1. Cornell University

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    1. Mentioned In 81 Articles

    2. Dynamic Contrast Optical Coherence Tomography reveals laminar microvascular hemodynamics in the mouse neocortex in vivo

      Explore ScienceDirect Neurology
      Dynamic Contrast Optical Coherence Tomography reveals laminar microvascular hemodynamics in the mouse neocortex in vivo
      Studies of flow-metabolism coupling often presume that microvessel architecture is a surrogate for blood flow. To test this assumption, we introduce an in vivo Dynamic Contrast Optical Coherence Tomography (DyC-OCT) method to quantify layer-resolved microvascular blood flow and volume across the full depth of the mouse neocortex, where the angioarchitecture has been previously described . First, we cross-validate average DyC-OCT cortical flow against conventional Doppler OCT flow. Next, with laminar DyC-OCT ...
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      Mentions: Cornell University Vivek J. Srinivasan UC Davis

    3. Chip-based frequency comb sources for optical coherence tomography

      Explore OSA | OSA Publishing Ophthalmology
      Chip-based frequency comb sources for optical coherence tomography
      Optical coherence tomography (OCT) is a powerful interferometric imaging technique widely used in medical fields such as ophthalmology, cardiology and dermatology. Superluminescent diodes (SLDs) are widely used as light sources in OCT. Recently integrated chip-based frequency combs have been demonstrated in numerous platforms and the possibility of using these broadband chip-scale combs for OCT has been raised extensively over the past few years. However, the use of these chip-based frequency ...
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      Mentions: Cornell University Columbia University University of Alabama

    5. Correlation between B-scan optical coherence tomography, en face thickness map ring and hyperautofluorescent ring in retinitis pigmentosa patients

      Explore Home - Springer Ophthalmology
      Correlation between B-scan optical coherence tomography, en face thickness map ring and hyperautofluorescent ring in retinitis pigmentosa patients
      Objective To evaluate and compare the B-scan OCT loss of ellipsoid zone, OCT en face thickness map constriction, and hyperautofluorescent ring constriction in RP patients. Methods Retrospective case series study. Forty-eight eyes of 24 RP patients with a parafoveal hyperautofluorescent ring were studied. The diagnosis of RP was established by the presence of rod response impairment and a prevalent decrease of scotopic over photopic responses on electroretinography. The FAF and ...
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      Mentions: Universidade Federal de São Paulo Cornell University Columbia University

    6. Possible Undiagnosed Glaucoma Detected by MultiColor Imaging of Retinal Diseases

      Explore ScienceDirect Ophthalmology
      Possible Undiagnosed Glaucoma Detected by MultiColor Imaging of Retinal Diseases
      Purpose To evaluate for the presence of visible retinal nerve fiber layer (RNFL) defects consistent with undiagnosed glaucoma in MultiColor images (Heidelberg Engineering, Heidelberg, Germany) obtained at clinicians discretion for the diagnosis and management of retinal diseases. Design Retrospective chart review of MultiColor images obtained as part of routine clinical care between December 25, 2013 and June 24, 2014. Images were reviewed by 2 fellowship-trained glaucoma specialists (S.H.V ...
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      Mentions: Heidelberg Engineering Cornell University Duke University

    7. Quantitative reconstruction of time-varying 3D cell forces with traction force optical coherence microscopy

      Explore Nature Publishing Group
      Quantitative reconstruction of time-varying 3D cell forces with traction force optical coherence microscopy
      Cellular traction forces (CTFs) play an integral role in both physiological processes and disease, and are a topic of interest in mechanobiology. Traction force microscopy (TFM) is a family of methods used to quantify CTFs in a variety of settings. State-of-the-art 3D TFM methods typically rely on confocal fluorescence microscopy, which can impose limitations on acquisition speed, volumetric coverage, and temporal sampling or coverage. In this report, we present the ...
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      Mentions: Cornell University Steven G. Adie

    8. Spectral domain optical coherence tomography evaluation of the feline optic nerve and peripapillary retina

      Explore Wiley Online Library Ophthalmology
      Spectral domain optical coherence tomography evaluation of the feline optic nerve and peripapillary retina
      Objective To describe and to establish normative data for the feline optic nerve and peripapillary retina using SD‐OCT (Spectralis HRA+OCT2). Methods Slit‐lamp biomicroscopy and rebound tonometry were performed in seven male‐intact (0.65 0.02 years;4.34 0.33 kg) and seven female‐spayed (0.74 0.03 years; 3.13 0.28 kg) cats. All eyes were pharmacologically dilated with 1% tropicamide prior to ...
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      Mentions: Heidelberg Engineering Cornell University

