1. Daniël M. de Bruin

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    1. Mentioned In 58 Articles

    2. Optical Coherence Tomography in Bladder Cancer (Book Chapter)

      Optical Coherence Tomography in Bladder Cancer (Book Chapter)
      The current diagnostic standard for grading and staging of non-muscle-invasive bladder cancer (NMIBC) is based on the histopathology obtained during transurethral resection of the bladder tumour (TURBT) or biopsies. Although considered reference standard, this technique has some limitations: First, no real-time intraoperative histological information is obtained on stage and grade. Real-time intraoperative histological information could be helpful when NMIBC is treated by electric coagulation or laser ablation. The urologist has ...
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    3. The Value of Optical Coherence Tomography in Determining Surgical Margins in Squamous Cell Carcinoma of the Vulva: A Single-Center Prospective Study.

      The Value of Optical Coherence Tomography in Determining Surgical Margins in Squamous Cell Carcinoma of the Vulva: A Single-Center Prospective Study.
      Background: Vulvar squamous cell carcinoma (VSCC) is treated with wide local excision. The challenge is to remove as much skin as necessary to prevent recurrence, but meanwhile preserve genital skin to diminish morbidity. Optical coherence tomography (OCT) is a noninvasive imaging tool that produces cross-sectional images. Optical coherence tomography could be helpful in determining appropriate surgical margins during excision of VSCC. Objective: This study aimed to assess the value of ...
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    4. Comparison of optical coherence tomography and histopathology in quantitative assessment of goat talus articular cartilage

      Comparison of optical coherence tomography and histopathology in quantitative assessment of goat talus articular cartilage
      Background and purpose Optical coherence tomography (OCT) is a light-based imaging technique suitable for depiction of thin tissue layers such as articular cartilage. Quantification of results and direct comparison with a reference standard is needed to confirm the role of OCT in cartilage evaluation. Materials and methods Goat talus articular cartilage repair was assessed quantitatively with OCT and compared with histopathology using semi-automated analysis software. Osteochondral defects were created centrally ...
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    5. Video Interview on Optical coherence tomography as a tool for in vivo staging and grading of upper urinary tract urothelial cell carcinoma: Comparison with biopsies and histopathology of the resected specimen

      Video Interview on Optical coherence tomography as a tool for in vivo staging and grading of upper urinary tract urothelial cell carcinoma: Comparison with biopsies and histopathology of the resected specimen
      Introduction and Objectives: Optical Coherence Tomography (OCT) has potential to provide real-time information on UUT-UC grade and stage. In this study we compare a) biopsy and b) OCT with gold standard histopathology of the resected specimen (HRS) for grading and staging of low- and high-grade UUT-UC. Methods: 16 patients with UUT-UC underwent diagnostic URS, including OCT and biopsy of places with visible tumour. The 2.7 Fr OCT probe was ...
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    6. Functional optical coherence tomography of pigmented lesions

      Functional optical coherence tomography of pigmented lesions
      Background Cutaneous melanomas are diagnosed worldwide in 231 130 patients per year. The sensitivity and specificity of melanoma diagnosis expresses the need for an additional diagnostic method. Optical coherence tomography (OCT) has shown that it allows morphological (qualitative) description of image features and quantitative analysis of pathology related light scattering by means of the attenuation coefficient ( oct ). Objective We hypothesize that OCT images of nevi will differ qualitatively and quantitatively ...
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    7. Treatment of coronary bifurcation lesions with the Absorb bioresorbable vascular scaffold in combination with the Tryton dedicated coronary bifurcation stent: evaluation using two- and three-dimensional optical coherence tomography

      Treatment of coronary bifurcation lesions with the Absorb bioresorbable vascular scaffold in combination with the Tryton dedicated coronary bifurcation stent: evaluation using two- and three-dimensional optical coherence tomography
      Aims: The Tryton bifurcation stent has been developed to improve clinical outcomes after treatment of bifurcation lesions. Limited data are available on the use of the Absorb bioresorbable vascular scaffold (BVS) in bifurcation lesions with side branches 2 mm. We present here the acute procedural results and midterm clinical follow-up of the first-in-man combined use of the Tryton stent and the Absorb scaffold for the treatment of complex bifurcation lesions ...
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    8. Side branch healing patterns of the Tryton dedicated bifurcation stent: a 1-year optical coherence tomography follow-up study

      Side branch healing patterns of the Tryton dedicated bifurcation stent: a 1-year optical coherence tomography follow-up study
      The bare-metal Tryton Side Branch (SB) Stent (Tryton Medical, Durham, NC, USA) is used with a drug-eluting stent (DES) in the main branch (MB) to treat bifurcation lesions. It is argued that a drug-eluting Tryton-version is needed to improve clinical outcomes, although previous registries have shown good clinical results. More insights in neo-intimal hyperplasia (NIH) growth patterns of the Tryton treatment strategy are needed to decide if and where to ...
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    9. Clinical applications of functional optical coherence tomography (Thesis)

      Clinical applications of functional optical coherence tomography (Thesis)
      The purpose of the work presented in this thesis is to show the potential of functional optical coherence tomography (OCT) to discriminate pathological from normal tissues in several clinical settings, by means of the attenuation coefficient. To that end, several fundamental studies were carried out to increase the fundamental understanding of the measured signals (in phantoms, during apoptosis) and both ex and in vivo investigations are performed in the urological ...
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    10. Feature Of The Week 11/10/13: Volumetric In-Vivo Visualization of Upper Urinary Tract Tumors Using Optical Coherence Tomography: A Pilot Study

