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2. In Vivo Endoscopic Optical Coherence Tomography of the Healthy Human Oral Mucosa: Qualitative and Quantitative Image Analysis
  
  Explore MDPI Open Access Journals Platform Oct 20 2020
  
  To date, there is still a lack of reliable imaging modalities to improve the quality of consultation, diagnostic and medical examinations of the oral mucosa in dentistry. Even though, optical technologies have become an important element for the detection and treatment of different diseases of soft tissue, for the case of oral screenings the evidence of the benefit in comparison to conventional histopathology is mostly still pending. One promising optical ...
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  Mentions: Julia Walther Dresden University of Technology Edmund Koch
3. Endoscopic Optical Coherence Tomography for Evaluation of Success of Tympanoplasty
  
  Explore LWW Online Jul 14 2020 Otolaryngology
  
  Objective: After tympanoplasty , it is often challenging to differentiate between different causes of a remaining air bone gap (ABG). Optical coherence tomography (OCT) offers a new approach for combined morphologic and functional measurements of the tympanic membrane and adjacent parts of the middle ear. Thus, it provides valuable diagnostic information in patients with a reduced sound transfer after middle ear surgery. Patient and intervention: A patient with history of tympanoplasty ...
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  Mentions: Dresden University of Technology Edmund Koch Lars Kirsten
4. Evaluation of middle ear reconstruction by endoscopic Optical Coherence Tomography
  
  Explore Thieme Jun 24 2020 Otolaryngology
  
  Introduction Endoscopic Optical Coherence Tomography (eOCT) allows high-resolution 3-dimensional imaging of the tympanic membrane and the adjacent areas of the middle ear. Doppler-OCT enables oscillation measurement. Thus, the postoperative outcome of tympanoplasty can be evaluated. Material and Methods 5 Patients were examined after tympanoplasty using eOCT. The system utilizes a near infrared laser with a central wavelength of 1300 nm and a working range of 8 mm. The thickness of ...
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  Mentions: Dresden University of Technology Edmund Koch Lars Kirsten
5. Device and system for doppler optical coherence tomography (OCT) of the human middle ear
  
  Explore uspto.gov Jun 16 2020 Otolaryngology , Patents , Probes
  
  A device for Doppler optical coherence tomography (Doppler OCT), preferably of the human middle ear, is proposed. The device has an endoscope unit for at least partial insertion into the auditory canal. A sound source, a sound receiver, and OCT optics are integrated in the endoscope unit.
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  Mentions: Dresden University of Technology Edmund Koch Lars Kirsten
6. Correlation between Lesion Progression and Depolarization Assessed by Polarization-Sensitive Optical Coherence Tomography
  
  Explore MDPI Open Access Journals Platform Apr 24 2020 Dentistry
  
  The detection of early stages of caries is still one of the major challenges in preservative dentistry. Since it is known from polarized light microscopy (PLM) that intrinsic enamel birefringence is affected by demineralization, polarization-sensitive optical coherence tomography (PSOCT) could facilitate the noninvasive detection and assessment of early carious lesions. The present study aims to correlate enamel lesion progression and depolarization measurements based on PSOCT in an artificial demineralization model ...
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  Mentions: Julia Walther Dresden University of Technology Edmund Koch
7. Polarization-sensitive optical coherence tomography with a conical beam scan for the investigation of birefringence and collagen alignment in the human cervix
  
  Explore OSA | OSA Publishing Jul 25 2019 Gynecology , Probes
  
  ...3(12), 1–9 (2018). [Crossref] [PubMed] J. Golde, F. Tetschke, J. Walther, T. Rosenauer, F. Hempel, C. Hannig, E. Koch, and L. Kirsten, “Detection of carious lesions utilizing depolarization imaging by polarization sensit...
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  Mentions: Brett E. Bouma Christoph K. Hitzenberger James G. Fujimoto
8. Depth-resolved birefringence imaging of collagen fiber organization in the human oral mucosa in vivo
  
  Explore OSA | OSA Publishing Jun 5 2019
  
  Stromal collagen organization has been identified as a potential prognostic indicator in a variety of cancers and other diseases accompanied by fibrosis. Changes in the connective tissue are increasingly considered for grading dysplasia and progress of oral squamous cell carcinoma, investigated mainly ex vivo by histopathology. In this study, polarization-sensitive optical coherence tomography (PS-OCT) with local phase retardation imaging is used for the first time to visualize depth-resolved (i.e ...
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  Mentions: David D. Sampson University of Western Australia Julia Walther
9. Quality Assessment of Tympanoplasty by Means of Endoscopic Optical Coherence Tomography
  
