1. Delft University of Technology

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    1. Mentioned In 48 Articles

    2. Optimization-based adaptive optics for optical coherence tomography (Thesis)

      Optimization-based adaptive optics for optical coherence tomography (Thesis)
      Optical coherence tomography (OCT) is a technique for non-invasive imaging based on low coherence interferometry. Its main application is found in ophthalmology, where it is used for 3D in vivo imaging of the cornea and the retina. OCT has evolved over the past decade as one of the most important ancillary tests in ophthalmic practice, providing great diagnostic value for disease screening and monitoring. In retinal OCT imaging, the lateral ...
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    3. Analysis and compensation for the effect of the catheter position on image intensities in intravascular optical coherence tomography

      Analysis and compensation for the effect of the catheter position on image intensities in intravascular optical coherence tomography
      Intravascular optical coherence tomography (IVOCT) is an imaging technique that is used to analyze the underlying cause of cardiovascular disease. Because a catheter is used during imaging, the intensities can be affected by the catheter position. This work aims to analyze the effect of the catheter position on IVOCT image intensities and to propose a compensation method to minimize this effect in order to improve the visualization and the automatic ...
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    4. Spatially-resolved in-situ quantification of biofouling using optical coherence tomography (OCT) and 3D image analysis in a spacer filled channel

      Spatially-resolved in-situ quantification of biofouling using optical coherence tomography (OCT) and 3D image analysis in a spacer filled channel
      The use of optical coherence tomography (OCT) to investigate biomass in membrane systems has increased with time. OCT is able to characterize the biomass in-situ and non-destructively. In this study, a novel approach to process three-dimensional (3D) OCT scans is proposed. The approach allows obtaining spatially-resolved detailed structural biomass information. The 3D biomass reconstruction enables analysis of the biomass only, obtained by subtracting the time zero scan to all images ...
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    5. Optical coherence tomography attenuation imaging for lipid core detection: an ex-vivo validation study

      Optical coherence tomography attenuation imaging for lipid core detection: an ex-vivo validation study
      Lipid-core atherosclerotic plaques are associated with disease progression, procedural complications, and cardiac events. Coronary plaque lipid can be quantified in optical coherence tomography (OCT) pullbacks by measurement of lipid arcs and lipid lengths; parameters frequently used in clinical research, but labor intensive and subjective to analyse. In this study, we investigated the ability of quantitative attenuation, derived from intravascular OCT, to detect plaque lipid. Lipid cores are associated with a ...
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    6. A wafer-level miniaturized Michelson interferometer on glass substrate for Optical Coherence Tomography applications

      A wafer-level miniaturized Michelson interferometer on glass substrate for Optical Coherence Tomography applications
      The wafer-level fabrication of a Michelson interferometer using optical MEMS technologies is presented. The intended application is in Optical Coherence Tomography (OCT). The micro fabrication involves two steps: the 45 saw dicing of glass substrate and the subsequent deposition of a dielectric multilayer and metallic layers to obtain a beam splitter and waveguide micro mirrors, respectively. The Michelson interferometer was designed for use in the near-infrared range of 800900 nm ...
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    7. Transmission optical coherence tomography based measurement of optical material properties

      Transmission optical coherence tomography based measurement of optical material properties
      We present transmission optical coherence tomography (transmission OCT) as a versatile tool to measure optical material properties of turbid media. The transmission OCT signal is described in detail and it is demonstrated how the group refractive index ( n g ), group velocity dispersion (GVD) and optical attenuation can be determined from this signal. We experimentally validate the refractive index properties of glasses, liquids and glucose water solutions in terms of n ...
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    8. Model-based sensor-less wavefront aberration correction in optical coherence tomography

      Model-based sensor-less wavefront aberration correction in optical coherence tomography
      Several sensor-less wavefront aberration correction methods that correct nonlinear wavefront aberrations by maximizing the optical coherence tomography (OCT) signal are tested on an OCT setup. A conventional coordinate search method is compared to two model-based optimization methods. The first model-based method takes advantage of the well-known optimization algorithm (NEWUOA) and utilizes a quadratic model. The second model-based method (DONE) is new and utilizes a random multidimensional Fourier-basis expansion. The model-based ...
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    9. Feature Of The Week 12/06/2015: Heartbeat Optical Coherence Tomography