      Feature Of The Week 11/10/13: Volumetric In-Vivo Visualization of Upper Urinary Tract Tumors Using Optical Coherence Tomography: A Pilot Study
      Optical Coherence Tomography (OCT) has proven a powerful tool for ophthalmologists to make clinical decisions for a wide range of blinding diseases and the there are now ~20 million ophthalmic OCT patient scans per year. Significant progress is also being made in intravascular imaging where OCT is emerging as a tool for both clinical decision making and the understanding of cardiovascular disease and development of new therapeutic tools. OCT also ...
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    11. Three-dimensional optical coherence tomography evaluation of a left main bifurcation lesion treated with ABSORB® bioresorbable vascular scaffold including fenestration and dilatation of the side branch - Corrected Proof

      Three-dimensional optical coherence tomography evaluation of a left main bifurcation lesion treated with ABSORB® bioresorbable vascular scaffold including fenestration and dilatation of the side branch - Corrected Proof
      Previous trials on the ABSORB (Abbott Vascular, Santa Clara, USA) everolimus-eluting bioresorbable vascular scaffold (BVS) were predominated by relatively low-risk lesions, excluding patients with left main coronary artery (LMCA) lesions and bifurcation lesions involving side branches 2mm . Little is known about the safety and feasibility of fenestration and dilation of the side branch ostium after BVS placement .
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    12. Volumetric In-Vivo Visualization of Upper Urinary Tract Tumors Using Optical Coherence Tomography: A Pilot Study

      Volumetric In-Vivo Visualization of Upper Urinary Tract Tumors Using Optical Coherence Tomography: A Pilot Study
      Purpose Knowledge on tumor stage and grade is paramount for treatment decision in Upper Urinary Tract Urothelial Carcinoma (UUT-UC), but cannot be accurately assessed by current techniques. Optical Coherence Tomography (OCT) is a technique, which can hypothetically provide the urologist with real-time intra-operative information on tumor grade and stage. In this pilot study the first results of OCT in grading and staging of UUT-UC are presented. Material Methods Eight consecutive ...
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    13. Optical biopsy of epithelial cancers by optical coherence tomography (OCT)

      Optical biopsy of epithelial cancers by optical coherence tomography (OCT)
      Optical coherence tomography (OCT) is an optical technique that measures the backscattering of near-infrared light by tissue. OCT yields in 2D and 3D images at micrometer-scale resolution, thus providing optical biopsies, approaching the resolution of histopathological imaging. The technique has shown to allow in vivo differentiation between benign and malignant epithelial tissue, through qualitative assessment of OCT images, as well as by quantitative evaluation, e.g., functional OCT. This study ...
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    14. Successful treatment of a long tapered lesion with two overlapping ABSORB® bioresorbable vascular scaffolds of different diameters: Evaluation by three-dimensional optical coherence tomography

      Successful treatment of a long tapered lesion with two overlapping ABSORB® bioresorbable vascular scaffolds of different diameters: Evaluation by three-dimensional optical coherence tomography
      ... Medical Center, University of Amsterdam, Amsterdam, The Netherlands + Contributed equally to this paper. , * D. Martijn de Bruin Affiliations + Department of Biomedical Engineering and Physics, Academic Medical Center, ...
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    15. Optical coherence tomography in vulvar intraepithelial neoplasia

      Optical coherence tomography in vulvar intraepithelial neoplasia
      Vulvar squamous cell carcinoma (VSCC) is a gynecological cancer with an incidence of two to three per 100,000 women. VSCC arises from vulvar intraepithelial neoplasia (VIN), which is diagnosed through painful punch biopsy. In this study, optical coherence tomography (OCT) is used to differentiate between normal and VIN tissue. We hypothesize that (a) epidermal layer thickness measured in OCT images is different in normal tissue and VIN, and (b ...
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    16. Feature Of The Week 9/2/12: Academic Medical Center at The University of Amsterdam Investigates Comparison of RNFL Thickness Measurements by SD-OCT Systems Using a Phantom Eye Model

      Feature Of The Week 9/2/12: Academic Medical Center at The University of Amsterdam Investigates Comparison of RNFL Thickness Measurements by SD-OCT Systems Using a Phantom Eye Model
      We developed a multi-layered phantom eye model that distinguishes instrumental from biological variation, to quantify differences in retinal nerve fiber layer (RNFL) thickness measurements by various spectral-domain optical coherence tomography (SD-OCT) systems. The eye model comprised a glass lens, water as vitreous and silicone elastomer based layers mimicking the retina (top layer thickness = 49 m). We tested 3 RTVue OptoVue, 3 Cirrus Zeiss, 3 3DOCT-1000 Topcon and 3 Spectralis Heidelberg ...
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    17. 31-45 of 58 « 1 2 3 4 »
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  2. About Daniël M. de Bruin

    Daniël M. de Bruin

    Daniël M. de Bruin is in the Department of Biomedical Engineering and Physics at the Academic Medical Center Amsterdam, The Netherlands.