1. Desmond C. Adler

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    1. Mentioned In 38 Articles

    2. Optical buffer-based apparatus for increasing light source repetition rate

      Optical buffer-based apparatus for increasing light source repetition rate
      In one embodiment, the invention relates to an apparatus for increasing the repetition rate in a light source. The apparatus includes a first optical coupler comprising a first arm, a second arm and a third arm; a first mirror in optical communication with the second arm of the first optical coupler; and a first optical delay line having a first end in optical communication with the third arm of the ...
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    3. Multimodal imaging system, apparatus, and methods

      Multimodal imaging system, apparatus, and methods
      In part, the invention relates to an image data collection system. The system can include an interferometer having a reference arm that includes a first optical fiber of length of L1 and a sample arm that includes a second optical fiber of length of L2 and a first rotary coupler configured to interface with an optical tomography imaging probe, wherein the rotary coupler is in optical communication with the sample ...
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    4. Optical coherence tomography control systems and methods

      Optical coherence tomography control systems and methods
      In part, the invention relates to methods, devices, and systems suitable for controlling a light source. The light source is configured for use in a data collection system such as an optical coherence tomography system. The light source can be controlled with a drive waveform. Linearizing and symmetrizing parameters of the light source such as forward and backward scan durations is achieved using a suitable drive waveform. Phase, amplitude, and ...
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    5. Method for identifying malignancies in barrett's esophagus using white light endoscopy

      Method for identifying malignancies in barrett's esophagus using white light endoscopy
      A method is described for computing a statistically significant difference between dysplasia and Barrett's esophagus (both with and without inflammatory component) using a discriminate function with diffuse reflectance measurements performed at a minimum of four different wavelengths of 485, 513, 598, and 629 nm. The discriminate function found depends both on local blood fraction volume T.sub.HB and oxygenation SO.sub.2. A pull-back approach of spectral data ...
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    6. Optical buffering methods, apparatus, and systems for increasing the repetition rate of tunable light sources

      Optical buffering methods, apparatus, and systems for increasing the repetition rate of tunable light sources
      In one embodiment, the invention relates to an apparatus for increasing the repetition rate in a light source. The apparatus includes a first optical coupler comprising a first arm, a second arm and a third arm; a first mirror in optical communication with the second arm of the first optical coupler; and a first optical delay line having a first end in optical communication with the third arm of the ...
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    7. Vascular Data Processing And Image Registration Systems, Methods, And Apparatuses

      Vascular Data Processing And Image Registration Systems, Methods, And Apparatuses
      In part, the invention relates to processing, tracking and registering angiography images and elements in such images relative to images from an intravascular imaging modality such as, for example, optical coherence tomography (OCT). Registration between such imaging modalities is facilitated by tracking of a marker of the intravascular imaging probe performed on the angiography images obtained during a pullback. Further, detecting and tracking vessel centerlines is used to perform a ...
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    8. Optical Coherence Tomography Control Systems And Methods

      Optical Coherence Tomography Control Systems And Methods
      In part, the invention relates to methods, devices, and systems suitable for controlling a light source (7). The light source is configured for use in a data collection system such as an optical coherence tomography system (5). The light source (7) can be controlled with a drive waveform (10, 22, 55, 70). Linearizing and symmetrizing parameters of the light source (7) such as forward (35, 60, 75) and backward (33 ...
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    9. Methods, systems, and devices for timing control in electromagnetic radiation sources

      Methods, systems, and devices for timing control in electromagnetic radiation sources
      In one embodiment, the invention relates to systems, methods and devices for improving the operation of an electromagnetic radiation source or component thereof. In one embodiment, the source is a laser source. A Fourier domain mode locked laser can be used in various embodiments. The sources described herein can be used in an optical coherence tomography (OCT) system such as a frequency domain OCT system. In one embodiment, laser coherence ...
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    10. Miniature optical elements for fiber-optic beam shaping

      Miniature optical elements for fiber-optic beam shaping
      In part, the invention relates to optical caps having at least one lensed surface configured to redirect and focus light outside of the cap. The cap is placed over an optical fiber. Optical radiation travels through the fiber and interacts with the optical surface or optical surfaces of the cap, resulting in a beam that is either focused at a distance outside of the cap or substantially collimated. The optical ...
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    11. Fourier domain mode locking: method and apparatus for control and improved performance

