1. Dresden University of Technology

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    1. Mentioned In 109 Articles

    2. Depth-resolved birefringence imaging of collagen fiber organization in the human oral mucosa in vivo

      Depth-resolved birefringence imaging of collagen fiber organization in the human oral mucosa in vivo
      Stromal collagen organization has been identified as a potential prognostic indicator in a variety of cancers and other diseases accompanied by fibrosis. Changes in the connective tissue are increasingly considered for grading dysplasia and progress of oral squamous cell carcinoma, investigated mainly ex vivo by histopathology. In this study, polarization-sensitive optical coherence tomography (PS-OCT) with local phase retardation imaging is used for the first time to visualize depth-resolved (i.e ...
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    3. Quality Assessment of Tympanoplasty by Means of Endoscopic Optical Coherence Tomography

      Quality Assessment of Tympanoplasty by Means of Endoscopic Optical Coherence Tomography
      Introduction: The endoscopic optical coherence tomography (eOCT) allows the direct, contactless representation and evaluation of the morphology and oscillation behaviour of the tympanic membrane and adjoining tympanic cavity content. After further development of the measuring technology, the eOCT will be able to be used in vivo for the assessment of tympanoplasty results. Materials and Methods: The eOCT was applied to 10 patients after a tympanoplasty with an intact ossicular chain ...
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    4. Endoscopic Optical Coherence Tomography in Diagnostics of Otosclerosis

      Endoscopic Optical Coherence Tomography in Diagnostics of Otosclerosis
      Introduction: Endoscopic Optical Coherence Tomography (eOCT) enables both high-resolution contact-free 3D-imaging of the tympanic membrane and spatial and frequency-resolved oscillation measurement via Doppler-OCT. Thus it is possible to detect causes of conduction hearing loss. In case of otosclerosis, changes in oscillation amplitude at the umbo had been showed via Laser-Doppler-Vibrometry. Material and Methods: The eOCT system utilizes a swept source laser with a wave length around 1300nm. Field-of-view and working ...
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    5. Bleb Morphology After Mitomycin-C Augmented Trabeculectomy: Comparison Between Clinical Evaluation and Anterior Segment Optical Coherence Tomography

      Bleb Morphology After Mitomycin-C Augmented Trabeculectomy: Comparison Between Clinical Evaluation and Anterior Segment Optical Coherence Tomography
      Purpose: The main aim of this article was to study the longitudinal correlation between the clinical, morphological appearance of filtering blebs with anterior segment optical coherence tomography (AS-OCT) in the early postoperative period. Methods: Thirty eyes of 30 glaucoma patients scheduled for first-time trabeculectomy with 0.02% mitomycin-C were consecutively enrolled. The filtering blebs were evaluated clinically according to a grading system and with AS-OCT at day 1 and weeks ...
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    6. ACUTE RETINAL ISCHEMIA IN CENTRAL VERSUS BRANCH RETINAL ARTERY OCCLUSION Changes in Retinal Layers' Thickness on Spectral-Domain Optical Coherence Tomography in Different Grades of Retinal Ischemia

      ACUTE RETINAL ISCHEMIA IN CENTRAL VERSUS BRANCH RETINAL ARTERY OCCLUSION Changes in Retinal Layers' Thickness on Spectral-Domain Optical Coherence Tomography in Different Grades of Retinal Ischemia
      Purpose: To compare changes in thickness of separate retinal layers between acute central and branch retinal artery occlusion (RAO) regarding the severity grade of retinal ischemia using spectral-domain optical coherence tomography . Methods: Design : retrospective, observational casecontrol series. Setting: institutional. Patients: 114 patients with acute RAO. Examinations were conducted with spectral-domain optical coherence tomography at the first visit (baseline). Observations: RAO was categorized as branch (43 patients) or central RAO (71 ...
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    7. Endoscopic optical coherence tomography with wide field-of-view for the morphological and functional assessment of the human tympanic membrane

      Endoscopic optical coherence tomography with wide field-of-view for the morphological and functional assessment of the human tympanic membrane
      An endoscopic optical coherence tomography (OCT) system with a wide field-of-view of 8 mm is presented, which combines the image capability of endoscopic imaging at the middle ear with the advantages of functional OCT imaging, allowing a morphological and functional assessment of the human tympanic membrane. The endoscopic tube has a diameter of 3.5 mm and contains gradient-index optics for simultaneous forward-viewing OCT and video endoscopy. The endoscope allows ...
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    8. Visualization of interfacial adhesive defects at dental restorations with spectral domain and polarization sensitive optical coherence tomography

      Visualization of interfacial adhesive defects at dental restorations with spectral domain and polarization sensitive optical coherence tomography
      Restoration loss based on interfacial adhesive defects and associated caries at the restoration margin are the main causes for invasive replacement of dental restorations. Assessment of the interfacial quality based on clinical inspection and radiographic examination is often difficult and not reliable. In this work, we present spectral domain optical coherence tomography (SDOCT) and polarization sensitive optical coherence tomography (PSOCT) for the evaluation of tooth-composite bond failure. Imaging of two ...
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    9. Optical Coherence Tomography for NDE (Book Chapter)

