1. Chien-Chung Tsai

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    1. Mentioned In 14 Articles

    2. Three-dimensional optical coherence tomography apparatus and its application

      Three-dimensional optical coherence tomography apparatus and its application
      Provided herein are devices and systems that apply full-field optical coherence tomography (OCT) technology to three-dimensional skin tissue imaging. A special designed Mirau type objective and an optical microscope module allowing both OCT mode and orthogonal polarization spectral imaging (OPSI) mode are disclosed.
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    3. Feature of The Week 03/26.2017: Segmentation of nucleus and cytoplasm of a single cell in 3D tomogram using OCT

      Feature of The Week 03/26.2017: Segmentation of nucleus and cytoplasm of a single cell in 3D tomogram using OCT
      uclear-to-cytoplasmic (N/C) ratio is an effective feature to distinguish cancer cells from their normal counterparts. In conventional cytopathology, cells printed or smeared on a glass slide were stained and then evaluated by two-dimensional (2D) images through light microscopy. A random rayburst sampling (RRBS) framework was developed to detect the nucleus and cell membrane boundaries in three-dimensional (3D) space. Raw images were acquired through a full-field optical coherence tomography (FF-OCT ...
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    4. Segmentation of nucleus and cytoplasm of a single cell in three-dimensional tomogram using optical coherence tomography

      Segmentation of nucleus and cytoplasm of a single cell in three-dimensional tomogram using optical coherence tomography
      A random rayburst sampling (RRBS) framework was developed to detect the nucleus and cell membrane boundaries in three-dimensional (3-D) space. Raw images were acquired through a full-field optical coherence tomography system with submicron resolutioni.e., 0.8 m 0.8m in lateral and 0.9 m 0.9m in axial directions. The near-isometric resolution enables 3-D segmentation of a nucleus and cell membrane for determining the volumetric nuclear-to-cytoplasmic (N/C ...
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    5. Feature Of The Week 9/28/14: National Taiwan University Reports on Full-depth epidermis tomography using a Mirau-based full-field OCT

      Feature Of The Week 9/28/14: National Taiwan University Reports on Full-depth epidermis tomography using a Mirau-based full-field OCT
      All living things are made of cells. Most living organisms are single cells; others, such as human bodies, are vast multicellular cities with an aggregation of more than 10 billion cells. Non-invasive and high speed imaging of cells and tissues with sub-micron resolution could help unveil functions of living organisms, and facilitate disease/cancer diagnosis, new drug development, etc. Such an imaging modality is one of the key technologies to ...
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    6. Three-dimensional optical coherence tomography confocal imaging apparatus

      Three-dimensional optical coherence tomography confocal imaging apparatus
      A 3D OCT confocal imaging apparatus includes a light source module for providing an illumination beam with wider bandwidth from a crystal fiber; a reference source module; a pickup module; a beam splitter; an optical filter; and a sensor module. When the illumination beam illuminates a sample, a pickup objective lens and a piezoelectric actuator of the pickup module together provide an image beam scanning the sample in depth direction ...
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    7. Optical imaging apparatus and method

      Optical imaging apparatus and method
      The present invention relates to an optical imaging apparatus and a method, and more particularly to an optical imaging apparatus and a method with short coherence length optical source. The apparatus comprises an optical source with a plurality of outputs for providing a reference light and a sample light; a sample probe module for leading the sample light to a sample, and leading an information light out; an interference module ...
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    8. High-Luminance White-Light Point Source Using Ce,Sm : YAG Double-Clad Crystal Fiber

      High-Luminance White-Light Point Source Using Ce,Sm : YAG Double-Clad Crystal Fiber
      Ce and Sm ions codoped yttrium aluminum garnet (Ce,Sm : YAG) double-clad crystal fibers (DCFs) were successfully fabricated using the codrawing laser-heated pedestal growth method. At a pump wavelength of 446 nm, white-light point source was produced from a 10-$mu{hbox {m}}$-core DCF. The amplified spontaneous emissions and the residual pump resulted in a directional high brightness point source. A luminance of $4.5times 10 ^{9}~hbox{cd ...
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    9. Feature Of The Week 4/4/10: Ce3+:YAG double-clad crystal fiber based optical coherence tomography on fish cornea

      Feature Of The Week 4/4/10: Ce3+:YAG double-clad crystal fiber based optical coherence tomography on fish cornea
      Feature Of The Week 4/4/10: With the tremendous success of optical coherence tomography (OCT) in recent years, high resolution and high image fidelity are getting more importance. So far, several approaches have been proposed to achieve high axial resolution, such as multiplexed superluminescent diode, femtosecond laser, continuum generation from photonic crystal fiber, and xenon illuminator. In general, these solutions are either have high cost, exhibit bumpy spectrum, or ...
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    10. High speed interferometric ellipsometer

      A novel high speed interferometric ellipsometer (HSIE) is proposed and demonstrated. It is based on a novel differential-phase decoder which is able to convert the phase modulation into amplitude modulation in a polarized heterodyne interferometer. Not only high detection sensitivity but also fast ... [Opt. Express 16, 7778-7788 (2008)]
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    11. 1-14 of 14
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  2. About Chien-Chung Tsai

    Chien-Chung Tsai

    Chien-Chung Tsai was graduated from Institute of biophotonics of National Yang-Ming University for Master degree and from Graduate Institute of Photonics and Optoelectronics (GIPO) of National Taiwan University (NTU) for Ph. D. degree. Now, he is with postdoctoral work in NTU-GIPO for the prototype development of Mirau-based full-field optical coherence tomography (FF-OCT) via crystal fiber broadband light source. Nowadays, this developed platform was already applied on cornea, liquid crystal, single cells, and in vivo skin tissue. Fields: Heterodyne interferometer and ellipsometer, Liquid crystal display, Broadband crystal fiber light source, Mirau-based full-field OCT system, Multi-functional 3-D microscope