Spectral Domain Optical Coherence Tomography (SDOCT) has only recently been explored in neonates with retinopathy of prematurity (ROP). Vessel architecture has not been studied. This study provides an SDOCT analysis of vascular features in plus disease in nonsedated neonates.
Objective: Optical coherence tomography (OCT) allows examination of the human retina. While conventional OCT devices are limited mainly to adults, the availability of a handheld system has expanded the use of this technique to pediatric populations, with the primary clinical applications being shaken baby syndrome and retinopathy of prematurity. We sought to apply OCT imaging to neonatal population to assess retinal development. Methods: Subjects imaged at the Duke Neonatal Intensive Care Unit (NICU) and Duke Birthing Center. Subjects were imaged with a Bioptigen Hand Held Probe SD-OCT (HHP-SDOCT) (Bioptigen, Research Triangle Park, NC, USA). For this study, only "normal" subjects ...
Glaucoma diagnosis with imaging devices is difficult because of the variation in axonal count amongst normals. The convergence point of all axons is the optic nerve head and peripapillary retinal nerve fiber layer (RNFL). However, a majority of the ganglion cells (from which the RNFL originates) reside in the macula (40% of the retinal thickness) and since their numbers are relatively constant amongst normals 1, it may be another valuable measurement.
The advent of optical coherence tomography (OCT) has revolutionized our diagnostic and therapeutic capabilities in ophthalmology and vitroretinal disease. In the clinic setting, OCT has touch nearly every aspect of vitreoretinal disease. More recently, OCT has been introduced into the operating room theater. Intraoperative OCT (iOCT) has been uses successfully...
Macular disease in children is routinely recorded in drawings and color photographs, and less commonly through angiography performed under anesthesia. Technhiques used to evaluate function include preferential looking, figure or letter recognition, visual evoked potentials, and electroretiograms.
We describe a novel buffering technique for increasing the A-scan rate of swept source optical coherence tomography (SSOCT) systems employing low duty cycle swept source lasers. This technique differs from previously reported buffering techniques in that it employs a fast optical switch, capable of switching in 60 ns, instead of a fused fiber coupler at the end of the buffering stage, and is therefore appreciably more power efficient. The use of the switch also eliminates patient exposure to light that is not used for imaging that occurs at the end of the laser sweep, thereby increasing the system sensitivity. We ...
Duke University is a private research university located in Durham, North Carolina, USA. Duke University Medical Center. For more than 75 years, our community of scholars and students has been devoted to understanding the causes, prevention and treatment of human disease. Duke University Eye Center is part of the Medical School. Duke University's Pratt School of Engineering established The Fitzpatrick Center for Photonics and Communications Systems in December 2000 to help turn North Carolina into a "photon forest" where research and development in photonics would create the kind of technological advance and economic growth found in California's Silicon Valley.