1. Duke University

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    1. Mentioned In 430 Articles

    2. Four-dimensional microscope- integrated optical coherence tomography to enhance visualization in glaucoma surgeries

      Four-dimensional microscope- integrated optical coherence tomography to enhance visualization in glaucoma surgeries
      ..., USA 2 Department of Biomedical Engineering, Duke University, Durham, NC, USA 3 Department of Ophthalmology, Duke University School of Medicine; Department of Biomedical Engineering, Duke University, Durham, NC, USA Cor...
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    3. Review of intraoperative optical coherence tomography: technology and applications [Invited]

      Review of intraoperative optical coherence tomography: technology and applications [Invited]
      During microsurgery, en face imaging of the surgical field through the operating microscope limits the surgeons depth perception and visualization of instruments and sub-surface anatomy. Surgical procedures outside microsurgery, such as breast tumor resections, may also benefit from visualization of the sub-surface tissue structures. The widespread clinical adoption of optical coherence tomography (OCT) in ophthalmology and its growing prominence in other fields, such as cancer imaging, has motivated the development ...
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    4. Comparison of Anterior Segment Optical Coherence Tomography Bleb Grading, Moorfields Bleb Grading System, and Intraocular Pressure After Trabeculectomy

      Comparison of Anterior Segment Optical Coherence Tomography Bleb Grading, Moorfields Bleb Grading System, and Intraocular Pressure After Trabeculectomy
      PURPOSE To compare a novel anterior segment optical coherence tomography (AS-OCT) bleb grading system with a clinical bleb grading system and both with intraocular pressure (IOP) following trabeculectomy surgery. MATERIALS AND METHODS A novel AS-OCT grading system based on bleb size and internal reflectivity was developed. An imaging center was tasked with masked grading of AS-OCT images acquired by multiple surgical sites at postoperative week (POW) 2, postoperative month (POM ...
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    5. Four-dimensional Microscope-Integrated Optical Coherence Tomography to Visualize Suture Depth in Strabismus Surgery

      Four-dimensional Microscope-Integrated Optical Coherence Tomography to Visualize Suture Depth in Strabismus Surgery
      The authors report the use of swept-source microscope-integrated optical coherence tomography (SS-MIOCT), capable of live four-dimensional (three-dimensional across time) intraoperative imaging, to directly visualize suture depth during lateral rectus resection. Key surgical steps visualized in this report included needle depth during partial and full-thickness muscle passes along with scleral passes.
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    6. Stimulated Raman scattering spectroscopic optical coherence tomography

      Stimulated Raman scattering spectroscopic optical coherence tomography
      We integrate spectroscopic optical coherence tomography (SOCT) with stimulated Raman scattering (SRS) to enable simultaneously multiplexed spatial and spectral imaging with sensitivity to many endogenous biochemical species that play an important role in biology and medicine. The combined approach, termed SRS-SOCT, overcomes the limitations of each individual method. Ultimately, SRS-SOCT has the potential to achieve fast, volumetric, and highly sensitive label-free molecular imaging. We demonstrate the approach by imaging excised ...
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    7. Normal-Tension Glaucoma Masqueraders: Detection Using Optical Coherence Tomography

      Normal-Tension Glaucoma Masqueraders: Detection Using Optical Coherence Tomography
      Purpose: Optical coherence tomography (OCT) has become an important tool in the diagnosis and management of glaucoma; however, there can be overlap in the OCT findings between glaucoma and other diseases. We describe the clinical examination finings and interpretation of OCT imaging that led to the diagnosis of glaucoma masqueraders in a clinical case series. Materials and Methods: Four adult patients seen in the glaucoma clinic at the Duke Eye ...
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    8. Wireless, Web-Based Interactive Control of Optical Coherence Tomography with Mobile Devices

      Wireless, Web-Based Interactive Control of Optical Coherence Tomography with Mobile Devices
      Purpose : Optical coherence tomography (OCT) is widely used in ophthalmology clinics and has potential for more general medical settings and remote diagnostics. In anticipation of remote applications, we developed wireless interactive control of an OCT system using mobile devices. Methods : A web-based user interface (WebUI) was developed to interact with a handheld OCT system. The WebUI consisted of key OCT displays and controls ported to a webpage using HTML and ...
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    9. Optical coherence tomography angiography in acute non-arteritic anterior ischaemic optic neuropathy

      Optical coherence tomography angiography in acute non-arteritic anterior ischaemic optic neuropathy
      Purpose To characterise vascular changes in eyes with acute non-arteritic anterior ischaemic optic neuropathy (NAION), using optical coherence tomography angiography (OCT-A) imaging. Methods This hospital-based observational case-control study included included five patients with acute NAION (6 eyes), within 7 days after onset of symptoms and 19 age-matched healthy controls (19 eyes). OCT-A (RTVue XR 100; Optovue, Fremont, California, USA), covering a 4.54.5 mm scan area, was used to ...
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    10. Enhanced visualization of peripheral retinal vasculature with wavefront sensorless adaptive optics optical coherence tomography angiography in diabetic patients

      Enhanced visualization of peripheral retinal vasculature with wavefront sensorless adaptive optics optical coherence tomography angiography in diabetic patients
      Optical coherence tomography angiography (OCTA) is a promising technique for non-invasive visualization of vessel networks in the human eye. We debut a system capable of acquiring wide field-of-view ( 70 70 ) OCT angiograms without mosaicking. Additionally, we report on enhancing the visualization of peripheral microvasculature using wavefront sensorless adaptive optics (WSAO). We employed a fast WSAO algorithm that enabled wavefront correction in 2 s 2s by iterating the mirror shape at ...
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  2. About Duke University

    Duke University

    Duke University is a private research university located in Durham, North Carolina, USA. Duke University Medical CenterFor more than 75 years, our community of scholars and students has been devoted to understanding the causes, prevention and treatment of human disease. Duke University Eye Center is part of the Medical School.  Duke University's Pratt School of Engineering established The Fitzpatrick Center for Photonics and Communications Systems in December 2000 to help turn North Carolina into a "photon forest" where research and development in photonics would create the kind of technological advance and economic growth found in California's Silicon Valley.

  3. Quotes about Duke University

    1. We are excited to be working with an institution as prestigious as Duke University to advance medical diagnostics.
      In SpectraScience Announces Licensing of Key Technology From Duke University