1. Chinese Academy of Sciences

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    1. Mentioned In 54 Articles

    2. Passively Driven Probe Based on Miniaturized Propeller for Intravascular Optical Coherence Tomography

      Passively Driven Probe Based on Miniaturized Propeller for Intravascular Optical Coherence Tomography
      Optical coherent tomography (OCT) has enabled clinical applications ranging from ophthalmology to cardiology that revolutionized in vivo medical diagnostics in the last few decades, and a variety of endoscopic probes have been developed in order to meet the needs of various endoscopic OCT imaging. We propose a passive driven intravascular optical coherent tomography (IV-OCT) probe in this paper. Instead of using any electrically driven scanning device, the probe makes use ...
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    3. Novel Photoacoustic Microscopy and Optical Coherence Tomography Dual-modality Chorioretinal Imaging in Living Rabbit Eyes

      Novel Photoacoustic Microscopy and Optical Coherence Tomography Dual-modality Chorioretinal Imaging in Living Rabbit Eyes
      Photoacoustic ocular imaging is an emerging ophthalmic imaging technology that can noninvasively visualize ocular tissue by converting light energy into sound waves and is currently under intensive investigation. However, most reported work to date is focused on the imaging of the posterior segment of the eyes of small animals, such as rats and mice, which poses challenges for clinical human translation due to small eyeball sizes. This manuscript describes a ...
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    4. Evaluation of marginal gap of lithium disilicate glass ceramic crowns with optical coherence tomography

      Evaluation of marginal gap of lithium disilicate glass ceramic crowns with optical coherence tomography
      arginal gap (MG) was the most important factor to evaluate the success of crowns. The study was to assess the MG of lithium disilicate glass ceramic crowns with spectral domain optical coherence tomography (OCT) and stereomicroscopy in vitro , and to provide evidence to measure the MG with OCT. Consistency was observed between OCT and stereomicroscopy to measure the MG after cementation. There was no significant difference between the MG of ...
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    5. Automatic Lumen Segmentation in Intravascular Optical Coherence Tomography Images Using Level Set

      Automatic Lumen Segmentation in Intravascular Optical Coherence Tomography Images Using Level Set
      Automatic lumen segmentation from intravascular optical coherence tomography (IVOCT) images is an important and fundamental work for diagnosis and treatment of coronary artery disease. However, it is a very challenging task due to irregular lumen caused by unstable plaque and bifurcation vessel, guide wire shadow, and blood artifacts. To address these problems, this paper presents a novel automatic level set based segmentation algorithm which is very competent for irregular lumen ...
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    6. Automatic spectral calibration for polarization-sensitive optical coherence tomography

      Automatic spectral calibration for polarization-sensitive optical coherence tomography
      Accurate wavelength assignment is important for Fourier domain polarizationsensitive optical coherence tomography. Incorrect wavelength mapping between the orthogonal horizontal (H) and vertical (V) polarization channels leads to broadening the axial point spread function and generating polarization artifacts. To solve the problem, we propose an automatic spectral calibration method by seeking the optimal calibration coefficient between wavenumber kH and kV. The method first performs a rough calibration to get the relationship ...
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    7. Feature Of The Week 09/10/2017: Thermo-elastic Optical Coherence Tomography

      Feature Of The Week 09/10/2017: Thermo-elastic  Optical Coherence Tomography
      The conventional OCT image contrast is derived from elastic scattering, and shows the internal structure of the sample. The determination of the tissue type in OCT images usually depends on the interpretation by the image reader. More accurate tissue type contrast may be achieved by new OCT-based imaging modalities, with sensitivity to other physical parameters than scattering alone. Phase-sensitive OCT can detect tissue motion on nanometer-to- micrometer length scales using ...
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    8. Thermo-elastic optical coherence tomography

      Thermo-elastic optical coherence tomography
      The absorption of nanosecond laser pulses induces rapid thermo-elastic deformation in tissue. A sub-micrometer scale displacement occurs within a few microseconds after the pulse arrival. In this Letter, we investigate the laser-induced thermo-elastic deformation using a 1.5 MHz phase-sensitive optical coherence tomography (OCT) system. A displacement image can be reconstructed, which enables a new modality of phase-sensitive OCT, called thermo-elastic OCT. An analysis of the results shows that the ...
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    9. Microscopic surgery system and navigation method guided by optical coherence tomography (OCT) and automated OCT imaging field calibration

      Microscopic surgery system and navigation method guided by optical coherence tomography (OCT) and automated OCT imaging field calibration
      Provided are a microscopic surgery system and a navigation method guided by optical coherence tomography. The microscopic surgery system may include: an object lens; a surgical microscope unit configured to perform two-dimensional imaging on an area to operate on via the object lens; an optical coherence tomography unit configured to perform two-dimensional tomography imaging on the area via the object lens, with an imaging field calibrated according to that of ...
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    10. Noninvasive chorioretinal imaging in living rabbits using integrated photoacoustic microscopy and optical coherence tomography

