1. Duke University

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    1. Mentioned In 586 Articles

    2. Macular Optical Coherence Tomography Characteristics at 36 weeks Postmenstrual Age in Infants Examined for Retinopathy of Prematurity

      Macular Optical Coherence Tomography Characteristics at 36 weeks Postmenstrual Age in Infants Examined for Retinopathy of Prematurity
      Objective To report our ability to capture, grade reliably and analyze bedside macular optical coherence tomography (OCT) images from preterm infants and relate OCT findings to biological factors and retinopathy of prematurity (ROP) status at a single time window in the STudy of Eye imaging in Preterm infantS (BabySTEPS). Design Prospective observational study Participants Preterm infants eligible for ROP screening, with parental consent for research and a 361 weeks postmenstrual ...
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    3. A Review of Deep Learning for Screening, Diagnosis, and Detection of Glaucoma Progression

      A Review of Deep Learning for Screening, Diagnosis, and Detection of Glaucoma Progression
      Because of recent advances in computing technology and the availability of large datasets, deep learning has risen to the forefront of artificial intelligence, with performances that often equal, or sometimes even exceed, those of human subjects on a variety of tasks, especially those related to image classification and pattern recognition. As one of the medical fields that is highly dependent on ancillary imaging tests, ophthalmology has been in a prime ...
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    4. Artificial Intelligence Mapping of Structure to Function in Glaucoma

      Artificial Intelligence Mapping of Structure to Function in Glaucoma
      Purpose : To develop an artificial intelligence (AI)based structure-function (SF) map relating retinal nerve fiber layer (RNFL) damage on spectral domain optical coherence tomography (SDOCT) to functional loss on standard automated perimetry (SAP). Methods : The study included 26,499 pairs of SAP and SDOCT from 15,173 eyes of 8878 patients with glaucoma or suspected of having the disease extracted from the Duke Glaucoma Registry. The data set was randomly ...
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    5. Auto-Processed Retinal Vessel Shadow View Images From Bedside Optical Coherence Tomography to Evaluate Plus Disease in Retinopathy of Prematurity

      Auto-Processed Retinal Vessel Shadow View Images From Bedside Optical Coherence Tomography to Evaluate Plus Disease in Retinopathy of Prematurity
      Abstract Purpose : To describe the creation of en face retinal vessel shadow view (RVSV) optical coherence tomography (OCT) images and assess the feasibility of using these for evaluating vascular disease in preterm infants at risk for retinopathy of prematurity (ROP). Methods : In this exploratory study, we selected images from eyes with a range of ROP vascular disease, prospectively acquired from preterm infants using an investigational, noncontact, handheld, bedside swept-source OCT ...
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    6. Clustering Spectral-Domain Optical Coherence Tomography Images using a Deep Variational Auto-encoder

      Clustering Spectral-Domain Optical Coherence Tomography Images using a Deep Variational Auto-encoder
      Purpose : To learn a low-dimensional representation of spectral-domain optical coherence tomography (SD OCT) peripapillary images that can be used to classify images into glaucoma versus healthy eyes. Methods : The study included 23,992 Spectralis SD OCT images from 1,336 eyes, of which 30% were healthy and the remaining were glaucoma or glaucoma suspects. The definition of groups was based on visual fields and inspection of the optic nerve. In ...
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      Mentions: Duke University
    7. Lightweight Learning-based Automatic Segmentation of Subretinal Blebs on Microscope-Integrated Optical Coherence Tomography Images

      Lightweight Learning-based Automatic Segmentation of Subretinal Blebs on Microscope-Integrated Optical Coherence Tomography Images
      Purpose Subretinal injections of therapeutics are commonly used to treat ocular diseases. Accurate dosing of therapeutics at target locations is crucial but difficult to achieve using subretinal injections due to leakage, and there is no method available to measure the volume of therapeutics successfully administered to the subretinal location during surgery. Here we introduce the first automatic method for quantifying the volume of subretinal blebs, using porcine eyes injected with ...
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    8. Robotics and Virtual Reality for Optical Coherence Tomography-Guided Ophthalmic Surgery and Diagnostics (Thesis)

      Robotics and Virtual Reality for Optical Coherence Tomography-Guided Ophthalmic Surgery and Diagnostics (Thesis)
      Ophthalmology is the only surgical specialty that routinely employs both microsurgical techniques and live intraoperative imaging, especially optical coherence tomography (OCT). Consequently, ophthalmic surgeons routinely face challenges in visualization and manipulation of small ocular tissues or in interpreting intraoperative imaging to guide their actions. This dissertation therefore seeks to advance the state-of-the-art in ophthalmic surgery with regards to manipulation, visualization, and interpretation. First, we address the interpretation challenge in ophthalmic ...
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    9. A Comparison of OCT Parameters in Identifying Glaucoma Damage in Eyes Suspected of Having Glaucoma

