1. Chinese Academy of Sciences

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    1. Mentioned In 82 Articles

    2. Tissue self-attention network for the segmentation of optical coherence tomography images on the esophagus

      Tissue self-attention network for the segmentation of optical coherence tomography images on the esophagus
      x Automatic segmentation of layered tissue is the key to esophageal optical coherence tomography (OCT) image processing. With the advent of deep learning techniques, frameworks based on a fully convolutional network are proved to be effective in classifying pixels on images. However, due to speckle noise and unfavorable imaging conditions, the esophageal tissue relevant to the diagnosis is not always easy to identify. An effective approach to address this problem ...
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    3. Boundary Aware U-Net for Retinal Layers Segmentation in Optical Coherence Tomography Images

      Boundary Aware U-Net for Retinal Layers Segmentation in Optical Coherence Tomography Images
      Retinal layers segmentation in optical coherence tomography (OCT) images is a critical step in the diagnosis of numerous ocular diseases. Automatic layers segmentation requires separating each individual layer instance with accurate boundary detection, but remains a challenging task since it suffers from speckle noise, intensity inhomogeneity, and the low contrast around boundary. In this work, we proposed a boundary aware U-Net (BAU-Net) for retinal layers segmentation by detecting accurate boundary ...
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    4. Automatic Characterisation of Human Atherosclerotic Plaque Composition from Intravascular Optical Coherence Tomography Using Artificial Intelligence

      Automatic Characterisation of Human Atherosclerotic Plaque Composition from Intravascular Optical Coherence Tomography Using Artificial Intelligence
      Background Intravascular optical coherence tomography (IVOCT) enables detailed plaque characterisation in-vivo, but visual assessment is time-consuming and subjective. Aims This study aims to develop and validate an automatic framework for IVOCT plaque characterisation using artificial intelligence (AI). Methods IVOCT pullbacks from 5 international centres were analysed in a corelab, annotating basic plaque components, inflammatory markers and other structures. A deep convolutional network with encoding-decoding architecture and pseudo-3D input was developed ...
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    5. Association of plasma trimethylamine N-Oxide level with healed culprit plaques examined by optical coherence tomography in patients with ST-Segment elevation myocardial infarction

      Association of plasma trimethylamine N-Oxide level with healed culprit plaques examined by optical coherence tomography in patients with ST-Segment elevation myocardial infarction
      Background and aims: Healed plaque is a hallmark of previous regional plaque rupture or erosion. We hypothesized that the plasma level of trimethylamine N-oxide (TMAO) is related to healed culprit plaque in ST-segment elevation myocardial infarction (STEMI) patients. Methods and results: A prospective cohort of 206 patients with STEMI, who were examined by optical coherence tomography (OCT) was enrolled in our study. After exclusion, 156 patients were categorized into healed ...
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    6. Feasibility of microscope-integrated swept-source optical coherence tomography in canaloplasty

      Feasibility of microscope-integrated swept-source optical coherence tomography in canaloplasty
      Background: Several researchers have used commercial microscope-integrated optical coherence tomography (OCT) systems in glaucoma surgery, including ab interno trabeculectomy and canaloplasty. However, the 840 nm wavelength light source of the OCT systems is not ideal for imaging the anterior chamber angle structures because of its limited penetration. We evaluated the potential value of a microscope-integrated swept-source OCT system with a 1,310 nm center-wavelength light in canaloplasty for glaucoma. Methods ...
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    7. Trimethylamine N-Oxide Was Not Associated With 30-Day Left Ventricular Systolic Dysfunction in Patients With a First Anterior ST-Segment Elevation Myocardial Infarction After Primary Revascularization: A Sub-analysis From an Optical Coherence Tomography R

      Trimethylamine N-Oxide Was Not Associated With 30-Day Left Ventricular Systolic Dysfunction in Patients With a First Anterior ST-Segment Elevation Myocardial Infarction After Primary Revascularization: A Sub-analysis From an Optical Coherence Tomography R
      Objective: Left ventricular systolic dysfunction (LVSD) after ST-segment elevation myocardial infarction (STEMI) is associated with poor outcome. Trimethylamine N-oxide (TMAO), a gut metabolite, is linked to cardiovascular diseases but its relationship with LVSD after STEMI remains unclear. The present study therefore aimed to investigate the relationship between TMAO and LVSD at 30 days after a first anterior STEMI. Methods: This was a sub-study from the OCTAMI (Optical Coherence Tomography Examination ...
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    8. Correcting intra-volume distortion for AO-OCT using 3D correlation based registration

      Correcting intra-volume distortion for AO-OCT using 3D correlation based registration
      Adaptive optics (AO) based ophthalmic imagers, such as scanning laser ophthalmoscopes (SLO) and optical coherence tomography (OCT), are used to evaluate the structure and function of the retina with high contrast and resolution. Fixational eye movements during a raster-scanned image acquisition lead to intra-frame and intra-volume distortion, resulting in an inaccurate reproduction of the underlying retinal structure. For three-dimensional (3D) AO-OCT, segmentation-based and 3D correlation based registration methods have been ...
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    9. Optimal processing sequence and method combination of linear resampling and spectral shaping in swept-source optical coherence tomography

      Optimal processing sequence and method combination of linear resampling and spectral shaping in swept-source optical coherence tomography
      There are many methods employed for the linear resampling and spectral shaping, the most important and complex signal processing procedures in swept-source optical coherence tomography. In this study, commonly used 4 interpolation methods (IMs) and 4 shaping methods (SMs) were used as an example to study the processing sequences (PSs) and method combinations of the two procedures. The acquired interference spectra at different optical path-length differences, corresponding to the shallow ...
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    10. ROSE: A Retinal OCT-Angiography Vessel Segmentation Dataset and New Model

