1. David Huang

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    1. Mentioned In 180 Articles

    2. Noninvasive Ocular Angiography by Optical Coherence Tomography (Book Chapter)

      Noninvasive Ocular Angiography by Optical Coherence Tomography (Book Chapter)

      Diabetic retinopathy, age-related macular degeneration, and glaucoma are all associated with impaired circulation. Noninvasive assessment of ocular circulation would be very powerful for understanding and diagnosing these eye diseases. Using high-speed optical coherence tomography (OCT), we developed a new OCT angiography algorithm called split-spectrum amplitude-decorrelation angiography (SSADA) for imaging ocular microcirculation. Here, the system and theory of this novel OCT angiography technique are reviewed; its capabilities for imaging retinal, choroidal, and optic nerve head blood flow are demonstrated; and its limitation is discussed.

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    3. Advanced Imaging for Glaucoma Study: Design, Baseline Characteristics, and Inter-Site Comparison

      Advanced Imaging for Glaucoma Study: Design, Baseline Characteristics, and Inter-Site Comparison

      Purpose To report the baseline characteristics of the participants in the Advanced Imaging for Glaucoma Study. To compare the participating sites for variations among subjects and the performance of imaging instruments. Design Multi-center longitudinal observational cohort study Methods A total of 788 participants (1,329 eyes) were enrolled from three academic referral centers. There were 145 participants (289 eyes) in the normal group, 394 participants (663 eyes) in the glaucoma suspect/preperimetric glaucoma group, and 249 participants (377 eyes) in the perimetric glaucoma group. Participants underwent a full clinical exam, standard automated perimetry, and imaging with time-domain and Fourier-domain optical ...

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    4. OCT Vitrectomy Probe

      OCT Vitrectomy Probe

      Disclosed herein is a vitrectomy probe, comprising a beam steering system configured to receive a light beam from a sample fiber of an optical coherence tomography instrument; a fundus illumination system configured to receive a beam of white light from a white light source via a multimode fiber; a dichroic mirror; and a beam delivery system configured to illuminate the retina of a subject.

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    5. Variability and Repeatability of Quantitative, Fourier Domain-OCT Doppler Blood Flow in Young and Elderly Healthy Subjects

      Variability and Repeatability of Quantitative, Fourier Domain-OCT Doppler Blood Flow in Young and Elderly Healthy Subjects

      The purpose of this study was to determine the within-session variability and between-session repeatability of spectral Fourier-domain optical coherence tomography (Doppler FD-OCT) Doppler retinal blood flow measurements in young, and elderly subjects. Methods: Doppler FD-OCT blood flow was measured using the RTVue system (Optovue Inc., USA). One eye of each of 20 healthy young (24.7 ± 2.7 years) and 16 healthy elderly (64.6 ± 5.1 years) subjects was randomly selected and the pupil was dilated. The double circular scanning pattern of the RTVue was employed. Six Doppler FD-OCT measurements (i.e. each separate measurement comprising an upper, and ...

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    6. Oregon Health & Science University Receives NIH Grant for Functional and Structural Optical Coherence Tomgoraphy for Glaucoma

      Oregon Health & Science University Receives NIH Grant  for Functional and Structural Optical Coherence Tomgoraphy for Glaucoma
      ...34,129 for Functional and Structural Optical Coherence Tomgoraphy for Glaucoma. The principal investigator is David Huang. The program began in 2013 and ends in 2017. Below is a summary of the proposed work.   Glauco...
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    7. Oregon Health & Science University Receives 2014 NIH Guiding The Treatment of Anterior Eye Disease with Optical Coherence Tomography

      Oregon Health & Science University Receives 2014 NIH  Guiding The Treatment of Anterior Eye Disease with Optical Coherence Tomography
      ...uiding The Treatment of Anterior Eye Disease with Optical Coherence Tomography. The principal investigator is David Huang. The program began in 2007 and ends in 2016. Below is a summary of the proposed work.

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    8. Software Postdoctoral Position in Optical imaging at Casey Eye Institute, Oregon Health & Science University

      Software Postdoctoral Position in Optical imaging at Casey Eye Institute, Oregon Health & Science University
      ...and software development (GPU programming) are also desirable. The successful candidate will be supervised by David Huang, MD, PhD and Yali Jia, PhD and also closely work with retina faculties at Casey Eye Institute. St...
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    9. Dual-Angle Protocol for Doppler Optical Coherence Tomography to Improve Retinal Blood Flow Measurement

      Dual-Angle Protocol for Doppler Optical Coherence Tomography to Improve Retinal Blood Flow Measurement

      Purpose: To compare the performance of two different multiple-scan protocols for total retinal blood flow (TRBF) measurement using Doppler optical coherence tomography (OCT). Methods: In the “single-angle” protocol, five Doppler scans were acquired at a single beam angle. In the “dual-angle” protocol, three scans were obtained with the OCT beam passing through the supranasal portion of the pupil and three through the infranasal portion. The data were analyzed using a custom software termed “Doppler OCT of Retinal Circulation” (DOCTORC) to generate TRBF measurements. In DOCTORC, the measurement of a vein was considered unreliable if the Doppler angle was less than ...

