1. Duke University

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    1. Mentioned In 407 Articles

    2. Segmentation Based Sparse Reconstruction of Optical Coherence Tomography Images

      Segmentation Based Sparse Reconstruction of Optical Coherence Tomography Images
      We demonstrate the usefulness of utilizing a segmentation step for improving the performance of sparsity based image reconstruction algorithms. In specific, we will focus on retinal optical coherence tomography (OCT) reconstruction and propose a novel segmentation based reconstruction framework with sparse representation, termed segmentation based sparse reconstruction (SSR). The SSR method uses automatically segmented retinal layer information to construct layer-specific structural dictionaries. In addition, the SSR method efficiently exploits patch ...
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    3. Choroidal Findings in Eyes With Birdshot Chorioretinitis Using Enhanced-Depth Optical Coherence Tomography

      Choroidal Findings in Eyes With Birdshot Chorioretinitis Using Enhanced-Depth Optical Coherence Tomography
      Purpose : The purposes of this study were to describe choroidal findings observed using optical coherence tomography with enhanced depth imaging (EDI-OCT) in eyes with birdshot chorioretinitis (BSCR) and to test the hypothesis that these findings are related to participant demographics, clinical characteristics, and treatment. Methods : In a multicenter, cross-sectional study, 172 eyes of 86 individuals with BSCR underwent a standardized clinical evaluation, including defined protocols for EDI-OCT imaging, with macular ...
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    4. Visualizing the Choriocapillaris Under Drusen: Comparing 1050-nm Swept-Source Versus 840-nm Spectral-Domain Optical Coherence Tomography Angiography

      Visualizing the Choriocapillaris Under Drusen: Comparing 1050-nm Swept-Source Versus 840-nm Spectral-Domain Optical Coherence Tomography Angiography
      Purpose : To investigate the appearance of choriocapillaris (CC) flow under drusen by comparing long-wavelength (1050 nm) swept-source optical coherence tomography (SS-OCT) angiography with shorter-wavelength (840 nm) spectral-domain (SD) OCT angiography. Methods : Patients with drusen imaged on both devices on the same day were selected and graded. Ambiguous OCT angiography (OCTA) signal loss was defined as low OCTA signal on the en face OCTA CC image that also had low OCT ...
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    5. Live volumetric (4D) visualization and guidance of in vivo human ophthalmic surgery with intraoperative optical coherence tomography

      Live volumetric (4D) visualization and guidance of in vivo human ophthalmic surgery with intraoperative optical coherence tomography
      Minimally-invasive microsurgery has resulted in improved outcomes for patients. However, operating through a microscope limits depth perception and fixes the visual perspective, which result in a steep learning curve to achieve microsurgical proficiency. We introduce a surgical imaging system employing four-dimensional (live volumetric imaging through time) microscope-integrated optical coherence tomography (4D MIOCT) capable of imaging at up to 10 volumes per second to visualize human microsurgery. A custom stereoscopic heads-up ...
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    6. Method for single illumination source combined optical coherence tomography and fluorescence imaging of fluorescently labeled ocular structures in transgenic mice

      Method for single illumination source combined optical coherence tomography and fluorescence imaging of fluorescently labeled ocular structures in transgenic mice
      In vivo imaging permits longitudinal study of ocular disease processes in the same animal over time. Two different in vivo optical imaging modalities optical coherence tomography (OCT) and fluorescence provide important structural and cellular data respectively about disease processes. In this Methods in Eye Research article, we describe and demonstrate the combination of these two modalities producing a truly simultaneous OCT and fluorescence imaging system for imaging of fluorescently labeled ...
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    7. Use of Optical Coherence Tomography in the Eyes of Children

      Use of Optical Coherence Tomography in the Eyes of Children
      OCT has found its niche within virtually all ophthalmic subspecialties, be it glaucoma, retina/vitreous, or anterior segment. OCTs role in the diagnosis, management, and treatment of pediatric eye disease continues to evolve. Monumental gains have been made in our understanding of various physiologic principles and pathological processes as a result of this relatively new technology. While not intended to be an exhaustive catalogue of the opportunities afforded by OCT ...
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    8. Length-adaptive graph search for automatic segmentation of pathological features in optical coherence tomography images

      Length-adaptive graph search for automatic segmentation of pathological features in optical coherence tomography images
      We introduce a metric in graph search and demonstrate its application for segmenting retinal optical coherence tomography (OCT) images of macular pathology. Our proposed adjusted mean arc length (AMAL) metric is an adaptation of the lowest mean arc length search technique for automated OCT segmentation. We compare this method to Dijkstras shortest path algorithm, which we utilized previously in our popular graph theory and dynamic programming segmentation technique. As an ...
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    9. Spectral domain optical coherence tomography (SD-OCT) Imaging of the Vascular-Avascular junction in the nursery in infants with retinopathy of prematurity

      Spectral domain optical coherence tomography (SD-OCT) Imaging of the Vascular-Avascular junction in the nursery in infants with retinopathy of prematurity
      Since the publication of Foos, there has been little additional microanatomic data on the vascular-avascular junction in retinopathy of prematurity (ROP) in infants. We hypothesize that one could view retinal development across the vascular-avascular (V-AV) junction in infants with ROP using portable bedside SDOCT imaging and novel image analysis.
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    10. Optical coherence tomography macular segmentation as predictor for optic atrophy in children with acute papilledema

      Optical coherence tomography macular segmentation as predictor for optic atrophy in children with acute papilledema
      New Spectralis (Heidelberg, Germany) segmentation software allows automatic quantitation of the thickness of each macular layer. We evaluated the role of Spectralis spectral domain optical coherence tomography (SD-OCT) segmentation in children during acute papilledema to predict the subsequent development of optic atrophy.
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    11. Macular segmentation via optical coherence tomography in pediatric optic nerve head drusen and mild papilledema

      Macular segmentation via optical coherence tomography in pediatric optic nerve head drusen and mild papilledema
      Optic nerve head drusen (ONHD) and papilledema in children can lead to partial optic atrophy, and frequently children with idiopathic intracranial hypertension may have both. The purpose of this study is to use SD-OCT to identify possible subclinical atrophy of the inner macula in eyes of children with pseudopapilledema due to ONHD and mild papilledema.
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    12. 1-15 of 407 1 2 3 4 ... 25 26 27 »
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  2. About Duke University

    Duke University

    Duke University is a private research university located in Durham, North Carolina, USA. Duke University Medical CenterFor more than 75 years, our community of scholars and students has been devoted to understanding the causes, prevention and treatment of human disease. Duke University Eye Center is part of the Medical School.  Duke University's Pratt School of Engineering established The Fitzpatrick Center for Photonics and Communications Systems in December 2000 to help turn North Carolina into a "photon forest" where research and development in photonics would create the kind of technological advance and economic growth found in California's Silicon Valley.

  3. Quotes about Duke University

    1. We are excited to be working with an institution as prestigious as Duke University to advance medical diagnostics.
      In SpectraScience Announces Licensing of Key Technology From Duke University