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    1. Mentioned In 320 Articles

    2. Vitamin A deficiency and the retinal “double carrot” sign with optical coherence tomography

      Vitamin A deficiency and the retinal “double carrot” sign with optical coherence tomography
      Background Spectral-domain optical coherence tomography (SD-OCT) and full-field electroretinography (ERG) allow retinal assessment with vitamin A deficiency (VAD). Using SD-OCT, this study aimed to characterize and follow a novel retinal abnormality in patients with VAD and intramuscular supplementation. Methods Patients with VAD were retrospectively reviewed, including SD-OCT and electroretinography. Results Three patients had VAD following bariatric or colon surgery and varying supplementation. All had nyctalopia, extinguished scotopic rod-specific function with ...
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    3. Computational Fractional Flow Reserve From Coronary Computed Tomography Angiography-Optical Coherence Tomography Fusion Images in Assessing Functionally Significant Coronary Stenosis

      Computational Fractional Flow Reserve From Coronary Computed Tomography Angiography-Optical Coherence Tomography Fusion Images in Assessing Functionally Significant Coronary Stenosis
      Background: Coronary computed tomography angiography (CTA) and optical coherence tomography (OCT) provide additional functional information beyond the anatomy by applying computational fluid dynamics (CFD). This study sought to evaluate a novel approach for estimating computational fractional flow reserve (FFR) from coronary CTA-OCT fusion images. Methods: Among patients who underwent coronary CTA, 148 patients who underwent both pressure wire-based FFR measurement and OCT during angiography to evaluate intermediate stenosis in the ...
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    4. Advances in OCT Imaging in Myopia and Pathologic Myopia

      Advances in OCT Imaging in Myopia and Pathologic Myopia
      Advances in imaging with optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA) technology, including the development of swept source OCT/OCTA, widefield or ultra-widefield systems, have greatly improved the understanding, diagnosis, and treatment of myopia and myopia-related complications. Anterior segment OCT is useful for imaging the anterior segment of myopes, providing the basis for implantable collamer lens optimization, or detecting intraocular lens decentration in high myopic patients. OCT ...
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    5. Classifying breast cancer in ultrahigh-resolution optical coherence tomography images using convolutional neural networks

      Classifying breast cancer in ultrahigh-resolution optical coherence tomography images using convolutional neural networks
      Optical coherence tomography (OCT) is being investigated in breast cancer diagnostics as a real-time histology evaluation tool. We present a customized deep convolutional neural network (CNN) for classification of breast tissues in OCT B-scans. Images of human breast samples from mastectomies and breast reductions were acquired using a custom ultrahigh-resolution OCT system with 2.72 m axial resolution and 5.52 m lateral resolution. The network achieved 96.7% accuracy ...
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    6. Intravascular Imaging to Guide Percutaneous Coronary Intervention Will Be Mandatory Soon

      Intravascular Imaging to Guide Percutaneous Coronary Intervention Will Be Mandatory Soon
      Intravascular ultrasound (IVUS) or optical coherence tomography provides superior information to coronary angiography, including cross-sectional true vessel size, amount of calcification, distribution of plaque to inform stent landing zone, stent expansion, and stent edge dissection or uncovered disease, which have been well known as key metrics in percutaneous coronary intervention avoiding future stent failure. 1 Complex lesion morphology is typically defined as an unprotected left main lesion, severely calcified lesion ...
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    7. Thin-Cap Fibroatheroma Rather Than Any Lipid Plaques Increases the Risk of Cardiovascular Events in Diabetic Patients: Insights From the COMBINE OCT–FFR Trial

      Thin-Cap Fibroatheroma Rather Than Any Lipid Plaques Increases the Risk of Cardiovascular Events in Diabetic Patients: Insights From the COMBINE OCT–FFR Trial
      Background: Autopsy studies have established that thin-cap fibroatheromas (TCFAs) are the most frequent cause of fatal coronary events. In living patients, optical coherence tomography (OCT) has sufficient resolution to accurately differentiate TCFA from thick-cap fibroatheroma (ThCFA) and not lipid rich plaque (non-LRP). However, the impact of OCT-detected plaque phenotype of nonischemic lesions on future adverse events remains unknown. Therefore, we studied the natural history of OCT-detected TCFA, ThCFA, and non-LRP ...
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    8. Detection of Early Glaucomatous Damage: Performance of Summary Statistics From Optical Coherence Tomography and Perimetry

      Detection of Early Glaucomatous Damage: Performance of Summary Statistics From Optical Coherence Tomography and Perimetry
      Purpose: To evaluate the diagnostic performance of optical coherence tomography (OCT) and visual field (VF) summary statistics (metrics) that are available in OCT and VF reports. Methods: OCT disc and macular scans and 24-2 and 10-2 VFs were obtained from 56 healthy control (HC) eyes/participants and 61 eyes/patients with 24-2 mean deviation of better than -6 dB. All metrics were obtained from OCT radial, circle, and posterior pole ...
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    9. The OCT RNFL Probability Map and Artifacts Resembling Glaucomatous Damage

