1. Duke University

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    1. Mentioned In 645 Articles

    2. Correlation Of Pathologic Features In Spectral Domain Optical Coherence Tomography With Conventional Retinal Studies.

      We delineated pathologic features within three-dimensional spectral domain optical coherence tomography volumes and projected marked sites of pathologic features onto clinically useful two-dimensional localization maps to be overlaid on conventional clinical images.Page: 298DOI: 10.1097/IAE.0b013e3181567798Authors: STOPA, MARCIN MD *+; BOWER, BRADLEY A. BSE +++; DAVIES, Emily BS *; IZATT, JOSEPH A. PhD *++; TOTH, CYNTHIA A. MD *++
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      Mentions: Duke University
    3. Three-Dimensional Images and Vessel Rendering Using Optical Coherence Tomography

      Optical coherence tomography (OCT) is an emerging technology in dermatology. Translating the principles of ultrasound to use with light waves, OCT captures in vivo images allowing for 3-dimensional reconstruction and Doppler flow measurements. Compared with confocal microscopy, standard OCT has a greater depth of penetration but lower resolution. This places the technology between traditional ultrasound and confocal microscopy in the trade-off between depth penetration and surface resolution (Figure 1). Optical ...
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    4. Molecular imaging of endogenous and exogenous chromophores using ground state recovery pump-probe optical coherence tomography

      Molecular imaging of endogenous and exogenous chromophores using ground state recovery pump-probe optical coherence tomography
      We present a novel molecular imaging technique which combines the 3-D tomographic imaging capability of optical coherence tomography with the molecular sensitivity of pump-probe spectroscopy. This technique, based on transient absorption, is sensitive to any molecular chromophore. It is particularly promising for the many important biomarkers, such as hemoglobin, which are poor fluorophores and therefore difficult to image with current optical techniques without chemical labeling. Previous implementations of pump-probe optical ...
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    5. Method for optical coherence tomography imaging with molecular contrast

      Spatial information, such as concentration and displacement, about a specific molecular contrast agent, may be determined by stimulating a sample containing the agent, thereby altering an optical property of the agent. A plurality of optical coherence tomography (OCT) images may be acquired, at least some of which are acquired at different stimulus intensities. The acquired images are used to profile the molecular contrast agent concentration distribution of the sample.
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    6. System and method for low coherence broadband quadrature interferometry

      A quadrature broadband interferometry system and method obtains a complete complex interferometric signal instantaneously in both homodyne and heterodyne systems in a simple, compact, and inexpensive setup. This is accomplished by separating interferometric components from non-interferometric components in each of at least two detector signals of an interferometer having a number of N.times.N couplers, scaling the interferometric components, and generating real and imaginary parts of a complex interferometric ...
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      Mentions: Duke University
    7. Kinetic acoustic ocular examination apparatus and method

      Soft tissue examination apparatus and method employ an ultrasonic transducer system for generating a series of ultrasound pulses, at least one of which is of sufficiently high intensity to induce physical displacement of the soft tissue. The transducer receives a series of ultrasonic echo pulses and responsively generates a series of data signals indicative of such tissue displacement. A data processor receives the data signals and determines the magnitude of ...
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      Mentions: Duke University
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  2. About Duke University

    Duke University

    Duke University is a private research university located in Durham, North Carolina, USA. Duke University Medical CenterFor more than 75 years, our community of scholars and students has been devoted to understanding the causes, prevention and treatment of human disease. Duke University Eye Center is part of the Medical School.  Duke University's Pratt School of Engineering established The Fitzpatrick Center for Photonics and Communications Systems in December 2000 to help turn North Carolina into a "photon forest" where research and development in photonics would create the kind of technological advance and economic growth found in California's Silicon Valley.

  3. Quotes about Duke University

    1. We are excited to be working with an institution as prestigious as Duke University to advance medical diagnostics.
      In SpectraScience Announces Licensing of Key Technology From Duke University