1. Columbia University

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    1. Mentioned In 236 Articles

    2. Correlation between B-scan optical coherence tomography, en face thickness map ring and hyperautofluorescent ring in retinitis pigmentosa patients

      Correlation between B-scan optical coherence tomography, en face thickness map ring and hyperautofluorescent ring in retinitis pigmentosa patients
      Objective To evaluate and compare the B-scan OCT loss of ellipsoid zone, OCT en face thickness map constriction, and hyperautofluorescent ring constriction in RP patients. Methods Retrospective case series study. Forty-eight eyes of 24 RP patients with a parafoveal hyperautofluorescent ring were studied. The diagnosis of RP was established by the presence of rod response impairment and a prevalent decrease of scotopic over photopic responses on electroretinography. The FAF and ...
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    3. Real-time assessment of catheter contact and orientation using an integrated optical coherence tomography cardiac ablation catheter

      Real-time assessment of catheter contact and orientation using an integrated optical coherence tomography cardiac ablation catheter
      The efficacy of catheter ablation treatment for atrial fibrillation is directly impacted by the quality of lesion formation. Two parameters that are critical for maximizing energy delivery are sustained catheter contact and orientation. Currently, these parameters must be inferred indirectly through tactile feedback or measurements of bioelectrical impedance and tip force. In this work, we propose a method for discerning contact and orientation based on direct endomyocardial imaging mediated by ...
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    4. High-speed collagen fiber modeling and orientation quantification for optical coherence tomography imaging

      High-speed collagen fiber modeling and orientation quantification for optical coherence tomography imaging
      Quantifying collagen fiber architecture has clinical and scientific relevance across a variety of tissue types and adds functionality to otherwise largely qualitative imaging modalities. Optical coherence tomography (OCT) is uniquely suited for this task due to its ability to capture the collagen microstructure over larger fields of view than traditional microscopy. Existing image processing techniques for quantifying fiber architecture, while accurate and effective, are very slow for processing large datasets ...
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    5. Design and development of optical reflectance spectroscopy and optical coherence tomography catheters for myocardial tissue characterization (Thesis)

      Design and development of optical reflectance spectroscopy and optical coherence tomography catheters for myocardial tissue characterization (Thesis)
      atheter ablation therapy attempts to restore sinus rhythm in arrhythmia patients by producing site-specific tissue modification along regions which cause abnormal electrical activity. This treatment, though widely used, often requires repeat procedures to observe long-term therapeutic benefits. This limitation is driven in part by challenges faced by conventional schemes in validating lesion adequacy at the time of the procedure. Optical techniques are well-suited for the interrogation and characterization of biological ...
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    6. Characterization and modeling of the human left atrium using optical coherence tomography (Thesis)

      Characterization and modeling of the human left atrium using optical coherence tomography (Thesis)
      With current needs to better understand the interaction between atrial tissue microstructure and atrial fibrillation dynamics, micrometer scale imaging with optical coherence tomography has significant potential to provide further insight on arrhythmia mechanisms and improve treatment guidance. However, optical coherence tomography imaging of cardiac tissue in humans is largely unexplored, and the ability of optical coherence tomography to identify the structural substrate of atrial fibrillation has not yet been investigated ...
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    7. Influence of ezetimibe on plaque morphology in patients with ST Elevation Myocardial Infarction assessed by Optical Coherence Tomography: An OCTIVUS sub-study

      Influence of ezetimibe on plaque morphology in patients with ST Elevation Myocardial Infarction assessed by Optical Coherence Tomography: An OCTIVUS sub-study
      Aims The aim of the trial was to examine the influence of ezetimibe on plaque morphology in patients with ST-segment Elevation Myocardial Infarction (STEMI) with respect to fibrous cap thickness (FCT) and arcs of lipid plaque, calcific plaque, and macrophages using Optical Coherence Tomography (OCT). Methods and results In 87 statin nave patients with STEMI treated with primary percutaneous intervention, a non-culprit study plaque in a non-infarct related coronary artery ...
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    8. Artificial Intelligence and Optical Coherence Tomography Imaging

      Artificial Intelligence and Optical Coherence Tomography Imaging
      This review article aimed to highlight the application and use of artificial intelligence (AI) in optical coherence tomography (OCT) imaging in ophthalmology. Artificial intelligence programs seek to simulate intelligent human behavior in computers. With an abundance of patient data, especially with the advent and growing use of imaging modalities such as OCT, AI programs provide us with the unique opportunity to analyze this plethora of information and assist in making ...
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    9. Swept-Source Optical Coherence Tomography Angiography of Retinal Arterial Macroaneurysm With Overlying Hemorrhage

