1. Dresden University of Technology

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    1. Mentioned In 101 Articles

    2. A System for Clinical Use of Endoscopic Optical Coherence Tomography

      A System for Clinical Use of Endoscopic Optical Coherence Tomography
      Introduction: Optical Coherence Tomography (OCT) allows non-invasive high-resolution imaging of tissues. With a penetration depth of a few millimeters it's possible to image the tympanic membrane and the close-by part of the tympanum, e.g. for diagnostics of otitis media and middle ear effusion. In the field of in vivo examination there are difficulties in access to the human tympanic membrane due to the narrow and curved external ear ...
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    3. Multimodal imaging of lung tissue dynamics in mechanically ventilated rats with optical coherence tomography and intravital microscopy

      Multimodal imaging of lung tissue dynamics in mechanically ventilated rats with optical coherence tomography and intravital microscopy
      The understanding of alveolar mechanics is an essential step towards new and more protective ventilation strategies which are of dare need for the treatment of diseases of lung tissue and the airways. Such ailments become a major task for medical care and health care systems in modern industrial countries in the future. Besides the obvious importance as life-saving intervention, the mechanical strain and processes on the level of gas exchange ...
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    4. 4D optical coherence tomography for imaging aortic valve dynamics ex vivo

      4D optical coherence tomography for imaging aortic valve dynamics ex vivo
      The mechanical components of the heart, especially the valves, are enormously stressed during lifetime and undergo different pathophysiological tissue transformations, which affect cardiac output and in consequence living comfort of affected patients. Calcific aortic valve stenosis (AVS) is the most common valve disease in modern industrial countries but the pathogenesis and progression of this disease is still unknown. Therefore, animal models, especially mouse models, are a powerfull tool to investigate ...
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    5. In vivo imaging in the oral cavity by endoscopic optical coherence tomography

      In vivo imaging in the oral cavity by endoscopic optical coherence tomography
      The common way to diagnose hard and soft tissue irregularities in the oral cavity is initially the visual inspection by an experienced dentist followed by further medical examinations, such as radiological imaging and/or histopathological investigation. For the diagnosis of oral hard and soft tissues, the detection of early transformations is mostly hampered by poor visual access, low specificity of the diagnosis techniques, and/or limited feasibility of frequent screenings ...
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    6. Detection of carious lesions utilizing depolarization imaging by polarization sensitive optical coherence tomography

      Detection of carious lesions utilizing depolarization imaging by polarization sensitive optical coherence tomography
      As dental caries is one of the most common diseases, the early and noninvasive detection of carious lesions plays an important role in public health care. Optical coherence tomography (OCT) with its ability of depth-resolved, high-resolution, noninvasive, fast imaging has been previously recognized as a promising tool in dentistry. Additionally, polarization sensitive imaging provides quantitative measures on the birefringent tissue properties and can be utilized for imaging dental tissue, especially ...
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    7. In vivo imaging of human oral hard and soft tissues by polarization-sensitive optical coherence tomography

      In vivo imaging of human oral hard and soft tissues by polarization-sensitive optical coherence tomography
      Since optical coherence tomography (OCT) provides three-dimensional high-resolution images of biological tissue, the benefit of polarization contrast in the field of dentistry is highlighted in this study. Polarization-sensitive OCT (PS OCT) with phase-sensitive recording is used for imaging dental and mucosal tissues in the human oral cavity in vivo . An enhanced polarization contrast of oral structures is reached by analyzing the signals of the co- and crosspolarized channels of the ...
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    8. Advanced analysis of domain walls in Mg doped LiNbO3 crystals with high resolution OCT

      Advanced analysis of domain walls in Mg doped LiNbO3 crystals with high resolution OCT
      The structure of domain walls (DW) in ferroelectric media is of great interest as this material is used for frequency doublers and other applications. We show that the structure of the DWs can nicely be visualized by high resolution optical coherence tomography (OCT). While the high group refractive index of lithium niobate allows a resolution much better than 1 m, the large dispersion can blur the image and has to ...
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    9. Improved Imaging of Magnetically Labeled Cells Using Rotational Magnetomotive Optical Coherence Tomography

      Improved Imaging of Magnetically Labeled Cells Using Rotational Magnetomotive Optical Coherence Tomography
      Abstract In this paper, we present a reliable and robust method for magnetomotive optical coherence tomography (MM-OCT) imaging of single cells labeled with iron oxide particles. This method employs modulated longitudinal and transverse magnetic fields to evoke alignment and rotation of anisotropic magnetic structures in the sample volume. Experimental evidence suggests that magnetic particles assemble themselves in elongated chains when exposed to a permanent magnetic field. Magnetomotion in the intracellular ...
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    10. Flow Measurement by Lateral Resonant Doppler Optical Coherence Tomography in the Spectral Domain

