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2. Changes in Retinal Vasculature and Thickness after Small Incision Lenticule Extraction with Optical Coherence Tomography Angiography
  
  Explore Hindawi Publishing Corporation May 25 2019 Ophthalmology
  
  Purpose . To evaluate the changes in retinal vessel density and thickness after small incision lenticule extraction (SMILE) with optical coherence tomography angiography (OCTA) in myopic patients. Methods . In this prospective study, SMILE surgeries were done in 46 eyes of 24 patients with spherical equivalent (SE) more than 6.0 diopters ( D ). Retinal vessel density and thickness at the macula and optic nerve were recorded with OCTA before and 1day, 2weeks ...
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  Mentions: Fudan University Chinese Academy of Sciences
3. Optical coherence tomography angiography analysis of the choriocapillary layer in treatment-naïve diabetic eyes
  
  Explore Home - Springer May 23 2019 Ophthalmology
  
  Purpose To evaluate the capillary flow density (CFD) of choriocapillary (CC) microvasculature using optical coherence tomography angiography (OCT-A) in diabetic eyes and the association of CFD and systemic and metabolic factors. Methods Cross-sectional study. This study enrolled 282 eyes of 146 subjects, including 43 healthy control eyes, 56 diabetic eyes without diabetic retinopathy (DR), 43 eyes with mild nonproliferative DR (NPDR), 54 eyes with moderate NPDR, 38 eyes with severe ...
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  Mentions: Chinese Academy of Sciences Peking University
4. Optical coherence tomography angiography for noninvasive evaluation of angiogenesis in a limb ischemia mouse model
  
  Explore Nature Publishing Group Apr 12 2019
  
  We developed an optical coherence tomography angiography technique by improving the speckle contrast algorithm and the imaging process. This technique, which can achieve angiogenesis imaging in vivo without increasing trauma, was used to evaluate the microvasculature in limb ischemia mice. Sixteen left hindlimb ischemia mice were randomly allocated into CuSO 4 and saline groups. Within 7 days after treatment, limb ischemic damage, temperature and histological staining were assessed by traditional ...
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  Mentions: National Institutes of Health FLIR Chinese Academy of Sciences
5. Optical coherence tomography substudy of a prospective multicentre randomised post-market trial to assess the safety and effectiveness of the Firehawk cobalt-chromium coronary stent (rapamycin target-eluting) system for the treatment of atherosclerotic le
  
  Explore eurointervention.org Nov 21 2018 Cardiology
  
  Aims: Durable polymer drug-eluting stents (DP-DES) may contribute to persistent inflammation, delayed endothelial healing and subsequent late DES thrombosis. The aim of this optical coherence tomography (OCT) substudy was to compare healing and neointimal coverage of a novel bioabsorbable polymer sirolimus-eluting stent (Firehawk ) (BP-DES) versus the DP-DES (XIENCE) at 90 days in an all-comers patient population. Methods and results: The TARGET All Comers study is a prospective multicentre randomised post-market ...
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  Mentions: Yale University University College London Patrick W. Serruys
6. Improved speckle contrast optical coherence tomography angiography
  
  Explore ajtr.org Nov 3 2018
  
  Optical coherence tomography (OCT) is becoming a clinically useful and important imaging technique due to its ability to provide high-resolution structural imaging in vivo. Optical coherence tomography angiography (OCTA) can visualize vasculature imaging of biological tissues. With the advent of Fourier-domain OCT, numerous OCTA techniques have been developed to detect the microvasculature in vivo. The macular region of the fundus is separated into retinal and choroid regions by segmentation algorithm ...
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  Mentions: Chinese Academy of Sciences
7. Deep Learning-Based Detection and Segmentation for BVS Struts in IVOCT Images
  
  Explore Home - Springer Oct 24 2018 Cardiology
  
  Bioresorbable Vascular Scaffold (BVS) is the latest stent type for the treatment of coronary artery disease. A major challenge of BVS is that once it is malapposed during implantation, it may potentially increase the risks of late stent thrombosis. Therefore it is important to analyze struts malapposition during implantation. This paper presents an automatic method for BVS malapposition analysis in intravascular optical coherence tomography images. Struts are firstly detected by ...
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  Mentions: Chinese Academy of Sciences
8. A simple system of swept source optical coherence tomography for a large imaging depth range
  
  Explore ScienceDirect Sep 11 2018
  
  In swept source optical coherence tomography (SSOCT), the imaging depth range sometimes limits its application, such as the whole eye measurement. The methods of extending depth range usually need to redesign the system or add some additional devices. In this paper, we propose a simple system of SSOCT for a large imaging depth range. The system is the same as the original SSOCT with using the swept source clock signal ...
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  Mentions: Osami Sasaki Xiangzhao Wang Chinese Academy of Sciences
9. Optical Coherence Tomography Examination in Myocardial Infarction
  
