1. David Huang

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    1. Mentioned In 288 Articles

    2. Projection-resolved optical coherence tomography angiography exhibiting early flow prior to clinically observed retinal angiomatous proliferation

      Projection-resolved optical coherence tomography angiography exhibiting early flow prior to clinically observed retinal angiomatous proliferation
      Purpose The purpose of this study is to analyze early retinal angiomatous proliferation (RAP) utilizing a novel imaging modality, Projection-Resolved Optical Coherence Tomography Angiography (PR-OCTA). Observations Five months prior to the diagnosis of a RAP lesion, cross-sectional PR-OCTA demonstrated flow in the outer retina contiguous with the deep retinal capillary plexus (DCP) and adjacent to a small pigment epithelial detachment. After development of a clinically visible RAP lesion, cross-sectional PR-OCTA ...
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    3. Oregon Health & Science University Receives NIH Grant for Functional and Structural Optical Coherence Tomography for Glaucoma

      Oregon Health & Science University Receives NIH Grant  for Functional and Structural Optical Coherence Tomography for Glaucoma
      ...59,269 for Functional and Structural Optical Coherence Tomography for Glaucoma. The principal investigator is David Huang. The program began in 2013 and ends in 2021. Below is a summary of the proposed work.

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    4. Register Now for the International Congress on OCT Angiography, "en face" OCT, and Advances in OCT on December 15th in Rome Italy which Already has over 1,000 Attendees.

      Register Now for the International Congress on OCT Angiography, "en face" OCT, and Advances in OCT  on December 15th in Rome Italy which Already has over 1,000 Attendees.
      ...zation, friendly atmosphere, sweet weather and Rome beauty. The conference organizers include Bruno Lumbroso, David Huang, Gabriel Coscas, Yali Jia, K. Bailey Freund, Richard Rosen, Philip Rosenfeld, David Sarraf, Eric S...
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    5. Comparison of Glaucoma Progression Detection by Optical Coherence Tomography and Visual Field

      Comparison of Glaucoma Progression Detection by Optical Coherence Tomography and Visual Field
      Purpose To compare longitudinal glaucoma progression detection using optical coherence tomography (OCT) and visual field (VF). Design Validity assessment Method We analyzed subjects with more than 5 follow-up visits (every 6 months) in the multi-center Advanced Imaging for Glaucoma Study. Fourier-domain optical coherence tomography (OCT) was used to map the thickness of the peripapillary retinal nerve fiber layer (NFL) and ganglion cell complex (GCC). OCT-based progression detection was defined as ...
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    6. Optical coherence tomography angiography enhances the detection of optic nerve damage in multiple sclerosis

      Optical coherence tomography angiography enhances the detection of optic nerve damage in multiple sclerosis
      Background Quantitative assessment of optic nerve damage is important in the evaluation of optic neuritis (ON) and multiple sclerosis (MS). Objective To detect optic nerve damage using optical coherence tomography (OCT) and OCT angiography in MS. Methods Peripapillary retinal nerve fibre layer (NFL) thickness, macular ganglion cell complex (GCC) thickness and Optic Nerve Head Flow Index (ONH-FI) were measured. The ONH-FI was defined as flow signal averaged over the optic ...
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    7. Optical Coherence Tomography Angiography of the Peripapillary Retina in Primary Angle-Closure Glaucoma

      Optical Coherence Tomography Angiography of the Peripapillary Retina in Primary Angle-Closure Glaucoma
      Purpose To measure the change of peripapillary retinal vessel density (VD) in eyes with a history of acute primary angle closure glaucoma (PACG). Design Case-control study. Methods Twenty-one consecutive Chinese patients with history of unilateral acute PACG were enrolled. Eyes with acute PACG constituted the case group, while the contralateral eyes without attack constituted the control. All patients underwent ophthalmic examinations including best-corrected visual acuity, intraocular pressure, and visual field ...
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    8. Handheld OCT Angiography and Ultra–Wide-Field OCT in Retinopathy of Prematurity

      Handheld OCT Angiography and Ultra–Wide-Field OCT in Retinopathy of Prematurity
      Importance Retinopathy of prematurity (ROP) is a leading cause of childhood blindness worldwide. Optical coherence tomography (OCT) has improved the care of adults with vitreoretinal disease, and OCT angiography (OCTA) is demonstrating promise as a technique to visualize the retinal vasculature with lower risk and cost than fluorescein angiography. However, to date, there are no commercially available devices able to obtain ultrawide-field OCT or OCTA images in neonates. Objective To ...
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    9. Projection-Resolved Optical Coherence Tomography Angiography of Macular Retinal Circulation in Glaucoma

      Projection-Resolved Optical Coherence Tomography Angiography of Macular Retinal Circulation in Glaucoma
      Purpose To detect macular perfusion defects in glaucoma using projection-resolved optical coherence tomography (OCT) angiography. Design Prospective observation study. Participants A total of 30 perimetric glaucoma and 30 age-matched normal participants were included. Methods One eye of each participant was imaged using 6 6mm macular OCT angiography (OCTA) scan pattern by 70-kHz 840-nm spectral-domain OCT. Flow signal was calculated by the split-spectrum amplitude-decorrelation angiography algorithm. A projection-resolved OCTA (PR-OCTA) algorithm ...
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    10. Regression-based algorithm for bulk motion subtraction in optical coherence tomography angiography

      Regression-based algorithm for bulk motion subtraction in optical coherence tomography angiography
      We developed an algorithm to remove decorrelation noise due to bulk motion in optical coherence tomography angiography (OCTA) of the posterior eye. In this algorithm, OCTA B-frames were divided into segments within which the bulk motion velocity could be assumed to be constant. This velocity was recovered using linear regression of decorrelation versus the logarithm of reflectance in axial lines (A-lines) identified as bulk tissue by percentile analysis. The fitting ...
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    11. Methods and systems to measure corneal epithelial thickness and power, stromal thickness, subepithelial corneal power and topography for disease diagnosis