      Optical Coherence Tomography for NDE (Book Chapter)
      Optical coherence tomography (OCT) is a noninvasive, high-resolution, interferometric imaging modality using near-infrared light to acquire cross sections and three-dimensional images of the subsurface microstructure of samples. Because of the rapid enhancement of OCT with respect to acquisition speed and axial resolution over the past years, OCT is becoming more and more attractive for applications in nondestructive testing and evaluation. In this chapter, a brief introduction to the technique and ...
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    10. A System for Clinical Use of Endoscopic Optical Coherence Tomography

      A System for Clinical Use of Endoscopic Optical Coherence Tomography
      Introduction: Optical Coherence Tomography (OCT) allows non-invasive high-resolution imaging of tissues. With a penetration depth of a few millimeters it's possible to image the tympanic membrane and the close-by part of the tympanum, e.g. for diagnostics of otitis media and middle ear effusion. In the field of in vivo examination there are difficulties in access to the human tympanic membrane due to the narrow and curved external ear ...
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    11. Multimodal imaging of lung tissue dynamics in mechanically ventilated rats with optical coherence tomography and intravital microscopy

      Multimodal imaging of lung tissue dynamics in mechanically ventilated rats with optical coherence tomography and intravital microscopy
      The understanding of alveolar mechanics is an essential step towards new and more protective ventilation strategies which are of dare need for the treatment of diseases of lung tissue and the airways. Such ailments become a major task for medical care and health care systems in modern industrial countries in the future. Besides the obvious importance as life-saving intervention, the mechanical strain and processes on the level of gas exchange ...
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    12. 4D optical coherence tomography for imaging aortic valve dynamics ex vivo

      4D optical coherence tomography for imaging aortic valve dynamics ex vivo
      The mechanical components of the heart, especially the valves, are enormously stressed during lifetime and undergo different pathophysiological tissue transformations, which affect cardiac output and in consequence living comfort of affected patients. Calcific aortic valve stenosis (AVS) is the most common valve disease in modern industrial countries but the pathogenesis and progression of this disease is still unknown. Therefore, animal models, especially mouse models, are a powerfull tool to investigate ...
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    13. In vivo imaging in the oral cavity by endoscopic optical coherence tomography

      In vivo imaging in the oral cavity by endoscopic optical coherence tomography
      The common way to diagnose hard and soft tissue irregularities in the oral cavity is initially the visual inspection by an experienced dentist followed by further medical examinations, such as radiological imaging and/or histopathological investigation. For the diagnosis of oral hard and soft tissues, the detection of early transformations is mostly hampered by poor visual access, low specificity of the diagnosis techniques, and/or limited feasibility of frequent screenings ...
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    14. Detection of carious lesions utilizing depolarization imaging by polarization sensitive optical coherence tomography

      Detection of carious lesions utilizing depolarization imaging by polarization sensitive optical coherence tomography
      As dental caries is one of the most common diseases, the early and noninvasive detection of carious lesions plays an important role in public health care. Optical coherence tomography (OCT) with its ability of depth-resolved, high-resolution, noninvasive, fast imaging has been previously recognized as a promising tool in dentistry. Additionally, polarization sensitive imaging provides quantitative measures on the birefringent tissue properties and can be utilized for imaging dental tissue, especially ...
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    15. In vivo imaging of human oral hard and soft tissues by polarization-sensitive optical coherence tomography

      In vivo imaging of human oral hard and soft tissues by polarization-sensitive optical coherence tomography
      Since optical coherence tomography (OCT) provides three-dimensional high-resolution images of biological tissue, the benefit of polarization contrast in the field of dentistry is highlighted in this study. Polarization-sensitive OCT (PS OCT) with phase-sensitive recording is used for imaging dental and mucosal tissues in the human oral cavity in vivo . An enhanced polarization contrast of oral structures is reached by analyzing the signals of the co- and crosspolarized channels of the ...
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    16. Advanced analysis of domain walls in Mg doped LiNbO3 crystals with high resolution OCT

      Advanced analysis of domain walls in Mg doped LiNbO3 crystals with high resolution OCT
      The structure of domain walls (DW) in ferroelectric media is of great interest as this material is used for frequency doublers and other applications. We show that the structure of the DWs can nicely be visualized by high resolution optical coherence tomography (OCT). While the high group refractive index of lithium niobate allows a resolution much better than 1 m, the large dispersion can blur the image and has to ...
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  2. About Dresden University of Technology

    Dresden University of Technology

    Dresden University of Technology (Technische Universität Dresde) is the largest institute of higher education in the city of Dresden, the largest university in Saxony and one of the 10 largest universities in Germany with 34,993 students as of 2006. The name Technische Universität Dresden has only been used since 1961; the history of the university, however, goes back nearly 200 years to 1828. This makes it one of the oldest colleges of technology in Germany, and one of the country’s oldest Universitäten, which in German today refers to institutes of higher education which cover the entire curriculum. The university is member of TU 9, a consortium of the nine leading German Institutes of Technology. 

    Also see Clinical Sensoring and Monitoring Research Group at TU Dresden