1. Christopher Schütze

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    1. Mentioned In 16 Articles

    2. Polarisation-sensitive OCT is useful for evaluating retinal pigment epithelial lesions in patients with neovascular AMD

      Polarisation-sensitive OCT is useful for evaluating retinal pigment epithelial lesions in patients with neovascular AMD
      Background/aims To examine the reproducibility of lesion dimensions of the retinal pigment epithelium (RPE) in neovascular age-related macular degeneration (AMD) with polarisation-sensitive optical coherence tomography (PS-OCT), specifically imaging the RPE. Methods Twenty-six patients (28 eyes) with neovascular AMD were included in this study, and examined by a PS-OCT prototype. Each patient was scanned five times at a 1-day visit. The PS-OCT B-scan located closest to the macular centre presenting ...
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    3. RETINAL PIGMENT EPITHELIUM FINDINGS IN PATIENTS WITH ALBINISM USING WIDE-FIELD POLARIZATION-SENSITIVE OPTICAL COHERENCE TOMOGRAPHY

      RETINAL PIGMENT EPITHELIUM FINDINGS IN PATIENTS WITH ALBINISM USING WIDE-FIELD POLARIZATION-SENSITIVE OPTICAL COHERENCE TOMOGRAPHY
      Purpose: To investigate pigmentation characteristics of the retinal pigment epithelium (RPE) in patients with albinism using wide-field polarization-sensitive optical coherence tomography compared with intensity-based spectral domain optical coherence tomography and fundus autofluorescence imaging. Methods: Five patients (10 eyes) with previously genetically diagnosed albinism and 5 healthy control subjects (10 eyes) were imaged by a wide-field polarization-sensitive optical coherence tomography system (scan angle: 40 x 40[degrees] on the retina), sensitive ...
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    4. Lesion Size Detection in Geographic Atrophy by Polarization-sensitive Optical Coherence Tomography and Correlation to Conventional Imaging Techniques

      Lesion Size Detection in Geographic Atrophy by Polarization-sensitive Optical Coherence Tomography and Correlation to Conventional Imaging Techniques
      Purpose: To investigate the reproducibility of automated lesion size detection in patients with geographic atrophy (GA) using polarization-sensitive spectral domain-OCT (PS-OCT) and to compare findings with scanning laser ophthalmoscopy (SLO), fundus autofluorescence (FAF), and intensity based SD-OCT. Methods: 29 eyes of 22 patients with GA were examined by PS-OCT, selectively identifying the retinal pigment epithelium (RPE). A novel segmentation algorithm was applied, automatically detecting and quantifying areas of RPE atrophy ...
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    5. Large-field high-speed polarization sensitive spectral domain OCT and its applications in ophthalmology

      Large-field high-speed polarization sensitive spectral domain OCT and its applications in ophthalmology
      We present a novel spectral domain polarization sensitive OCT system (PS-OCT) that operates at an A-scan rate of 70 kHz and supports scan angles of up to 40° × 40°. The high-speed imaging allows the acquisition of up to 1024 × 250 A-scans per 3D scan, which, together with the large field of view, considerably increases the informative value of the images. To demonstrate the excellent performance of the new PS-OCT system ...
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    6. Polarization sensitive optical coherence tomography of melanin provides intrinsic contrast based on depolarization

      Polarization sensitive optical coherence tomography of melanin provides intrinsic contrast based on depolarization
      Polarization sensitive optical coherence tomography (PS-OCT) is a functional extension of OCT. In addition to imaging based on tissue reflectivity, PS-OCT also enables depth-resolved mapping of sample polarization properties such as phase-retardation, birefringent axis orientation, Stokes vectors, and degree of polarization uniformity (DOPU). In this study, PS-OCT was used to investigate the polarization properties of melanin. In-vitro measurements in samples with varying melanin concentrations revealed polarization scrambling, i.e. depolarization ...
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    7. Morphologic Characteristics of Idiopathic Juxtafoveal Telangiectasia Using Spectral-Domain and Polarization-Sensitive Optical Coherence Tomography

      Morphologic Characteristics of Idiopathic Juxtafoveal Telangiectasia Using Spectral-Domain and Polarization-Sensitive Optical Coherence Tomography
      Purpose: Idiopathic juxtafoveal telangiectasia (IJT) is characteristically associated with pigmentary changes. Polarization-sensitive spectral-domain optical coherence tomography (PS-SD-OCT) enables imaging of the retinal pigment epithelium (RPE) and similar melanin-containing structures based on specific polarization properties. This study examined IJT with the latest-generation SD-OCT and PS-SD-OCT, identifying pathophysiologically relevant characteristics of the retinal layers and RPE. Methods: Twenty-two eyes of 12 patients with IJT were examined by PS-SD-OCT, with special focus on ...
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    8. Performance of Automated Drusen Detection by Polarization-sensitive Optical Coherence Tomography

