1. Columbia University

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    1. Mentioned In 174 Articles

    2. Characteristics of Early Versus Late In-Stent Restenosis in Second- Generation Drug-Eluting Stents: An Optical Coherence Tomography Study

      Characteristics of Early Versus Late In-Stent Restenosis in Second- Generation Drug-Eluting Stents: An Optical Coherence Tomography Study
      Aims: In-stent restenosis (ISR) is an important cause of DES failure and target vessel revascularization. We evaluated differences between early and late-presenting restenosis in second-generation drug-eluting stents (DES) using optical coherence tomography (OCT). Methods and results: Overall, 171 cases of second-generation DES ISR with a follow-up OCT minimum lumen area 3.0mm2 were included; 33.3% of patients (n=57) had early ISR; and 67.7% (n=114) had late ...
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    3. Phase-noise analysis of swept-source optical coherence tomography systems

      Phase-noise analysis of swept-source optical coherence tomography systems
      We propose a new model to characterize the phase noise in swept-source optical coherence tomography (SS-OCT). The new model explicitly incorporates scanning variability, timing jitter, and sample location in addition to intensity noise (shot noise). The model was analyzed and validated by using both Monte Carlo methods and experiments. We suggest that the proposed model can be used as a guideline for future SS-OCT experimental designs.
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    4. Is quantitative coronary angiography reliable in assessing the late lumen loss of the everolimus eluting bioresorbable polylactide scaffold in comparison with the cobalt chromium metallic stent?

      Is quantitative coronary angiography reliable in assessing the late lumen loss of the everolimus eluting bioresorbable polylactide scaffold in comparison with the cobalt chromium metallic stent?
      Aims: Immediately after stent/scaffold implantation, quantitative coronary angiography (QCA) with respect to optical coherence tomography (OCT) more severely underestimates the lumen diameter (LD) in Absorb than in XIENCE. This OCT-QCA discrepancy has not been evaluated at long-term follow-up. The present study aimed to assess the accuracy of QCA with reference to OCT in Absorb as compared to XIENCE.
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    5. Optical Coherence Tomography and Glaucoma Progression: A Comparison of a Region of Interest Approach to Average Retinal Nerve Fiber Layer Thickness

      Optical Coherence Tomography and Glaucoma Progression: A Comparison of a Region of Interest Approach to Average Retinal Nerve Fiber Layer Thickness
      PURPOSE To determine whether the change in the retinal nerve fiber layer (RNFL) thickness in a region of interest (ROI) is a better measure of glaucoma progression than the change in average circumpapillary (cp) RNFL thickness. METHODS Disc cube scans were obtained with frequency domain optical coherence tomography from 60 eyes of 60 patients (age, 61.712.7 y) with early or suspected glaucoma and controlled intraocular pressure. The average ...
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    6. Automated fiber tracking and tissue characterization of the anterior cruciate ligament with optical coherence tomography

      Automated fiber tracking and tissue characterization of the anterior cruciate ligament with optical coherence tomography
      The directionality of collagen fibers across the anterior cruciate ligament (ACL) as well as the insertion of this key ligament into bone are important for understanding the mechanical integrity and functionality of this complex tissue. Quantitative analysis of three-dimensional fiber directionality is of particular interest due to the physiological, mechanical, and biological heterogeneity inherent across the ACL-to-bone junction, the behavior of the ligament under mechanical stress, and the usefulness of ...
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    7. Ex vivo visualization of human ciliated epithelium and quantitative analysis of induced flow dynamics by using optical coherence tomography

      Ex vivo visualization of human ciliated epithelium and quantitative analysis of induced flow dynamics by using optical coherence tomography
      Background and Objective Cilia-driven mucociliary clearance is an important self-defense mechanism of great clinical importance in pulmonary research. Conventional light microscopy possesses the capability to visualize individual cilia and its beating pattern but lacks the throughput to assess the global ciliary activities and flow dynamics. Optical coherence tomography (OCT), which provides depth-resolved cross-sectional images, was recently introduced to this area. Materials and Methods Fourteen de-identified human tracheobronchial tissues are directly ...
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    8. Characterization of ventricular endomyocardial tissue using optical coherence tomography

      Characterization of ventricular endomyocardial tissue using optical coherence tomography
      We present an initial study to describe the potential of optical coherence tomography (OCT) for characterizing endomyocardial tissue. We obtained ventricular OCT images from 15 fresh human hearts. Layer thickness measurements and texture features were extracted from volumetric datasets with endocardial thickening, normal myocardium, myocardium with interstitial fibrosis, normal endocardium, and adipose tissue. Within our datasets, we observed that the thickness of endocardium was not different within samples with normal ...
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    9. Medical Imaging Innovator Christine Hendon Wins Presidential Honor

      Medical Imaging Innovator Christine Hendon Wins Presidential Honor
      Christine Hendon , assistant professor of electrical engineering at Columbia Engineering , has won the Presidential Early Career Award (PECASE), the highest honor the U.S. government gives to young scientists and engineers. Hendon, who develops innovative medical imaging instruments for use in surgery and breast cancer detection, is one of 102 researchers from across the nation named by President Obama on January 9. I congratulate these outstanding scientists and engineers on ...
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    10. Optical Coherence Tomography (OCT) Intravascular Ultrasound (IVUS) Dual Imaging

      Optical Coherence Tomography (OCT) Intravascular Ultrasound (IVUS) Dual Imaging
      Both intravascular ultrasound (IVUS) and optical coherence tomography (OCT) are standardly used and have been extensively studied separately to guide percutaneous coronary intervention and improve long-term outcomes. In this study, the investigators aim to directly compare high-definition IVUS images to OCT in the same patients to determine the differences between each modality as they relate to imaging coronary pathology, with the goal of determining which modality is most appropriate in ...
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    11. Collagen Fiber Orientation and Dispersion in the Upper Cervix of Non-Pregnant and Pregnant Wome

      Collagen Fiber Orientation and Dispersion in the Upper Cervix of Non-Pregnant and Pregnant Wome
      The structural integrity of the cervix in pregnancy is necessary for carrying a pregnancy until term, and the organization of human cervical tissue collagen likely plays an important role in the tissues structural function. Collagen fibers in the cervical extracellular matrix exhibit preferential directionality, and this collagen network ultrastructure is hypothesized to reorient and remodel during cervical softening and dilation at time of parturition. Within the cervix, the upper half ...
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    12. ILUMIEN III Clinical Trial Results from St. Jude Medical Demonstrate Important Findings with Advanced Intravascular Imaging Technology

      ILUMIEN III Clinical Trial Results from St. Jude Medical Demonstrate Important Findings with Advanced Intravascular Imaging Technology
      ...ar research and education at the Center for Interventional Vascular Therapy at New York Presbyterian Hospital/Columbia University Medical Center and co-director of medical research and Education at the Cardiovascular Res...
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    13. 1-15 of 174 1 2 3 4 ... 10 11 12 »
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  2. About Columbia University

    Columbia University

    Columbia University.  From its beginnings in a schoolhouse in lower Manhattan, Columbia University has grown to encompass two principal campuses: the historic, neoclassical campus in the Morningside Heights neighborhood and the modern Medical Center further uptown, in Washington Heights. Today, Columbia is one of the top academic and research institutions in the world, conducting pathbreaking research in medicine, science, the arts, and the humanities. It includes three undergraduate schools, thirteen graduate and professional schools, and a school of continuing education.