1. Cleveland Clinic

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    1. Mentioned In 172 Articles

    2. Advances In Intraoperative OCT

      Advances In Intraoperative OCT
      Over the past decade, there have been major advances in the field of intraoperative optical coherence tomography. From the development of the portable OCT probe to the first microscope-integrated system, intraoperative OCT has evolved from a research idea to a clinically viable technology. Advances such as heads-up visualization and microscope-integration, as well as the results from large clinical studies, have pushed the field forward. While the feasibility and potential utility ...
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    3. Optical coherence tomography and multiple sclerosis: Update on clinical application and role in clinical trials

      Optical coherence tomography and multiple sclerosis: Update on clinical application and role in clinical trials
      Optical coherence tomography (OCT) has emerged as a fast, non-invasive, inexpensive, high-resolution imaging technique in multiple sclerosis (MS). Retinal layer quantification by OCT facilitates a window into not only local retinal pathology but also global neurodegenerative processes, recognised to be the principal substrates of disability accumulation in MS. While OCT measures in MS have been demonstrated to reflect visual function, inflammatory activity outside of the visual pathways, disability measures including ...
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    4. Cleveland Clinic Receives NIH Grant for Preparation and Planning for the Prospective Randomized Image-Guided Ophthalmic Surgery Clinical Trials

      Cleveland Clinic Receives NIH Grant for Preparation and Planning for the Prospective Randomized Image-Guided Ophthalmic Surgery Clinical Trials
      ...erative OCT in vitreoretinal macular surgery and will be led by Justis P. Ehlers, MD, of the Cleveland Clinic Cole Eye Institute. Dr. Ehlers is a highly trained retina surgeon with extensive experience in the field of in...
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    5. Optical coherence tomography angiography characteristics of choroidal neovascularization requiring varied dosing frequencies in treat-and-extend management: An analysis of the AVATAR study

      Optical coherence tomography angiography characteristics of choroidal neovascularization requiring varied dosing frequencies in treat-and-extend management: An analysis of the AVATAR study
      ...observational study investigating the role of OCTA in various retinal diseases. The study was approved by the Cleveland Clinic Institutional Review Board and adhered to all the tenets of the Declaration of Helsinki. All ...
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    6. IMPACT OF OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY REVIEW STRATEGY ON DETECTION OF CHOROIDAL NEOVASCULARIZATION

      IMPACT OF OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY REVIEW STRATEGY ON DETECTION OF CHOROIDAL NEOVASCULARIZATION
      Purpose: To compare optical coherence tomography angiography ( OCTA ) review strategies for optimizing choroidal neovascularization ( CNV ) detection . Methods: Eyes with CNV in the differential diagnosis were imaged with the Avanti RTVue XR HD (Optovue, Fremont, CA). Three modalities of review for CNV presence were used in each case: a single report generated using automated segmentation within Avanti software; a continuous slab descent video OCTA export; and a manual segmentation approach using ...
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    7. Predictive Model for Macular Hole Closure Speed: Insights From Intraoperative Optical Coherence Tomography

      Predictive Model for Macular Hole Closure Speed: Insights From Intraoperative Optical Coherence Tomography
      Purpose : To establish a predictive model of macular hole (MH) closure speed. Methods : This study was a post hoc analysis of eyes that underwent full-thickness MH repair in the prospective PIONEER intraoperative optical coherence tomography (iOCT) study. The Bioptigen SDOIS system was used for iOCT imaging. All patients underwent standard small-gauge vitrectomy with internal limiting membrane (ILM) peeling, gas tamponade, and postoperative facedown positioning. Before vitrectomy and after ILM peeling ...
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    8. Intraoperative OCT Features and Postoperative Ellipsoid Mapping in Primary Macula-Involving Retinal Detachments from the PIONEER Study

      Intraoperative OCT Features and Postoperative Ellipsoid Mapping in Primary Macula-Involving Retinal Detachments from the PIONEER Study
      Purpose Intraoperative OCT (iOCT) has enabled visualization of subtle structural details during surgical interventions, including retinal detachment repair. The purpose of this study is to evaluate iOCT findings during retinal detachment repair and assess their impact on anatomic and functional outcomes, including outer retinal integrity. Design The PIONEER iOCT study is a prospective cohort IRB-approved study. Subjects Subjects in the PIONEER study undergoing surgical repair for primary macula-involving retinal detachment ...
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    9. Repeatability of Split-Spectrum Amplitude-Decorrelation Angiography to Assess Capillary Perfusion Density Within Optical Coherence Tomography

