Articles that mention Duke University -Optical Coherence Tomography News

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1. Mentioned In 549 Articles
2. Noninvasive optical coherence tomography imaging correlates with anatomic and physiologic end-organ changes in healthy normotensives with systemic blood pressure variability
  
  Explore LWW Online Jan 16 2020 Cardiology
  
  Objective Blood pressure variability (BPV) is considered as a novel risk factor for cardiovascular disease including left ventricular hypertrophy, vascular stiffness, and renal dysfunction. In this study, we aimed to determine the relationship between ambulatory BPV with subclinical organ damage and vascular stiffness parameters in normotensive healthy subjects. Methods A total of 100 healthy subjects over 18 years of age were included in this cross-sectional study. We divided the participants ...
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  Mentions: Duke University
3. Beyond Performance Metrics: Automatic Deep Learning Retinal OCT Analysis Reproduces Clinical Trial Outcome
  
  Explore ScienceDirect Dec 28 2019 Ophthalmology
  
  Purpose To validate the efficacy of a fully-automatic, deep learning-based segmentation algorithm beyond conventional performance metrics by measuring the primary outcome of a clinical trial for macular telangiectasia type 2 (MacTel2) Design Evaluation of diagnostic test or technology Participants 92 eyes from 62 participants with MacTel2 from a phase 2 clinical trial (NCT01949324) randomized to one of two treatment groups Methods The ellipsoid zone (EZ) defect areas were measured on ...
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  Mentions: Duke University Sina Farsiu
4. OPTICAL COHERENCE TOMOGRAPHY AND OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY FINDINGS AND VISUAL PROGNOSIS IN TWO PATIENTS WITH POSTERIOR MICROPHTHALMOS
  
  Explore LWW Online Dec 19 2019 Ophthalmology
  
  Background/Purpose: Posterior microphthalmos is a rare ocular condition characterized by a disproportionately small posterior segment and multiple retinal abnormalities. The diagnosis can be challenging, and novel findings on optical coherence tomography ( OCT ) angiography may help to identify this unusual disorder. The purpose of this study is to report OCT and OCT angiography findings in two siblings with posterior microphthalmos . Methods: Case series at an academic eye institute including two ...
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  Mentions: Duke University UCLA
5. Sample Size Requirements of Glaucoma Clinical Trials When Using Combined Optical Coherence Tomography and Visual Field Endpoints
  
  Explore Nature Publishing Group Dec 15 2019 Ophthalmology
  
  Glaucoma clinical trials using visual field (VF) endpoints currently require large sample sizes because of the slowly-progressive nature of this disease. We sought to examine whether the combined use of VF testing and non-invasive optical coherence tomography (OCT) imaging of the neuroretinal tissue could improve the feasibility of such trials. To examine this, we included 192 eyes of 121 glaucoma participants seen at 5 visits over a 2-year period to ...
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  Mentions: Duke University UC Davis University of Melbourne
6. Special Section Guest Editorial: Advances in Retinal Imaging
  
  Explore SPIE Digital Library Dec 12 2019 Ophthalmology
  
  The guest editorial provides an introduction to the Special Section on Advanced Retinal Imaging: Instrumentation, Methods, and Applications. The retina is a peripheral part of the central nerve system (CNS) and shares many similarities with the cerebral cortex. They both have layered anatomy, the same types of functional elements and neurotransmitters, and similar vascular organization and blood-tissue barriers. With far fewer neuronal cell types and simpler anatomical structures, the retina ...
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  Mentions: Duke University Stanford University Boston University
7. Duke University School Receives NIH Grant for Advanced A/LCI systems for Improved Clinical Utility
  
  Explore Optical Coherence Tomography News Dec 10 2019 Gastroenterology , Funding
  
  .... Completion of these aims will yield a clinically incisive diagnostic tool suitable for widespread adoption. Duke University School Receives a 2019 NIH Grant for $436,303 for Advanced A/LCI systems for Improved Clinical...
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  Mentions: Duke University Adam Wax
8. Duke University Engineering Professor Sina Farsiu Elected Fellow of the IEEE
  
  Explore pratt.duke.edu Dec 7 2019
  
  Sina Farsiu , the Paul Ruffin Scarborough Associate Professor of Engineering, and Jeffrey Krolik , professor of electrical and computer engineering, have been named fellows of the Institute of Electrical and Electronics Engineers (IEEE), the world's largest technical professional organization dedicated to advancing technology for the benefit of humanity. Each year, following a rigorous evaluation procedure, the IEEE Fellow Committee recommends a select group of recipients for elevation to IEEE fellow ...
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  Mentions: Duke University Sina Farsiu
9. HANDHELD SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY FINDINGS OF X-LINKED RETINOSCHISIS IN EARLY CHILDHOOD
  