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    10. Assessment of total retinal blood flow using Doppler Fourier Domain Optical Coherence Tomography during systemic hypercapnia and hypocapnia

      Assessment of total retinal blood flow using Doppler Fourier Domain Optical Coherence Tomography during systemic hypercapnia and hypocapnia
      ... Department of Ophthalmology and Vision Science, Toronto Western Research Institute, Toronto, Ontario, Canada David Huang Oregon Health & Science University, Portland, Oregon Ou Tan Oregon Health & Science University, Po...
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    11. Scanning and processing using optical coherence tomography

      Scanning and processing using optical coherence tomography

      In accordance with some embodiments, a method of eye examination includes acquiring OCT data with a scan pattern centered on an eye cornea that includes n radial scans repeated r times, c circular scans repeated r times, and n* raster scans where the scan pattern is repeated m times, where each scan includes a A-scans, and where n is an integer that is 0 or greater, r is an integer that is 1 or greater, c is an integer that is 0 or greater, n* is an integer that is 0 or greater, m is an integer that is 1 ...

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  2. About David Huang

    David Huang

    David Huang joined the Oregon Health & Science University (OHSU) Casey Eye Institute in 2010 as a Professor of Ophthalmology. Dr. Huang earned the MD degree from Harvard University and a PhD in Medical Engineering and Medical Physics from Massachusetts Institute of Technology. He received ophthalmology residency training at USC and fellowship training in cornea, external disease and refractive surgery at Emory University School of Medicine. Before joining the OHSU faculty, Dr. Huang was on the staff of the Cole Eye Institute of the Cleveland Clinic and later on the faculty of Doheny Eye Institute of University of Southern California. Dr. Huang has been named one of best doctors in America by his peers (www.bestdoctors.com) and among the top LASIK surgeons by www.trustedlasiksurgeons.com based on research experience and premier patient care. Dr. Huang is known for his innovations in applying laser and optical technology to eye diseases. He is a co-inventor of optical coherence tomography (OCT), an imaging technology that has been applied to the measurement of eye structures with unprecedented precision. He continues his research in applying OCT to corneal and cataract surgery, glaucoma and retinal diseases

  3. Quotes

    1. OCT is the most commonly used eye imaging test in the management of the leading causes of blindness today: macular degeneration, diabetic retinopathy and glaucoma. I am proud to be a key contributor to the technology that is preserving vision for people around the world.
      In OHSU Casey Eye Institute Inventor Dr. David Huang Earns International Award for Advances in Eye Imaging
    2. Seeing the blood flow in many layers of the retina is incredibly important because the most important causes of blindness in the world are due to abnormal blood circulation.
      In OHSU Casey Eye Institute Inventor Dr. David Huang Earns International Award for Advances in Eye Imaging
    3. There are a few circumstances where mapping the posterior surface is also useful, for example, in post-LASIK cataract surgery intraocular lens calculations, where measuring the anterior surface alone is not sufficient to really accurately measure the net corneal power.
      In Versatile corneal, anterior segment imaging technologies improve accuracy
    4. Confocal microscopy of the cornea has been around for a long time but it still doesn’t have a lot of specificity in looking at microorganisms...Some sort of in vivo staining or fluorescence that allows us to really distinguish infections or microorganisms with confocal imaging would be great
      In Versatile corneal, anterior segment imaging technologies improve accuracy
    5. OCT has higher resolution than any of the anterior segment modalities....I think eventually any function that a topography, ultrasound or slit scanning can do, OCT can do better.
      In OCT devices increasingly finding use outside retinal practice
    6. OCT has higher resolution than any of the anterior segment modalities...I think eventually any function that a topography, ultrasound or slit scanning can do, OCT can do better.”
      In OCT devices increasingly finding use outside retinal practice
    7. It just requires special scanning software that could easily be put on the OCT machines that most retinal specialists have.
      In Shining Light on Diabetes-Related Blindness
    8. People with poor blood flow don't respond well to some of the laser treatments used for retinopathy, and they are at a higher risk for proliferative retinopathy.
      In Shining Light on Diabetes-Related Blindness