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    1. Mentioned In 88 Articles

    2. Visibility of microvessels in Optical Coherence Tomography Angiography depends on angular orientation

      Explore Wiley Online Library Ophthalmology
      Visibility of microvessels in Optical Coherence Tomography Angiography depends on angular orientation
      OCT Angiography (OCTA) is a widespread tool for depth‐resolved imaging of chorioretinal vasculature with single microvessel resolution. To improve the clinical interpretation of OCTA, the conditions affecting visualization of microvessels must be defined. Here we inject a scattering plasma tracer (Intralipid) during OCTA imaging of the anesthetized rat eye. In the retina, we find that interlaminar (vertical) vessels that connect laminae have one‐fourth to one‐third the OCTA ...
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      Mentions: Cornell University Vivek J. Srinivasan UC Davis

    3. Obesity‐Associated Adipose Stromal Cells Promote Breast Cancer Invasion through Direct Cell Contact and ECM Remodeling

      Explore Wiley Online Library
      Obesity‐Associated Adipose Stromal Cells Promote Breast Cancer Invasion through Direct Cell Contact and ECM Remodeling
      Obesity increases the risk and worsens the prognosis for breast cancer due, in part, to altered adipose stromal cell (ASC) behavior. Whether ASCs from obese individuals increase migration of breast cancer cells relative to their lean counterparts, however, remains unclear. To test this connection, multicellular spheroids composed of MCF10A‐derived tumor cell lines of varying malignant potential and lean or obese ASCs are embedded into collagen scaffolds mimicking the elastic ...
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      Mentions: Cornell University Steven G. Adie

    4. Optical Coherence Tomography Findings in the Junctional Scotoma of Traquair

      Explore LWW Online Neurology , Ophthalmology
      Optical Coherence Tomography Findings in the Junctional Scotoma of Traquair
      A 43-year-old woman presented with a right-sided visual field defect in the right eye. The visual acuity was normal and there was a right relative afferent pupillary defect. Formal visual field testing revealed a junctional scotoma of Traquair. The fundus examination showed optic atrophy in the right eye and optical coherence tomography demonstrated unilateral band atrophy. Neuroimaging revealed a sellar and suprasellar cystic pituitary adenoma for which she underwent a ...
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      Mentions: Cornell University University of Texas Medical Branch University of Iowa

    5. The Present and Future of Optical Imaging Technologies in the Clinic: Diagnosis and Therapy

      Explore Home - Springer
      The Present and Future of Optical Imaging Technologies in the Clinic: Diagnosis and Therapy
      Medical techniques based upon optical imaging technologies are important tools in clinical practice. The use of optical imaging in medical diagnosis is well established, and a large array of techniques are in current use, such as white light endoscopy, autofluorescence imaging, and optical coherence tomography. The applications of these techniques are expanding, and newer imaging technologies are becoming available to address problems and limitations associated with existing methods. Beyond diagnostics ...
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      Mentions: Cornell University

    7. Computed optical coherence microscopy of mouse brain ex vivo

      Explore SPIE Digital Library Microscopy , Neurology
      Computed optical coherence microscopy of mouse brain ex vivo
      The compromise between lateral resolution and usable imaging depth range is a bottleneck for optical coherence tomography (OCT). Existing solutions for optical coherence microscopy (OCM) suffer from either large data size and long acquisition time or a nonideal point spread function. We present volumetric OCM of mouse brain ex vivo with a large depth coverage by leveraging computational adaptive optics (CAO) to significantly reduce the number of OCM volumes that ...
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      Mentions: Cornell University Steven G. Adie

    8. OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY DETECTS SUBCLINICAL RADIAL PERIPAPILLARY CAPILLARY DENSITY REDUCTION AFTER PLAQUE RADIOTHERAPY FOR CHOROIDAL MELANOMA

      Explore LWW Online Ophthalmology
      OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY DETECTS SUBCLINICAL RADIAL PERIPAPILLARY CAPILLARY DENSITY REDUCTION AFTER PLAQUE RADIOTHERAPY FOR CHOROIDAL MELANOMA
      Purpose: To evaluate radial peripapillary capillary density (RPCD) in irradiated eyes without radiation papillopathy clinically. Methods: Patients treated with plaque radiotherapy for unilateral choroidal melanoma without radiation papillopathy clinically received optical coherence tomography and optical coherence tomography angiography imaging at 12- to 24-month follow-up. Comparison of RPCD globally and meridian closest to plaque and meridian farthest to plaque of irradiated versus nonirradiated eyes was performed. Results: Mean age was 55 ...
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      Mentions: Cornell University Thomas Jefferson University Carol L. Shields

    9. Dynamic Contrast Optical Coherence Tomography reveals laminar microvascular hemodynamics in the mouse neocortex in vivo

      Explore ScienceDirect Neurology
      Dynamic Contrast Optical Coherence Tomography reveals laminar microvascular hemodynamics in the mouse neocortex in vivo
      Studies of flow-metabolism coupling often presume that microvessel architecture is a surrogate for blood flow. To test this assumption, we introduce an in vivo Dynamic Contrast Optical Coherence Tomography (DyC-OCT) method to quantify layer-resolved microvascular blood flow and volume across the full depth of the mouse neocortex, where the angioarchitecture has been previously described . First, we cross-validate average DyC-OCT cortical flow against conventional Doppler OCT flow. Next, with laminar DyC-OCT ...
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      Mentions: Cornell University Vivek J. Srinivasan UC Davis

