1. Chao Zhou

    0 Comments Leave a Comment

    1-15 of 52 1 2 3 4 »
    1. Mentioned In 52 Articles

    2. Integrated Local Binary Pattern Texture Features for Classification of Breast Tissue Imaged by Optical Coherence Microscopy

      Integrated Local Binary Pattern Texture Features for Classification of Breast Tissue Imaged by Optical Coherence Microscopy
      This paper proposes a texture analysis technique that can effectively classify different types of human breast tissue imaged by Optical Coherence Microscopy (OCM). OCM is an emerging imaging modality for rapid tissue screening and has the potential to provide high resolution microscopic images that approach those of histology. OCM images, acquired without tissue staining, however, pose unique challenges to image analysis and pattern classification. We examined multiple types of texture ...
      Read Full Article
    3. Optical Coherence Tomography for Brain Imaging and Developmental Biology

      Optical Coherence Tomography for Brain Imaging and Developmental Biology
      Optical coherence tomography (OCT) is a promising research tool for brain imaging and developmental biology. Serving as a three-dimensional optical biopsy technique, OCT provides volumetric reconstruction of brain tissues and embryonic structures with micrometer resolution and video rate imaging speed. Functional OCT enables label-free monitoring of hemodynamic and metabolic changes in the brain in vitro and in vivo in animal models. Due to its noninvasiveness nature, OCT enables longitudinal imaging ...
      Read Full Article
    4. Apparatus and method for space-division multiplexing optical coherence tomography

      Apparatus and method for space-division multiplexing optical coherence tomography
      A space-division multiplexing optical coherence tomography apparatus and system is provided. In one embodiment, the system includes a light source, a reference arm, and a sample arm. The sample arm splits the sampling light into a plurality of sampling beams which may be scanned simultaneously onto a surface of a sample. An optical delay may be introduced into the sampling beams before scanning. A plurality of reflected light signals returned ...
      Read Full Article
    5. Label-Free Imaging of Eosinophilic Esophagitis Mouse Models Using Optical Coherence Tomography

      Label-Free Imaging of Eosinophilic Esophagitis Mouse Models Using Optical Coherence Tomography
      Eosinophilic esophagitis (EoE) is an immune-mediated disorder characterized by esophageal inflammation and related structural changes causing symptoms such as feeding difficulties and food impaction. The pathophysiological mechanisms underlying EoE remain poorly understood. Preclinical studies using mouse models have been critical in comprehending human disease mechanisms and associated pathways. In this chapter, we describe an experimental method using a noninvasive label-free optical imaging technique, optical coherence tomography, to characterize the pathophysiological ...
      Read Full Article
    6. Post-doctoral Associate Position in Biophotonics/Biomedical Optical Imaging at Lehigh University

      Post-doctoral Associate Position in Biophotonics/Biomedical Optical Imaging at Lehigh University
      ...ofessors, and a staff of 1,255. For more information, visit http://www.lehigh.edu/ . About Dr. Chao Zhou: Dr. Chao Zhou obtained his Ph.D. degree in physics in 2007 from the University of Pennsylvania, where he worked wi...
      Read Full Article
    7. Post-doctoral Associate Position in Biophotonics / Biomedical Optical Imaging at Lehigh University

      Post-doctoral Associate Position in Biophotonics / Biomedical Optical Imaging at Lehigh University
      ...ofessors, and a staff of 1,255. For more information, visit http://www.lehigh.edu/ . About Dr. Chao Zhou: Dr. Chao Zhou obtained his Ph.D. degree in physics in 2007 from the University of Pennsylvania, where he worked wi...
      Read Full Article
    8. Post-doctoral Associate Position in Biophotonics / Biomedical Optical Imaging at Lehigh University

      Post-doctoral Associate Position in Biophotonics / Biomedical Optical Imaging at Lehigh University
      ...ofessors, and a staff of 1,255. For more information, visit http://www.lehigh.edu/ . About Dr. Chao Zhou: Dr. Chao Zhou obtained his Ph.D. degree in physics in 2007 from the University of Pennsylvania, where he worked wi...
      Read Full Article
    9. Optogenetic pacing in Drosophila melanogaster

      Optogenetic pacing in Drosophila melanogaster
      Electrical stimulation is currently the gold standard for cardiac pacing. However, it is invasive and nonspecific for cardiac tissues. We recently developed a noninvasive cardiac pacing technique using optogenetic tools, which are widely used in neuroscience. Optogenetic pacing of the heart provides high spatial and temporal precisions, is specific for cardiac tissues, avoids artifacts associated with electrical stimulation, and therefore promises to be a powerful tool in basic cardiac research ...
      Read Full Article
    10. A Circadian Clock Gene, Cry, Affects Heart Morphogenesis and Function in Drosophila as Revealed by Optical Coherence Microscopy