  Explore Thieme May 14 2019 Otolaryngology
  
  Introduction: The endoscopic optical coherence tomography (eOCT) allows the direct, contactless representation and evaluation of the morphology and oscillation behaviour of the tympanic membrane and adjoining tympanic cavity content. After further development of the measuring technology, the eOCT will be able to be used in vivo for the assessment of tympanoplasty results. Materials and Methods: The eOCT was applied to 10 patients after a tympanoplasty with an intact ossicular chain ...
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  Mentions: Julia Walther Dresden University of Technology Edmund Koch
10. Endoscopic Optical Coherence Tomography in Diagnostics of Otosclerosis
  
  Explore Thieme May 14 2019 Otolaryngology
  
  Introduction: Endoscopic Optical Coherence Tomography (eOCT) enables both high-resolution contact-free 3D-imaging of the tympanic membrane and spatial and frequency-resolved oscillation measurement via Doppler-OCT. Thus it is possible to detect causes of conduction hearing loss. In case of otosclerosis, changes in oscillation amplitude at the umbo had been showed via Laser-Doppler-Vibrometry. Material and Methods: The eOCT system utilizes a swept source laser with a wave length around 1300nm. Field-of-view and working ...
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  Mentions: Julia Walther Dresden University of Technology Edmund Koch
11. Endoscopic optical coherence tomography with wide field-of-view for the morphological and functional assessment of the human tympanic membrane
  
  Explore SPIE Digital Library Dec 8 2018 Otolaryngology , Probes
  
  An endoscopic optical coherence tomography (OCT) system with a wide field-of-view of 8 mm is presented, which combines the image capability of endoscopic imaging at the middle ear with the advantages of functional OCT imaging, allowing a morphological and functional assessment of the human tympanic membrane. The endoscopic tube has a diameter of 3.5 mm and contains gradient-index optics for simultaneous forward-viewing OCT and video endoscopy. The endoscope allows ...
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  Mentions: Julia Walther Dresden University of Technology Edmund Koch
12. Visualization of interfacial adhesive defects at dental restorations with spectral domain and polarization sensitive optical coherence tomography
  
  Explore Home Oct 2 2018 Dentistry
  
  Restoration loss based on interfacial adhesive defects and associated caries at the restoration margin are the main causes for invasive replacement of dental restorations. Assessment of the interfacial quality based on clinical inspection and radiographic examination is often difficult and not reliable. In this work, we present spectral domain optical coherence tomography (SDOCT) and polarization sensitive optical coherence tomography (PSOCT) for the evaluation of tooth-composite bond failure. Imaging of two ...
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  Mentions: Julia Walther Dresden University of Technology Edmund Koch
13. Optical Coherence Tomography for NDE (Book Chapter)
  
  Explore Home - Springer Aug 23 2018 NDE/NDT , Textbooks
  
  Optical coherence tomography (OCT) is a noninvasive, high-resolution, interferometric imaging modality using near-infrared light to acquire cross sections and three-dimensional images of the subsurface microstructure of samples. Because of the rapid enhancement of OCT with respect to acquisition speed and axial resolution over the past years, OCT is becoming more and more attractive for applications in nondestructive testing and evaluation. In this chapter, a brief introduction to the technique and ...
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  Mentions: Julia Walther Dresden University of Technology Edmund Koch
14. A System for Clinical Use of Endoscopic Optical Coherence Tomography
  
  Explore Thieme May 1 2018 Otolaryngology , Probes
  
  Introduction: Optical Coherence Tomography (OCT) allows non-invasive high-resolution imaging of tissues. With a penetration depth of a few millimeters it's possible to image the tympanic membrane and the close-by part of the tympanum, e.g. for diagnostics of otitis media and middle ear effusion. In the field of in vivo examination there are difficulties in access to the human tympanic membrane due to the narrow and curved external ear ...
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  Mentions: Julia Walther Dresden University of Technology Edmund Koch
15. Multimodal imaging of lung tissue dynamics in mechanically ventilated rats with optical coherence tomography and intravital microscopy
  
  Explore SPIE Digital Library Mar 20 2018 Pulmonology
  
  The understanding of alveolar mechanics is an essential step towards new and more protective ventilation strategies which are of dare need for the treatment of diseases of lung tissue and the airways. Such ailments become a major task for medical care and health care systems in modern industrial countries in the future. Besides the obvious importance as life-saving intervention, the mechanical strain and processes on the level of gas exchange ...
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  Mentions: Dresden University of Technology Edmund Koch
16. 4D optical coherence tomography for imaging aortic valve dynamics ex vivo
  
  Explore SPIE Digital Library Mar 20 2018 Cardiology
  
  The mechanical components of the heart, especially the valves, are enormously stressed during lifetime and undergo different pathophysiological tissue transformations, which affect cardiac output and in consequence living comfort of affected patients. Calcific aortic valve stenosis (AVS) is the most common valve disease in modern industrial countries but the pathogenesis and progression of this disease is still unknown. Therefore, animal models, especially mouse models, are a powerfull tool to investigate ...
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  Mentions: Dresden University of Technology Edmund Koch
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