      Performance of Automated Drusen Detection by Polarization-sensitive Optical Coherence Tomography
      Purpose: To estimate the potential of polarization-sensitive optical coherence tomography (PS-OCT) for quantitative assessment of drusen in patients with early age-related macular degeneration (AMD). Methods: Fifteen eyes of thirteen patients presenting drusen consistent with AREDS 2 and 3 classification were examined ophthalmoscopically, followed by fundus photography, autofluorescence imaging and three-dimensional scanning using a PS-OCT. For the automated evaluation of drusen location, area and volume, a novel segmentation algorithm was developed ...
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    9. Evaluation of Segmentation Procedures Using Spectral Domain Optical Coherence Tomography in Exudative Age-Related Macular Degeneration

      Evaluation of Segmentation Procedures Using Spectral Domain Optical Coherence Tomography in Exudative Age-Related Macular Degeneration
      Purpose: The purpose of this study was to evaluate standardized automated segmentation procedures of spectral domain optical coherence tomography (SD-OCT) in imaging of age-related macular degeneration. Methods: Twenty-nine eyes of 29 patients with neovascular age-related macular degeneration were included. Three groups were assigned, according to the predominant localization of extravasated fluid in the intra-, subretinal, and subretinal pigment epithelium (RPE) compartment. Automated segmentation procedures were evaluated in B scans of ...
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    10. Segmentation and quantification of retinal lesions in age-related macular degeneration using polarization-sensitive optical coherence tomography

      Segmentation and quantification of retinal lesions in age-related macular degeneration using polarization-sensitive optical coherence tomography
      ...of Vienna, Center for Medical Physics and Biomedical Engineering, Währinger Straße 13, A–1090 Vienna, Austria Christopher Schütze, Ferdinand Schlanitz, Christian Ahlers, and Ursula Schmidt-Erfurth Medical University of V...
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    11. Performance of OCT segmentation procedures to assess morphology and extension in geographic atrophy

      Performance of OCT segmentation procedures to assess morphology and extension in geographic atrophy
      Purpose: Investigating segmentation procedures and morphological findings in time domain (TD) and current spectral domain (SD) optical coherence tomography (OCT) devices in patients with geographic atrophy (GA).Methods: Fifty eyes of 46 patients with GA secondary to AMD and 15 control eyes were examined in this prospective noninterventional comparative case series. All patients underwent Stratus (model 3000), Cirrus (Carl Zeiss Meditec), Spectralis (Spectralis HRA+OCT; Heidelberg Engineering) and 3D-OCT-1000 (Topcon ...
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    12. Imaging of the retinal pigment epithelium in age-related macular degeneration using polarization sensitive optical coherence tomography

      ...tomography Christian Ahlers,^1 Erich Goetzinger,^2 Michael Pircher,^3 Isabelle Golbaz,^4 Franz Prager,^5 Christopher Schütze,^6 Bernhard Baumann,^7 Christoph Hitzenberger,^8 and Ursula Schmidt-Erfurth^9 ^^1Departmen...
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    13. Quantitative measurement of the degree of polarization uniformity of light backscattered by retinal layers by polarization sensitive OCT

      We report on an extension of our previously presented polarization sensitive optical coherence tomography (PS-OCT) technique towards quantitative measurements and imaging of depolarization of light backscattered by the various layers of the human ocular fundus in vivo. We use a state of the art spec ... [Proc. SPIE 7168, 716814 (2009)] published Tue Feb 24, 2009.
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    14. Imaging the human retina in vivo with combined spectral-domain polarization-sensitive optical coherence tomography and scanning laser ophthalmoscopy

      Polarization-sensitive (PS) optical coherence tomography (OCT) allows for depth-resolved measurement of light polarizing properties of different layers in the human retina. Since their inherent polarizing properties are different, the retinal structures can be identified using PS-OCT. We present an ... [Proc. SPIE 7163, 71630N (2009)] published Wed Feb 18, 2009.
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  2. About Christopher Schütze

    Christopher Schütze is with the Center for Biomedical Engineering and Physics and the Department of Ophthalmology at the Medical University of Vienna in Austria.