      Feature Of The Week 12/06/2015: Heartbeat Optical Coherence Tomography
      Intravascular optical coherence tomography (IV-OCT) has gained widespread use over the past few years, offering highly detailed images of the coronary artery pathologies and interventions. In contrast to the cross-sectional view, longitudinal sections and three-dimensional (3D) renderings are affected by cardiac motion artifacts and undersampling, complicating interpretation and measurements. We developed Heartbeat OCT, a new OCT method that overcomes these issues. This study aims to demonstrate in vivo Heartbeat OCT ...
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    10. An Evaluation of Silicon Carbide Based Bimorph Actuators for Optical Coherence Tomography Applications

      An Evaluation of Silicon Carbide Based Bimorph Actuators for Optical Coherence Tomography Applications
      Optical coherence tomography (OCT) probes rely on MEMS micro-scanners to provide fast and reproducible scans covering as much area as possible. A popular choice of actuators employed in this role are electrothermal bimorph actuators. They comprise of two layers of different materials which are rigidly joined together. Differential expansion under heating causes the bimorph to deflect. Polycrystalline silicon carbide has been proposed to replace polysilicon as a multi-purpose material in ...
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    11. Heartbeat OCT: in vivo intravascular megahertz-optical coherence tomography

      Heartbeat OCT: in vivo intravascular megahertz-optical coherence tomography
      Cardiac motion artifacts, non-uniform rotational distortion and undersampling affect the image quality and the diagnostic impact of intravascular optical coherence tomography (IV-OCT). In this study we demonstrate how these limitations of IV-OCT can be addressed by using an imaging system that we called Heartbeat OCT, combining a fast Fourier Domain Mode Locked laser, fast pullback, and a micromotor actuated catheter, designed to examine a coronary vessel in less than one ...
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    12. Investigating biofilm structure developing on carriers from lab-scale moving bed biofilm reactors based on light microscopy and optical coherence tomography

      Investigating biofilm structure developing on carriers from lab-scale moving bed biofilm reactors based on light microscopy and optical coherence tomography
      This study focused on characterizing the structure of biofilms developed on carriers used in lab-scale moving bed biofilm reactors. Both light microscopy (2D) and optical coherence tomography (OCT) were employed to track the biofilm development on carriers of different geometry and under different aeration rates. Biofilm structure was further characterized with respect to average biofilm thickness, biofilm growth velocity, biomass volume, compartment filling degree, surface area, etc. The results showed ...
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    13. NIR Micro Beam-splitter by Saw-dicing of Glass Substrate for Optical Coherence Tomography

      NIR Micro Beam-splitter by Saw-dicing of Glass Substrate for Optical Coherence Tomography
      This paper reports the fabrication of a near infrared (NIR) micro beam-splitter (MBS) for Optical Coherence Tomography (OCT) applications. The proposed configuration is based on saw-dicing micromachining of glass substrate combined with thin film deposition of a dielectric multilayer. In order to obtain a splitting with horizontal and vertical transmitted/reflected beams, a 45 surface was fabricated with conventional dicing blades. A dielectric multilayer based only in four thin films ...
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    14. A Micromotor Catheter for Intravascular Optical Coherence Tomography

      A Micromotor Catheter for Intravascular Optical Coherence Tomography
      We have developed a new form of intravascular optical coherence tomography (IV-OCT) that allows the extremely fast acquisition of high-resolution images of the coronary arteries. This process leads to much better image quality by eliminating cardiac motion artefacts and undersampling. It relies on a catheter that incorporates a synchronous micromotor with a diameter of 1.0 mm and a rotational speed of up to 5600 revolutions per second, enabling an ...
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    15. Optical coherence tomography complemented by hyperspectral imaging for the study of protective wood coatings

      Optical coherence tomography complemented by hyperspectral imaging for the study of protective wood coatings
      Optical coherence tomography (OCT) is a contactless and non-destructive testing (NDT) technique based on low-coherence interferometry. It has recently become a popular NDT-tool for evaluating cultural heritage. In this study, protective coatings on wood and their penetration into the wood structure were measured with a customized infrared fiber optic OCT instrument. In order to enhance the understanding of the OCT measurements of coatings on real wooden samples, an optimization of ...
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    16. 1-15 of 48 1 2 3 4 »
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  2. About Delft University of Technology

    Delft University of Technology

    Delft University of Technology (Technische Universiteit Delft), also known as TU Delft, is the largest and oldest Dutch public technical university, located in Delft, Netherlands. With eight faculties and numerous research institutes it hosts over 15,000 students (undergraduate and postgraduate), more than 2,600 scientists (including more than 200 professors), over 1,800 doctoral students, and more than 2,000 people in the support and management staff.