    9. Chip-based frequency combs sources for optical coherence tomography

      Explore arxiv.org
      Chip-based frequency combs sources for optical coherence tomography
      The Optical coherence tomography (OCT) is a powerful interferometric imaging technique widely used in medical fields such as ophthalmology, cardiology and dermatology, for which footprint and cost are becoming increasingly important. Here we present a platform for miniaturized sources for OCT based on chip-scale lithographically defined microresonators. We show that the proposed platform is compatible with standard commercial spectral domain (SD) OCT systems and enable imaging of human tissue with ...
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      Mentions: Cornell University Columbia University Christine P. Hendon

    11. Compensating spatially dependent dispersion in visible light OCT

      Explore OSA | OSA Publishing
      Compensating spatially dependent dispersion in visible light OCT
      Visible light optical coherence tomography (OCT) has recently emerged in retinal imaging, with claims of micrometer-scale axial resolution and multi-color (sub-band) imaging. Here, we show that the large dispersion of optical glass and aqueous media, together with broad optical bandwidths often used in visible light OCT, compromises both of these claims. To rectify this, we introduce the notion of spatially dependent (i.e., depth and transverse position-dependent) dispersion. We use ...
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      Mentions: Cornell University Vivek J. Srinivasan UC Davis

    13. Optical sensing based on measurements of displacements induced by optical forces in viscoelastic media using phase-sensitive optical coherence tomography

      Explore uspto.gov Patents
      Optical sensing based on measurements of displacements induced by optical forces in viscoelastic media using phase-sensitive optical coherence tomography
      A system for providing optical actuation and optical sensing can include an optical coherence tomography (OCT) device that performs optical imaging of a sample based on optical interferometry from an optical sampling beam interacting with an optical sample and an optical reference beam; an OCT light source to provide an OCT imaging beam into the OCT device which splits the OCT imaging beam into the optical sampling beam and the ...
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      Mentions: Cornell University Steven G. Adie

    14. Feature Of The Week 09/29/2018: Cornell University Researchers Develop New Method for Ultra-Deep, Speckle-Suppressed, Volumetric Optical Coherence Microscopy

      Explore Optical Coherence Tomography News
      Feature Of The Week 09/29/2018: Cornell University Researchers Develop New Method for Ultra-Deep, Speckle-Suppressed, Volumetric Optical Coherence Microscopy
      ...lumetric optical coherence microscopy. For more information see recent Article . Courtesy Steven G. Adie from Cornell University . Multiple scattering is a major barrier that limits the optical imaging depth in scatterin...
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      Mentions: Cornell University Steven G. Adie

    15. Aberration-diverse optical coherence tomography for suppression of multiple scattering and speckle

      Explore OSA | OSA Publishing
      Aberration-diverse optical coherence tomography for suppression of multiple scattering and speckle
      Multiple scattering is a major barrier that limits the optical imaging depth in scattering media. In order to alleviate this effect, we demonstrate aberration-diverse optical coherence tomography (AD-OCT), which exploits the phase correlation between the deterministic signals from single-scattered photons to suppress the random background caused by multiple scattering and speckle. AD-OCT illuminates the sample volume with diverse aberrated point spread functions, and computationally removes these intentionally applied aberrations. After ...
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      Mentions: Cornell University Steven G. Adie

    16. Optical sensing based on measurements of displacements induced by optical scattering forces in viscoelastic media using phase-sensitive optical coherence tomography

      Explore uspto.gov Patents
      Optical sensing based on measurements of displacements induced by optical scattering forces in viscoelastic media using phase-sensitive optical coherence tomography
      Disclosed are devices and techniques based on optical coherence tomography (OCT) technology in combination with optical actuation. A system for providing optical actuation and optical sensing can include an optical coherence tomography (OCT) device that performs optical imaging of a sample based on optical interferometry from an optical sampling beam interacting with an optical sample and an optical reference beam; an OCT light source to provide an OCT imaging beam ...
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      Mentions: Cornell University Steven G. Adie
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  4. About Cornell University

    Cornell University

    Cornell University is a private university located in Ithaca, New York, U.S. Its two medical campuses are in New York City and Education City, Qatar. Cornell is a member of the Ivy League. Cornell was founded in 1865 by Ezra Cornell and Andrew Dickson White as a coeducational, non-sectarian institution where admission was offered irrespective of religion or race. Inaugurated shortly after the American Civil War, its founders intended that the new university would teach and make contributions in all fields of knowledge — from the classics to the sciences and from the theoretical to the applied. Also see Wiel Cornell Medical College.

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