1. Claude F. Burgoyne

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    1. Mentioned In 28 Articles

    2. Heidelberg Engineering Receives FDA Clearance to Market SPECTRALIS® OCT Glaucoma Module Premium Edition

      Heidelberg Engineering Receives FDA Clearance to Market SPECTRALIS® OCT Glaucoma Module Premium Edition
      ...rations between two groups led by Balwantray C. Chauhan, Ph.D., Dalhousie University in Halifax (Canada), and Claude F. Burgoyne, M.D., Devers Eye Institute in Portland, OR (USA) performed with the SPECTRALIS imaging pla...
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    3. In Vivo Detection of Laminar and Peripapillary Scleral Hypercompliance in Early Monkey Experimental Glaucoma

      In Vivo Detection of Laminar and Peripapillary Scleral Hypercompliance in Early Monkey Experimental Glaucoma
      Purpose : To compare optical coherence tomography (OCT) detected, optic nerve head (ONH) compliance within control and experimental glaucoma (EG) eyes of 15 monkeys at EG onset. Methods : Intraocular pressure (IOP) was chronically elevated in one eye of each animal using a laser. Experimental glaucoma onset was identified using confocal scanning laser tomography (CSLT). Optical coherence tomography ONH imaging (40 radial B-scans) was performed at 10 mm Hg before and after ...
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    4. Comparing Optic Nerve Head Rim Width, Rim Area, and Peripapillary Retinal Nerve Fiber Layer Thickness to Axon Count in Experimental Glaucoma

      Comparing Optic Nerve Head Rim Width, Rim Area, and Peripapillary Retinal Nerve Fiber Layer Thickness to Axon Count in Experimental Glaucoma
      Purpose : We compare spectral-domain optical coherence tomography (SDOCT) measurements of minimum rim width (MRW), minimum rim area (MRA), and peripapillary retinal nerve fiber layer thickness (RNFLT) to complete orbital optic nerve axon counts in nonhuman primates (NHP) with unilateral experimental glaucoma (EG). Methods : Biweekly SDOCT measurements of MRW, MRA, and RNFLT were acquired under manometric IOP control (10 mm Hg) in 51 NHP during baseline (mean SD, 5.0 1 ...
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    5. Total Retinal Blood Flow in a Nonhuman Primate Optic Nerve Transection Model Using Dual-Beam Bidirectional Doppler FD-OCT and Microsphere Method

      Total Retinal Blood Flow in a Nonhuman Primate Optic Nerve Transection Model Using Dual-Beam Bidirectional Doppler FD-OCT and Microsphere Method
      Purpose : We validated noninvasive Doppler-optical coherence tomography (OCT) blood flow measurements against the terminal microsphere method in a surgical induced optic nerve transection nonhuman primate model. Methods : In 6 nonhuman primates, total retinal blood flow (TRBF) was measured with a custom-built dual-beam bidirectional Doppler Fourier Domain (FD)-OCT. Peripapillary retinal nerve fiber layer thickness (RNFLT) was measured by Spectralis spectral-domain (SD)-OCT. Measurements were performed every 10 to 15 days ...
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    6. Emanuel Hospital Receives a 2016 NIH Grant for Optic Nerve Head SD-OCT Imaging in Glaucoma

      Emanuel Hospital Receives a 2016 NIH Grant for Optic Nerve Head SD-OCT Imaging in Glaucoma
      Emanuel Hospital Receives a 2016 NIH Grant for $559,400 for Optic Nerve Head SD-OCT Imaging in Glaucoma. The principal investigator is Claude Burgoyne. The program began in 2010 and ends in 2017. Below is a summary of the proposed work. As a result of discoveries made during the first project period, we propose a paradigm change for clinical assessment of the Optic Nerve Head (ONH), peripapillary retinal nerve fiber ...
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    7. Emanuel Hospital and Health Center Receives NIH Grant for Optical Nerve Head SD-OCT Imaging in Glaucoma

      Emanuel Hospital and Health Center Receives NIH Grant  for Optical Nerve Head SD-OCT Imaging in Glaucoma
      Emanuel Hospital and Health Center Received a 2015 NIH Grant for $553,852 for Optical Nerve Head SD-OCT Imaging in Glaucoma. The principal investigator is Claude Burgoyne. The program begain in 2010 and ends in 2019. Below is a summary of the proposed work. As a result of discoveries made during the first project period, we propose a paradigm change for clinical assessment of the Optic Nerve Head (ONH), peripapillary ...
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    8. Age-related Differences in Longitudinal Structural Change by Spectral Domain Optical Coherence Tomography in Early Experimental Glaucoma

      Age-related Differences in Longitudinal Structural Change by Spectral Domain Optical Coherence Tomography in Early Experimental Glaucoma
      Purpose. To characterize age-related differences in the magnitude of Spectral Domain Optical Coherence Tomography (SDOCT) structural change in early experimental glaucoma (EG). Methods. Both eyes from 4 young (1.4 - 2.6 yrs) and 4 old (18.6 - 21.9 yrs) rhesus monkeys were imaged at least 3 times at baseline, and then every 2 weeks following laser-induced, chronic, unilateral IOP elevation until the onset of EG (Confocal Scanning Laser ...
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    9. The Effect of Age on Optic Nerve Axon Counts, SDOCT Scan Quality, and Peripapillary Retinal Nerve Fiber Layer Thickness Measurements in Rhesus Monkeys

