1. Daniël M. de Bruin

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    1. Mentioned In 63 Articles

    2. Prostate cancer diagnosis: the feasibility of needle-based optical coherence tomography

      Prostate cancer diagnosis: the feasibility of needle-based optical coherence tomography
      The objective of this study is to demonstrate the feasibility of needle-based optical coherence tomography (OCT) and functional analysis of OCT data along the full pullback trajectory of the OCT measurement in the prostate, correlated with pathology. OCT images were recorded using a commercially available C7-XR OCT Intravascular Imaging System interfaced to a C7 Dragonfly intravascular 0.9-mm-diameter imaging probe. A computer program was constructed for automated image attenuation analysis ...
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    3. Detection of buried Barrett’s glands after radiofrequency ablation with volumetric laser endomicroscopy

      Detection of buried Barrett’s glands after radiofrequency ablation with volumetric laser endomicroscopy
      Background and Aims The prevalence and clinical relevance of buried Barretts glands (BB) after radiofrequency ablation (RFA) in Barretts esophagus (BE) are debated. Recent optical coherence tomography studies demonstrated a high prevalence of BBs. Direct histological correlation, however, has been lacking. Volumetric laser endomicroscopy (VLE) is a second-generation optical coherence tomography system capable of scanning a large surface of the esophageal wall layers with low-power microscopy resolution. The aim was ...
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    4. Volumetric laser endomicroscopy in Barrett's esophagus: a feasibility study on histological correlation

      Volumetric laser endomicroscopy in Barrett's esophagus: a feasibility study on histological correlation
      Volumetric laser endomicroscopy (VLE) is a novel balloon-based optical coherence tomography (OCT) imaging technique that may improve detection of early neoplasia in Barrett's esophagus (BE). Most OCT studies lack a direct correlation between histology and OCT images. The aim is to investigate the optimal approach for achieving one-to-one correlation of ex-vivo VLE images of endoscopic resection (ER) specimens with histology. BE patients with and without early neoplasia underwent ER ...
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    5. In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses

      In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses
      Optical coherence tomography (OCT) is the optical equivalent of ultrasound imaging, based on the backscattering of near infrared light. OCT provides real time images with a 15 m axial resolution at an effective tissue penetration of 2-3 mm. Within the OCT images the loss of signal intensity per millimeter of tissue penetration, the attenuation coefficient, is calculated. The attenuation coefficient is a tissue specific property, providing a quantitative parameter for ...
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    6. Functional optical coherence tomography of pigmented lesions

      Functional optical coherence tomography of pigmented lesions
      Background Cutaneous melanomas are diagnosed worldwide in 231 130 patients per year. The sensitivity and specificity of melanoma diagnosis expresses the need for an additional diagnostic method. Optical coherence tomography (OCT) has shown that it allows morphological (qualitative) description of image features and quantitative analysis of pathology related light scattering by means of the attenuation coefficient ( oct ). Objective We hypothesize that OCT images of nevi will differ qualitatively and quantitatively ...
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    7. Optical Coherence Tomography in Bladder Cancer (Book Chapter)

      Optical Coherence Tomography in Bladder Cancer (Book Chapter)
      The current diagnostic standard for grading and staging of non-muscle-invasive bladder cancer (NMIBC) is based on the histopathology obtained during transurethral resection of the bladder tumour (TURBT) or biopsies. Although considered reference standard, this technique has some limitations: First, no real-time intraoperative histological information is obtained on stage and grade. Real-time intraoperative histological information could be helpful when NMIBC is treated by electric coagulation or laser ablation. The urologist has ...
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    8. The Value of Optical Coherence Tomography in Determining Surgical Margins in Squamous Cell Carcinoma of the Vulva: A Single-Center Prospective Study.

      The Value of Optical Coherence Tomography in Determining Surgical Margins in Squamous Cell Carcinoma of the Vulva: A Single-Center Prospective Study.
      Background: Vulvar squamous cell carcinoma (VSCC) is treated with wide local excision. The challenge is to remove as much skin as necessary to prevent recurrence, but meanwhile preserve genital skin to diminish morbidity. Optical coherence tomography (OCT) is a noninvasive imaging tool that produces cross-sectional images. Optical coherence tomography could be helpful in determining appropriate surgical margins during excision of VSCC. Objective: This study aimed to assess the value of ...
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    9. Comparison of optical coherence tomography and histopathology in quantitative assessment of goat talus articular cartilage

      Comparison of optical coherence tomography and histopathology in quantitative assessment of goat talus articular cartilage
      Background and purpose Optical coherence tomography (OCT) is a light-based imaging technique suitable for depiction of thin tissue layers such as articular cartilage. Quantification of results and direct comparison with a reference standard is needed to confirm the role of OCT in cartilage evaluation. Materials and methods Goat talus articular cartilage repair was assessed quantitatively with OCT and compared with histopathology using semi-automated analysis software. Osteochondral defects were created centrally ...
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    10. Video Interview on Optical coherence tomography as a tool for in vivo staging and grading of upper urinary tract urothelial cell carcinoma: Comparison with biopsies and histopathology of the resected specimen

