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1. Mentioned In 61 Articles
2. Application of machine learning method in optical molecular imaging: a review
  
  Explore Home Dec 28 2019
  
  Optical molecular imaging (OMI) is an imaging technology that uses an optical signal, such as near-infrared light, to detect biological tissue in organisms. Because of its specific and sensitive imaging performance, it is applied in both preclinical research and clinical surgery. However, it requires heavy data analysis and a complex mathematical model of tomographic imaging. In recent years, machine learning (ML)-based artificial intelligence has been used in different fields ...
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  Mentions: Chinese Academy of Sciences
3. BIONET: INFUSING BIOMARKER PRIOR INTO GLOBAL-TO-LOCAL NETWORK FOR CHOROID SEGMENTATION IN OPTICAL COHERENCE TOMOGRAPHY IMAGES
  
  Explore arxiv.org Dec 17 2019 Ophthalmology
  
  Choroid is the vascular layer of the eye, which is directly related to the incidence and severity of many ocular diseases. Optical Coherence Tomography (OCT) is capable of imaging both the cross-sectional view of retina and choroid, but the segmentation of the choroid region is challenging because of the fuzzy choroid-sclera interface (CSI). In this paper, we propose a biomarker infused global-to-local network (BioNet) for choroid segmentation, which segments the ...
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  Mentions: Chinese Academy of Sciences
4. Three-dimensional choroidal vascularity index in acute central serous chorioretinopathy using swept-source optical coherence tomography
  
  Explore Home - Springer Nov 19 2019 Ophthalmology
  
  Purpose To evaluate the three-dimensional choroidal vascularity index (CVI) in the eyes with treatment-nave acute central serous chorioretinopathy (CSC) using swept-source optical coherence tomography (SS OCT). Methods In this prospective cross-sectional study, OCT and OCT angiography covered an area of 12 12 mm centered on the fovea. Three-dimensional CVI was defined as the ratio of the choroidal vascular luminal volume to the total choroidal volume. The location of pigment epithelial ...
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  Mentions: Chinese Academy of Sciences
5. Longitudinal neovascular changes on optical coherence tomography angiography in proliferative diabetic retinopathy treated with panretinal photocoagulation alone versus with intravitreal conbercept plus panretinal photocoagulation: a pilot study
  
  Explore Nature Publishing Group Nov 12 2019 Ophthalmology
  
  Purpose To investigate the longitudinal changes in neovascularization of the retinal elsewhere (NVE) size on optical coherence tomography angiography (OCTA) in proliferative diabetic retinopathy (PDR) treated by panretinal photocoagulation (PRP) alone or by single intravitreal conbercept injection plus PRP. Methods A prospective pilot study. Forty-four PDR eyes with NVE confirmed by fundus fluorescein angiography (FFA) and OCTA were included. They were assigned to receive PRP alone (PRP group) or intravitreal ...
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  Mentions: Chinese Academy of Sciences Peking University
6. PERCEPTUAL-ASSISTED ADVERSARIAL ADAPTATION FOR CHOROID SEGMENTATION IN OPTICAL COHERENCE TOMOGRAPHY
  
  Explore arxiv.org Oct 30 2019 Ophthalmology
  
  Accurate choroid segmentation in optical coherence tomography (OCT) image is vital because the choroid thickness is a major quantitative biomarker of many ocular diseases. Deep learning has shown its superiority in the segmentation of the choroid region but subjects to the performance degeneration caused by the domain discrepancies (e.g., noise level and distribution) among datasets obtained from the OCT devices of different manufacturers. In this paper, we present an ...
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  Mentions: Fudan University Chinese Academy of Sciences
7. Automatic fibroatheroma identification in intravascular optical coherence tomography volumes
  
  Explore Home - Springer Oct 24 2019 Cardiology
  
  Coronary heart disease is the most common type of heart disease that leads to heart attacks. The identification of vulnerable plaques, especially the thin-cap fibroatheroma (TCFA), is crucial to the diagnosis of coronary artery disease. Intravascular optical coherence tomography (IVOCT), an emerging imaging modality, has been proven to be useful for the identification of vulnerable plaques. In this work, we propose an approach to identify the volumes with fibroatheroma frames ...
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  Mentions: National University of Singapore Wakayama Medical University Chinese Academy of Sciences
8. Acoustic Radiation Force Optical Coherence Elastography
  
  Explore Home - Springer Oct 14 2019 Cardiology
  
  Mechanical properties, such as the elasticity and viscosity, are often major indicators of diseases. Over the years, tissue mechanical properties have been demonstrated to be an early indicator for cardiovascular disease. Mechanical imaging technologies have been quickly evolving with a goal to effectively diagnose coronary artery disease and atherosclerosis in their early stages. By combining the advantages of acoustic and optical properties, acoustic radiation force optical coherence elastography (ARF-OCE) has ...
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  Mentions: Zhongping Chen UC Irvine Chinese Academy of Sciences
9. Upside-down position leads to choroidal expansion and anterior chamber shallowing: OCT study
  
