1. Changhuei Yang

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    1. Mentioned In 20 Articles

    2. Acoustic assisted phase conjugate optical tomography

      Acoustic assisted phase conjugate optical tomography

      A light microscope for imaging a sample containing one or more fluorescent agents, comprising a source for generating acoustic waves that are focused at a focus in the sample, wherein the acoustic waves frequency shift a frequency of light passing through the focus, thereby creating a frequency shifted light beam; at least one spatial light modulator (SLM) positioned to illuminate the sample with an output beam that is an optical phase conjugate of the frequency shifted light beam, wherein the output beam is a reflection of a first reference beam off one or more pixels of the SLM, and the ...

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    3. Image reconstruction by position and motion tracking

      Image reconstruction by position and motion tracking

      A system, method, and apparatus provide the ability to reconstruct an image from an object. A hand-held image acquisition device is configured to acquire local image information from a physical object. A tracking system obtains displacement information for the hand-held acquisition device while the device is acquiring the local image information. An image reconstruction system computes the inverse of the displacement information and combines the inverse with the local image information to transform the local image information into a reconstructed local image information. A display device displays the reconstructed local image information.

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    4. Congratulations to Jian Ren from Caltech a Winner of a 2012 Student Travel Grant Award

      Congratulations to Jian Ren from  Caltech a Winner of a 2012 Student Travel Grant Award
      Jian Ren from the California Institute of Technology is one of four winners of the OCT News 2012 student travel grant awards (see prior announcement Here). Below is a summary of his work. Glaucoma is one type of ophthalmic diseases, where ocular hypertension damages optical nerve, making it the second leading cause of blindness worldwide. One major cause of Open Angle Glaucoma is the poor outflow of aqueous humor through the Trabecular Meshwork (TM). Potential treatments include the micro-bypass stents, which are implanted in the TM and shunt fluid directly to the Schlemm’s Canal (SC) to reduce intraocular pressure ...
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    5. Quantitative differential interference contrast (DIC) microscopy and photography based on wavefront sensors

      Quantitative differential interference contrast (DIC) microscopy and photography based on wavefront sensors
      ..., S. Oh, N. Lue, R. R. Dasari and M. S. Feld, Nature Methods 4, 717 (2007). [13] Xiquan Cui, Matthew Lew, and Changhuei Yang; "Quantitative differentialinterference contrast microscopy based on structured-aperture interf...
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    6. Feature Of The Week 5/1/11: Caltech Researchers Develop an OCT Needle Probe for Investigating Open Angle Glaucoma

      Feature Of The Week 5/1/11: Caltech Researchers Develop an OCT Needle Probe for Investigating Open Angle Glaucoma
      Feature Of The Week 5/1/11: One major cause of Open Angle Glaucoma is the poor outflow of aqueous humor through the Trabecular Meshwork (TM). Potential treatments include the micro-bypass stents, which are implanted in the TM and shunt fluid directly to the Schlemm’s Canal (SC) to reduce intraocular pressure. Implanting the stent with the appropriate orientation near a major collector channel (CC) might maximize outflow of aqueous humor.As scleral tissue and the TM are not transparent to visible light, OCT using infrared light may be useful in visualizing and locating collector channels, hence could assist the ...
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    7. Feature Of The Week 2/7/10: Manual-Scanning Optical Coherence Tomography (OCT) Probe Based on Position Tracking

      Feature Of The Week 2/7/10: Manual-Scanning Optical Coherence Tomography (OCT) Probe Based on Position Tracking
      Feature Of The Week 2/7/10: Optical Coherence Tomography (OCT) is now an important modality in the field of biomedical imaging for its high resolution and non-invasive nature. People have been developing OCT endoscopes to penetrate into deep biological tissues and extend the limited light penetration depth in near infrared wavelength region. Different ways of steering the probing beam have been developed over the years. As most of them need some form of mechanical actuation, they usually come with the associated cost of additional hardware that must be integrated onto the probes. An OCT probe that can be manually ...
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    8. Harmonically matched diffraction grating pair