      Video Interview on Optical coherence tomography as a tool for in vivo staging and grading of upper urinary tract urothelial cell carcinoma: Comparison with biopsies and histopathology of the resected specimen
      Introduction and Objectives: Optical Coherence Tomography (OCT) has potential to provide real-time information on UUT-UC grade and stage. In this study we compare a) biopsy and b) OCT with gold standard histopathology of the resected specimen (HRS) for grading and staging of low- and high-grade UUT-UC. Methods: 16 patients with UUT-UC underwent diagnostic URS, including OCT and biopsy of places with visible tumour. The 2.7 Fr OCT probe was ...
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    11. Functional optical coherence tomography of pigmented lesions

      Functional optical coherence tomography of pigmented lesions
      Background Cutaneous melanomas are diagnosed worldwide in 231 130 patients per year. The sensitivity and specificity of melanoma diagnosis expresses the need for an additional diagnostic method. Optical coherence tomography (OCT) has shown that it allows morphological (qualitative) description of image features and quantitative analysis of pathology related light scattering by means of the attenuation coefficient ( oct ). Objective We hypothesize that OCT images of nevi will differ qualitatively and quantitatively ...
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    12. Treatment of coronary bifurcation lesions with the Absorb bioresorbable vascular scaffold in combination with the Tryton dedicated coronary bifurcation stent: evaluation using two- and three-dimensional optical coherence tomography

      Treatment of coronary bifurcation lesions with the Absorb bioresorbable vascular scaffold in combination with the Tryton dedicated coronary bifurcation stent: evaluation using two- and three-dimensional optical coherence tomography
      Aims: The Tryton bifurcation stent has been developed to improve clinical outcomes after treatment of bifurcation lesions. Limited data are available on the use of the Absorb bioresorbable vascular scaffold (BVS) in bifurcation lesions with side branches 2 mm. We present here the acute procedural results and midterm clinical follow-up of the first-in-man combined use of the Tryton stent and the Absorb scaffold for the treatment of complex bifurcation lesions ...
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    13. Side branch healing patterns of the Tryton dedicated bifurcation stent: a 1-year optical coherence tomography follow-up study

      Side branch healing patterns of the Tryton dedicated bifurcation stent: a 1-year optical coherence tomography follow-up study
      The bare-metal Tryton Side Branch (SB) Stent (Tryton Medical, Durham, NC, USA) is used with a drug-eluting stent (DES) in the main branch (MB) to treat bifurcation lesions. It is argued that a drug-eluting Tryton-version is needed to improve clinical outcomes, although previous registries have shown good clinical results. More insights in neo-intimal hyperplasia (NIH) growth patterns of the Tryton treatment strategy are needed to decide if and where to ...
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    14. Clinical applications of functional optical coherence tomography (Thesis)

      Clinical applications of functional optical coherence tomography (Thesis)
      The purpose of the work presented in this thesis is to show the potential of functional optical coherence tomography (OCT) to discriminate pathological from normal tissues in several clinical settings, by means of the attenuation coefficient. To that end, several fundamental studies were carried out to increase the fundamental understanding of the measured signals (in phantoms, during apoptosis) and both ex and in vivo investigations are performed in the urological ...
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    15. Feature Of The Week 11/10/13: Volumetric In-Vivo Visualization of Upper Urinary Tract Tumors Using Optical Coherence Tomography: A Pilot Study

      Feature Of The Week 11/10/13: Volumetric In-Vivo Visualization of Upper Urinary Tract Tumors Using Optical Coherence Tomography: A Pilot Study
      Optical Coherence Tomography (OCT) has proven a powerful tool for ophthalmologists to make clinical decisions for a wide range of blinding diseases and the there are now ~20 million ophthalmic OCT patient scans per year. Significant progress is also being made in intravascular imaging where OCT is emerging as a tool for both clinical decision making and the understanding of cardiovascular disease and development of new therapeutic tools. OCT also ...
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    16. Three-dimensional optical coherence tomography evaluation of a left main bifurcation lesion treated with ABSORB® bioresorbable vascular scaffold including fenestration and dilatation of the side branch - Corrected Proof

      Three-dimensional optical coherence tomography evaluation of a left main bifurcation lesion treated with ABSORB® bioresorbable vascular scaffold including fenestration and dilatation of the side branch - Corrected Proof
      Previous trials on the ABSORB (Abbott Vascular, Santa Clara, USA) everolimus-eluting bioresorbable vascular scaffold (BVS) were predominated by relatively low-risk lesions, excluding patients with left main coronary artery (LMCA) lesions and bifurcation lesions involving side branches 2mm . Little is known about the safety and feasibility of fenestration and dilation of the side branch ostium after BVS placement .
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    17. 31-45 of 63 « 1 2 3 4 5 »
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  2. About Daniël M. de Bruin

    Daniël M. de Bruin

    Daniël M. de Bruin is in the Department of Biomedical Engineering and Physics at the Academic Medical Center Amsterdam, The Netherlands.