      ROSE: A Retinal OCT-Angiography Vessel Segmentation Dataset and New Model
      Optical Coherence Tomography Angiography (OCTA) is a non-invasive imaging technique that has been increasingly used to image the retinal vasculature at capillary level resolution. However, automated segmentation of retinal vessels in OCTA has been under-studied due to various challenges such as low capillary visibility and high vessel complexity, despite its significance in understanding many vision-related diseases. In addition, there is no publicly available OCTA dataset with manually graded vessels for ...
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    11. Comparison of two different optical coherence tomography angiography devices in detecting healthy versus glaucomatous eyes - an observational cross-sectional study

      Comparison of two different optical coherence tomography angiography devices in detecting healthy versus glaucomatous eyes - an observational cross-sectional study
      Background: To understand the differences between two different optical coherence tomography angiography (OCTA) devices in detecting glaucomatous from healthy eyes by comparing their vascular parameters, diagnostic accuracy and test-retest reliability. Methods: A cross-sectional observational study was performed on healthy and glaucoma subjects, on whom two sets of OCTA images of optic disc and macula were acquired using both AngioVue (Optovue, USA) and Swept Source (Topcon, Japan) OCTA devices during one ...
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    12. Optical Coherence Tomography Parameters Related to Vision Impairment in Patients with Diabetic Macular Edema: A Quantitative Correlation Analysis

      Optical Coherence Tomography Parameters Related to Vision Impairment in Patients with Diabetic Macular Edema: A Quantitative Correlation Analysis
      Purpose . To quantitatively explore the correlation between optical coherence tomography (OCT) parameters and vision impairment in patients with diabetic macular edema (DME). Methods . This study was a retrospective observational case series. One-hundred eyes from 66 patients with DME were retrospectively included. OCT parameters, including central macular thickness (CMT), height of intraretinal cystoid, subretinal fluid and sponge-like retinal swelling, density of hyperreflective foci (HRF), and integrity of the ellipsoidal zone (EZ ...
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    13. Differential Diagnosis, Clinical Characteristics, and Interventions of Braid-Like Coronary Artery: Case Series Analysis Based on Optical Coherence Tomography

      Differential Diagnosis, Clinical Characteristics, and Interventions of Braid-Like Coronary Artery: Case Series Analysis Based on Optical Coherence Tomography
      Article Sections On this page Research Article | Open Access Volume2020 | Article ID1031675 | https://doi.org/10.1155/2020/1031675 Wen-Xiu Leng, Huan-Huan Wang, Hai Ming Liu, Ying Song, Lian-Jun Xu, Jing-Jing Xu, Xue-Yan Zhao, Xiao-Yan Tan, Rong Li, Zhan Gao, Li-Jian Gao, Jue Chen, Jin-Qing Yuan, Yue-Jin Yang, Ji-Lin Chen," Differential Diagnosis, Clinical Characteristics, and Interventions of Braid-Like Coronary Artery: Case Series Analysis Based on Optical Coherence Tomography ", Journal of ...
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    14. Anterior Segment Inflammation in Pediatric Uveitis Is Associated with Reduced Retinal Vascular Density as Quantified by Optical Coherence Tomography Angiography

      Anterior Segment Inflammation in Pediatric Uveitis Is Associated with Reduced Retinal Vascular Density as Quantified by Optical Coherence Tomography Angiography
      Purpose To analyze the retinal capillary vascular density (VD) as quantified by optical coherence tomography angiography (OCTA) in patients with pediatric uveitis. Methods OCTA images of 32 pediatric uveitis patients and 30 normal controls (NC) were obtained retrospectively. The foveal avascular zone (FAZ) area, VDs in the superficial capillary plexus (SCP) and deep capillary plexus (DCP), the central macular thickness (CMT), and subfoveal choroidal thickness (SFCT) were analyzed and compared ...
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    15. Transient reduction in macular deep capillary density on optical coherence tomography angiography after phacoemulsification surgery in diabetic patients

      Transient reduction in macular deep capillary density on optical coherence tomography angiography after phacoemulsification surgery in diabetic patients
      Background To evaluate macular microvascular changes and associated factors in diabetic patients following uncomplicated phacoemulsification surgery. Methods In this prospective observational study, we enrolled diabetic patients and non-diabetic controls who underwent phacoemulsification surgery. Participants were examined at postoperative day 1 (POD1), 10 (POD10), 30 (POD30), and 90 (POD90), using macular 3x3mm OCT angiography scan (RTVue-XR Avanti; Optovue, Inc., Fremont, CA). Integrated automated algorithms were used to quantify parafoveal vessel density ...
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    16. The effect of software versions on the measurement of retinal vascular densities using optical coherence tomography angiography

      The effect of software versions on the measurement of retinal vascular densities using optical coherence tomography angiography
      Background The goal of the study was to determine the effect of different software versions on the measurement of retinal vessel densities using optical coherence tomography angiography (OCTA) in normal subjects. Methods Thirty-two eyes of eighteen healthy subjects were imaged using two OCTA devices: the Optovue RTVue and the Zeiss Cirrus. The macular 3 3 mm scan protocol was used. The images acquired using the Optovue OCTA device were exported ...
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  2. About Chinese Academy of Sciences

    Chinese Academy of Sciences

    Chinese Academy of Sciences (CAS) is a leading academic institution and comprehensive research and development center in natural science, technological science and high-tech innovation in China. It was founded in Beijing on 1st November 1949 on the basis of the former Academia Sinica (Central Academy of Sciences) and Peiping Academy of Sciences.