1. Dalip Singh Mehta

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    1. Mentioned In 16 Articles

    2. Volumetric analysis of breast cancer tissues using machine learning and swept-source optical coherence tomography

      Volumetric analysis of breast cancer tissues using machine learning and swept-source optical coherence tomography
      In breast cancer, 20%30% of cases require a second surgery because of incomplete excision of malignant tissues. Therefore, to avoid the risk of recurrence, accurate detection of the cancer margin by the clinician or surgeons needs some assistance. In this paper, an automated volumetric analysis of normal and breast cancer tissue is done by a machine learning algorithm to separate them into two classes. The proposed method is based ...
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    3. Deep learning architecture “LightOCT” for diagnostic decision support using optical coherence tomography images of biological samples

      Deep learning architecture “LightOCT” for diagnostic decision support using optical coherence tomography images of biological samples
      Optical coherence tomography (OCT) is being increasingly adopted as a label-free and non-invasive technique for biomedical applications such as cancer and ocular disease diagnosis. Diagnostic information for these tissues is manifest in textural and geometric features of the OCT images which are used by human expertise to interpret and triage. However, it suffers delays due to long process of conventional diagnostic procedure and shortage of human expertise. Here, a custom ...
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    4. Automated high resolution full-field spatial coherence tomography for quantitative phase imaging of human red blood cells

      Automated high resolution full-field spatial coherence tomography for quantitative phase imaging of human red blood cells
      We developed an automated high-resolution full-field spatial coherence tomography (FF-SCT) microscope for quantitative phase imaging that is based on the spatial, rather than the temporal, coherence gating. The Red and Green color laser light was used for finding the quantitative phase images of unstained human red blood cells (RBCs). This study uses morphological parameters of unstained RBCs phase images to distinguish between normal and infected cells. We recorded the single ...
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    5. In vivo classification of human skin burns using machine learning and quantitative features captured by optical coherence tomography

      In vivo classification of human skin burns using machine learning and quantitative features captured by optical coherence tomography
      We report the first fully automated detection of human skin burn injuries in vivo , with the goal of automatic surgical margin assessment based on optical coherence tomography (OCT) images. Our proposed automated procedure entails building a machine-learning-based classifier by extracting quantitative features from normal and burn tissue images recorded by OCT. In this study, 56 samples (28 normal, 28 burned) were imaged by OCT and eight features were extracted. A ...
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    6. Reflection, phase and en -face sectional imaging of scattering objects using quasi-single-shot wide-field optical coherence tomography

      Reflection, phase and en -face sectional imaging of scattering objects using quasi-single-shot wide-field optical coherence tomography
      We report a quasi-single-shot wide-field optical coherence tomography system that enables to measure the reflection, phase and en - face OCT images from the same setup using the glass jig. The jig consisting of a wedge glass substrate and a glue dot is contacted to the tissue surfaces, and the data within glue dot is used to reduce the phase noise of the interference signal. The reconstructed image size of the ...
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    7. Improvement of the dynamic range using background subtraction in single shot wide-field optical coherence tomography

      Improvement of the dynamic range using background subtraction in single shot wide-field optical coherence tomography
      We investigated on the signal in single shot wide-field optical coherence tomographic (SS-WF-OCT) system to improve the dynamic range (DR). The SS-WF-OCT system is based on two-dimensional (2D) polarization Michelson interferometer and superluminescent diode (center wavelength of 842.5nm) as light source. Two-phase-shifted interferograms were acquired simultaneously using a single CCD camera and after subtraction, theen-faceOCT image (area (x) 4.0mm(y) 4.3mm) is obtained using 2D Hilbert transform ...
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    8. High-resolution full-field spatial coherence gated optical tomography using monochromatic light source

      High-resolution full-field spatial coherence gated optical tomography using monochromatic light source
      We demonstrate dispersion free, high-resolution full-field spatial coherence gated optical tomography using spatially incoherent monochromatic light source. Spatial coherence properties of light source were synthesized by means of combining a static diffuser and vibrating multi mode fiber bundle. Due to low spatial coherence of light source, the axial resolution of the system was achieved similar to that of conventional optical coherence tomography which utilizes low temporal coherence. Experimental results of ...
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    9. High-resolution corneal topography and tomography of fish eye using wide-field white light interference microscopy