      The Effect of Age on Optic Nerve Axon Counts, SDOCT Scan Quality, and Peripapillary Retinal Nerve Fiber Layer Thickness Measurements in Rhesus Monkeys
      Purpose: To evaluate the effect of age on optic nerve axon counts, spectral-domain optical coherence tomography (SDOCT) scan quality, and peripapillary retinal nerve fiber layer thickness (RNFLT) measurements in healthy monkey eyes. Methods: In total, 83 healthy rhesus monkeys were included in this study (age range: 1.226.7 years). Peripapillary RNFLT was measured by SDOCT. An automated algorithm was used to count 100% of the axons and measure their ...
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    10. Anatomic vs. Acquired Image Frame Discordance in Spectral Domain Optical Coherence Tomography Minimum Rim Measurements

      Anatomic vs. Acquired Image Frame Discordance in Spectral Domain Optical Coherence Tomography Minimum Rim Measurements
      Purpose To quantify the effects of using the fovea to Bruch's membrane opening (FoBMO) axis as the nasal-temporal midline for 30 sectoral (clock-hour) spectral domain optical coherence tomography (SDOCT) optic nerve head (ONH) minimum rim width (MRW) and area (MRA) calculations. Methods The internal limiting membrane and BMO were delineated within 24 radial ONH B-scans in 222 eyes of 222 participants with ocular hypertension and glaucoma. For each eye ...
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    11. Emanuel Hospital Receives NIH Grant for Studying the Optical Nerve Head Using SD-OCT Imaging in Glaucoma

      Emanuel Hospital Receives NIH Grant for Studying the Optical Nerve Head Using SD-OCT Imaging in Glaucoma
      Emanuel Hospital Received a 2013 NIH Grant for $344.250 to study the Optical Nerve Head Using SD-OCT Imaging in Glaucoma. The principal investigator is Claude Burgoyne. The program began in 2010 and ends in 2014. Below is a summary of the proposed work. The primary goal of this project is to test three hypotheses regarding glaucomatous damage to the visual system. First, that clinically detectable neural, glial and connective ...
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    12. Longitudinal Detection of Optic Nerve Head Changes by Spectral Domain Optical Coherence Tomography in Early Experimental Glaucoma

      Longitudinal Detection of Optic Nerve Head Changes by Spectral Domain Optical Coherence Tomography in Early Experimental Glaucoma
      Purpose. To determine if the detection of spectral domain optical coherence tomography (SDOCT) optic nerve head (ONH) change precedes the detection of Confocal Scanning Laser Tomography (CSLT) ONH surface, SDOCT retinal nerve fiber layer (RNFL), Scanning Laser Perimetry (SLP) and multifocal electroretinography (mfERG) change in 8 experimental glaucoma (EG) eyes. Methods. Both eyes from 8 monkeys were tested at least 3 times at baseline, and then every 2 weeks following ...
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    13. Onset and Progression of Peripapillary Retinal Nerve Fiber Layer (RNFL) Retardance Changes Occur Earlier Than RNFL Thickness Changes in Experimental Glaucoma

      Onset and Progression of Peripapillary Retinal Nerve Fiber Layer (RNFL) Retardance Changes Occur Earlier Than RNFL Thickness Changes in Experimental Glaucoma
      ...) Retardance Changes Occur Earlier Than RNFL Thickness Changes in Experimental Glaucoma 1. Brad Fortune, 2. Claude F. Burgoyne, 3. Grant Cull, 4. Juan Reynaud and 5. Lin Wang 1. Discoveries in Sight Research Labo...
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    14. Enhanced Detection of Open-angle Glaucoma with an Anatomically Accurate Optical Coherence Tomography–Derived Neuroretinal Rim Parameter

      Enhanced Detection of Open-angle Glaucoma with an Anatomically Accurate Optical Coherence Tomography–Derived Neuroretinal Rim Parameter
      ...ons + Department of Ophthalmology and Visual Sciences, Dalhousie University, Halifax, Nova Scotia, Canada , * Claude F. Burgoyne, MD Affiliations + Devers Eye Institute, Portland, Oregon Received 27 May 2012; received in...
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    15. Relationship between Orbital Optic Nerve Axon Counts and Retinal Nerve Fiber Layer Thickness Measured by Spectral Domain Optical Coherence Tomograph

      Relationship between Orbital Optic Nerve Axon Counts and Retinal Nerve Fiber Layer Thickness Measured by Spectral Domain Optical Coherence Tomograph
      Purpose: To determine the relationship between total optic nerve axon counts and peripapillary retinal nerve fiber layer thickness (RNFLT) measured in vivo by spectral domain optical coherence tomography (SDOCT). Methods: Twenty-two rhesus macaques had three or more baseline measurements in both eyes of peripapillary RNFLT made by SDOCT (Spectralis, Heidelberg Engineering GmbH). Laser photocoagulation was then applied to the trabecular meshwork of one eye to induce chronic unilateral IOP elevation ...
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  2. About Claude F. Burgoyne

    Claude F. Burgoyne

    Claude F. Burgoyne is a Senior Scientist and Research Director in the Optic Nerve Head Research Laboratory at Devers Eye Institute at the Devers Eye Institute in Portland Oregon.