

      Advantages of cross-polarization endoscopic optical coherence tomography in diagnosis of bladder neoplasia
      ...a Mahadevan-Jansen, E. Duco Jansen ABSTRACT REFERENCES (9) N. D. Gladkova, E. V. Zagaynova, O. S. Streltsova, E. B. Kiseleva, M. M. Karabut, L. B. Snopova, E. E. Yunusova, and E. Tararova Nizhny Novgorod State Medical Ac...
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    11. Application of optical coherence tomography in the diagnosis of mucositis in patients with head and neck cancer during a course of radio(chemo)therapy

      Objective Mucositis is the most common oral complication of non-surgical therapy (chemotherapy, radiotherapy, and radio(chemo)therapy) in patients with head and neck cancer. Growing evidence indicates that more aggressive treatment regimens improve local tumor control and the survival of patients with locally advanced head and neck cancer. However combined therapy approaches are associated with higher acute toxicity. Currently there are no in vivo methods to visualize microscopic changes of ...
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    12. 16-28 of 28 « 1 2
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  2. About Elena B. Kiseleva

    Elena B. Kiseleva

    Elena B. Kiseleva graduated from the N.I. Lobachevsky State Nizhny Novgorod University in 2005 as a specialist in biophysics. Since that time she has been working in the OCT group, Institute of Applied and Fundamental Medicine, Nizhny Novgorod State Medical Academy. Her fields of scientific interests include optical imaging of biotissues – cross-polarization optical coherence tomography, polarization and multiphoton confocal laser scanning microscopy. Also she investigates tissue regeneration after laser surgery.