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    1. Mentioned In 56 Articles

    3. Unsupervised despeckling of optical coherence tomography images by combining cross-scale CNN with an intra-patch and inter-patch based transformer

      Explore Optica Publishing Group
      Unsupervised despeckling of optical coherence tomography images by combining cross-scale CNN with an intra-patch and inter-patch based transformer
      ...als.gov (Identifier: NCT00734487) and approved by the institutional review boards of the 4A2A SD-OCT clinics (Devers Eye Institute, Duke Eye Center, Emory Eye Center, and National Eye Institute) [45]. With adherence to t...
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      Mentions: National Institutes of Health Devers Eye Institute

    5. Legacy Emanuel Hospital and Health Center Receives NIH Grant for Advancing OCT evaluation to reveal early-stage changes in glaucoma

      Explore Optical Coherence Tomography News Ophthalmology , Funding
      Legacy Emanuel Hospital and Health Center Receives NIH Grant for Advancing OCT evaluation to reveal early-stage changes in glaucoma
      Legacy Emanuel Hospital and Health Center Receives a 2021 NIH Grant for $683,321 for Advancing OCT evaluation to reveal early-stage changes in glaucoma. The principal investigator is Brad Fortune. Below is a summary of the proposed work. Currently, diagnosis of glaucoma and patient management decisions are often informed by thinning of the optic nerve head (ONH) neuro-retinal rim, peripapillary retinal nerve fiber layer (RNFL), and macular inner retinal layers ...
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      Mentions: National Institutes of Health Devers Eye Institute

    6. A high-accuracy and high-efficiency digital volume correlation method to characterize in-vivo optic nerve head biomechanics from optical coherence tomography

      Explore bioRxiv.org Ophthalmology
      A high-accuracy and high-efficiency digital volume correlation method to characterize in-vivo optic nerve head biomechanics from optical coherence tomography
      In-vivo optic nerve head (ONH) biomechanics characterization is emerging as a promising way to study eye physiology and pathology. We propose a high-accuracy and high-efficiency digital volume correlation (DVC) method for the purpose of characterizing the in-vivo ONH deformation from volumes acquired by optical coherence tomography (OCT). Using a combination of synthetic tests and analysis of OCTs from monkey ONHs subjected to acute and chronically elevated intraocular pressure, we demonstrate ...
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      Mentions: University of Pittsburgh Devers Eye Institute

    9. Histologic validation of optical coherence tomography-based three-dimensional morphometric measurements of the human optic nerve head: Methodology and preliminary results

      Explore ScienceDirect Ophthalmology
      Histologic validation of optical coherence tomography-based three-dimensional morphometric measurements of the human optic nerve head: Methodology and preliminary results
      Purpose To compare the three-dimensional (3D) morphology of the deep load-bearing structures of the human optic nerve head (ONH) as revealed in vivo by spectral domain optical coherence tomography (SDOCT) with ex vivo quantitative 3D histology. Methods SDOCT imaging of the ONH was performed in six eyes from three brain-dead organ donors on life-support equipment awaiting organ procurement (in vivo conditions). Following organ procurement (ex vivo conditions), the eyes were ...
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      Mentions: University of Alabama Devers Eye Institute

    10. Legacy Emanuel Hospital and Health Center Receives NIH Grant for Advancing OCT Evolution to Reveal Early-Stage Changes in Glaucoma

      Explore Optical Coherence Tomography News Ophthalmology , Funding
      Legacy Emanuel Hospital and Health Center Receives NIH Grant for Advancing OCT Evolution to Reveal Early-Stage Changes in Glaucoma
      Legacy Emanuel Hospital and Health Center Receives a 2020 NIH Grant for $543,351 for Advancing OCT Evolution to Reveal Early-Stage Chalnges in Glaucoma. The principal investigator is Brad Fortune. Below is a summary of the proposed work. Currently, diagnosis of glaucoma and patient management decisions are often informed by thinning of the optic nerve head (ONH) neuro-retinal rim, peripapillary retinal nerve fiber layer (RNFL), and macular inner retinal layers ...
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      Mentions: National Institutes of Health Devers Eye Institute

    12. OCT Structural Abnormality Detection in Glaucoma using Topographically Correspondent Rim and Retinal Nerve Fiber Layer Criteria

