1. Dresden University of Technology

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    1. Mentioned In 114 Articles

    2. Optical coherence tomography of macular thickness after biaxial vs coaxial microincision clear corneal cataract surgery

      Purpose. To evaluate macular thickness changes after biaxial microincision versus coaxial small incision cataract surgery using optical coherence tomography (OCT). Methods. This prospective, randomized, marked study comprised 70 patients (70 eyes) undergoing biaxial microincision surgery or conventional coaxial phacoemulsification. Patients were evaluated by Stratus OCT preoperatively and 1 day, 4 weeks, and 8 weeks postoperatively. Best-corrected visual acuity (BCVA), phacoemulsification power, and effective phacoemulsification time (EPT) were evaluated. Results. In ...
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    3. Simultaneous dual-band optical coherence tomography in the spectral domain for high resolution in vivo imaging

      Simultaneous dual-band optical coherence tomography in the spectral domain for high resolution in vivo imaging
      ptical coherence tomography (OCT) in the spectral domain is demonstrated simultaneously at two wavelength bands centered at 800 nm and 1250 nm. A novel commercial supercontinuum laser is applied as a single low coherence broadband light source. The emission spectrum of the source is shaped by optical and spatial filtering in order to achieve an adequate double peak spectrum containing the wavelength bands 700 - 900 nm and 1100 - 1400 nm ...
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    4. Optical Coherence Tomography System And Optical Coherence Tomography Method (Wo 2009/124569)

      Optical Coherence Tomography System And Optical Coherence Tomography Method (Wo 2009/124569)
      The invention relates to an optical coherence tomography system comprising an interferometer, in particular a Michelson-interferometer, provided with a reference arm (R) for modifying an optical reference wave length and a measuring arm (M), in which an object (sample P) that is to be scanned can be arranged and/or is arranged in a sample volume (PV). Said optical coherence tomography device is characterised in that a focusing system (F ...
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    5. Transverse motion as a source of noise and reduced correlation of the Doppler phase shift 
in spectral domain OCT

      Transverse motion as a source of noise and reduced correlation of the Doppler phase shift 
in spectral domain OCT
      Recently, a new phase-resolved Doppler model was presented for spectral domain optical coherence tomography (SD OCT) showing that the linear relation between the axial velocity component of the obliquely moving sample and the phase difference of consecutive A-Scans does not hold true in the presence of a transverse velocity component which is neglected in the widely-used classic Doppler analysis. Besides taking note of the new non-proportional relationship of phase shift ...
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    6. Simultaneous dual-band optical coherence tomography in the spectral domain for high resolution in vivo imaging

      Simultaneous dual-band optical coherence tomography in the spectral domain for high resolution in vivo imaging
      Optical coherence tomography (OCT) in the spectral domain is demonstrated simultaneously at two wavelength bands centered at 800 nmand 1250 nm. A novel commercial supercontinuum laser is applied as a single low coherence broadband light source. The emission spectrum of the source is shaped by optical and spatial filtering in order to achieve anadequate double peak spectrum containing the wavelength bands 700 - 900nm and 1100 - 1400 nm for dual-band OCT ...
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    7. Simultaneous three-dimensional optical coherence tomography and intravital microscopy for imaging subpleural pulmonary alveoli in isolated rabbit lungs

      There is a growing interest in analyzing lung mechanics at the level of the alveoli in order to understand stress-related pathogenesis and possibly avoid ventilator associated lung injury. Emerging quantitative models to simulate fluid mechanics and the associated stresses and strains on delicate alveolar walls require realistic quantitative input on alveolar geometry and its dynamics during ventilation. Here, three-dimensional optical coherence tomography (OCT) and conventional intravital microscopy are joined in ...
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    8. Alveolar dynamics in acute lung injury: Heterogeneous distension rather than cyclic opening and collapse *

      Objectives: To analyze alveolar dynamics in healthy and acid-injured lungs of ventilated mice. Protective ventilation is potentially lifesaving in patients with acute lung injury. However, optimization of ventilation strategies is hampered by an incomplete understanding of the effects of mechanical ventilation at the alveolar level. Design: In anesthetized and ventilated Balb/c mice, subpleural alveoli were visualized by darkfield intravital microscopy and optical coherence tomography. Setting: Animal research laboratory. Subjects ...
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    9. Resonant Doppler imaging with common path OCT

      Resonant Doppler flow imaging based on optical coherence tomography (OCT) is a recently developed imaging modality that provides, besides the structural information, dynamic blood flow information. We show that this method can be applied to a common path OCT system by mounting the mirror in the reference arm on a small piezo actor leading to a simpler and more stable system design. Besides the known 3 state cycle, we describe ...
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    10. Blood flow measurement in the in vivo mouse model by the combination of Doppler OCT and the signal power decrease in spectral domain OCT

      Blood flow measurement with spectrometer-based Fourier domain optical coherence tomography (FD OCT) is limited by the motion-induced signal fading and the resulting reduction of flow sensitivity. In this study, a combination of the established Doppler OCT and the numerically simulated signal damping due to obliquely moved scatterers is used to estimate the systolic blood flow velocities in the in vivo mouse model at which the standard Doppler OCT does not ...
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    11. In-vivo Fourier domain optical coherence tomography as a new tool for investigation of vasodynamics in the mouse model

      In-vivo imaging of the vascular system can provide novel insight into the dynamics of vasoconstriction and vasodilation. Fourier domain optical coherence tomography (FD-OCT) is an optical, noncontact imaging technique based on interferometry of short-coherent near-infrared light with axial resolution of less than 10 µm. In this study, we apply FD-OCT as an in-vivo imaging technique to investigate blood vessels in their anatomical context using temporally resolved image stacks. Our chosen ...
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    12. Analysis of in vitro and in vivo bidirectional flow velocities by phase-resolved doppler fourier-domain OCT

      Fourier-domain Optical Coherence Tomography (FD-OCT) is a non-invasive imaging technique which allows the in vivo examination of subsurface tissue. Besides the structural imaging, FD-OCT is capable to measure blood flow velocities. This method is referred to as phase-resolved Doppler FD-OCT and often used in small retinal vessels (diameters about 100 μm) with low blood flow velocities. In this study, we present a FD-OCT system with a spectrum read-out rate of ...
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    13. 91-105 of 114 « 1 2 3 4 5 6 7 8 »
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  2. About Dresden University of Technology

    Dresden University of Technology

    Dresden University of Technology (Technische Universität Dresde) is the largest institute of higher education in the city of Dresden, the largest university in Saxony and one of the 10 largest universities in Germany with 34,993 students as of 2006. The name Technische Universität Dresden has only been used since 1961; the history of the university, however, goes back nearly 200 years to 1828. This makes it one of the oldest colleges of technology in Germany, and one of the country’s oldest Universitäten, which in German today refers to institutes of higher education which cover the entire curriculum. The university is member of TU 9, a consortium of the nine leading German Institutes of Technology. 

    Also see Clinical Sensoring and Monitoring Research Group at TU Dresden