      High-resolution corneal topography and tomography of fish eye using wide-field white light interference microscopy
      Topography and tomography of fish cornea is reconstructed using high resolution white light interference microscopy. White light interferograms at different depths were recorded by moving the object axially. For each depth position, five phase shifted interferograms were recorded and analyzed. From the reconstructed phase maps, the corneal topography and hence the refractive index was determined and from amplitude images the cross-sectional image of fish cornea was reconstructed. In the present ...
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    10. Quantitative phase imaging of human red blood cells using phase-shifting white light interference microscopy with colour fringe analysis

      Quantitative phase imaging of human red blood cells using phase-shifting white light interference microscopy with colour fringe analysis
      We report quantitative phase imaging of human red blood cells (RBCs) using phase-shifting interference microscopy. Five phase-shifted white light interferograms are recorded using colour charge coupled device camera. White light interferograms were decomposed into red, green, and blue colour components. The phase-shifted interferograms of each colour were then processed by phase-shifting analysis and phase maps for red, green, and blue colours were reconstructed. Wavelength dependent refractive index profiles of RBCs ...
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    11. Tomographic and volumetric reconstruction of composite materials using full-field swept-source optical coherence tomography

      Tomographic and volumetric reconstruction of composite materials using full-field swept-source optical coherence tomography
      We demonstrate tomographic and volumetric reconstruction of composite material using a full-field swept-source optical coherence tomographic (FF-SS-OCT) system. The FF-SS-OCT system is based on a co-axial and common-path optical interferometric system based on Mirau objective lens. By means of sweeping the frequency of the broad-band light source, multiple spectral interferograms are recorded and stacked in the X–Y–λ axes and processed in a computer. Optically sectioned images of the ...
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    12. Transmission Mode Full-Field Swept-Source Optical Coherence Tomography for Simultaneous Amplitude and Quantitative Phase Imaging of Transparent Objects

      Transmission Mode Full-Field Swept-Source Optical Coherence Tomography for Simultaneous Amplitude and Quantitative Phase Imaging of Transparent Objects
      A transmission mode full-field swept-source optical coherence tomographic system is demonstrated for simultaneous amplitude and quantitative phase imaging of transparent objects. The experimental setup consists of a swept-source system, fiber-optic Mach–Zehnder interferometer, and an area detector. By means of sweeping the wavelength of light source, multiple interefrograms were recorded and both amplitude as well as phase images of the multilayer object and onion skin were reconstructed. The main advantages ...
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    13. Simultaneous tomography and topography of silicon integrated circuits using full-fieldswept-source optical coherence tomography

      Abstract. We demonstrate simultaneous tomography and topography of micro-electro-mechanical systems based on silicon integrated circuits using full-field swept-source optical coherence tomography. The optical set-up consists of a swept-source system, a compact Michelson interferometer, and an area detector. The swept-source system comprises a superluminescent diode as a broadband light source in conjunction with an acousto-optic tunable filter as a fast frequency tuning device. By means of sweeping the frequency of the ...
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    14. Simultaneous topography and tomography of latent fingerprints using full-field swept-source optical coherence tomography

      Simultaneous topography and tomography of latent fingerprints using full-field swept-source optical coherence tomography 1 Laser Applications and Holography Laboratory, Instrument Design Development Centre, Indian Institute of Technology Delhi, Hauz Khas, New Delhi-110 016, India 2 Institute for Plasma Research, Bhat, Gandhinagar, 382428, India E-mail: dsmehta@iddc.iitd.ac.in Abstract. We demonstrate simultaneous topography and tomography of latent fingerprints using full-field swept-source opti
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  2. About Dalip Singh Mehta

    Dalip Singh Mehta

    Dalip Singh Mehta is an Associate Professor in the Laser Applications and Holography Laboratory at the Instrument Design Development Center of Indian Institute of Technology Delhi.  Area of Interest: Optical Coherence Tomography (OCT) and 3D-Surface Profilometry, Optical Tweezers; Trapping and Manipulation of Micro-/Nano-Particles, Advanced Optical Imaging Techniques: Biomedical Optics and Biophotonics, Advanced Display Devices and Technologies; LCD's and OLED's, Digital Holography and Applications, Laser Applications & Laser Based NDT Techniques, Advanced Optical Interferometry: Optical Coherence and Quantum Optics, Photonic Bandgap devices, Nanophotonics and Nanometrology.