      A Circadian Clock Gene, Cry, Affects Heart Morphogenesis and Function in Drosophila as Revealed by Optical Coherence Microscopy
      Circadian rhythms are endogenous, entrainable oscillations of physical, mental and behavioural processes in response to local environmental cues such as daylight, which are present in the living beings, including humans. Circadian rhythms have been related to cardiovascular function and pathology. However, the role that circadian clock genes play in heart development and function in a whole animal in vivo are poorly understood. The Drosophila cryptochrome (dCry) is a circadian clock ...
      Read Full Article
    11. Post-doctoral Associate Position in Biophotonics / Biomedical Optical Imaging at Lehigh University

      Post-doctoral Associate Position in Biophotonics / Biomedical Optical Imaging at Lehigh University
      ...ofessors, and a staff of 1,255. For more information, visit http://www.lehigh.edu/ . About Dr. Chao Zhou: Dr. Chao Zhou obtained his Ph.D. degree in physics in 2007 from the University of Pennsylvania, where he worked wi...
      Read Full Article
    12. Post-doctoral Associate Position in Biophotonics / Biomedical Optical Imaging at Lehigh University

      Post-doctoral Associate Position in Biophotonics / Biomedical Optical Imaging at Lehigh University
      ...ofessors, and a staff of 1,255. For more information, visit http://www.lehigh.edu/ . About Dr. Chao Zhou: Dr. Chao Zhou obtained his Ph.D. degree in physics in 2007 from the University of Pennsylvania, where he worked wi...
      Read Full Article
    13. SPACE-DIVISION Multiplexing Optical Coherence Tomography Apparatus

      SPACE-DIVISION Multiplexing Optical Coherence Tomography Apparatus
      A space-division multiplexing optical coherence tomography apparatus arid system is provided, in one embodiment, the system includes a light source, a reference arm. and a sample arm. The sample arm splits the sampling light into a plurality of sampling beams which may be scanned simultaneously onto a surface of a sample. An optical delay may be introduced into the sampling beams before scanning. A plurality of reflected light signals returned ...
      Read Full Article
    14. System And Method For Parallel Imaging Optical Coherence Tomography

      System And Method For Parallel Imaging Optical Coherence Tomography
      A parallel imaging optical coherence tomography system. In one embodiment, the system includes a light source, a movable scan unit, and an interferometer comprising a reference arm and a sample arm. The scan unit includes a plurality of apertures illuminated by incident light from the light source. The scan unit produces a plurality of light beams transmitted to the interferometer. The light beams are each split producing a plurality of ...
      Read Full Article
    15. Characterization of eosinophilic esophagitis murine models using optical coherence tomography

      Characterization of eosinophilic esophagitis murine models using optical coherence tomography
      Pre-clinical studies using murine models are critical for understanding the pathophysiological mechanisms underlying immune-mediated disorders such as Eosinophilic esophagitis (EoE). In this study, an optical coherence tomography (OCT) system capable of providing three-dimensional images with axial and transverse resolutions of 5 m and 10 m, respectively, was utilized to obtain esophageal images from a murine model of EoE-like disease ex vivo . Structural changes in the esophagus of wild-type ( Tslpr +/+ ) and ...
      Read Full Article
    16. 1-15 of 52 1 2 3 4 »
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. About Chao Zhou

    Chao Zhou

    Chao Zhou obtained his Ph.D. degree in physics in 2007 from the University of Pennsylvania, where he worked with Professor Arjun G. Yodh on the development of diffuse optical spectroscopy and imaging techniques. In August 2007, he joined Professor James G. Fujimoto's Laser Medicine and Medical Imaging Group at the Massachusetts Institute of Technology as a postdoctoral associate. Since then, he has been working on the development of Optical Coherence Tomography (OCT) and Optical Coherence Microscopy (OCM) technologies. In June 2012, he joined the faculty at Lehigh University as an assistant professor in electrical engineering and bioengineering. He has extensive experience in the field of biomedical optical imaging and has contributed to the development and validation of novel modalities for the imaging of humans and animals with various applications ranging from measuring the brain function to monitoring cancer treatments. He has published over 45 peer-reviewed journal articles, and is a member of the International Society for Optical Engineering, American Heart Association and the International Society for Cerebral Blood flow and Metabolism. He is also a peer reviewer for Optics Letters, Optics Express, Biomedical Optics Express, Applied Optics, Journal of Optical Society of America - A, Journal of Biomedical Optics, Medical Physics, Physics in Medicine and Biology, Physiological Measurement, Journal of Selected Topics in Quantum Electronics and several conferences.

  3. Quotes

    1. We’re also using OCT and OCM to look at developmental biology...In current practice, if you want to examine a developing embryo or animal, you have to sacrifice it and cut it up. Our goal is to be able to image embryonic structures in a less destructive way...We can image [interior cross-sections of] the systolic and diastolic rhythms of an embryonic fly's heart, and compare a normal heart to one with cardio-arrhythmia...OCT, when combined with OCM, can get in vivo , 3-D structural and functional images without needing to remove and process tissues.
      In A more accurate and noninvasive look at cancerous tumors