1. Congwu Du

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    1-13 of 13
    1. Mentioned In 13 Articles

    2. Cerebral capillary flow imaging by wavelength‐division‐multiplexing swept‐source optical Doppler tomography

      Cerebral capillary flow imaging by wavelength‐division‐multiplexing swept‐source optical Doppler tomography
      Swept‐source optical coherence tomography has demonstrated the unique advantages for fast imaging rate and long imaging distance, however, limited axial resolution and complex phase noises restrict swept‐source optical coherence Doppler tomography (SS‐ODT) for quantitative capillary blood flow imaging in the deep cortices. Here, the wavelength‐division‐multiplexing optical Doppler tomography (WDM‐ODT) method, which divides a single interferogram into multiple phase‐correlated interferograms, is proposed to effectively ...
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    3. Volumetric Doppler angle correction for ultrahigh-resolution optical coherence Doppler tomography

      Volumetric Doppler angle correction for ultrahigh-resolution optical coherence Doppler tomography
      Ultrahigh-resolution optical coherence Doppler tomography (ODT) demonstrates great potential for quantitative blood flow imaging owing to its large field of view and capillary resolution. However, ODT only detects the axial flow velocity and requires Doppler angle correction to retrieve the absolute velocity. Although methods for Doppler angle tracking of single or few large vessels have been reported, a method that enables angle correction of the entire 3D microvascular networks remains ...
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    4. High-speed swept source optical coherence Doppler tomography for deep brain microvascular imaging

      High-speed swept source optical coherence Doppler tomography for deep brain microvascular imaging
      Noninvasive microvascular imaging using optical coherence Doppler tomography (ODT) has shown great promise in brain studies; however, high-speed microcirculatory imaging in deep brain remains an open quest. A high-speed 1.3m swept-source ODT (SS-ODT) system is reported which was based on a 200kHz vertical-cavity-surface-emitting laser. Phase errors induced by sweep-trigger desynchronization were effectively reduced by spectral phase encoding and instantaneous correlation among the A-scans. Phantom studies have revealed a significant ...
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    5. State University of New York Stony Brook Received NIH Grant for Optical Platform to Image Neuronal And Visual Effects of Cocaine In Awake Rodents

      State University of New York Stony Brook Received NIH Grant for Optical Platform to Image Neuronal And Visual Effects of Cocaine In Awake Rodents
      ...ical Platform to Image Neuronal And Visual Effects of Cocaine In Awake Rodents. The principal investigator is Congwu Du. The program began in 2016 and ends in 2018. Below is a summary of the propose work. The medial pre...
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    6. Ultrasensitive detection of 3D cerebral microvascular network dynamics in vivo

      Ultrasensitive detection of 3D cerebral microvascular network dynamics in vivo
      Despite widespread applications of multiphoton microscopy in microcirculation, its small field of view and inability to instantaneously quantify cerebral blood flow velocity (CBFv) in vascular networks limit its utility in investigating the heterogeneous responses to brain stimulations. Optical Doppler tomography (ODT) provides 3D images of CBFv networks, but it suffers poor sensitivity for measuring capillary flows. Here we report on a new method, contrast-enhanced ODT with Intralipid that significantly improves ...
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    7. Optical coherence Doppler tomography for quantitative cerebral blood flow imaging

      Optical coherence Doppler tomography for quantitative cerebral blood flow imaging
      Optical coherence Doppler tomography (ODT) is a promising neurotechnique that permits 3D imaging of the cerebral blood flow (CBF) network; however, quantitative CBF velocity (CBFv) imaging remains challenging. Here we present a simple phase summation method to enhance slow capillary flow detection sensitivity without sacrificing dynamic range for fast flow and vessel tracking to improve angle correction for absolute CBFv quantification. Flow phantom validation indicated that the CBFv quantification accuracy ...
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    8. Optical detection of brain function: simultaneous imaging of cerebral vascular response, tissue metabolism, and cellular activity in vivo

      Optical detection of brain function: simultaneous imaging of cerebral vascular response, tissue metabolism, and cellular activity in vivo
      ...unction: simultaneous imaging of cerebral vascular response, tissue metabolism, and cellular activity in vivo Congwu Du^1, Yingtian Pan^2, ^1Medical Department, Brookhaven National Laboratory, Upton, NY 11973-5000, USA ^...
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    9. Optical coherence Doppler tomography quantifies laser speckle contrast imaging for blood flow imaging in the rat cerebral cortex

      Optical coherence Doppler tomography quantifies laser speckle contrast imaging for blood flow imaging in the rat cerebral cortex
      A dual-imaging modality is demonstrated for high-resolution quantitative imaging of local cerebral blood flow in the rat cortex by combining simultaneous spectral-domain Doppler optical coherence tomography (SDOCT) and full-field laser speckle contrast imaging (LSCI). Preliminary studies in tissue flow phantom and cocaine-induced cerebral blood flow changes indicated that by correlating coregistered cortical arterial blood flow, the relative measurement of flow changes by LSCI could be accurately calibrated by the absolute ...
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  2. About Congwu Du

    Congwu Du

    Congwu Du is from Stony Brook University.