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Edmund Koch

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2. Endoscopic optical coherence tomography with wide field-of-view for the morphological and functional assessment of the human tympanic membrane
  
  Explore SPIE Digital Library Dec 8 2018 Otolaryngology , Probes
  
  An endoscopic optical coherence tomography (OCT) system with a wide field-of-view of 8 mm is presented, which combines the image capability of endoscopic imaging at the middle ear with the advantages of functional OCT imaging, allowing a morphological and functional assessment of the human tympanic membrane. The endoscopic tube has a diameter of 3.5 mm and contains gradient-index optics for simultaneous forward-viewing OCT and video endoscopy. The endoscope allows ...
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  Mentions: Julia Walther Dresden University of Technology Edmund Koch
3. Visualization of interfacial adhesive defects at dental restorations with spectral domain and polarization sensitive optical coherence tomography
  
  Explore Home Oct 2 2018 Dentistry
  
  Restoration loss based on interfacial adhesive defects and associated caries at the restoration margin are the main causes for invasive replacement of dental restorations. Assessment of the interfacial quality based on clinical inspection and radiographic examination is often difficult and not reliable. In this work, we present spectral domain optical coherence tomography (SDOCT) and polarization sensitive optical coherence tomography (PSOCT) for the evaluation of tooth-composite bond failure. Imaging of two ...
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  Mentions: Julia Walther Dresden University of Technology Edmund Koch
4. Optical Coherence Tomography for NDE (Book Chapter)
  
  Explore Home - Springer Aug 23 2018 NDE/NDT , Textbooks
  
  Optical coherence tomography (OCT) is a noninvasive, high-resolution, interferometric imaging modality using near-infrared light to acquire cross sections and three-dimensional images of the subsurface microstructure of samples. Because of the rapid enhancement of OCT with respect to acquisition speed and axial resolution over the past years, OCT is becoming more and more attractive for applications in nondestructive testing and evaluation. In this chapter, a brief introduction to the technique and ...
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  Mentions: Julia Walther Dresden University of Technology Edmund Koch
5. A System for Clinical Use of Endoscopic Optical Coherence Tomography
  
  Explore Thieme May 1 2018 Otolaryngology , Probes
  
  Introduction: Optical Coherence Tomography (OCT) allows non-invasive high-resolution imaging of tissues. With a penetration depth of a few millimeters it's possible to image the tympanic membrane and the close-by part of the tympanum, e.g. for diagnostics of otitis media and middle ear effusion. In the field of in vivo examination there are difficulties in access to the human tympanic membrane due to the narrow and curved external ear ...
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  Mentions: Julia Walther Dresden University of Technology Edmund Koch
6. Multimodal imaging of lung tissue dynamics in mechanically ventilated rats with optical coherence tomography and intravital microscopy
  
  Explore SPIE Digital Library Mar 20 2018 Pulmonology
  
  The understanding of alveolar mechanics is an essential step towards new and more protective ventilation strategies which are of dare need for the treatment of diseases of lung tissue and the airways. Such ailments become a major task for medical care and health care systems in modern industrial countries in the future. Besides the obvious importance as life-saving intervention, the mechanical strain and processes on the level of gas exchange ...
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  Mentions: Dresden University of Technology Edmund Koch
7. 4D optical coherence tomography for imaging aortic valve dynamics ex vivo
  
  Explore SPIE Digital Library Mar 20 2018 Cardiology
  
  The mechanical components of the heart, especially the valves, are enormously stressed during lifetime and undergo different pathophysiological tissue transformations, which affect cardiac output and in consequence living comfort of affected patients. Calcific aortic valve stenosis (AVS) is the most common valve disease in modern industrial countries but the pathogenesis and progression of this disease is still unknown. Therefore, animal models, especially mouse models, are a powerfull tool to investigate ...
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  Mentions: Dresden University of Technology Edmund Koch
8. In vivo imaging in the oral cavity by endoscopic optical coherence tomography
  
  Explore SPIE Digital Library Mar 8 2018
  
  The common way to diagnose hard and soft tissue irregularities in the oral cavity is initially the visual inspection by an experienced dentist followed by further medical examinations, such as radiological imaging and/or histopathological investigation. For the diagnosis of oral hard and soft tissues, the detection of early transformations is mostly hampered by poor visual access, low specificity of the diagnosis techniques, and/or limited feasibility of frequent screenings ...
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  Mentions: Julia Walther Dresden University of Technology Edmund Koch
9. Detection of carious lesions utilizing depolarization imaging by polarization sensitive optical coherence tomography
  
