1. Cornell University

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    1. Mentioned In 73 Articles

    3. Compensating spatially dependent dispersion in visible light OCT

      Explore OSA | OSA Publishing
      Compensating spatially dependent dispersion in visible light OCT
      Visible light optical coherence tomography (OCT) has recently emerged in retinal imaging, with claims of micrometer-scale axial resolution and multi-color (sub-band) imaging. Here, we show that the large dispersion of optical glass and aqueous media, together with broad optical bandwidths often used in visible light OCT, compromises both of these claims. To rectify this, we introduce the notion of spatially dependent (i.e., depth and transverse position-dependent) dispersion. We use ...
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      Mentions: Cornell University Vivek J. Srinivasan UC Davis

    5. Optical sensing based on measurements of displacements induced by optical forces in viscoelastic media using phase-sensitive optical coherence tomography

      Explore uspto.gov Patents
      Optical sensing based on measurements of displacements induced by optical forces in viscoelastic media using phase-sensitive optical coherence tomography
      A system for providing optical actuation and optical sensing can include an optical coherence tomography (OCT) device that performs optical imaging of a sample based on optical interferometry from an optical sampling beam interacting with an optical sample and an optical reference beam; an OCT light source to provide an OCT imaging beam into the OCT device which splits the OCT imaging beam into the optical sampling beam and the ...
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      Mentions: Cornell University Steven G. Adie

    6. Feature Of The Week 09/29/2018: Cornell University Researchers Develop New Method for Ultra-Deep, Speckle-Suppressed, Volumetric Optical Coherence Microscopy

      Explore Optical Coherence Tomography News
      Feature Of The Week 09/29/2018: Cornell University Researchers Develop New Method for Ultra-Deep, Speckle-Suppressed, Volumetric Optical Coherence Microscopy
      ...lumetric optical coherence microscopy. For more information see recent Article . Courtesy Steven G. Adie from Cornell University . Multiple scattering is a major barrier that limits the optical imaging depth in scatterin...
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      Mentions: Cornell University Steven G. Adie

    7. Aberration-diverse optical coherence tomography for suppression of multiple scattering and speckle

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      Aberration-diverse optical coherence tomography for suppression of multiple scattering and speckle
      Multiple scattering is a major barrier that limits the optical imaging depth in scattering media. In order to alleviate this effect, we demonstrate aberration-diverse optical coherence tomography (AD-OCT), which exploits the phase correlation between the deterministic signals from single-scattered photons to suppress the random background caused by multiple scattering and speckle. AD-OCT illuminates the sample volume with diverse aberrated point spread functions, and computationally removes these intentionally applied aberrations. After ...
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      Mentions: Cornell University Steven G. Adie

    8. Optical sensing based on measurements of displacements induced by optical scattering forces in viscoelastic media using phase-sensitive optical coherence tomography

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      Optical sensing based on measurements of displacements induced by optical scattering forces in viscoelastic media using phase-sensitive optical coherence tomography
      Disclosed are devices and techniques based on optical coherence tomography (OCT) technology in combination with optical actuation. A system for providing optical actuation and optical sensing can include an optical coherence tomography (OCT) device that performs optical imaging of a sample based on optical interferometry from an optical sampling beam interacting with an optical sample and an optical reference beam; an OCT light source to provide an OCT imaging beam ...
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      Mentions: Cornell University Steven G. Adie

    9. Quantitative progression of retinitis pigmentosa by optical coherence tomography angiography

      Explore Nature Publishing Group Ophthalmology
      Quantitative progression of retinitis pigmentosa by optical coherence tomography angiography
      Optical coherence tomography angiography (OCT-A) is a non-invasive alternative to fluorescein angiography that allows for the study of the retinal and choroidal vasculatures. In this retrospective cohort study of 28 patients with retinitis pigmentosa (RP), we used OCT-A to quantify changes in perfusion density, foveal avascular zone (FAZ) area, and choriocapillaris blood flow over time and correlated these variables with ellipsoid zone (EZ) line width and best-corrected visual acuity (BCVA ...
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      Mentions: Cornell University Columbia University Stanford University

    10. Volumetric optical coherence microscopy with a high space-bandwidth-time product enabled by hybrid adaptive optics

      Explore OSA | OSA Publishing Microscopy
      Volumetric optical coherence microscopy with a high space-bandwidth-time product enabled by hybrid adaptive optics
      Optical coherence microscopy (OCM) is a promising modality for high resolution imaging, but has limited ability to capture large-scale volumetric information about dynamic biological processes with cellular resolution. To enhance the throughput of OCM, we implemented a hybrid adaptive optics (hyAO) approach that combines computational adaptive optics with an intentionally aberrated imaging beam generated via hardware adaptive optics. Using hyAO, we demonstrate the depth-equalized illumination and collection ability of an ...
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      Mentions: Cornell University Steven G. Adie