      The OCT RNFL Probability Map and Artifacts Resembling Glaucomatous Damage
      Purpose: The purpose of this study was to improve the diagnostic ability of the optical coherence tomography (OCT) retinal nerve fiber layer (RNFL) probability (p-) map by understanding the frequency and pattern of artifacts seen on the p-maps of healthy control (HC) eyes resembling glaucomatous damage. Methods: RNFL p-maps were generated from wide-field OCT cube scans of 2 groups of HC eyes, 200 from a commercial normative group (HC-norm) and ...
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    10. Rationale and Development of an OCT-Based Method for Detection of Glaucomatous Optic Neuropathy

      Rationale and Development of an OCT-Based Method for Detection of Glaucomatous Optic Neuropathy
      A specific, sensitive and intersubjectively verifiable definition of disease for clinical care and research remains an important unmet need in the field of glaucoma. Using an iterative, consensus-building approach and employing pilot data, an optical coherence tomography (OCT)-based method to aid in the detection of glaucomatous optic neuropathy was sought to address this challenge. To maximize the chance of success, we utilized all available information from the OCT circle ...
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    11. Detecting glaucoma with only OCT: Implications for the clinic, research, screening, and AI development

      Detecting glaucoma with only OCT: Implications for the clinic, research, screening, and AI development
      A method for detecting glaucoma based only on optical coherence tomography (OCT) is of potential value for routine clinical decisions, for inclusion criteria for research studies and trials, for large-scale clinical screening, as well as for the development of artificial intelligence (AI) decision models. Recent work suggests that the OCT probability (p-) maps, also known as deviation maps, can play a key role in an OCT-based method. However, artifacts seen ...
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    12. Using volumetric optical coherence tomography to achieve spatially resolved organ of Corti vibration measurements

      Using volumetric optical coherence tomography to achieve spatially resolved organ of Corti vibration measurements
      Optical coherence tomography (OCT) has become a powerful tool for measuring vibrations within the organ of Corti complex (OCC) in cochlear mechanics experiments. However, the one-dimensional nature of OCT measurements, combined with experimental and anatomical constraints, make these data ambiguous: Both the relative positions of measured structures and their orientation relative to the direction of measured vibrations are not known a priori . We present a method by which these measurement ...
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    13. Comparisons Among Optical Coherence Tomography and Fundus Autofluorescence Modalities as Measurements of Atrophy in ABCA4-Associated Disease

      Comparisons Among Optical Coherence Tomography and Fundus Autofluorescence Modalities as Measurements of Atrophy in ABCA4-Associated Disease
      Purpose: In ABCA4-associated retinopathy, central atrophy was assessed by spectral domain optical coherence tomography (SD-OCT) and by short-wavelength (SW-AF) and near-infrared (NIR-AF) autofluorescence. Methods: Patients exhibited a central atrophic lesion characterized by hypoautofluorescence (hypoAF) surrounded either by hyperautofluorescent (hyperAF) rings in both AF images (group 1, 4 patients); or a hyperAF ring in SW-AF but not in NIR-AF images (group 2, 11 patients); or hyperAF rings in neither AF images ...
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    14. Rise of the Academic Entrepreneur

      Rise of the Academic Entrepreneur
      Looking for innovative drug delivery systems? Maybe expansive cell growth bioreactors? How about revolutionary gas sensing technology? With just 10 minutes in the spotlight, 10 Columbia Engineering startups recently offered up an array of incredible ventures with industry-altering and even world-alteringpotential. Thirty groups of enterprising engineers, scientists, medical professionals, and other faculty had the chance to charm close to 100 investing firms for Columbia Technology Ventures (CTV) annual Pitch Day ...
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    15. Salicylate-induced changes in organ of Corti vibrations

      Salicylate-induced changes in organ of Corti vibrations
      Intra organ of Corti (OC) vibrations differ from those measured at the basilar membrane (BM), with higher amplitudes and a wide-band nonlinearity extending well below a regions best frequency. The vibrations are boosted by the cochlear amplifier, the active processes within the mammalian hearing organ, and are thus sensitive to metabolic or pharmacological manipulation. We introduced salicylate, a known blocker of outer hair cell (OHC) based electromotility, into the perilymphatic ...
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    16. Intravascular Ultrasound–Derived Calcium Score to Predict Stent Expansion in Severely Calcified Lesions | Circulation: Cardiovascular Interventions

      Intravascular Ultrasound–Derived Calcium Score to Predict Stent Expansion in Severely Calcified Lesions | Circulation: Cardiovascular Interventions
      ...o nonchronic total occlusion native coronary artery lesion from 2011 to 2019 at NewYork-Presbyterian Hospital/Columbia University Irving Medical Center, 3036 lesions with a maximum superficial calcium angle ≤270° (78.6% ...
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    17. 1-15 of 320 1 2 3 4 ... 20 21 22 »
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  2. About Columbia University

    Columbia University

    Columbia University.  From its beginnings in a schoolhouse in lower Manhattan, Columbia University has grown to encompass two principal campuses: the historic, neoclassical campus in the Morningside Heights neighborhood and the modern Medical Center further uptown, in Washington Heights. Today, Columbia is one of the top academic and research institutions in the world, conducting pathbreaking research in medicine, science, the arts, and the humanities. It includes three undergraduate schools, thirteen graduate and professional schools, and a school of continuing education.