    10. Chip-based frequency comb sources for optical coherence tomography

      Explore OSA | OSA Publishing Ophthalmology
      Chip-based frequency comb sources for optical coherence tomography
      Optical coherence tomography (OCT) is a powerful interferometric imaging technique widely used in medical fields such as ophthalmology, cardiology and dermatology. Superluminescent diodes (SLDs) are widely used as light sources in OCT. Recently integrated chip-based frequency combs have been demonstrated in numerous platforms and the possibility of using these broadband chip-scale combs for OCT has been raised extensively over the past few years. However, the use of these chip-based frequency ...
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      Mentions: Joseph A. Izatt Cornell University Columbia University

    12. Correlation between B-scan optical coherence tomography, en face thickness map ring and hyperautofluorescent ring in retinitis pigmentosa patients

      Explore Home - Springer Ophthalmology
      Correlation between B-scan optical coherence tomography, en face thickness map ring and hyperautofluorescent ring in retinitis pigmentosa patients
      Objective To evaluate and compare the B-scan OCT loss of ellipsoid zone, OCT en face thickness map constriction, and hyperautofluorescent ring constriction in RP patients. Methods Retrospective case series study. Forty-eight eyes of 24 RP patients with a parafoveal hyperautofluorescent ring were studied. The diagnosis of RP was established by the presence of rod response impairment and a prevalent decrease of scotopic over photopic responses on electroretinography. The FAF and ...
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      Mentions: Universidade Federal de São Paulo Cornell University Columbia University

    13. Possible Undiagnosed Glaucoma Detected by MultiColor Imaging of Retinal Diseases

      Explore ScienceDirect Ophthalmology
      Possible Undiagnosed Glaucoma Detected by MultiColor Imaging of Retinal Diseases
      Purpose To evaluate for the presence of visible retinal nerve fiber layer (RNFL) defects consistent with undiagnosed glaucoma in MultiColor images (Heidelberg Engineering, Heidelberg, Germany) obtained at clinicians discretion for the diagnosis and management of retinal diseases. Design Retrospective chart review of MultiColor images obtained as part of routine clinical care between December 25, 2013 and June 24, 2014. Images were reviewed by 2 fellowship-trained glaucoma specialists (S.H.V ...
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      Mentions: Heidelberg Engineering Cornell University Duke University

    14. Quantitative reconstruction of time-varying 3D cell forces with traction force optical coherence microscopy

      Explore Nature Publishing Group
      Quantitative reconstruction of time-varying 3D cell forces with traction force optical coherence microscopy
      Cellular traction forces (CTFs) play an integral role in both physiological processes and disease, and are a topic of interest in mechanobiology. Traction force microscopy (TFM) is a family of methods used to quantify CTFs in a variety of settings. State-of-the-art 3D TFM methods typically rely on confocal fluorescence microscopy, which can impose limitations on acquisition speed, volumetric coverage, and temporal sampling or coverage. In this report, we present the ...
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      Mentions: Cornell University Steven G. Adie

    15. Spectral domain optical coherence tomography evaluation of the feline optic nerve and peripapillary retina

      Explore Wiley Online Library Ophthalmology
      Spectral domain optical coherence tomography evaluation of the feline optic nerve and peripapillary retina
      Objective To describe and to establish normative data for the feline optic nerve and peripapillary retina using SD‐OCT (Spectralis HRA+OCT2). Methods Slit‐lamp biomicroscopy and rebound tonometry were performed in seven male‐intact (0.65 0.02 years;4.34 0.33 kg) and seven female‐spayed (0.74 0.03 years; 3.13 0.28 kg) cats. All eyes were pharmacologically dilated with 1% tropicamide prior to ...
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      Mentions: Heidelberg Engineering Cornell University

    16. Chip-based frequency combs sources for optical coherence tomography

      Explore arxiv.org
      Chip-based frequency combs sources for optical coherence tomography
      The Optical coherence tomography (OCT) is a powerful interferometric imaging technique widely used in medical fields such as ophthalmology, cardiology and dermatology, for which footprint and cost are becoming increasingly important. Here we present a platform for miniaturized sources for OCT based on chip-scale lithographically defined microresonators. We show that the proposed platform is compatible with standard commercial spectral domain (SD) OCT systems and enable imaging of human tissue with ...
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      Mentions: Cornell University Columbia University Christine P. Hendon
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  4. About Cornell University

    Cornell University

    Cornell University is a private university located in Ithaca, New York, U.S. Its two medical campuses are in New York City and Education City, Qatar. Cornell is a member of the Ivy League. Cornell was founded in 1865 by Ezra Cornell and Andrew Dickson White as a coeducational, non-sectarian institution where admission was offered irrespective of religion or race. Inaugurated shortly after the American Civil War, its founders intended that the new university would teach and make contributions in all fields of knowledge — from the classics to the sciences and from the theoretical to the applied. Also see Wiel Cornell Medical College.

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