1. Duke University

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    1. Mentioned In 578 Articles

    2. A Comparison of OCT Parameters in Identifying Glaucoma Damage in Eyes Suspected of Having Glaucoma

      A Comparison of OCT Parameters in Identifying Glaucoma Damage in Eyes Suspected of Having Glaucoma
      Purpose To compare retinal nerve fiber layer thickness (RNFLT) and Bruchs membrane opening (BMO) minimum rim width (MRW) measured by spectral-domain (SD) OCT for diagnosing glaucoma in those suspected of having the disease. Design Observational cohort study. Participants One hundred thirteen eyes from 81 patients suspected of having glaucoma based on optic nerve appearance. Methods Participants were imaged using SD OCT, and RNFLT and BMO MRW were measured. All participants ...
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    3. Aphakic contact lens use for improved handheld optical coherence tomography imaging in pediatric aphakic patients

      Aphakic contact lens use for improved handheld optical coherence tomography imaging in pediatric aphakic patients
      Handheld optical coherence tomography (OCT) makes it possible to acquire intraoperative and clinical imaging in infants and children for whom standard OCT is not possible. In patients with a retinal pathology who are left aphakic after surgery, however, image clarity is affected by insufficient refractive correction with handheld OCT. We describe a technique for supplementing the refractive power of the handheld OCT device with an aphakic contact lens to improve ...
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    4. Prevalence, risk factors and impact of posterior staphyloma diagnosed from wide‐field optical coherence tomography in Singapore adults with high myopia

      Prevalence, risk factors and impact of posterior staphyloma diagnosed from wide‐field optical coherence tomography in Singapore adults with high myopia
      Purpose To investigate the prevalence and risk factors of posterior staphyloma using wide‐field optical coherence tomography (WF‐OCT) in adults with high myopia in Singapore. Design Population‐based cross‐sectional study. Methods Adults with spherical equivalent (SE) 5D in either eye at the first visit of Singapore Epidemiology of Eye Diseases study and Singapore Prospective Study Program study were recruited. Posterior staphyloma was diagnosed using WF‐OCT (PLEX Elite9000 ...
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    5. Whole eye optical coherence tomography (OCT) imaging systems and related methods

      Whole eye optical coherence tomography (OCT) imaging systems and related methods
      Whole eye optical coherence tomography (OCT) imaging systems and related methods are disclosed. According to an aspect, an OCT imaging system includes a source having an associated source arm path. Further, the OCT imaging system includes a reference arm coupled to the source arm. Further, the OCT imaging system includes a sample arm having an associated sample arm path and coupled to the source arm. The sample arm includes at ...
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    6. Quantitative topographic curvature maps of the posterior eye utilizing optical coherence tomography

      Quantitative topographic curvature maps of the posterior eye utilizing optical coherence tomography
      Purpose: Deformations of the retina such as staphylomas in myopia or scleral flattening in high intracranial pressure can be challenging to quantify with en face imaging. We describe an OCT based method for the generation of quantitative posterior eye topography maps in normal and pathologic eyes. Methods: Utilizing whole eye OCT we corrected for subjects optical distortions to generate spatially accurate posterior eye OCT volumes and created local curvature ( K ...
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    7. Duke University Receives NIH Grant for Portable Motion-Stabilized Optical Coherence Tomography for Eye Care in Acute Care Settings

      Duke University Receives NIH Grant for Portable Motion-Stabilized Optical Coherence Tomography for Eye Care in Acute Care Settings
      ...ostic capabilities in other settings where specialty eye care may be limited.

      Duke University Receives a 2020 NIH Grant for $400,789 for Portable Motion-Stabilized Optical Coherence Tomogr...

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    8. Overhead Mounted Optical Coherence Tomography in Childhood Glaucoma Evaluation

      Overhead Mounted Optical Coherence Tomography in Childhood Glaucoma Evaluation
      Prcis: Overhead mounted spectral-domain optical coherence tomography enables high quality imaging of the optic nerve and macula in childhood glaucoma and is particularly useful when standard tabletop optical coherence tomography has failed or is not possible. Purpose: Tabletop optical coherence tomography, integral to adult glaucoma management, can be limited in childhood glaucoma patients due to young age, poor cooperation, and/or technical challenges. To address these imaging difficulties, we determined ...
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    9. Duke University Receives NIH Grant for Intrasurgical OCT Image-Guided Robot Assist Device for Partial Thickness Corneal Translation

      Duke University Receives NIH Grant for Intrasurgical OCT Image-Guided Robot Assist Device for Partial Thickness Corneal Translation
      ...scopic 3D guidance using OCT as well as potentially other imaging techniques.