  Explore LWW Online Nov 29 2019 Ophthalmology
  
  Background/Purpose: Using handheld spectral domain optical coherence tomography (SDOCT) imaging to investigate in vivo microanatomic retinal changes and their progression over time in young children with juvenile X-linked retinoschisis (XLRS). Methods: This retrospective analysis was of handheld SD OCT images obtained under a prospective research protocol in children who had established XLRS diagnosis based on genetic testing or clinical history. Three OCT graders performed standardized qualitative and quantitative assessment ...
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  Mentions: Duke University Cynthia A. Toth
10. Optical Coherence Tomography Guided Robotic Needle Insertion for Deep Anterior Lamellar Keratoplasty
  
  Explore IEEE Xplore Nov 26 2019 Ophthalmology
  
  Objective: Deep anterior lamellar keratoplasty (DALK) significantly reduces the post-transplantation morbidity in patients eligible for partial-thickness cornea grafts. The popular "big bubble" technique for DALK is so challenging, however, that a significant fraction of corneal pneumodissection attempts fail for surgeons without extensive DALK-specific experience, even with previous-generation cross-sectional optical coherence tomography (OCT) guidance. We seek to develop robotic, volumetric OCT-guided technology capable of facilitating or automating the difficult needle insertion ...
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  Mentions: Joseph A. Izatt Duke University Anthony N. Kuo
11. Appearance of pediatric choroidal neovascular membranes on optical coherence tomography angiography
  
  Explore Home - Springer Nov 26 2019 Ophthalmology
  
  Purpose Compared with fluorescein angiography (FA), the gold standard for diagnosing choroidal neovascularization (CNV) activity, optical coherence tomography angiography (OCTA) is non-invasive without risks associated with fluorescein dye use, and may be especially advantageous in the diagnosis and monitoring of children with CNV. Methods Eight eyes from eight patients aged 12 months to 18 years were imaged with the investigational Spectralis OCTA (version 6.9, Heidelberg Engineering, Heidelberg, Germany) and ...
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  Mentions: Duke University Cynthia A. Toth
12. Human versus Machine: Comparing a Deep Learning Algorithm to Human Gradings for Detecting Glaucoma on Fundus Photographs
  
  Explore ScienceDirect Nov 18 2019 Ophthalmology
  
  Abstract Purpose To compare the diagnostic performance of human gradings versus predictions provided by a machine-to-machine (M2M) deep learning (DL) algorithm trained to quantify retinal nerve fiber layer (RNFL) damage on fundus photographs. Design Evaluation of a machine learning algorithm. Methods A M2M DL algorithm trained with RNFL thickness parameters from spectral-domain optical coherence tomography was applied to a subset of 490 fundus photos of 490 eyes of 370 subjects ...
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  Mentions: Duke University Felipe A. Medeiros
13. Optical coherence tomography through a rigid borescope applied to quantification of articular cartilage thickness in a porcine knee model
  
  Explore OSA | OSA Publishing Nov 13 2019
  
  There exists an unmet need for an optical coherence tomography (OCT) delivery scheme that is simple, robust, and applicable to general surgical applications. To deliver the beam in a narrow form factor, optical borescopes present an attractive potential solution. We present a method for enabling endoscopic delivery of OCT using a handheld rigid borescope adapted to a low-cost OCT engine. The system reduces the distal profile of the scanner, enabling ...
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  Mentions: Duke University Adam Wax
14. Low-Cost, Portable System Takes OCT Beyond Ophthalmology
  
  Explore pratt.duke.edu Nov 12 2019 Ophthalmology
  
  ...e inside the body has been challenging. In The Optical Society (OSA) journal Optics Letters, researchers from Duke University report how they used a rigid borescope — essentially a thin tube of lenses — to deliver the in...
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  Mentions: Duke University Adam Wax
15. Topography and pachymetry maps for mouse corneas using optical coherence tomography
  
  Explore ScienceDirect Nov 10 2019 Ophthalmology
  
  The majority of the eye's refractive power lies in the cornea, and pathological changes in its shape can affect vision. Small animal models offer an unparalleled degree of control over genetic and environmental factors that can help elucidate mechanisms of diseases affecting corneal shape. However, there is not currently a method to characterize the corneal shape of small animal eyes with topography or pachymetry maps, as is done clinically ...
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  Mentions: Duke University Emory University Georgia Institute of Technology
16. Comparison of Short- And Long-Term Variability On Standard Perimetry and Spectral Domain Optical Coherence Tomography in Glaucoma
  
  Explore American Journal of Ophthalmology Nov 9 2019 Ophthalmology
  
  Purpose To assess short-term and long-term variability on standard automated perimetry (SAP) and spectral domain optical coherence tomography (SD-OCT) in glaucoma. Design Prospective cohort. Methods Ordinary least squares linear regression of SAP mean deviation (MD) and SD-OCT global retinal nerve fiber layer (RNFL) thickness were fitted over time for sequential tests conducted within 5 weeks (short-term testing) and annually (long-term testing). Residuals were obtained by subtracting the predicted and observed ...
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  Mentions: Duke University Felipe A. Medeiros
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