      Flow Measurement by Lateral Resonant Doppler Optical Coherence Tomography in the Spectral Domain
      In spectral domain optical coherence tomography (SD-OCT), any transverse motion component of a detected obliquely moving sample results in a nonlinear relationship between the Doppler phase shift and the axial sample velocity restricting phase-resolved Doppler OCT (PR-DOCT). The size of the deviation from the linear relation depends on the amount of the transverse velocity component, given by the Doppler angle, and the height of the absolute sample velocity. Especially for ...
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    11. Optical Coherence Tomography (OCT) for Time-Resolved Imaging of Alveolar Dynamics in Mechanically Ventilated Rats

      Optical Coherence Tomography (OCT) for Time-Resolved Imaging of Alveolar Dynamics in Mechanically Ventilated Rats
      Though artificial ventilation is an essential life-saving treatment, the mechanical behavior of lung tissue at the alveolar level is still unknown. Therefore, we need to understand the tissue response during artificial ventilation at this microscale in order to develop new and more protective ventilation methods. Optical coherence tomography (OCT) combined with intravital microscopy (IVM) is a promising tool for visualizing lung tissue dynamics with a high spatial and temporal resolution ...
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    12. Enamel Thickness before and after Orthodontic Treatment Analysed in Optical Coherence Tomography

      Enamel Thickness before and after Orthodontic Treatment Analysed in Optical Coherence Tomography
      Despite the continuous development of materials and techniques of adhesive bonding, the basic procedure remains relatively constant. The technique is based on three components: etching substance, adhesive system, and composite material. The use of etchants during bonding orthodontic brackets carries the risk of damage to the enamel. Therefore, the article examines the effect of the manner of enamel etching on its thickness before and after orthodontic treatment. The study was ...
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    13. Impact of a detector dead time in phase-resolved Doppler analysis using spectral domain optical coherence tomography

      Impact of a detector dead time in phase-resolved Doppler analysis using spectral domain optical coherence tomography
      For any oblique sample movement containing a transverse velocity component, the commonly used linear relationship between the phase shift and the axial velocity component is erroneous for spectrometer-based optical coherence tomography (spectral domain OCT, SD-OCT). We recently proposed a new Doppler model that assumes a continuous integration of the photocurrent. In this research, we extend the model for detectors with a shutter control by taking detector dead time into account ...
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    14. Doppler optical coherence tomography as a promising tool for detecting fluid in the human middle ear

      Doppler optical coherence tomography as a promising tool for detecting fluid in the human middle ear
      The treatment of otitis media requires classifying the effusion in the tympanic cavity for choosing appropriate therapeutic strategies. Otoscopic examination of the middle ear depends on the expertise of the physician and is often hampered in case of inflammatory alterations of the tympanic membrane. In otologic research, optical coherence tomography is an innovative non-invasive imaging technique utilized for visualizing the tympanic membrane. This ex vivo study presents the possibility of ...
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    15. PhD Student Position in Optical Coherence Tomography in Biomedical Research at the TU Dresden, Germany

      PhD Student Position in Optical Coherence Tomography in Biomedical Research at the TU Dresden, Germany
      Within the scope of the junior research group Optical Technologies in Medicine, new methods in optical imaging are transferred into medical and clinical application. The research is focused on optical coherence tomography and other optical methods for the diagnosis of different diseases. The PHD student will join a group of medical scientists, engineers, information and natural scientists. Requirements You hold, or to be about to receive before starting the contract ...
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    16. Improved non-invasive Optical Coherence Tomography detection of different engineered nanoparticles in food-mimicking matrices

      Improved non-invasive Optical Coherence Tomography detection of different engineered nanoparticles in food-mimicking matrices
      Food industry and regulators require fast and reliable analytical methods for quality control. This especially counts for the detection of engineered nanomaterials (ENMs) in food products. Respective EU regulation is in force, but the development of appropriate methods is still underway. This paper updates the scope of Optical Coherence Tomography (OCT) for ENM/food matrix analysis. A range of nanomaterials and composites Au@SiO 2 , Ag, Ag@SiO 2 and ...
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  2. About Dresden University of Technology

    Dresden University of Technology

    Dresden University of Technology (Technische Universität Dresde) is the largest institute of higher education in the city of Dresden, the largest university in Saxony and one of the 10 largest universities in Germany with 34,993 students as of 2006. The name Technische Universität Dresden has only been used since 1961; the history of the university, however, goes back nearly 200 years to 1828. This makes it one of the oldest colleges of technology in Germany, and one of the country’s oldest Universitäten, which in German today refers to institutes of higher education which cover the entire curriculum. The university is member of TU 9, a consortium of the nine leading German Institutes of Technology. 

    Also see Clinical Sensoring and Monitoring Research Group at TU Dresden