1. Claude Boccara

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    1. Mentioned In 58 Articles

    2. Feature Of The Week 6/9/13: Imaging of Non-Tumorous and Tumorous Human Brain Tissues with Full-Field OCT

      Feature Of The Week 6/9/13: Imaging of Non-Tumorous and Tumorous Human Brain Tissues with Full-Field OCT
      A prospective study was performed on neurosurgical samples from 18 patients to evaluate the use of full-field optical coherence tomography (FF-OCT) in brain tumor diagnosis. FF-OCT captures en face slices of tissue samples at 1 m resolution in 3D to a penetration depth of around 200 m. A 1 cm2 specimen is scanned at a single depth and processed in about 5 min. This rapid imaging process is non-invasive and ...
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    3. Large Field, High Resolution Full-Field Optical Coherence Tomography: A Pre-clinical Study of Human Breast Tissue and Cancer Assessment

      Large Field, High Resolution Full-Field Optical Coherence Tomography: A Pre-clinical Study of Human Breast Tissue and Cancer Assessment
      We present a benchmark pilot study in which high-resolution Full-Field Optical Coherence Tomography (FF-OCT) was used to image human breast tissue and is evaluated to assess its ability to aid the pathologists management of intra-operative diagnoses. FF-OCT imaging safety was investigated and agreement between FF-OCT and routinely prepared histopathological images was evaluated. The compact setup used for this study provides 1 mm3 resolution and 200 mm imaging depth, and a ...
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    4. Imaging of non tumorous and tumorous human brain tissue with full-field optical coherence tomography

      Imaging of non tumorous and tumorous human brain tissue with full-field optical coherence tomography
      A prospective study was performed on neurosurgical samples from 18 patients to evaluate the use of Full-Field Optical Coherence Tomography (FF-OCT) in brain tumor diagnosis. FF-OCT captures en face slices of tissue samples at 1m resolution in 3D with a typical 200m imaging depth. A 1cm specimen is scanned at a single depth and processed in about 5 minutes. This rapid imaging process is non-invasive and requires neither contrast agent ...
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    5. Optical Tissue Sectioning Using Full Field Optical Coherence Tomography

      Optical Tissue Sectioning Using Full Field Optical Coherence Tomography
      According to a first aspect, the invention relates to a multimodal optical sectioning microscope (200, 400, 600) for full-field imaging of a volumic and scattering sample comprising: - a full-field OCT system for providing an image of a first section in depth of the sample comprising an illumination sub-system (201, 401, 601) and a full-field imaging interferometer with a detection sub system (208, 408, 608) and an optical conjugation device for ...
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    6. Full-Field Optical Coherence Tomography System For Imaging An Object

      Full-Field Optical Coherence Tomography System For Imaging An Object
      The present invention relates to a full-field optical coherence tomography system (300) for imaging an object (319), comprising a light source (301), a first interferometric device having means for splitting an input light beam and comprising at least a reflecting surface (307), a second interferometric device having means for splitting the spectrally modulated output beam and comprising at least a reflecting surface, a multichannel acquisition device (321), the system (300 ...
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    7. Multimodal full-field optical coherence tomography on biological tissue: toward all optical digital pathology

      Multimodal full-field optical coherence tomography on biological tissue: toward all optical digital pathology
      Optical Coherence Tomography (OCT) is an efficient technique for in-depth optical biopsy of biological tissues, relying on interferometric selection of ballistic photons. Full-Field Optical Coherence Tomography (FF-OCT) is an alternative approach to Fourier-domain OCT (spectral or swept-source), allowing parallel acquisition of en-face optical sections. Using medium numerical aperture objective, it is possible to reach an isotropic resolution of about 1x1x1 m. After stitching a grid of acquired images, FF-OCT gives ...
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    8. Feature Of The Week 11/27/11: Langevin Institute and LLTech Investigate In Vivo Cellular Full-Field OCT Imaging with a Rigid Endoscopic Probe

      Feature Of The Week 11/27/11: Langevin Institute and LLTech Investigate In Vivo Cellular Full-Field OCT Imaging with a Rigid Endoscopic Probe
      ...nt Article. Courtesy Anne Latrive from Langevin Institute, ESPCI and LLTech.    References1. Dubois and A.C. Boccara, “Full-field optical coherence tomography” in Optical coherence Tomography, E.D. W. Drexler, J. G. ...
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    9. Single myelin fiber imaging in living rodents without labeling by deep optical coherence microscopy

      Single myelin fiber imaging in living rodents without labeling by deep optical coherence microscopy
      Myelin sheath disruption is responsible for multiple neuropathies in the central and peripheral nervous system. Myelin imaging has thus become an important diagnosis tool. However, in vivo imaging has been limited to either low-resolution techniques unable to resolve individual fibers or to low-penetration imaging of single fibers, which cannot provide quantitative information about large volumes of tissue, as required for diagnostic purposes. Here, we perform myelin imaging without labeling and ...
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    10. Dr Claude Boccara and LLTECH’s Digital Pathology Technology Receive Prestigious NIH Bench-to-Bedside Pioneer Award

      Dr Claude Boccara and LLTECH’s Digital Pathology Technology Receive Prestigious NIH Bench-to-Bedside Pioneer Award
      ...   Panel: http://spie.org/x33387.xml?WT.mc_id=RNIH11PE       About Pr Claude Boccara   Prof. Claude Boccara, is Chief Science Officer at LLTECH, Inc and of Professor at the Institut Langevin at Ecole Sup...
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    11. 31-45 of 58 « 1 2 3 4 »
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  2. About Claude Boccara

    Claude Boccara

    A. Claude Boccara was Dean of Research at ESPCI-ParisTech. Among the optical methods he has developed new microscopies to increase depth and lateral resolution. Recently, ultimate measurements have found new fields of application going from detection of gravitational waves to 3-D imaging though scattering media. He has published more than 300 scientific articles (ISI/ Boccara A* or Boccara C) in international journals. In 2007 he founded the start-up LLTech devoted to medical imaging and diagnostics.

  3. Quotes

    1. The system provides pictures of excellent quality that you can browse easily from the centimeter down to the micrometer scale. I confess having been amazed by the results. This new tool already makes my fellows biologists and physicians enthusiastic: its worth trying it, you will like it.
      In LLTech launches the ultra high resolution - micron level - 3D Light-CT scanner for research
    2. "The CT principle involves using light with a relatively broad spectrum, and the broader the spectrum is, the better the sectioning ability of the technique...That illumination commonly comes from a superluminescent diode or an ultrashort pulsed laser, but Light-CT is completely different.
      In LLTech brings optical biopsies to operating theaters: Coherence tomography technique allows surgeons to see biopsy results in 3D and almost real-time.