      Duke University Receives a 2020 NIH Grant for $188,771 for Intrasurgical OCT Image-Guided Robot Assist Device ...

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    10. Systems and methods for eye tracking for motion corrected ophthalmic optical coherence tomography

      Systems and methods for eye tracking for motion corrected ophthalmic optical coherence tomography
      Systems and methods for eye tracking for motion corrected ophthalmic optical coherence tomography (OCT) are disclosed. According to an aspect, an imaging system includes an eye tracking device configured to determine movement of an eye. The imaging system also includes an OCT apparatus configured to generate OCT images of a retina of the eye. The OCT apparatus includes a scanner operable to be moved for relocating an OCT scan pivot ...
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    11. a/LCI-OCT Pilot in Esophagus

      a/LCI-OCT Pilot in Esophagus
      This study will test a newly developed dual modality probe, including optical coherence tomography (OCT) and angle-resolved low-coherence interferometry (a/LCI), in the human esophagus to determine 1) whether adequate tissue contact can be attained by the probe to acquire high quality images, and 2) to identify if these images can discern whether the imaged tissue is squamous or Barrett's Esophagus (BE) epithelium. This pilot study will test the ...
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    12. Reversal of Cupping in an Infant, Shown by Optical Coherence Tomography

      Reversal of Cupping in an Infant, Shown by Optical Coherence Tomography
      A 10-month-old white male infant with primary congenital glaucoma underwent successful goniotomy in the right eye, lowering intraocular pressure from 34 mm Hg to 11 mm Hg and decreasing axial length from 23.4 mm to 22.8 mm. We used optical coherence tomography (HRA+OCT Spectralis with Flex module [Heidelberg Engineering]) to image the optic nerve preoperatively and at 1 month postoperatively. The cup-disc ratio decreased from 0.6 ...
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    13. Spectroscopic optical coherence refraction tomography

      Spectroscopic optical coherence refraction tomography
      In optical coherence tomography (OCT), the axial resolution is often superior to the lateral resolution, which is sacrificed for long imaging depths. To address this anisotropy, we previously developed optical coherence refraction tomography (OCRT), which uses images from multiple angles to computationally reconstruct an image with isotropic resolution, given by the OCT axial resolution. On the other hand, spectroscopic OCT (SOCT), an extension of OCT, trades axial resolution for spectral ...
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    14. OCULAR MANIFESTATIONS OF PORETTI-BOLTSHAUSER SYNDROME: FINDINGS FROM MULTIMODAL IMAGING AND ELECTROPHYSIOLOG

      OCULAR MANIFESTATIONS OF PORETTI-BOLTSHAUSER SYNDROME: FINDINGS FROM MULTIMODAL IMAGING AND ELECTROPHYSIOLOG
      Background/Purpose: Poretti-Boltshauser syndrome is a rare, nonprogressive neurologic syndrome with characteristic cerebellar cysts on neuroimaging due to mutations in LAMA1 . The ophthalmic findings in Poretti-Boltshauser syndrome are not well described. Here, we report the ophthalmic findings from multimodal imaging and electrophysiology of a patient with genetically confirmed Poretti-Boltshauser syndrome . Methods: A 3-year-old boy with confirmed mutations in LAMA1 underwent examination under anesthesia with electroretinography and multimodal imaging including fundus ...
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    15. 1-15 of 578 1 2 3 4 ... 37 38 39 »
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  2. About Duke University

    Duke University

    Duke University is a private research university located in Durham, North Carolina, USA. Duke University Medical CenterFor more than 75 years, our community of scholars and students has been devoted to understanding the causes, prevention and treatment of human disease. Duke University Eye Center is part of the Medical School.  Duke University's Pratt School of Engineering established The Fitzpatrick Center for Photonics and Communications Systems in December 2000 to help turn North Carolina into a "photon forest" where research and development in photonics would create the kind of technological advance and economic growth found in California's Silicon Valley.

  3. Quotes about Duke University

    1. We are excited to be working with an institution as prestigious as Duke University to advance medical diagnostics.
      In SpectraScience Announces Licensing of Key Technology From Duke University