      Methods and systems to measure corneal epithelial thickness and power, stromal thickness, subepithelial corneal power and topography for disease diagnosis
      This invention discloses methods and systems for measuring corneal epithelial thickness and power, stromal thickness, subepitheila corneal power and topography. The systems and methods disclosed herein are non-invasive, non-contact and automated imaging methods which preferably makes use of Fourier-domain optical tomography. Also disclosed herein are scanning patterns and image analysis methods for utilizing and analyzing Fourier-domain optical coherence tomography images to obtain information about conical epithelial and stromal properties as ...
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    12. Extended axial imaging range, widefield swept source optical coherence tomography angiography

      Extended axial imaging range, widefield swept source optical coherence tomography angiography
      We developed a high-speed, swept source OCT system for widefield OCT angiography (OCTA) imaging. The system has an extended axial imaging range of 6.6 mm. An electrical lens is used for fast, automatic focusing. The recently developed split-spectrum amplitude and phase-gradient angiography allow high-resolution OCTA imaging with only two B-scan repetitions. An improved post-processing algorithm effectively removed trigger jitter artifacts and reduced noise in the flow signal. We demonstrated ...
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    13. Interchangeability and reliability of macular perfusion parameter measurements using optical coherence tomography angiography

      Interchangeability and reliability of macular perfusion parameter measurements using optical coherence tomography angiography
      Aim The aim of the study was to investigate the interchangeability and reliability of macular perfusion measurements using optical coherence tomography angiography. Methods A prospective cross-sectional observational study. Healthy adult Chinese subjects were recruited. Macular perfusion parameters were automatically analysed by software included in a spectral-domain optical coherence tomography system. The vessel density (VD) of the whole, parafovea, superior-hemi, inferior-hemi, fovea, temporal, superior, nasal and inferior quadrants as well as ...
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    14. 1-15 of 288 1 2 3 4 ... 18 19 20 »
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  2. About David Huang

    David Huang

    David Huang is Peterson Professor of Ophthalmology, professor of biomedical engineering, and director of the Center for Ophthalmic Optics and Lasers (www.COOLLab.net) in the Casey Eye Institute at the Oregon Health and Science University in Portland. The COOL lab conducts research on retinal diseases, anterior eye disease, glaucoma, and other optic nerve diseases. He is a co-inventor of OCT and has contributed to polarization-sensitive, swept-source, spectroscopic, and anterior eye OCT as well as OCT angiography. He is also an inventor of laser therapeutic devices and mobile diagnostic technology, and a founder of Gobiquity Mobile Health (www.gobiquity.com), which makes mobile diagnostic apps for professional and home use. Huang shared the 2012 António Champalimaud Vision Award and received the Association for Research in Vision and Ophthalmology’s Jonas Friedenwald Award and the American Academy of Ophthalmology’s Senior Achievement Award. He is a fellow of the National Academy of Inventors.

  3. Quotes

    1. I am pleased to see how well the OCT technology has evolved over the past 25 years to help diagnose and treat the most common causes of blindness, age-related macular degeneration, diabetic retinopathy and glaucoma...OCT use continues to grow exponentially in ophthalmology and other medical specialties, including cardiology, dermatology, neurology and gastroenterology.
      In Co-invented by OHSU's Dr. David Huang 25 years ago, OCT technology helps stop blindness
    2. OCT is a big saver of healthcare dollars – the guidance of anti-vascular endothelial growth factor therapy in age-related macular degeneration alone saves billions of dollars per year by avoiding unnecessary injections.
      In Optical Coherence Tomography Industry Has Provided Well Over 20,000 Person-Years of Direct Employment
    3. OCT is the most commonly used eye imaging test in the management of the leading causes of blindness today: macular degeneration, diabetic retinopathy and glaucoma. I am proud to be a key contributor to the technology that is preserving vision for people around the world.
      In OHSU Casey Eye Institute Inventor Dr. David Huang Earns International Award for Advances in Eye Imaging
    4. Seeing the blood flow in many layers of the retina is incredibly important because the most important causes of blindness in the world are due to abnormal blood circulation.
      In OHSU Casey Eye Institute Inventor Dr. David Huang Earns International Award for Advances in Eye Imaging
    5. There are a few circumstances where mapping the posterior surface is also useful, for example, in post-LASIK cataract surgery intraocular lens calculations, where measuring the anterior surface alone is not sufficient to really accurately measure the net corneal power.
      In Versatile corneal, anterior segment imaging technologies improve accuracy
    6. Confocal microscopy of the cornea has been around for a long time but it still doesn’t have a lot of specificity in looking at microorganisms...Some sort of in vivo staining or fluorescence that allows us to really distinguish infections or microorganisms with confocal imaging would be great
      In Versatile corneal, anterior segment imaging technologies improve accuracy
    7. OCT has higher resolution than any of the anterior segment modalities....I think eventually any function that a topography, ultrasound or slit scanning can do, OCT can do better.
      In OCT devices increasingly finding use outside retinal practice
    8. OCT has higher resolution than any of the anterior segment modalities...I think eventually any function that a topography, ultrasound or slit scanning can do, OCT can do better.”
      In OCT devices increasingly finding use outside retinal practice
    9. It just requires special scanning software that could easily be put on the OCT machines that most retinal specialists have.
      In Shining Light on Diabetes-Related Blindness
    10. People with poor blood flow don't respond well to some of the laser treatments used for retinopathy, and they are at a higher risk for proliferative retinopathy.
      In Shining Light on Diabetes-Related Blindness