      Explore American Journal of Ophthalmology Ophthalmology
      OCT Structural Abnormality Detection in Glaucoma using Topographically Correspondent Rim and Retinal Nerve Fiber Layer Criteria
      Purpose To evaluate the ability of topographically correspondent (TC) minimum rim width (MRW) and peripapillary retinal nerve fiber layer thickness (pRNFLT) criteria to detect optical coherence tomography (OCT) structural abnormality in glaucoma (GL) and glaucoma suspect (GLS) eyes. Design Retrospective cross-sectional study. Methods 196 GL, 150 GLS eyes and 303 Heathy eyes underwent PRNFL and 24 radial optic nerve head OCT imaging and manual correction of the internal limiting membrane ...
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      Mentions: Devers Eye Institute

    13. Effect of Trabeculectomy on Optical Coherence Tomography (OCT) Measurements of the Optic Nerve Head Neuroretinal Rim Tissue

      Explore ophthalmologyglaucoma.org Ophthalmology
      Effect of Trabeculectomy on Optical Coherence Tomography (OCT) Measurements of the Optic Nerve Head Neuroretinal Rim Tissue
      Purpose Ophthalmologists commonly perform glaucoma surgery to treat progressive glaucoma. Few studies have examined the stability of OCT neuroretinal rim parameters after glaucoma surgery for ongoing detection of glaucoma progression. Design Longitudinal cohort study. Participants 20 eyes (16 subjects) with primary open angle glaucoma who had undergone a trabeculectomy. Methods We calculated the change in OCT parameters (minimum rim area (MRA), minimum rim width (MRW), Bruchs membrane opening (BMO) area ...
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      Mentions: Devers Eye Institute

    14. OCT-Detected Optic Nerve Head Neural Canal Direction, Obliqueness and Minimum Cross-Sectional Area in Healthy Eyes

      Explore ScienceDirect Ophthalmology
      OCT-Detected Optic Nerve Head Neural Canal Direction, Obliqueness and Minimum Cross-Sectional Area in Healthy Eyes
      Purpose To assess anterior scleral canal opening (ASCO) offset relative to Bruchs membrane opening (BMO) (ASCO/BMO offset) so as to determine neural canal direction, obliqueness, and minimum cross-sectional area (NCMCA) in 362 healthy eyes. Design Cross-sectional study Methods After OCT optic nerve head (ONH) and retinal nerve fiber layer thickness (RNFLT) imaging, BMO and ASCO were manually segmented and planes, centroids, size and shape were calculated. Neural canal direction ...
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      Mentions: Johns Hopkins University Mount Sinai School of Medicine University of Alabama

    15. Optical Coherence Tomography Segmentation Errors of the Retinal Nerve Fiber Layer Persist Over Time

      Explore LWW Online Ophthalmology
      Optical Coherence Tomography Segmentation Errors of the Retinal Nerve Fiber Layer Persist Over Time
      Prcis: There are errors in automated segmentation of the retinal nerve fiber layer in glaucoma suspects or patients with mild glaucoma that appear to persist over time; however, automated segmentation has greater repeatability than manual segmentation. Purpose: To identify whether optical coherence tomography (OCT) segmentation errors in retinal nerve fiber layer (RNFL) thickness measurements persist longitudinally. Methods: This was a cohort study. We used spectral domain OCT (Spectralis, Heidelberg Engineering ...
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      Mentions: Devers Eye Institute

    16. Emanuel Hospital and Health Center Receives NIH Grant for IOP-Related Force and Failure in the Optical Nerve Head

      Explore Optical Coherence Tomography News Ophthalmology , Funding
      Emanuel Hospital and Health Center Receives NIH Grant for IOP-Related Force and Failure in the Optical Nerve Head
      Emanuel Hospital and Health Center Receives a 2019 NIH Grant for $579,552 for IOP-Related Force and Failure in the Optical Nerve Head. The principal investigator is Claude Burgoyne. The program began in 2018 and ends in 2021. Below is a summary of the proposed work. In the previous project period we completed our 3D histomorphometric characterization of connective tissue deformation and remodeling in early through end-stage monkey experimental glaucoma ...
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      Mentions: National Institutes of Health Devers Eye Institute
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    Devers Eye Institute is a comprehensive medical eye center dedicated to offering excellence in all aspects of eye care. We are a private, non-profit, clinical and research institute—one of only a handful in the United States.

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