  Explore BJO Online Sep 13 2019 Ophthalmology
  
  Background To determine whether dynamic changes in choroidal thickness (CT) cause shallowing of the anterior chamber. Methods 34 healthy volunteers were enrolled. The participants in our study adopted the upside-down position for 1.5min, which was the model we used to study the dynamic changes in CT. Intraocular pressure (IOP) elevation, optical coherence tomography images of the choroid and anterior chamber were obtained at baseline, after being in an upside-down ...
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  Mentions: Sun Yat-Sen University Chinese Academy of Sciences Tin Aung
10. Unifying Structure Analysis and Surrogate-driven Function Regression for Glaucoma OCT Image Screening
  
  Explore arxiv.org Aug 3 2019 Ophthalmology
  
  Optical Coherence Tomography (OCT) imaging plays an important role in glaucoma diagnosis in clinical practice. Early detection and timely treatment can prevent glaucoma patients from permanent vision loss. However, only a dearth of automated methods has been developed based on OCT images for glaucoma study. In this paper, we present a novel framework to effectively classify glaucoma OCT images from normal ones. A semi-supervised learning strategy with smoothness assumption is ...
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  Mentions: Chinese Academy of Sciences The Chinese University of Hong Kong
11. Motorized capsule for shadow-free OCT imaging and synchronous beam control
  
  Explore OSA | OSA Publishing Jul 19 2019 Gastroenterology , Probes
  
  We demonstrate a tethered motorized capsule for unobstructed optical coherence tomography (OCT) imaging of the esophagus. By using a distal reflector design, we avoided the common shadow artifact induced by the motor wires. A synchronous driving technique features three types of beam-scanning modes of the capsule, i.e., circumferential beam scanning, localized beam scanning, and accurate beam positioning. We characterized these three modes and carried out ex vivo imaging experiments ...
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  Mentions: Brett E. Bouma Massachusetts General Hospital Harvard University
12. Changes in Retinal Vasculature and Thickness after Small Incision Lenticule Extraction with Optical Coherence Tomography Angiography
  
  Explore Hindawi Publishing Corporation May 25 2019 Ophthalmology
  
  Purpose . To evaluate the changes in retinal vessel density and thickness after small incision lenticule extraction (SMILE) with optical coherence tomography angiography (OCTA) in myopic patients. Methods . In this prospective study, SMILE surgeries were done in 46 eyes of 24 patients with spherical equivalent (SE) more than 6.0 diopters ( D ). Retinal vessel density and thickness at the macula and optic nerve were recorded with OCTA before and 1day, 2weeks ...
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  Mentions: Fudan University Chinese Academy of Sciences
13. Optical coherence tomography angiography analysis of the choriocapillary layer in treatment-naïve diabetic eyes
  
  Explore Home - Springer May 23 2019 Ophthalmology
  
  Purpose To evaluate the capillary flow density (CFD) of choriocapillary (CC) microvasculature using optical coherence tomography angiography (OCT-A) in diabetic eyes and the association of CFD and systemic and metabolic factors. Methods Cross-sectional study. This study enrolled 282 eyes of 146 subjects, including 43 healthy control eyes, 56 diabetic eyes without diabetic retinopathy (DR), 43 eyes with mild nonproliferative DR (NPDR), 54 eyes with moderate NPDR, 38 eyes with severe ...
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  Mentions: Chinese Academy of Sciences Peking University
14. Optical coherence tomography angiography for noninvasive evaluation of angiogenesis in a limb ischemia mouse model
  
  Explore Nature Publishing Group Apr 12 2019
  
  We developed an optical coherence tomography angiography technique by improving the speckle contrast algorithm and the imaging process. This technique, which can achieve angiogenesis imaging in vivo without increasing trauma, was used to evaluate the microvasculature in limb ischemia mice. Sixteen left hindlimb ischemia mice were randomly allocated into CuSO 4 and saline groups. Within 7 days after treatment, limb ischemic damage, temperature and histological staining were assessed by traditional ...
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  Mentions: National Institutes of Health FLIR Chinese Academy of Sciences
15. Optical coherence tomography substudy of a prospective multicentre randomised post-market trial to assess the safety and effectiveness of the Firehawk cobalt-chromium coronary stent (rapamycin target-eluting) system for the treatment of atherosclerotic le
  
  Explore eurointervention.org Nov 21 2018 Cardiology
  
  Aims: Durable polymer drug-eluting stents (DP-DES) may contribute to persistent inflammation, delayed endothelial healing and subsequent late DES thrombosis. The aim of this optical coherence tomography (OCT) substudy was to compare healing and neointimal coverage of a novel bioabsorbable polymer sirolimus-eluting stent (Firehawk ) (BP-DES) versus the DP-DES (XIENCE) at 90 days in an all-comers patient population. Methods and results: The TARGET All Comers study is a prospective multicentre randomised post-market ...
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  Mentions: Yale University University College London Patrick W. Serruys
16. Improved speckle contrast optical coherence tomography angiography
  
  Explore ajtr.org Nov 3 2018
  
  Optical coherence tomography (OCT) is becoming a clinically useful and important imaging technique due to its ability to provide high-resolution structural imaging in vivo. Optical coherence tomography angiography (OCTA) can visualize vasculature imaging of biological tissues. With the advent of Fourier-domain OCT, numerous OCTA techniques have been developed to detect the microvasculature in vivo. The macular region of the fundus is separated into retinal and choroid regions by segmentation algorithm ...
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  Mentions: Chinese Academy of Sciences
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