      A method and device realize shallow gratings-based planar beam splitter/combiner. Non-trivial phase shifts between different ports of resulting interferometers are used to acquire full-field phase measurements. The non-trivial phase shifts between different ports of the planar beam splitter/combiner can be adjusted by simply shearing one grating with respect to the second grating. The two shallow diffraction gratings are harmonically-related and can be recorded on a single substrate for compact interferometric based schemes. During the recording process, the two gratings are aligned such that the grating planes and the grating vectors are parallel to that of each other. The ...
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    9. Coherence domain optical imaging techniques (Thesis)

      Coherence domain optical imaging techniques (Thesis)
      Coherence domain optical imaging techniques have been developing quickly in the past few decades after the invention of laser. In this thesis, I will report the imaging methods that constitute my research projects during these years of graduate studies, including paired-angle-rotation scanning (PARS) forward-imaging probe for optical coherence tomography (OCT), full-field phase imaging technique based on harmonically matched diffraction grating (G1G2 grating), and Fresnel zone plate (FZP) based optifluidic microscopy (OFM). Compared with conventional optical microscopy, the coherence domain optical imaging has many advantages and greatly extends the application of imaging techniques. OCT, based on low-coherence interferometry, is a high-resolution ...
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    10. Paired angled rotation scanning probes and methods of use

      Probes, and systems and methods for optically scanning a conical volume in front of a probe, for use with an imaging modality, such as Optical Coherence Tomography (OCT). A probe includes an optical fiber having a proximal end and a distal end and defining an axis, with the proximal end of the optical fiber being proximate a light source, and the distal end having a first angled surface. A refractive lens element is positioned proximate the distal end of the optical fiber. The lens element and the fiber end are both configured to separately rotate about the axis so as ...
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    11. Systems and methods for phase measurements

      Preferred embodiments of the present invention are directed to systems for phase measurement which address the problem of phase noise using combinations of a number of strategies including, but not limited to, common-path interferometry, phase referencing, active stabilization and differential measurement. Embodiment are directed to optical devices for imaging small biological objects with light. These embodiments can be applied to the fields of, for example, cellular physiology and neuroscience. These preferred embodiments are based on principles of phase measurements and imaging technologies. The scientific motivation for using phase measurements and imaging technologies is derived from, for example, cellular biology at ...

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    12. Handheld forward-imaging needle endoscope for ophthalmic optical coherence tomography inspection

      ...ic optical coherence tomography inspection Shuo Han,^1 Marinko V. Sarunic,^3 Jigang Wu,^1 Mark Humayun,^4 and Changhuei Yang^1,2 ^1California Institute of Technology, Department of Electrical Engineering (MC 136-93) ^2De...
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    13. 2-D PSTD Simulation of optical phase conjugation for turbidity suppression

      Turbidity Suppression via Optical Phase Conjugation (TS-OPC) is an optical phenomenon that uses the back propagation nature of optical phase conjugate light field to undo the effect of tissue scattering. We use the computationally efficient and accurate pseudospectral time-domain (PSTD) simulation ... [Opt. Express 15, 16005-16016 (2007)]
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    14. Forward scanning imaging optical fiber probe

      Forward scanning imaging optical fiber probe
      Probes, and systems and methods for optically scanning a conical volume in front of a probe, for use with an imaging modality, such as Optical Coherence Tomography (OCT). A probe includes an optical fiber having a proximal end and a distal end and defining an axis, with the proximal end of the optical fiber being proximate a light source, and the distal end having a first angled surface. A refractive lens element is positioned proximate the distal end of the optical fiber. The lens element and the fiber end are both configured to separately rotate about the axis so as ...
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  2. About Changhuei Yang

    Changhuei Yang

     

    Changhuei Yang is an Associate Professor of Electrical Engineering and Bioengineering at the California Institute of Technology.