1. Christian Ahlers

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    1. Mentioned In 29 Articles

    2. Morphologic Characteristics of Idiopathic Juxtafoveal Telangiectasia Using Spectral-Domain and Polarization-Sensitive Optical Coherence Tomography

      Morphologic Characteristics of Idiopathic Juxtafoveal Telangiectasia Using Spectral-Domain and Polarization-Sensitive Optical Coherence Tomography
      Purpose: Idiopathic juxtafoveal telangiectasia (IJT) is characteristically associated with pigmentary changes. Polarization-sensitive spectral-domain optical coherence tomography (PS-SD-OCT) enables imaging of the retinal pigment epithelium (RPE) and similar melanin-containing structures based on specific polarization properties. This study examined IJT with the latest-generation SD-OCT and PS-SD-OCT, identifying pathophysiologically relevant characteristics of the retinal layers and RPE. Methods: Twenty-two eyes of 12 patients with IJT were examined by PS-SD-OCT, with special focus on ...
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    3. Performance of Automated Drusen Detection by Polarization-sensitive Optical Coherence Tomography

      Performance of Automated Drusen Detection by Polarization-sensitive Optical Coherence Tomography
      Purpose: To estimate the potential of polarization-sensitive optical coherence tomography (PS-OCT) for quantitative assessment of drusen in patients with early age-related macular degeneration (AMD). Methods: Fifteen eyes of thirteen patients presenting drusen consistent with AREDS 2 and 3 classification were examined ophthalmoscopically, followed by fundus photography, autofluorescence imaging and three-dimensional scanning using a PS-OCT. For the automated evaluation of drusen location, area and volume, a novel segmentation algorithm was developed ...
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    4. Evaluation of Segmentation Procedures Using Spectral Domain Optical Coherence Tomography in Exudative Age-Related Macular Degeneration

      Evaluation of Segmentation Procedures Using Spectral Domain Optical Coherence Tomography in Exudative Age-Related Macular Degeneration
      Purpose: The purpose of this study was to evaluate standardized automated segmentation procedures of spectral domain optical coherence tomography (SD-OCT) in imaging of age-related macular degeneration. Methods: Twenty-nine eyes of 29 patients with neovascular age-related macular degeneration were included. Three groups were assigned, according to the predominant localization of extravasated fluid in the intra-, subretinal, and subretinal pigment epithelium (RPE) compartment. Automated segmentation procedures were evaluated in B scans of ...
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    5. Comparison of retinal thickness values and segmentation performance of different OCT devices in acute branch retinal vein occlusion

      Comparison of retinal thickness values and segmentation performance of different OCT devices in acute branch retinal vein occlusion
      Purpose To compare retinal thickness (RT) measurement and segmentation performance of time domain (TD, Stratus) and spectral domain (SD) optical coherence tomography (OCT) devices (Cirrus, Spectralis) for imaging macular oedema (ME) secondary to branch retinal vein occlusion (BRVO). Methods In this study, 20 eyes of 20 consecutive patients with acute BRVO were included. A total of 18 unaffected fellow eyes served as control group. RT measurement was analysed in the ...
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    6. Segmentation and quantification of retinal lesions in age-related macular degeneration using polarization-sensitive optical coherence tomography

      Segmentation and quantification of retinal lesions in age-related macular degeneration using polarization-sensitive optical coherence tomography
      ...Biomedical Engineering, Währinger Straße 13, A–1090 Vienna, Austria Christopher Schütze, Ferdinand Schlanitz, Christian Ahlers, and Ursula Schmidt-Erfurth Medical University of Vienna, Department of Ophthalmology, Währin...
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    7. Performance of OCT segmentation procedures to assess morphology and extension in geographic atrophy

      Performance of OCT segmentation procedures to assess morphology and extension in geographic atrophy
      Purpose: Investigating segmentation procedures and morphological findings in time domain (TD) and current spectral domain (SD) optical coherence tomography (OCT) devices in patients with geographic atrophy (GA).Methods: Fifty eyes of 46 patients with GA secondary to AMD and 15 control eyes were examined in this prospective noninterventional comparative case series. All patients underwent Stratus (model 3000), Cirrus (Carl Zeiss Meditec), Spectralis (Spectralis HRA+OCT; Heidelberg Engineering) and 3D-OCT-1000 (Topcon ...
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    8. Evaluation of anterior-segment inflammation and retinal thickness change following cataract surgery

      Purpose: To investigate the physiological retinal response to uneventful cataract surgery using conventional time-domain (TD-OCT) and current spectral-domain optical coherence tomography (SD-OCT) in combination with an assessment of the anterior chamber inflammatory reaction by laser flare/cell meter (LCFM).Methods: Thirty-four patients scheduled for cataract surgery were included in this prospective pilot study. Retinal parameters were examined according to a standardized examination procedure using TD-OCT (Stratus; Carl Zeiss Meditec, Dublin ...
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    9. Imaging of the retinal pigment epithelium in age-related macular degeneration using polarization sensitive optical coherence tomography

      Purpose: Spectral-domain optical coherence tomography (SD-OCT) provided new insights into the understanding of age-related macular degeneration (AMD) but provides limited information on the nature of hyperreflective tissue at the level of the retinal pigment epithelium (RPE). Therefore, a polarization-sensitive SD-OCT (PS-SD-OCT) was used to identify and characterize typical RPE-findings in AMD. Methods: 44 eyes of 44 AMD-patients were included into this prospective case series representing the entire AMD-spectrum from drusen ...
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    10. Automatic and manual segmentation of healthy retinas using high-definition optical coherence tomography

      Purpose: This study compared automatic- and manual segmentation modalities in the retina of healthy eyes using high-definition optical coherence tomography (HD-OCT).Methods: Twenty retinas in 20 healthy individuals were examined using an HD-OCT system (Carl Zeiss Meditec, Inc.). Three-dimensional imaging was performed with an axial resolution of 6 [mu]m at a maximum scanning speed of 25 000 A-scans/second. Volumes of 6 × 6 × 2 mm were scanned. Scans were ...
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    11. Comparison of retinal thickness measurements and segmentation performance of four different spectral and time domain OCT devices in neovascular age-related macular degeneration

      Aims: To evaluate the reliability of different optical coherence tomography (OCT) devices and scanning patterns in the assessment of retinal thickness and segmentation performance in neovascular age-related macular degeneration (nAMD). Methods: 28 eyes with nAMD and 10 healthy eyes were imaged using conventional time domain (TD) OCT as well as three spectral-domain (SD) OCT systems. Radial scans of 6 mm in size were compared between Stratus and Topcon OCT, in ...
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    12. Alterations of intraretinal layers in acute central serous chorioretinopathy

      Purpose: Optical coherence tomography (OCT) is restricted by its low scanning speed and limited resolution. High-definition raster-scanning OCT (HD-OCT) was used to evaluate changes in retinal microstructure in patients with acute central serous chorioretinopathy (CSCR) and to find new morphological features.Methods: Eighteen patients with subretinal fluid accumulation caused by acute CSCR were imaged in a cross-sectional study design. High-speed frequency-domain HD-OCT was used to image an area of 6 ...
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    13. 1-15 of 29 1 2 »
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  2. About Christian Ahlers

    Christian Ahlers is with the Department of Ophthalmology at the Medical University of Vienna.