1. Cornell University

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    1. Mentioned In 80 Articles

    2. Chip-based frequency comb sources for optical coherence tomography

      Chip-based frequency comb sources for optical coherence tomography
      Optical coherence tomography (OCT) is a powerful interferometric imaging technique widely used in medical fields such as ophthalmology, cardiology and dermatology. Superluminescent diodes (SLDs) are widely used as light sources in OCT. Recently integrated chip-based frequency combs have been demonstrated in numerous platforms and the possibility of using these broadband chip-scale combs for OCT has been raised extensively over the past few years. However, the use of these chip-based frequency ...
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    3. Correlation between B-scan optical coherence tomography, en face thickness map ring and hyperautofluorescent ring in retinitis pigmentosa patients

      Correlation between B-scan optical coherence tomography, en face thickness map ring and hyperautofluorescent ring in retinitis pigmentosa patients
      Objective To evaluate and compare the B-scan OCT loss of ellipsoid zone, OCT en face thickness map constriction, and hyperautofluorescent ring constriction in RP patients. Methods Retrospective case series study. Forty-eight eyes of 24 RP patients with a parafoveal hyperautofluorescent ring were studied. The diagnosis of RP was established by the presence of rod response impairment and a prevalent decrease of scotopic over photopic responses on electroretinography. The FAF and ...
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    4. Possible Undiagnosed Glaucoma Detected by MultiColor Imaging of Retinal Diseases

      Possible Undiagnosed Glaucoma Detected by MultiColor Imaging of Retinal Diseases
      Purpose To evaluate for the presence of visible retinal nerve fiber layer (RNFL) defects consistent with undiagnosed glaucoma in MultiColor images (Heidelberg Engineering, Heidelberg, Germany) obtained at clinicians discretion for the diagnosis and management of retinal diseases. Design Retrospective chart review of MultiColor images obtained as part of routine clinical care between December 25, 2013 and June 24, 2014. Images were reviewed by 2 fellowship-trained glaucoma specialists (S.H.V ...
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    5. Quantitative reconstruction of time-varying 3D cell forces with traction force optical coherence microscopy

      Quantitative reconstruction of time-varying 3D cell forces with traction force optical coherence microscopy
      Cellular traction forces (CTFs) play an integral role in both physiological processes and disease, and are a topic of interest in mechanobiology. Traction force microscopy (TFM) is a family of methods used to quantify CTFs in a variety of settings. State-of-the-art 3D TFM methods typically rely on confocal fluorescence microscopy, which can impose limitations on acquisition speed, volumetric coverage, and temporal sampling or coverage. In this report, we present the ...
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    6. Spectral domain optical coherence tomography evaluation of the feline optic nerve and peripapillary retina

      Spectral domain optical coherence tomography evaluation of the feline optic nerve and peripapillary retina
      Objective To describe and to establish normative data for the feline optic nerve and peripapillary retina using SD‐OCT (Spectralis HRA+OCT2). Methods Slit‐lamp biomicroscopy and rebound tonometry were performed in seven male‐intact (0.65 0.02 years;4.34 0.33 kg) and seven female‐spayed (0.74 0.03 years; 3.13 0.28 kg) cats. All eyes were pharmacologically dilated with 1% tropicamide prior to ...
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    7. Chip-based frequency combs sources for optical coherence tomography

      Chip-based frequency combs sources for optical coherence tomography
      The Optical coherence tomography (OCT) is a powerful interferometric imaging technique widely used in medical fields such as ophthalmology, cardiology and dermatology, for which footprint and cost are becoming increasingly important. Here we present a platform for miniaturized sources for OCT based on chip-scale lithographically defined microresonators. We show that the proposed platform is compatible with standard commercial spectral domain (SD) OCT systems and enable imaging of human tissue with ...
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    8. Compensating spatially dependent dispersion in visible light OCT