      Fourier domain mode locking: method and apparatus for control and improved performance
      A control system for improving and stabilizing Fourier domain mode locking (FDML) operation. The control system may also provide regulation of FDML operational parameters such as filter tuning, laser gain, polarization, polarization chromaticity, elliptical polarization retardance, and/or dispersion. The control system may be located internal to or external from the FDML laser cavity.
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    12. Extended coherence length megahertz FDML and its application for anterior segment imaging

      Extended coherence length megahertz FDML and its application for anterior segment imaging
      We present a 1300 nm Fourier domain mode locked (FDML) laser for optical coherence tomography (OCT) that combines both, a high 1.6 MHz wavelength sweep rate and an ultra-long instantaneous coherence length for rapid volumetric deep field imaging. By reducing the dispersion in the fiber delay line of the FDML laser, the instantaneous coherence length and hence the available imaging range is approximately quadrupled compared to previously published MHz-FDML ...
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    13. Bench-to-bedside success: intravascular optical coherence tomography

      Bench-to-bedside success: intravascular optical coherence tomography
      After more than 20 years of academic research and industrial development, optical coherence tomography has found a new home in the interventional cardiology suite. If one were to ask a physician to describe an ideal medical imaging technology, the resulting wish list might include high resolution, high sensitivity, and rapid acquisition speeds, all delivered at low cost with minimal risk to the patient in a platform that is simple and ...
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    14. Structural markers observed with endoscopic 3-dimensional optical coherence tomography correlating with Barrett's esophagus radiofrequency ablation treatment response (with videos)

      Structural markers observed with endoscopic 3-dimensional optical coherence tomography correlating with Barrett's esophagus radiofrequency ablation treatment response (with videos)
      ...Affiliations + Veterans Affairs Boston Healthcare System, Boston, MA + Harvard Medical School, Boston, MA , * Desmond C. Adler, PhD Affiliations + LightLab Imaging Inc, St. Jude Medical Inc, Westford, Massachusetts, USA ...
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    15. Comparison of Tissue Architectural Changes between Radiofrequency Ablation and Cryospray Ablation in Barrett’s Esophagus Using Endoscopic Three-Dimensional Optical Coherence Tomography

      Comparison of Tissue Architectural Changes between Radiofrequency Ablation and Cryospray Ablation in Barrett’s Esophagus Using Endoscopic Three-Dimensional Optical Coherence Tomography
      Two main nonsurgical endoscopic approaches for ablating dysplastic and early cancer lesions in the esophagus have gained popularity, namely, radiofrequency ablation (RFA) and cryospray ablation (CSA). We report a uniquely suited endoscopic and near-microscopic imaging modality, three-dimensional (3D) optical coherence tomography (OCT), to assess and compare the esophagus immediately after RFA and CSA. The maximum depths of architectural changes were measured and compared between the two treatment groups. RFA was ...
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    16. Cervical inlet patch-optical coherence tomography imaging and clinical significance

      Cervical inlet patch-optical coherence tomography imaging and clinical significance
      AIM: To demonstrate the feasibility of optical coherence tomography (OCT) imaging in differentiating cervical inlet patch (CIP) from normal esophagus, Barrett’s esophagus (BE), normal stomach and duodenum. METHODS: This study was conducted at the Veterans Affairs Boston Healthcare System (VABHS). Patients undergoing standard esophagogastroduodenoscopy at VABHS, including one patient with CIP, one representative patient with BE and three representative normal subjects were included. White light video endoscopy was performed ...
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    17. 1-15 of 38 1 2 3 »
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  2. About Desmond C. Adler

    Desmond C. Adler

    Desmond C. Adler is a project manager and senior researcher at LightLab Imaging, Inc. Prior to this, he was a PhD student in the Lasers and Medical Imaging Group of Professor James Fujimoto at MIT. Dr. Adler specializes in ultrahigh-speed OCT system design, swept laser development, and clinical applications of OCT such as cardiology and gastroenterology.