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1. Mentioned In 591 Articles
2. Deep learning-based classification and segmentation of retinal cavitations on optical coherence tomography images of macular telangiectasia type 2
  
  Explore BJO Online 0 min ago Ophthalmology
  
  Aim: To develop a fully automatic algorithm to segment retinal cavitations on optical coherence tomography (OCT) images of macular telangiectasia type 2 (MacTel2). Methods: The dataset consisted of 99 eyes from 67 participants enrolled in an international, multicentre, phase 2 MacTel2 clinical trial ( NCT01949324 ). Each eye was imaged with spectral-domain OCT at three time points over 2 years. Retinal cavitations were manually segmented by a trained Reader and the retinal ...
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  Mentions: National Institutes of Health Duke University
3. Localized Optical Coherence Tomography Precursors of Macular Atrophy and Fibrotic Scar in the Comparison of Age-Related Macular Degeneration Treatments Trials
  
  Explore American Journal of Ophthalmology Nov 18 2020 Ophthalmology
  
  Purpose To identify precursors of macular atrophy (MA) and of fibrotic scar (FS) in eyes treated with anti-VEGF through pixel-mapping analysis of baseline OCT. Design Cross-sectional analysis. Setting Multicenter clinical trial. Patient population 68 eyes from the Comparison of Age-Related Macular Degeneration Treatments Trials. Intervention Treatment with anti-VEGF agents. Main outcome measure The percentage of MA or FS pixels with each OCT feature at baseline, and the odds ratio (OR ...
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  Mentions: Duke University Cynthia A. Toth Gui-Shuang Ying
4. Repeatability and Reproducibility of Axial and Lateral Measurements on Handheld Optical Coherence Tomography Systems Compared with Tabletop System
  
  Explore TVST Journal Oct 27 2020 Ophthalmology
  
  Purpose : To compare the repeatability and reproducibility of axial and lateral retinal measurements using handheld optical coherence tomography (OCT) systems and a tabletop OCT system. Methods : Graders measured central foveal thickness (CFT), optic nerve-to-fovea distance (OFD), and retinal nerve fiber layer (RNFL) thickness on OCT scans of the right eye of 10 healthy adults. Three OCT systems were used: handheld Leica Envisu, investigational handheld swept-source OCT (UC3), and Heidelberg Spectralis ...
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  Mentions: Heidelberg Engineering Duke University Cynthia A. Toth
5. Farsiu Named Fellow of the Optical Society
  
  Explore pratt.duke.edu Oct 9 2020
  
  Sina Farsiu, the Paul Ruffin Scarborough Distinguished Associate Professor of Engineering, has been named a Fellow of the Optical Society of America (OSA). Farsiu was cited for his outstanding contributions to optical image processing and biophotonics. Farsiu is the director of the Vision and Image Processing Laboratory in Dukes Departments of Biomedical Engineering and Ophthalmology, where he has been instrumental in introducing modern image processing and computation methods into the ...
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  Mentions: Duke University Sina Farsiu
6. Repeatability of Peripapillary Optical Coherence Tomography Angiography Parameters in Older Adults
  
  Explore SAGE Journals Oct 6 2020 Ophthalmology
  
  Purpose: This work assesses the intrasession repeatability of capillary perfusion density (CPD) and capillary flux index (CFI) measurements on peripapillary optical coherence tomography angiography (OCTA) in healthy eyes of older adults. Methods: In this cross-sectional study, healthy volunteers aged 50 years or older underwent 4.5 4.5 mm OCTA imaging centered on the optic nerve head using Zeiss Cirrus HD-5000 AngioPlex (Carl Zeiss Meditec). Two consecutive images were acquired ...
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  Mentions: Duke University Carl Zeiss Meditec
7. Macular Optical Coherence Tomography Characteristics at 36 weeks Postmenstrual Age in Infants Examined for Retinopathy of Prematurity
  
  Explore ScienceDirect Sep 15 2020 Ophthalmology
  
  Objective To report our ability to capture, grade reliably and analyze bedside macular optical coherence tomography (OCT) images from preterm infants and relate OCT findings to biological factors and retinopathy of prematurity (ROP) status at a single time window in the STudy of Eye imaging in Preterm infantS (BabySTEPS). Design Prospective observational study Participants Preterm infants eligible for ROP screening, with parental consent for research and a 361 weeks postmenstrual ...
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  Mentions: Joseph A. Izatt Duke University Sharon F. Freedman
8. A Review of Deep Learning for Screening, Diagnosis, and Detection of Glaucoma Progression
  
  Explore TVST Journal Aug 29 2020 Ophthalmology
  
  Because of recent advances in computing technology and the availability of large datasets, deep learning has risen to the forefront of artificial intelligence, with performances that often equal, or sometimes even exceed, those of human subjects on a variety of tasks, especially those related to image classification and pattern recognition. As one of the medical fields that is highly dependent on ancillary imaging tests, ophthalmology has been in a prime ...
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  Mentions: Duke University Felipe A. Medeiros
9. Artificial Intelligence Mapping of Structure to Function in Glaucoma
  
