1. Duke University

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    1. Mentioned In 544 Articles

    2. Duke University Engineering Professor Sina Farsiu Elected Fellow of the IEEE

      Duke University Engineering Professor Sina Farsiu Elected Fellow of the IEEE
      Sina Farsiu , the Paul Ruffin Scarborough Associate Professor of Engineering, and Jeffrey Krolik , professor of electrical and computer engineering, have been named fellows of the Institute of Electrical and Electronics Engineers (IEEE), the world's largest technical professional organization dedicated to advancing technology for the benefit of humanity. Each year, following a rigorous evaluation procedure, the IEEE Fellow Committee recommends a select group of recipients for elevation to IEEE fellow ...
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    3. HANDHELD SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY FINDINGS OF X-LINKED RETINOSCHISIS IN EARLY CHILDHOOD

      HANDHELD SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY FINDINGS OF X-LINKED RETINOSCHISIS IN EARLY CHILDHOOD
      Background/Purpose: Using handheld spectral domain optical coherence tomography (SDOCT) imaging to investigate in vivo microanatomic retinal changes and their progression over time in young children with juvenile X-linked retinoschisis (XLRS). Methods: This retrospective analysis was of handheld SD OCT images obtained under a prospective research protocol in children who had established XLRS diagnosis based on genetic testing or clinical history. Three OCT graders performed standardized qualitative and quantitative assessment ...
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    4. Optical Coherence Tomography Guided Robotic Needle Insertion for Deep Anterior Lamellar Keratoplasty

      Optical Coherence Tomography Guided Robotic Needle Insertion for Deep Anterior Lamellar Keratoplasty
      Objective: Deep anterior lamellar keratoplasty (DALK) significantly reduces the post-transplantation morbidity in patients eligible for partial-thickness cornea grafts. The popular "big bubble" technique for DALK is so challenging, however, that a significant fraction of corneal pneumodissection attempts fail for surgeons without extensive DALK-specific experience, even with previous-generation cross-sectional optical coherence tomography (OCT) guidance. We seek to develop robotic, volumetric OCT-guided technology capable of facilitating or automating the difficult needle insertion ...
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    5. Appearance of pediatric choroidal neovascular membranes on optical coherence tomography angiography

      Appearance of pediatric choroidal neovascular membranes on optical coherence tomography angiography
      Purpose Compared with fluorescein angiography (FA), the gold standard for diagnosing choroidal neovascularization (CNV) activity, optical coherence tomography angiography (OCTA) is non-invasive without risks associated with fluorescein dye use, and may be especially advantageous in the diagnosis and monitoring of children with CNV. Methods Eight eyes from eight patients aged 12 months to 18 years were imaged with the investigational Spectralis OCTA (version 6.9, Heidelberg Engineering, Heidelberg, Germany) and ...
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    6. Human versus Machine: Comparing a Deep Learning Algorithm to Human Gradings for Detecting Glaucoma on Fundus Photographs

      Human versus Machine: Comparing a Deep Learning Algorithm to Human Gradings for Detecting Glaucoma on Fundus Photographs
      Abstract Purpose To compare the diagnostic performance of human gradings versus predictions provided by a machine-to-machine (M2M) deep learning (DL) algorithm trained to quantify retinal nerve fiber layer (RNFL) damage on fundus photographs. Design Evaluation of a machine learning algorithm. Methods A M2M DL algorithm trained with RNFL thickness parameters from spectral-domain optical coherence tomography was applied to a subset of 490 fundus photos of 490 eyes of 370 subjects ...
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    7. Optical coherence tomography through a rigid borescope applied to quantification of articular cartilage thickness in a porcine knee model

      Optical coherence tomography through a rigid borescope applied to quantification of articular cartilage thickness in a porcine knee model
      There exists an unmet need for an optical coherence tomography (OCT) delivery scheme that is simple, robust, and applicable to general surgical applications. To deliver the beam in a narrow form factor, optical borescopes present an attractive potential solution. We present a method for enabling endoscopic delivery of OCT using a handheld rigid borescope adapted to a low-cost OCT engine. The system reduces the distal profile of the scanner, enabling ...
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    8. Topography and pachymetry maps for mouse corneas using optical coherence tomography