      Swept-Source Optical Coherence Tomography Angiography of Retinal Arterial Macroaneurysm With Overlying Hemorrhage
      A patient in their 90s with hypertension and diabetes type 2 noted the sudden onset of decreased visual acuity of 20/70 OS due to a subinternal limiting membrane macular hemorrhage. Blood obscured the view posteriorly, evidenced by blocked fluorescence exceeding 5 minutes on fluorescein angiography ( Figure , A). Swept-source optical coherence tomography angiography (SS-OCTA) demonstrated a retinal arterial macroaneurysm ( Figure , B). The SS-OCTA uses scatter from high-speed acquisition (100 000 ...
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    10. Heidelberg Engineering Introduces the GMPE Hood Glaucoma Report for SPECTRALIS® OCT

      Heidelberg Engineering Introduces the GMPE Hood Glaucoma Report for SPECTRALIS® OCT
      New feature of the Glaucoma Module Premium Edition offers an intuitive and accurate approach to aid diagnosis and management of glaucoma Heidelberg Engineering, a privately-held imaging and healthcare IT technologies company focused on ophthalmic diagnostic solutions that empower clinicians to improve patient care, announced today that the Hood Glaucoma Report is now available with a software update within the SPECTRALIS OCT Glaucoma Module Premium Edition (GMPE). The GMPE Hood Glaucoma ...
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    11. The “Oculo‐Appositional Reflex”: Should Optical Coherence Tomography–Detected Stent Malapposition Be Corrected?

      The “Oculo‐Appositional Reflex”: Should Optical Coherence Tomography–Detected Stent Malapposition Be Corrected?
      Stent malposition, recognized as an entity with the advent of intravascular imaging, refers to the lack of full contact between stent struts and the vessel wall after percutaneous coronary intervention ( Figure ). Malapposition may be present immediately after placement of stents (acute stent malapposition), or it may develop later (late stent malapposition), which can, in turn, be categorized as late persistent malapposition (ongoing since the time of implantation) or late acquired ...
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    12. An Examination of the Frequency of Paravascular Defects and Epiretinal Membranes in Eyes With Early Glaucoma Using En-face Slab OCT Images

      An Examination of the Frequency of Paravascular Defects and Epiretinal Membranes in Eyes With Early Glaucoma Using En-face Slab OCT Images
      Purpose: To examine the frequency of paravascular defects (PDs) and macular epiretinal membranes (ERMs) in eyes categorized as having mild glaucoma or glaucoma suspect using en-face slab analysis of optical coherence tomography (OCT) scans. Materials and Methods: Fifty-seven glaucomatous eyes, 44 low-risk suspect eyes, and 101 healthy control eyes were included in the study. The 101 glaucomatous and suspect eyes had a mean deviation better than 6dB on the 24-2 ...
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    13. Chip-based frequency combs sources for optical coherence tomography

      Chip-based frequency combs sources for optical coherence tomography
      The Optical coherence tomography (OCT) is a powerful interferometric imaging technique widely used in medical fields such as ophthalmology, cardiology and dermatology, for which footprint and cost are becoming increasingly important. Here we present a platform for miniaturized sources for OCT based on chip-scale lithographically defined microresonators. We show that the proposed platform is compatible with standard commercial spectral domain (SD) OCT systems and enable imaging of human tissue with ...
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    14. Optical coherence tomography circle scans can be used to study many eyes with advanced glaucoma

      Optical coherence tomography circle scans can be used to study many eyes with advanced glaucoma
      Purpose To examine the utility of optical coherence tomography (OCT) for studying eyes with advanced glaucoma [i.e., eyes with a 24-2 visual field (VF) mean deviation (MD) worse than -15 dB], we tested the hypothesis that if these eyes had a 10-2 total deviation (TD) map with points better than -8 dB, then the topographically corresponding regions on the circumpapillary retinal nerve fiber layer (cpRNFL) should show a preserved ...
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    15. Scanning optical coherence tomography probe for in vivo imaging and displacement measurements in the cochlea

      Scanning optical coherence tomography probe for in vivo imaging and displacement measurements in the cochlea
      We developed a spectral domain optical coherence tomography (SDOCT) fiber optic probe for imaging and sub-nanometer displacement measurements inside the mammalian cochlea. The probe, 140 m in diameter, can scan laterally up to 400 m by means of a piezoelectric bender. Two different sampling rates are used, 10 kHz for high-resolution B-scan imaging, and 100 kHz for displacement measurements in order to span the auditory frequency range of gerbil (~50 ...
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  2. About Columbia University

    Columbia University

    Columbia University.  From its beginnings in a schoolhouse in lower Manhattan, Columbia University has grown to encompass two principal campuses: the historic, neoclassical campus in the Morningside Heights neighborhood and the modern Medical Center further uptown, in Washington Heights. Today, Columbia is one of the top academic and research institutions in the world, conducting pathbreaking research in medicine, science, the arts, and the humanities. It includes three undergraduate schools, thirteen graduate and professional schools, and a school of continuing education.