  Explore Home - ClinicalTrials.gov Jul 20 2018 Cardiology , Clinical Trials
  
  Acute myocardial infarction (AMI), which results from coronary artery occlusion due to thrombosis, remains the leading cause of death and disability worldwide. Pathological studies have demonstrated that plaque rupture accompanied by subsequent thrombus formation is the main mechanism responsible for AMI, accounting for approximately two thirds of cases; the remaining approximately one third of cases are the result of plaque erosion. Moreover, previous studies showed that the risk of cardiovascular ...
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  Mentions: Chinese Academy of Sciences
10. Three-dimensional graph-based skin layer segmentation in optical coherence tomography images for roughness estimation
  
  Explore OSA | OSA Publishing Jul 10 2018 Dermatology
  
  Automatic skin layer segmentation in optical coherence tomography (OCT) images is important for a topographic assessment of skin or skin disease detection. However, existing methods cannot deal with the problem of shadowing in OCT images due to the presence of hair, scales, etc. In this work, we propose a method to segment the topmost layer of the skin (or the skin surface) using 3D graphs with a novel cost function ...
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  Mentions: Chinese Academy of Sciences
11. Optical Coherence Tomography Substudy of A Prospective Multicenter Randomized Post-Market Trial to Assess the Safety and Effectiveness of the Firehawk™ Rapamycin Target Eluting Cobalt Chromium Coronary Stent System for the Treatment of Atherosclerotic Les
  
  Explore eurointervention.org Jun 15 2018 Cardiology
  
  Aims: Durable polymer drug-eluting stents (DP DES) may contribute to persistent inflammation, delayed endothelial healing and subsequent late DES thrombosis. The aim of this Optical Coherence Tomography (OCT) sub-study was to compare healing and neointimal coverage of a novel bioabsorbable polymer sirolimus-eluting stent (FIREHAWK) (BP DES) versus the DP DES (XIENCE) at 90 days in an all comers patient population. Methods and results: The TARGET All Comers study is a ...
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  Mentions: University of London Patrick W. Serruys Chinese Academy of Sciences
12. Automatic analysis of bioresorbable vascular scaffolds in intravascular optical coherence tomography images
  
  Explore OSA | OSA Publishing May 5 2018 Cardiology
  
  The bioresorbable vascular scaffold (BVS) is a new generation of bioresorbable scaffold (BRS) for the treatment of coronary artery disease. A potential challenge of BVS is malapposition, which may possibly lead to late stent thrombosis. It is therefore important to conduct malapposition analysis right after stenting. Since an intravascular optical coherence tomography (IVOCT) image sequence contains thousands of BVS struts, manual analysis is labor intensive and time consuming. Computer-based automatic ...
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  Mentions: Chinese Academy of Sciences Shanghai Jiao Tong University
13. Near-infrared and mid-infrared semiconductor broadband light emitters
  
  Explore Nature Publishing Group Apr 27 2018 Broadband Sources
  
  Semiconductor broadband light emitters have emerged as ideal and vital light sources for a range of biomedical sensing/imaging applications, especially for optical coherence tomography systems. Although near-infrared broadband light emitters have found increasingly wide utilization in these imaging applications, the requirement to simultaneously achieve both a high spectral bandwidth and output power is still challenging for such devices. Owing to the relatively weak amplified spontaneous emission, as a consequence ...
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  Mentions: University of Sheffield Chinese Academy of Sciences Richard A. Hogg
14. Passively Driven Probe Based on Miniaturized Propeller for Intravascular Optical Coherence Tomography
  
  Explore Nature Publishing Group Apr 16 2018 Cardiology , Probes
  
  Optical coherent tomography (OCT) has enabled clinical applications ranging from ophthalmology to cardiology that revolutionized in vivo medical diagnostics in the last few decades, and a variety of endoscopic probes have been developed in order to meet the needs of various endoscopic OCT imaging. We propose a passive driven intravascular optical coherent tomography (IV-OCT) probe in this paper. Instead of using any electrically driven scanning device, the probe makes use ...
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  Mentions: Osami Sasaki Xiangzhao Wang Chinese Academy of Sciences
15. Novel Photoacoustic Microscopy and Optical Coherence Tomography Dual-modality Chorioretinal Imaging in Living Rabbit Eyes
  
  Explore jove.com Mar 24 2018
  
  Photoacoustic ocular imaging is an emerging ophthalmic imaging technology that can noninvasively visualize ocular tissue by converting light energy into sound waves and is currently under intensive investigation. However, most reported work to date is focused on the imaging of the posterior segment of the eyes of small animals, such as rats and mice, which poses challenges for clinical human translation due to small eyeball sizes. This manuscript describes a ...
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  Mentions: University of Michigan Chinese Academy of Sciences Peking University
16. Evaluation of marginal gap of lithium disilicate glass ceramic crowns with optical coherence tomography
  
  Explore SPIE Digital Library Mar 4 2018 Dentistry
  
  arginal gap (MG) was the most important factor to evaluate the success of crowns. The study was to assess the MG of lithium disilicate glass ceramic crowns with spectral domain optical coherence tomography (OCT) and stereomicroscopy in vitro , and to provide evidence to measure the MG with OCT. Consistency was observed between OCT and stereomicroscopy to measure the MG after cementation. There was no significant difference between the MG of ...
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  Mentions: Capital Medical University Chinese Academy of Sciences Peking University
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