  Explore SPIE Digital Library Feb 1 2018 Dentistry
  
  As dental caries is one of the most common diseases, the early and noninvasive detection of carious lesions plays an important role in public health care. Optical coherence tomography (OCT) with its ability of depth-resolved, high-resolution, noninvasive, fast imaging has been previously recognized as a promising tool in dentistry. Additionally, polarization sensitive imaging provides quantitative measures on the birefringent tissue properties and can be utilized for imaging dental tissue, especially ...
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  Mentions: Julia Walther Dresden University of Technology Edmund Koch
10. In vivo imaging of human oral hard and soft tissues by polarization-sensitive optical coherence tomography
  
  Explore SPIE Digital Library Dec 26 2017
  
  Since optical coherence tomography (OCT) provides three-dimensional high-resolution images of biological tissue, the benefit of polarization contrast in the field of dentistry is highlighted in this study. Polarization-sensitive OCT (PS OCT) with phase-sensitive recording is used for imaging dental and mucosal tissues in the human oral cavity in vivo . An enhanced polarization contrast of oral structures is reached by analyzing the signals of the co- and crosspolarized channels of the ...
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  Mentions: Julia Walther Dresden University of Technology Edmund Koch
11. Advanced analysis of domain walls in Mg doped LiNbO3 crystals with high resolution OCT
  
  Explore OSA | OSA Publishing Aug 10 2017 NDE/NDT
  
  The structure of domain walls (DW) in ferroelectric media is of great interest as this material is used for frequency doublers and other applications. We show that the structure of the DWs can nicely be visualized by high resolution optical coherence tomography (OCT). While the high group refractive index of lithium niobate allows a resolution much better than 1 m, the large dispersion can blur the image and has to ...
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  Mentions: Dresden University of Technology Edmund Koch Peter Cimalla
12. Improved Imaging of Magnetically Labeled Cells Using Rotational Magnetomotive Optical Coherence Tomography
  
  Explore MDPI Open Access Journals Platform Apr 27 2017
  
  Abstract In this paper, we present a reliable and robust method for magnetomotive optical coherence tomography (MM-OCT) imaging of single cells labeled with iron oxide particles. This method employs modulated longitudinal and transverse magnetic fields to evoke alignment and rotation of anisotropic magnetic structures in the sample volume. Experimental evidence suggests that magnetic particles assemble themselves in elongated chains when exposed to a permanent magnetic field. Magnetomotion in the intracellular ...
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  Mentions: Dresden University of Technology Edmund Koch
13. Flow Measurement by Lateral Resonant Doppler Optical Coherence Tomography in the Spectral Domain
  
  Explore MDPI Open Access Journals Platform Apr 11 2017
  
  In spectral domain optical coherence tomography (SD-OCT), any transverse motion component of a detected obliquely moving sample results in a nonlinear relationship between the Doppler phase shift and the axial sample velocity restricting phase-resolved Doppler OCT (PR-DOCT). The size of the deviation from the linear relation depends on the amount of the transverse velocity component, given by the Doppler angle, and the height of the absolute sample velocity. Especially for ...
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  Mentions: Julia Walther Dresden University of Technology Edmund Koch
14. Optical Coherence Tomography (OCT) for Time-Resolved Imaging of Alveolar Dynamics in Mechanically Ventilated Rats
  
  Explore MDPI Open Access Journals Platform Mar 15 2017 Pulmonology
  
  Though artificial ventilation is an essential life-saving treatment, the mechanical behavior of lung tissue at the alveolar level is still unknown. Therefore, we need to understand the tissue response during artificial ventilation at this microscale in order to develop new and more protective ventilation methods. Optical coherence tomography (OCT) combined with intravital microscopy (IVM) is a promising tool for visualizing lung tissue dynamics with a high spatial and temporal resolution ...
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  Mentions: Dresden University of Technology Edmund Koch Maria Gaertner
15. Impact of a detector dead time in phase-resolved Doppler analysis using spectral domain optical coherence tomography
  
  Explore OSA | OSA Publishing Jan 20 2017
  
  For any oblique sample movement containing a transverse velocity component, the commonly used linear relationship between the phase shift and the axial velocity component is erroneous for spectrometer-based optical coherence tomography (spectral domain OCT, SD-OCT). We recently proposed a new Doppler model that assumes a continuous integration of the photocurrent. In this research, we extend the model for detectors with a shutter control by taking detector dead time into account ...
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  Mentions: Julia Walther Dresden University of Technology Edmund Koch
16. Doppler optical coherence tomography as a promising tool for detecting fluid in the human middle ear
  
  Explore Home Oct 23 2016 Otolaryngology
  
  The treatment of otitis media requires classifying the effusion in the tympanic cavity for choosing appropriate therapeutic strategies. Otoscopic examination of the middle ear depends on the expertise of the physician and is often hampered in case of inflammatory alterations of the tympanic membrane. In otologic research, optical coherence tomography is an innovative non-invasive imaging technique utilized for visualizing the tympanic membrane. This ex vivo study presents the possibility of ...
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  Mentions: Dresden University of Technology Edmund Koch Lars Kirsten
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