      A Comparison of OCT Parameters in Identifying Glaucoma Damage in Eyes Suspected of Having Glaucoma
      Purpose To compare retinal nerve fiber layer thickness (RNFLT) and Bruchs membrane opening (BMO) minimum rim width (MRW) measured by spectral-domain (SD) OCT for diagnosing glaucoma in those suspected of having the disease. Design Observational cohort study. Participants One hundred thirteen eyes from 81 patients suspected of having glaucoma based on optic nerve appearance. Methods Participants were imaged using SD OCT, and RNFLT and BMO MRW were measured. All participants ...
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    10. Aphakic contact lens use for improved handheld optical coherence tomography imaging in pediatric aphakic patients

      Aphakic contact lens use for improved handheld optical coherence tomography imaging in pediatric aphakic patients
      Handheld optical coherence tomography (OCT) makes it possible to acquire intraoperative and clinical imaging in infants and children for whom standard OCT is not possible. In patients with a retinal pathology who are left aphakic after surgery, however, image clarity is affected by insufficient refractive correction with handheld OCT. We describe a technique for supplementing the refractive power of the handheld OCT device with an aphakic contact lens to improve ...
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    11. Prevalence, risk factors and impact of posterior staphyloma diagnosed from wide‐field optical coherence tomography in Singapore adults with high myopia

      Prevalence, risk factors and impact of posterior staphyloma diagnosed from wide‐field optical coherence tomography in Singapore adults with high myopia
      Purpose To investigate the prevalence and risk factors of posterior staphyloma using wide‐field optical coherence tomography (WF‐OCT) in adults with high myopia in Singapore. Design Population‐based cross‐sectional study. Methods Adults with spherical equivalent (SE) 5D in either eye at the first visit of Singapore Epidemiology of Eye Diseases study and Singapore Prospective Study Program study were recruited. Posterior staphyloma was diagnosed using WF‐OCT (PLEX Elite9000 ...
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    12. Whole eye optical coherence tomography (OCT) imaging systems and related methods

      Whole eye optical coherence tomography (OCT) imaging systems and related methods
      Whole eye optical coherence tomography (OCT) imaging systems and related methods are disclosed. According to an aspect, an OCT imaging system includes a source having an associated source arm path. Further, the OCT imaging system includes a reference arm coupled to the source arm. Further, the OCT imaging system includes a sample arm having an associated sample arm path and coupled to the source arm. The sample arm includes at ...
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    13. Quantitative topographic curvature maps of the posterior eye utilizing optical coherence tomography

      Quantitative topographic curvature maps of the posterior eye utilizing optical coherence tomography
      Purpose: Deformations of the retina such as staphylomas in myopia or scleral flattening in high intracranial pressure can be challenging to quantify with en face imaging. We describe an OCT based method for the generation of quantitative posterior eye topography maps in normal and pathologic eyes. Methods: Utilizing whole eye OCT we corrected for subjects optical distortions to generate spatially accurate posterior eye OCT volumes and created local curvature ( K ...
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    14. Duke University Receives NIH Grant for Portable Motion-Stabilized Optical Coherence Tomography for Eye Care in Acute Care Settings

      Duke University Receives NIH Grant for Portable Motion-Stabilized Optical Coherence Tomography for Eye Care in Acute Care Settings
      ...ostic capabilities in other settings where specialty eye care may be limited.

      Duke University Receives a 2020 NIH Grant for $400,789 for Portable Motion-Stabilized Optical Coherence Tomogr...

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    15. 1-15 of 586 1 2 3 4 ... 37 38 39 »
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  2. About Duke University

    Duke University

    Duke University is a private research university located in Durham, North Carolina, USA. Duke University Medical CenterFor more than 75 years, our community of scholars and students has been devoted to understanding the causes, prevention and treatment of human disease. Duke University Eye Center is part of the Medical School.  Duke University's Pratt School of Engineering established The Fitzpatrick Center for Photonics and Communications Systems in December 2000 to help turn North Carolina into a "photon forest" where research and development in photonics would create the kind of technological advance and economic growth found in California's Silicon Valley.

  3. Quotes about Duke University

    1. We are excited to be working with an institution as prestigious as Duke University to advance medical diagnostics.
      In SpectraScience Announces Licensing of Key Technology From Duke University