      Topography and pachymetry maps for mouse corneas using optical coherence tomography
      The majority of the eye's refractive power lies in the cornea, and pathological changes in its shape can affect vision. Small animal models offer an unparalleled degree of control over genetic and environmental factors that can help elucidate mechanisms of diseases affecting corneal shape. However, there is not currently a method to characterize the corneal shape of small animal eyes with topography or pachymetry maps, as is done clinically ...
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    9. Comparison of Short- And Long-Term Variability On Standard Perimetry and Spectral Domain Optical Coherence Tomography in Glaucoma

      Comparison of Short- And Long-Term Variability On Standard Perimetry and Spectral Domain Optical Coherence Tomography in Glaucoma
      Purpose To assess short-term and long-term variability on standard automated perimetry (SAP) and spectral domain optical coherence tomography (SD-OCT) in glaucoma. Design Prospective cohort. Methods Ordinary least squares linear regression of SAP mean deviation (MD) and SD-OCT global retinal nerve fiber layer (RNFL) thickness were fitted over time for sequential tests conducted within 5 weeks (short-term testing) and annually (long-term testing). Residuals were obtained by subtracting the predicted and observed ...
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    10. Analysis of Neuroretinal Rim by Age, Race, and Sex Using High-Density 3-Dimensional Spectral-Domain Optical Coherence Tomography

      Analysis of Neuroretinal Rim by Age, Race, and Sex Using High-Density 3-Dimensional Spectral-Domain Optical Coherence Tomography
      rcis: Neuroretinal rim minimum distance band (MDB) thickness is significantly lower in older subjects and African Americans compared with whites. It is similar in both sexes. Purpose: To evaluate the relationship between age, race, and sex with the neuroretinal rim using high-density spectral-domain optical coherence tomography optic nerve volume scans of normal eyes. Methods: A total of 256 normal subjects underwent Spectralis spectral-domain optical coherence tomography optic nerve head volume ...
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    11. Analysis of Neuroretinal Rim by Age, Race, and Gender Using High-Density Three-Dimensional Spectral Domain Optical Coherence Tomography

      Analysis of Neuroretinal Rim by Age, Race, and Gender Using High-Density Three-Dimensional Spectral Domain Optical Coherence Tomography
      Prcis: Neuroretinal rim minimum distance band thickness is significantly lower in older subjects and African Americans compared to Caucasians. It is similar in both genders. Purpose: To evaluate the relationship between age, race, and gender with the neuroretinal rim using high-density spectral domain optical coherence tomography (SD-OCT) optic nerve volume scans of normal eyes. Methods: 256 normal subjects underwent Spectralis (Heidelberg Engineering, Heidelberg, Germany) SD-OCT optic nerve head volume scans ...
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    12. Characterization of dry eye disease in a mouse model by optical coherence tomography and fluorescein staining

      Characterization of dry eye disease in a mouse model by optical coherence tomography and fluorescein staining
      A custom-built ultrahigh-resolution optical coherence tomography (UHR-OCT) system and fluorescein staining were employed for investigation of a scopolamine induced dry eye mouse model. Acquired data was used to evaluate common and complementary findings of the two modalities. Central corneal thickness as measured by UHR-OCT increased significantly over the study period of 24 hours, from 89.03.57 m to 92.24.07 m. Both techniques were able to show corneal ...
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    13. Optical coherence refraction tomography

      Optical coherence refraction tomography
      Optical coherence tomography (OCT) is a cross-sectional, micrometre-scale imaging modality with widespread clinical application. Typical OCT systems sacrifice lateral resolution to achieve long depths of focus for bulk tissue imaging, and therefore tend to have better axial than lateral resolution. Such anisotropic resolution can obscure fine ultrastructural features. Furthermore, conventional OCT suffers from refraction-induced image distortions. Here, we introduce optical coherence refraction tomography (OCRT), which extends the superior axial resolution ...
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    14. 1-15 of 544 1 2 3 4 ... 35 36 37 »
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  2. About Duke University

    Duke University

    Duke University is a private research university located in Durham, North Carolina, USA. Duke University Medical CenterFor more than 75 years, our community of scholars and students has been devoted to understanding the causes, prevention and treatment of human disease. Duke University Eye Center is part of the Medical School.  Duke University's Pratt School of Engineering established The Fitzpatrick Center for Photonics and Communications Systems in December 2000 to help turn North Carolina into a "photon forest" where research and development in photonics would create the kind of technological advance and economic growth found in California's Silicon Valley.

  3. Quotes about Duke University

    1. We are excited to be working with an institution as prestigious as Duke University to advance medical diagnostics.
      In SpectraScience Announces Licensing of Key Technology From Duke University