1. Dresden University of Technology

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    1. Mentioned In 115 Articles

    2. In Vivo Endoscopic Optical Coherence Tomography of the Healthy Human Oral Mucosa: Qualitative and Quantitative Image Analysis

      In Vivo Endoscopic Optical Coherence Tomography of the Healthy Human Oral Mucosa: Qualitative and Quantitative Image Analysis
      To date, there is still a lack of reliable imaging modalities to improve the quality of consultation, diagnostic and medical examinations of the oral mucosa in dentistry. Even though, optical technologies have become an important element for the detection and treatment of different diseases of soft tissue, for the case of oral screenings the evidence of the benefit in comparison to conventional histopathology is mostly still pending. One promising optical ...
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    3. Hyperreflectivity of Inner Retinal Layers as a Quantitative Parameter of Ischemic Damage in Acute Retinal Vein Occlusion (RVO): An Optical Coherence Tomography Study

      Hyperreflectivity of Inner Retinal Layers as a Quantitative Parameter of Ischemic Damage in Acute Retinal Vein Occlusion (RVO): An Optical Coherence Tomography Study
      Purpose: To investigate the reflectivity changes of inner retinal layers in acute retinal vein occlusion (RVO) on spectral-domain optical coherence tomography (SD-OCT) and to correlate these values with other known parameters of acute ischemic damage. Patients and Methods: In this retrospective and observational case series, 230 eyes from 115 patients with acute RVO (central or branch) were categorized as ischemic or non-ischemic depending on fluorescein angiography (FA) images at baseline ...
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    4. Endoscopic Optical Coherence Tomography for Evaluation of Success of Tympanoplasty

      Endoscopic Optical Coherence Tomography for Evaluation of Success of Tympanoplasty
      Objective: After tympanoplasty , it is often challenging to differentiate between different causes of a remaining air bone gap (ABG). Optical coherence tomography (OCT) offers a new approach for combined morphologic and functional measurements of the tympanic membrane and adjacent parts of the middle ear. Thus, it provides valuable diagnostic information in patients with a reduced sound transfer after middle ear surgery. Patient and intervention: A patient with history of tympanoplasty ...
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    5. Evaluation of middle ear reconstruction by endoscopic Optical Coherence Tomography

      Evaluation of middle ear reconstruction by endoscopic Optical Coherence Tomography
      Introduction Endoscopic Optical Coherence Tomography (eOCT) allows high-resolution 3-dimensional imaging of the tympanic membrane and the adjacent areas of the middle ear. Doppler-OCT enables oscillation measurement. Thus, the postoperative outcome of tympanoplasty can be evaluated. Material and Methods 5 Patients were examined after tympanoplasty using eOCT. The system utilizes a near infrared laser with a central wavelength of 1300 nm and a working range of 8 mm. The thickness of ...
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    6. Device and system for doppler optical coherence tomography (OCT) of the human middle ear

      Device and system for doppler optical coherence tomography (OCT) of the human middle ear
      A device for Doppler optical coherence tomography (Doppler OCT), preferably of the human middle ear, is proposed. The device has an endoscope unit for at least partial insertion into the auditory canal. A sound source, a sound receiver, and OCT optics are integrated in the endoscope unit.
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    7. Correlation between Lesion Progression and Depolarization Assessed by Polarization-Sensitive Optical Coherence Tomography

      Correlation between Lesion Progression and Depolarization Assessed by Polarization-Sensitive Optical Coherence Tomography
      The detection of early stages of caries is still one of the major challenges in preservative dentistry. Since it is known from polarized light microscopy (PLM) that intrinsic enamel birefringence is affected by demineralization, polarization-sensitive optical coherence tomography (PSOCT) could facilitate the noninvasive detection and assessment of early carious lesions. The present study aims to correlate enamel lesion progression and depolarization measurements based on PSOCT in an artificial demineralization model ...
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    8. Depth-resolved birefringence imaging of collagen fiber organization in the human oral mucosa in vivo

      Depth-resolved birefringence imaging of collagen fiber organization in the human oral mucosa in vivo
      Stromal collagen organization has been identified as a potential prognostic indicator in a variety of cancers and other diseases accompanied by fibrosis. Changes in the connective tissue are increasingly considered for grading dysplasia and progress of oral squamous cell carcinoma, investigated mainly ex vivo by histopathology. In this study, polarization-sensitive optical coherence tomography (PS-OCT) with local phase retardation imaging is used for the first time to visualize depth-resolved (i.e ...
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    9. Quality Assessment of Tympanoplasty by Means of Endoscopic Optical Coherence Tomography

      Quality Assessment of Tympanoplasty by Means of Endoscopic Optical Coherence Tomography
      Introduction: The endoscopic optical coherence tomography (eOCT) allows the direct, contactless representation and evaluation of the morphology and oscillation behaviour of the tympanic membrane and adjoining tympanic cavity content. After further development of the measuring technology, the eOCT will be able to be used in vivo for the assessment of tympanoplasty results. Materials and Methods: The eOCT was applied to 10 patients after a tympanoplasty with an intact ossicular chain ...
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    10. Endoscopic Optical Coherence Tomography in Diagnostics of Otosclerosis