      Compensating spatially dependent dispersion in visible light OCT
      Visible light optical coherence tomography (OCT) has recently emerged in retinal imaging, with claims of micrometer-scale axial resolution and multi-color (sub-band) imaging. Here, we show that the large dispersion of optical glass and aqueous media, together with broad optical bandwidths often used in visible light OCT, compromises both of these claims. To rectify this, we introduce the notion of spatially dependent (i.e., depth and transverse position-dependent) dispersion. We use ...
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    9. Optical sensing based on measurements of displacements induced by optical forces in viscoelastic media using phase-sensitive optical coherence tomography

      Optical sensing based on measurements of displacements induced by optical forces in viscoelastic media using phase-sensitive optical coherence tomography
      A system for providing optical actuation and optical sensing can include an optical coherence tomography (OCT) device that performs optical imaging of a sample based on optical interferometry from an optical sampling beam interacting with an optical sample and an optical reference beam; an OCT light source to provide an OCT imaging beam into the OCT device which splits the OCT imaging beam into the optical sampling beam and the ...
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    10. Feature Of The Week 09/29/2018: Cornell University Researchers Develop New Method for Ultra-Deep, Speckle-Suppressed, Volumetric Optical Coherence Microscopy

      Feature Of The Week 09/29/2018: Cornell University Researchers Develop New Method for Ultra-Deep, Speckle-Suppressed, Volumetric Optical Coherence Microscopy
      ...lumetric optical coherence microscopy. For more information see recent Article . Courtesy Steven G. Adie from Cornell University . Multiple scattering is a major barrier that limits the optical imaging depth in scatterin...
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    11. Aberration-diverse optical coherence tomography for suppression of multiple scattering and speckle

      Aberration-diverse optical coherence tomography for suppression of multiple scattering and speckle
      Multiple scattering is a major barrier that limits the optical imaging depth in scattering media. In order to alleviate this effect, we demonstrate aberration-diverse optical coherence tomography (AD-OCT), which exploits the phase correlation between the deterministic signals from single-scattered photons to suppress the random background caused by multiple scattering and speckle. AD-OCT illuminates the sample volume with diverse aberrated point spread functions, and computationally removes these intentionally applied aberrations. After ...
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    12. Optical sensing based on measurements of displacements induced by optical scattering forces in viscoelastic media using phase-sensitive optical coherence tomography

      Optical sensing based on measurements of displacements induced by optical scattering forces in viscoelastic media using phase-sensitive optical coherence tomography
      Disclosed are devices and techniques based on optical coherence tomography (OCT) technology in combination with optical actuation. A system for providing optical actuation and optical sensing can include an optical coherence tomography (OCT) device that performs optical imaging of a sample based on optical interferometry from an optical sampling beam interacting with an optical sample and an optical reference beam; an OCT light source to provide an OCT imaging beam ...
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    13. Quantitative progression of retinitis pigmentosa by optical coherence tomography angiography

      Quantitative progression of retinitis pigmentosa by optical coherence tomography angiography
      Optical coherence tomography angiography (OCT-A) is a non-invasive alternative to fluorescein angiography that allows for the study of the retinal and choroidal vasculatures. In this retrospective cohort study of 28 patients with retinitis pigmentosa (RP), we used OCT-A to quantify changes in perfusion density, foveal avascular zone (FAZ) area, and choriocapillaris blood flow over time and correlated these variables with ellipsoid zone (EZ) line width and best-corrected visual acuity (BCVA ...
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  2. About Cornell University

    Cornell University

    Cornell University is a private university located in Ithaca, New York, U.S. Its two medical campuses are in New York City and Education City, Qatar. Cornell is a member of the Ivy League. Cornell was founded in 1865 by Ezra Cornell and Andrew Dickson White as a coeducational, non-sectarian institution where admission was offered irrespective of religion or race. Inaugurated shortly after the American Civil War, its founders intended that the new university would teach and make contributions in all fields of knowledge — from the classics to the sciences and from the theoretical to the applied. Also see Wiel Cornell Medical College.