      Repeatability of Split-Spectrum Amplitude-Decorrelation Angiography to Assess Capillary Perfusion Density Within Optical Coherence Tomography
      BACKGROUND AND OBJECTIVE: To evaluate the repeatability of retinal thickness and vascular density measurements using split-spectrum amplitude-decorrelation angiography (SSADA) with optical coherence tomography (OCT). PATIENTS AND METHODS: Forty patients were divided into seven categories according to their diagnosis: no retinopathy (control), retinal vein occlusion, diabetes with no retinopathy, diabetes with retinopathy, non-exudative age-related macular degeneration (AMD), exudative AMD, and epiretinal membrane. Capillary density and retinal thickness measurements were taken and ...
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    10. Clinic evaluation via outer retinal layer assessment

      Clinic evaluation via outer retinal layer assessment
      Systems and methods are provided for evaluating an eye of a patient from a set of OCT data. A layer segmentation component is configured to identify and segment a plurality of retinal layers within the set of OCT data. The plurality of layers include a layer of interest. A mapping component is configured to generate at least one of an en face representation of the layer of interest and a ...
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    11. Instrument tracking in OCT-assisted surgery

      Instrument tracking in OCT-assisted surgery
      Systems and methods are provided for a microscope-integrated intraoperative scanner system having automated tracking of an instrument tip. A scanning mirror is configured such that a field of view of the OCT system is determined by a position or orientation of the scanning mirror. A drive system is configured to control the scanning mirror. Camera assemblies are configured to determine respective two-dimensional projections of the positions of markers attached to ...
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    12. Optical coherence tomography angiography in eyes with retinal vein occlusion

      Optical coherence tomography angiography in eyes with retinal vein occlusion
      Optical coherence angiography (OCTA) is a noninvasive technique that has been introduced in recent years to detect ophthalmological pathology. The growing usage of OCTA to detect retinal abnormalities can be attributed to its advantages over the reference-standard fluorescein angiography (FA), although both of these techniques can be used in association. OCTA's advantages include its dye independency, its ability to produce depth-resolved images of retinal and choroidal vessels that yield ...
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      Mentions: Cleveland Clinic
    13. Outer Retinal Assessment Using Spectral-Domain Optical Coherence Tomography in Patients With Alzheimer's and Parkinson's Disease

      Outer Retinal Assessment Using Spectral-Domain Optical Coherence Tomography in Patients With Alzheimer's and Parkinson's Disease
      Purpose : To investigate outer retinal parameters among patients with various chronic neurodegenerative disorders by using spectral-domain coherence tomography (OCT) in a prospective cross-sectional cohort study. Methods : A total of 132 participants were enrolled following a comprehensive diagnostic evaluation with neurologic, neuropsychology, and magnetic resonance imaging volumetric evaluations. Participants were 50 years or older, either diagnosed with Alzheimer's disease (AD) dementia, amnestic mild cognitive impairment (MCI), non-AD dementia, Parkinson's ...
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  2. About Cleveland Clinic

    Cleveland Clinic

    Cleveland Clinic is a multispecialty academic medical center located in Cleveland, Ohio, United States. The Cleveland Clinic was established in 1921 by four physicians for the purpose of providing patient care, research, and medical education in an ideal medical setting. One of the largest private medical centers in the world, the Cleveland Clinic saw more than 2,900,000 patient visits in 2005, with 53,000 hospital admissions.  Cleveland Clinic Cole Eye Institute is a state-of-the-art eye care facility with world-class ophthalmologists specializing in eye disease. We diagnose and treat the entire spectrum of conditions of the eye, including eye diseases such as macular degeneration, cataracts, glaucoma, and diabetic retinopathy. Our eye doctors offer such treatments as cataract surgery, photodynamic therapy, and eye surgery for age-related macular degeneration