      Noninvasive chorioretinal imaging in living rabbits using integrated photoacoustic microscopy and optical coherence tomography
      Most reported photoacoustic ocular imaging work to date uses small animals, such as mice and rats, the eyeball sizes of which are less than one-third of those of humans, posing challenges for clinical translation. Here we developed a novel integrated photoacoustic microscopy (PAM) and optical coherence tomography (OCT) system for dual-modality chorioretinal imaging of larger animals, such as rabbits. The system has quantified lateral resolutions of 4.1 m (PAM ...
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    11. Automatic identification of side branch and main vascular measurements in intravascular optical coherence tomography images

      Automatic identification of side branch and main vascular measurements in intravascular optical coherence tomography images
      Automatic identification of side branch and main vascular measurements in IVOCT images take critical roles in pre-interventional decision making for coronary artery disease treatment. Very little works have been presented on these tasks. In this paper, we proposed a novel side branch identification algorithm which utilizes a newly defined global curvature feature to identify the ostium of side branch. Based on identification results, the main vascular can be segmented automatically ...
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    12. Depth-dependent dispersion compensation for full-depth OCT image

      Depth-dependent dispersion compensation for full-depth OCT image
      A depth-dependent dispersion compensation algorithm for enhancing the image quality of the Fourier-domain optical coherence tomography (OCT) is presented. The dispersion related with depth in the sample is considered. Using the iterative method, an analytical formula for compensating the depth-dependent dispersion in the sample is obtained. We apply depth-dependent dispersion compensation algorithm to process the phantom images andin vivoimages. Using sharpness metric based on variation coefficient to compare the results ...
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    13. Machine learning based detection of age-related macular degeneration (AMD) and diabetic macular edema (DME) from optical coherence tomography (OCT) images

      Machine learning based detection of age-related macular degeneration (AMD) and diabetic macular edema (DME) from optical coherence tomography (OCT) images
      Non-lethal macular diseases greatly impact patients life quality, and will cause vision loss at the late stages. Visual inspection of the optical coherence tomography (OCT) images by the experienced clinicians is the main diagnosis technique. We proposed a computer-aided diagnosis (CAD) model to discriminate age-related macular degeneration (AMD), diabetic macular edema (DME) and healthy macula. The linear configuration pattern (LCP) based features of the OCT images were screened by the ...
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    14. Retroreflective-type Janus microspheres as a novel contrast agent for enhanced optical coherence tomography

      Retroreflective-type Janus microspheres as a novel contrast agent for enhanced optical coherence tomography
      Working principle and SEM image of Janus microsphere (top). Enhanced OCT imaging (bottom) of Janus microspheres in zebrafish stomach (blue dash line) and sinusoids (green arrows) of nude liver. Optical coherence tomography (OCT) is a well-developed technology that utilizes near-infrared light to reconstruct three-dimensional images of biological tissues with micrometer resolution. Improvements of the imaging contrast of the OCT technique are able to further widen its extensive biomedical applications. In ...
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    15. Nondestructive Analysis of Jingdezhen and Longquan Celadon Wares Excavated from Nanhai No.1 Shipwreck

      Nondestructive Analysis of Jingdezhen and Longquan Celadon Wares Excavated from Nanhai No.1 Shipwreck
      The provenance study of ancient ceramics, as an important part in archaeological field, is the researching focus for researchers in scientific and technological archaeology. At present, the provenance study of ancient ceramics mainly depends on chemical analysis technologies while non-destructive physical structural analysis of ceramic glaze is relatively lacking. Therefore, it is difficult to have a comprehensive understanding of ancient ceramics. Optical coherence tomography (OCT) is an emerging non-destructive imaging ...
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    16. Speckle Reduction in 3D Optical Coherence Tomography of Retina by A-Scan Reconstruction

      Speckle Reduction in 3D Optical Coherence Tomography of Retina by A-Scan Reconstruction
      Optical coherence tomography (OCT) is a micrometer-scale, cross-sectional imaging modality for biological tissue. It has been widely used for retinal imaging in ophthalmology. Speckle noise is problematic in OCT. A raw OCT image/volume usually has very poor image quality due to speckle noise, which often obscures the retinal structures. Overlapping scan is often used for speckle reduction in a 2D line-scan. However, it leads to an increase of the ...
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    17. 16-30 of 54 « 1 2 3 4 »
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  2. About Chinese Academy of Sciences

    Chinese Academy of Sciences

    Chinese Academy of Sciences (CAS) is a leading academic institution and comprehensive research and development center in natural science, technological science and high-tech innovation in China. It was founded in Beijing on 1st November 1949 on the basis of the former Academia Sinica (Central Academy of Sciences) and Peiping Academy of Sciences.