    11. Photonic force optical coherence elastography for three-dimensional mechanical microscopy

      Explore Nature Publishing Group
      Photonic force optical coherence elastography for three-dimensional mechanical microscopy
      Optical tweezers are an invaluable tool for non-contact trapping and micro-manipulation, but their ability to facilitate high-throughput volumetric microrheology of biological samples for mechanobiology research is limited by the precise alignment associated with the excitation and detection of individual bead oscillations. In contrast, radiation pressure from a low-numerical aperture optical beam can apply transversely localized force over an extended depth range. Here we present photonic force optical coherence elastography (PF-OCE ...
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      Mentions: Cornell University University of Western Australia Steven G. Adie

    12. Optical Coherence Tomography Angiography to Evaluate Ischemia in Diabetic Eyes

      Explore The JAMA Network Ophthalmology
      Optical Coherence Tomography Angiography to Evaluate Ischemia in Diabetic Eyes
      The retinal vasculature consists of a superficial vascular plexus (SVP), an intermediate capillary plexus (ICP), and a deep capillary plexus (DCP). There is also a fourth regional vascular network, the radial peripapillary capillary plexus (RPCP). The RPCP runs in parallel with the nerve fiber layer, the SVP is located within the ganglion cell layer and the deeper plexuses, and the ICP and DCP are above and below the inner nuclear ...
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      Mentions: Cornell University

    13. SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY FINDINGS IN COATS DISEASE

      Explore LWW Online Ophthalmology
      SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY FINDINGS IN COATS DISEASE
      Purpose: To evaluate microstructural retinal abnormalities on spectral domain optical coherence tomography (SD-OCT) imaging of eyes with Coats disease . Methods: This is a multicenter, retrospective study in which SD-OCT images of patients with treatment-naive Coats disease were correlated with clinical examination and visual acuity and, when available, followed longitudinally over time. Results: Macular SD-OCT of 27 eyes with Coats disease revealed intraretinal edema (59%), intraretinal exudates (67%), subretinal fluid (37 ...
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      Mentions: Cornell University

    14. Depth-resolved measurement of optical radiation-pressure forces with optical coherence tomography

      Explore OSA | OSA Publishing
      Depth-resolved measurement of optical radiation-pressure forces with optical coherence tomography
      A weakly focused laser beam can exert sufficient radiation pressure to manipulate microscopic particles over a large depth range. However, depth-resolved continuous measurement of radiation-pressure force profiles over an extended range about the focal plane has not been demonstrated despite decades of research on optical manipulation. Here, we present a method for continuous measurement of axial radiation-pressure forces from a weakly focused beam on polystyrene micro-beads suspended in viscous fluids ...
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      Mentions: Cornell University Steven G. Adie

    15. Photonic force optical coherence elastography for threedimensional mechanical microscopy

      Explore arxiv.org
      Photonic force optical coherence elastography for threedimensional mechanical microscopy
      Optical tweezers are an invaluable tool for non-contact trapping and micro-manipulation, but their ability to facilitate high-throughput volumetric microrheology of biological samples for mechanobiology research is limited by the precise alignment associated with the excitation and detection of individual bead oscillations. In contrast, radiation pressure from a low numerical aperture optical beam can apply transversely localized force over an extended depth range. We propose photonic force optical coherence elastography (PF-OCE ...
      Read Full Article
      Mentions: Cornell University University of Western Australia Steven G. Adie

    16. Hybrid Deep Learning on Single Wide-field Optical Coherence Tomography Scans Accurately Classifies Glaucoma Suspects

      Explore LWW Online Ophthalmology
      Hybrid Deep Learning on Single Wide-field Optical Coherence Tomography Scans Accurately Classifies Glaucoma Suspects
      Purpose: Existing summary statistics based upon optical coherence tomographic (OCT) scans and/or visual fields (VFs) are suboptimal for distinguishing between healthy and glaucomatous eyes in the clinic. This study evaluates the extent to which a hybrid deep learning method (HDLM), combined with a single wide-field OCT protocol, can distinguish eyes previously classified as either healthy suspects or mild glaucoma. Methods: In total, 102 eyes from 102 patients, with or ...
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      Mentions: Cornell University Columbia University Robert Ritch
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  4. About Cornell University

    Cornell University

    Cornell University is a private university located in Ithaca, New York, U.S. Its two medical campuses are in New York City and Education City, Qatar. Cornell is a member of the Ivy League. Cornell was founded in 1865 by Ezra Cornell and Andrew Dickson White as a coeducational, non-sectarian institution where admission was offered irrespective of religion or race. Inaugurated shortly after the American Civil War, its founders intended that the new university would teach and make contributions in all fields of knowledge — from the classics to the sciences and from the theoretical to the applied. Also see Wiel Cornell Medical College.

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