1. Cornell University

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    1. Mentioned In 59 Articles

    2. Hybrid Deep Learning on Single Wide-field Optical Coherence Tomography Scans Accurately Classifies Glaucoma Suspects

      Hybrid Deep Learning on Single Wide-field Optical Coherence Tomography Scans Accurately Classifies Glaucoma Suspects
      Purpose: Existing summary statistics based upon optical coherence tomographic (OCT) scans and/or visual fields (VFs) are suboptimal for distinguishing between healthy and glaucomatous eyes in the clinic. This study evaluates the extent to which a hybrid deep learning method (HDLM), combined with a single wide-field OCT protocol, can distinguish eyes previously classified as either healthy suspects or mild glaucoma. Methods: In total, 102 eyes from 102 patients, with or ...
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    3. Cornell University Receives NIH Grant for Development of Hybrid Adaptive Optics for Multimodal Microscopy Deep in The Mouse Brain

      Cornell University Receives NIH Grant for Development of Hybrid Adaptive Optics for Multimodal Microscopy Deep in The Mouse Brain
      ...rm our ability for large-scale, volumetric recording of mouse brain activity.

      Cornell University Receives a 2017 NIH Grant for $244,625 for Development of Hybrid Adaptive Optics for Multim...

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    4. Space Flight–Associated Neuro-ocular Syndrome

      Space Flight–Associated Neuro-ocular Syndrome
      New and unique physiologic and pathologic systemic and neuro-ocular responses have been documented in astronauts during and after long-duration space flight. Although the precise cause remains unknown, space flightassociated neuro-ocular syndrome (SANS) has been adopted as an appropriate descriptive term. The Space Medicine Operations Division of the US National Aeronautics and Space Administration (NASA) has documented the variable occurrence of SANS in astronauts returning from long-duration space flight on the ...
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    5. Measurement of dynamic cell-induced 3D displacement fields in vitro for traction force optical coherence microscopy

      Measurement of dynamic cell-induced 3D displacement fields in vitro for traction force optical coherence microscopy
      Traction force microscopy (TFM) is a method used to study the forces exerted by cells as they sense and interact with their environment. Cell forces play a role in processes that take place over a wide range of spatiotemporal scales, and so it is desirable that TFM makes use of imaging modalities that can effectively capture the dynamics associated with these processes. To date, confocal microscopy has been the imaging ...
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    6. Label-Free Imaging of Eosinophilic Esophagitis Mouse Models Using Optical Coherence Tomography

      Label-Free Imaging of Eosinophilic Esophagitis Mouse Models Using Optical Coherence Tomography
      Eosinophilic esophagitis (EoE) is an immune-mediated disorder characterized by esophageal inflammation and related structural changes causing symptoms such as feeding difficulties and food impaction. The pathophysiological mechanisms underlying EoE remain poorly understood. Preclinical studies using mouse models have been critical in comprehending human disease mechanisms and associated pathways. In this chapter, we describe an experimental method using a noninvasive label-free optical imaging technique, optical coherence tomography, to characterize the pathophysiological ...
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    7. Acoustic Radiation Force Optical Coherence Elastography : Localized Vs. Wide-Area Perturbation – A Comparison (Thesis)

      Acoustic Radiation Force Optical Coherence Elastography : Localized Vs. Wide-Area Perturbation – A Comparison (Thesis)
      Elastography is a method to image the biomechanical properties of tissues. The experimental setup has a 10 MHz ultrasound transducer (focal length of 5cm and a spot size of 0.3mm localized excitation and unfocused for wide-area excitation) which generates acoustic radiation force (ARF) to perturb the sample and the corresponding mechanical response is imaged with a spectral domain optical coherence tomography (SD-OCT) with a center wavelength of 800 nm ...
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    8. Computational adaptive optics for broadband interferometric tomography of tissues and cells

      Computational adaptive optics for broadband interferometric tomography of tissues and cells
      Adaptive optics (AO) can shape aberrated optical wavefronts to physically restore the constructive interference needed for high-resolution imaging. With access to the complex optical field, however, many functions of optical hardware can be achieved computationally, including focusing and the compensation of optical aberrations to restore the constructive interference required for diffraction-limited imaging performance. Holography, which employs interferometric detection of the complex optical field, was developed based on this connection between ...
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    9. GPU-based computational adaptive optics for volumetric optical coherence microscopy

      GPU-based computational adaptive optics for volumetric optical coherence microscopy
      Optical coherence tomography (OCT) is a non-invasive imaging technique that measures reflectance from within biological tissues. Current higher-NA optical coherence microscopy (OCM) technologies with near cellular resolution have limitations on volumetric imaging capabilities due to the trade-offs between resolution vs. depth-of-field and sensitivity to aberrations. Such trade-offs can be addressed using computational adaptive optics (CAO), which corrects aberration computationally for all depths based on the complex optical field measured by ...
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    10. Three-dimensional spectral domain optical coherence tomography and light microscopy of an intravitreal parasite

      Three-dimensional spectral domain optical coherence tomography and light microscopy of an intravitreal parasite
      Background Various imaging modalities play a role in diagnosing parasitic infections of the eye. We describe the spectral domain optical coherence tomography (SD-OCT) findings of an intravitreal parasite with subsequent evaluation by light microscopy. Findings This is a case report of a 37-year-old Ecuadorian man who presented with uveitic glaucoma and a new floater in his left eye for 1 weeks duration. Full ophthalmic examination revealed an intravitreal parasite. Color ...
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    11. Discrimination of Glaucoma Patients From Healthy Individuals Using Combined Parameters From Spectral-domain Optical Coherence Tomography in an African American Population

      Discrimination of Glaucoma Patients From Healthy Individuals Using Combined Parameters From Spectral-domain Optical Coherence Tomography in an African American Population
      Purpose: To create a multivariable predictive model for glaucoma in an exclusively African American population and to compare the performance of the model with individual structural parameters derived from SD-OCT. Patients and Methods: A total of 103 healthy eyes and 118 glaucomatous eyes of African American patients underwent SD-OCT optic disc and macular scanning. Twenty-seven optic nerve head, retinal nerve fiber layer (RNFL), and ganglion cell parameters were collected. A ...
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  2. About Cornell University

    Cornell University

    Cornell University is a private university located in Ithaca, New York, U.S. Its two medical campuses are in New York City and Education City, Qatar. Cornell is a member of the Ivy League. Cornell was founded in 1865 by Ezra Cornell and Andrew Dickson White as a coeducational, non-sectarian institution where admission was offered irrespective of religion or race. Inaugurated shortly after the American Civil War, its founders intended that the new university would teach and make contributions in all fields of knowledge — from the classics to the sciences and from the theoretical to the applied. Also see Wiel Cornell Medical College.