  Explore TVST Journal Aug 24 2020 Ophthalmology
  
  Purpose : To develop an artificial intelligence (AI)based structure-function (SF) map relating retinal nerve fiber layer (RNFL) damage on spectral domain optical coherence tomography (SDOCT) to functional loss on standard automated perimetry (SAP). Methods : The study included 26,499 pairs of SAP and SDOCT from 15,173 eyes of 8878 patients with glaucoma or suspected of having the disease extracted from the Duke Glaucoma Registry. The data set was randomly ...
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  Mentions: Universidade Federal de São Paulo Duke University Felipe A. Medeiros
10. Auto-Processed Retinal Vessel Shadow View Images From Bedside Optical Coherence Tomography to Evaluate Plus Disease in Retinopathy of Prematurity
  
  Explore TVST Journal Aug 11 2020 Ophthalmology
  
  Abstract Purpose : To describe the creation of en face retinal vessel shadow view (RVSV) optical coherence tomography (OCT) images and assess the feasibility of using these for evaluating vascular disease in preterm infants at risk for retinopathy of prematurity (ROP). Methods : In this exploratory study, we selected images from eyes with a range of ROP vascular disease, prospectively acquired from preterm infants using an investigational, noncontact, handheld, bedside swept-source OCT ...
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  Mentions: Joseph A. Izatt Duke University Sharon F. Freedman
11. Duke University Receives a 2020 NIH Grant for $195,750 for High Speed, Motion-Stabilized, Handheld OCT for Pediatric Imaging
  
  Explore Optical Coherence Tomography News Aug 4 2020 Ophthalmology , Funding
  
  ...sights into the development of the retina in both diseased and normal states.
  Duke University Receives a 2020 NIH Grant for $195,750 for High Speed, Motion-Stabilized, Handheld OCT for Ped...
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  Mentions: Joseph A. Izatt National Institutes of Health Duke University
12. Clustering Spectral-Domain Optical Coherence Tomography Images using a Deep Variational Auto-encoder
  
  Explore IOVS Journal Jul 27 2020 Ophthalmology
  
  Purpose : To learn a low-dimensional representation of spectral-domain optical coherence tomography (SD OCT) peripapillary images that can be used to classify images into glaucoma versus healthy eyes. Methods : The study included 23,992 Spectralis SD OCT images from 1,336 eyes, of which 30% were healthy and the remaining were glaucoma or glaucoma suspects. The definition of groups was based on visual fields and inspection of the optic nerve. In ...
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  Mentions: Duke University
13. Lightweight Learning-based Automatic Segmentation of Subretinal Blebs on Microscope-Integrated Optical Coherence Tomography Images
  
  Explore American Journal of Ophthalmology Jul 20 2020 Ophthalmology
  
  Purpose Subretinal injections of therapeutics are commonly used to treat ocular diseases. Accurate dosing of therapeutics at target locations is crucial but difficult to achieve using subretinal injections due to leakage, and there is no method available to measure the volume of therapeutics successfully administered to the subretinal location during surgery. Here we introduce the first automatic method for quantifying the volume of subretinal blebs, using porcine eyes injected with ...
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  Mentions: Joseph A. Izatt Duke University Cynthia A. Toth
14. Robotics and Virtual Reality for Optical Coherence Tomography-Guided Ophthalmic Surgery and Diagnostics (Thesis)
  
  Explore DukeSpace at Duke University Jul 14 2020 Ophthalmology , Student Theses
  
  Ophthalmology is the only surgical specialty that routinely employs both microsurgical techniques and live intraoperative imaging, especially optical coherence tomography (OCT). Consequently, ophthalmic surgeons routinely face challenges in visualization and manipulation of small ocular tissues or in interpreting intraoperative imaging to guide their actions. This dissertation therefore seeks to advance the state-of-the-art in ophthalmic surgery with regards to manipulation, visualization, and interpretation. First, we address the interpretation challenge in ophthalmic ...
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  Mentions: Duke University Mark Draelos
15. A Comparison of OCT Parameters in Identifying Glaucoma Damage in Eyes Suspected of Having Glaucoma
  
  Explore ScienceDirect Jul 8 2020 Ophthalmology
  
  Purpose To compare retinal nerve fiber layer thickness (RNFLT) and Bruchs membrane opening (BMO) minimum rim width (MRW) measured by spectral-domain (SD) OCT for diagnosing glaucoma in those suspected of having the disease. Design Observational cohort study. Participants One hundred thirteen eyes from 81 patients suspected of having glaucoma based on optic nerve appearance. Methods Participants were imaged using SD OCT, and RNFLT and BMO MRW were measured. All participants ...
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  Mentions: Duke University Felipe A. Medeiros
16. Aphakic contact lens use for improved handheld optical coherence tomography imaging in pediatric aphakic patients
  
  Explore Journal of AAPOS Jul 5 2020 Ophthalmology
  
  Handheld optical coherence tomography (OCT) makes it possible to acquire intraoperative and clinical imaging in infants and children for whom standard OCT is not possible. In patients with a retinal pathology who are left aphakic after surgery, however, image clarity is affected by insufficient refractive correction with handheld OCT. We describe a technique for supplementing the refractive power of the handheld OCT device with an aphakic contact lens to improve ...
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  Mentions: Duke University Cynthia A. Toth
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