      Endoscopic Optical Coherence Tomography in Diagnostics of Otosclerosis
      Introduction: Endoscopic Optical Coherence Tomography (eOCT) enables both high-resolution contact-free 3D-imaging of the tympanic membrane and spatial and frequency-resolved oscillation measurement via Doppler-OCT. Thus it is possible to detect causes of conduction hearing loss. In case of otosclerosis, changes in oscillation amplitude at the umbo had been showed via Laser-Doppler-Vibrometry. Material and Methods: The eOCT system utilizes a swept source laser with a wave length around 1300nm. Field-of-view and working ...
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    11. Bleb Morphology After Mitomycin-C Augmented Trabeculectomy: Comparison Between Clinical Evaluation and Anterior Segment Optical Coherence Tomography

      Bleb Morphology After Mitomycin-C Augmented Trabeculectomy: Comparison Between Clinical Evaluation and Anterior Segment Optical Coherence Tomography
      Purpose: The main aim of this article was to study the longitudinal correlation between the clinical, morphological appearance of filtering blebs with anterior segment optical coherence tomography (AS-OCT) in the early postoperative period. Methods: Thirty eyes of 30 glaucoma patients scheduled for first-time trabeculectomy with 0.02% mitomycin-C were consecutively enrolled. The filtering blebs were evaluated clinically according to a grading system and with AS-OCT at day 1 and weeks ...
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    12. ACUTE RETINAL ISCHEMIA IN CENTRAL VERSUS BRANCH RETINAL ARTERY OCCLUSION Changes in Retinal Layers' Thickness on Spectral-Domain Optical Coherence Tomography in Different Grades of Retinal Ischemia

      ACUTE RETINAL ISCHEMIA IN CENTRAL VERSUS BRANCH RETINAL ARTERY OCCLUSION Changes in Retinal Layers' Thickness on Spectral-Domain Optical Coherence Tomography in Different Grades of Retinal Ischemia
      Purpose: To compare changes in thickness of separate retinal layers between acute central and branch retinal artery occlusion (RAO) regarding the severity grade of retinal ischemia using spectral-domain optical coherence tomography . Methods: Design : retrospective, observational casecontrol series. Setting: institutional. Patients: 114 patients with acute RAO. Examinations were conducted with spectral-domain optical coherence tomography at the first visit (baseline). Observations: RAO was categorized as branch (43 patients) or central RAO (71 ...
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    13. Endoscopic optical coherence tomography with wide field-of-view for the morphological and functional assessment of the human tympanic membrane

      Endoscopic optical coherence tomography with wide field-of-view for the morphological and functional assessment of the human tympanic membrane
      An endoscopic optical coherence tomography (OCT) system with a wide field-of-view of 8 mm is presented, which combines the image capability of endoscopic imaging at the middle ear with the advantages of functional OCT imaging, allowing a morphological and functional assessment of the human tympanic membrane. The endoscopic tube has a diameter of 3.5 mm and contains gradient-index optics for simultaneous forward-viewing OCT and video endoscopy. The endoscope allows ...
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    14. Visualization of interfacial adhesive defects at dental restorations with spectral domain and polarization sensitive optical coherence tomography

      Visualization of interfacial adhesive defects at dental restorations with spectral domain and polarization sensitive optical coherence tomography
      Restoration loss based on interfacial adhesive defects and associated caries at the restoration margin are the main causes for invasive replacement of dental restorations. Assessment of the interfacial quality based on clinical inspection and radiographic examination is often difficult and not reliable. In this work, we present spectral domain optical coherence tomography (SDOCT) and polarization sensitive optical coherence tomography (PSOCT) for the evaluation of tooth-composite bond failure. Imaging of two ...
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    15. Optical Coherence Tomography for NDE (Book Chapter)

      Optical Coherence Tomography for NDE (Book Chapter)
      Optical coherence tomography (OCT) is a noninvasive, high-resolution, interferometric imaging modality using near-infrared light to acquire cross sections and three-dimensional images of the subsurface microstructure of samples. Because of the rapid enhancement of OCT with respect to acquisition speed and axial resolution over the past years, OCT is becoming more and more attractive for applications in nondestructive testing and evaluation. In this chapter, a brief introduction to the technique and ...
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    16. A System for Clinical Use of Endoscopic Optical Coherence Tomography

      A System for Clinical Use of Endoscopic Optical Coherence Tomography
      Introduction: Optical Coherence Tomography (OCT) allows non-invasive high-resolution imaging of tissues. With a penetration depth of a few millimeters it's possible to image the tympanic membrane and the close-by part of the tympanum, e.g. for diagnostics of otitis media and middle ear effusion. In the field of in vivo examination there are difficulties in access to the human tympanic membrane due to the narrow and curved external ear ...
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  2. About Dresden University of Technology

    Dresden University of Technology

    Dresden University of Technology (Technische Universität Dresde) is the largest institute of higher education in the city of Dresden, the largest university in Saxony and one of the 10 largest universities in Germany with 34,993 students as of 2006. The name Technische Universität Dresden has only been used since 1961; the history of the university, however, goes back nearly 200 years to 1828. This makes it one of the oldest colleges of technology in Germany, and one of the country’s oldest Universitäten, which in German today refers to institutes of higher education which cover the entire curriculum. The university is member of TU 9, a consortium of the nine leading German Institutes of Technology. 

    Also see Clinical Sensoring and Monitoring Research Group at TU Dresden