1. Changho Lee

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    1. Mentioned In 21 Articles

    2. Numerical-Sampling-Functionalized Real-Time Index Regulation for Direct k-Domain Calibration in Spectral Domain Optical Coherence Tomography

      Numerical-Sampling-Functionalized Real-Time Index Regulation for Direct k-Domain Calibration in Spectral Domain Optical Coherence Tomography
      An index-regulation technique functionalized by numerical sampling for direct calibration of the non-linear wavenumber ( k )-domain to a linear domain in spectral domain optical coherence tomography (SD-OCT) is proposed. The objective of the developed method is to facilitate high-resolution identification of microstructures in biomedical imaging. Subjective optical alignments caused by nonlinear sampling of interferograms in the k -domain tend to hinder depth-dependent signal-to-noise ratios (SNR) and axial resolution in SD-OCT ...
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    3. Ophthalmic laser system integrated with speckle variance optical coherence tomography for real-time temperature monitoring

      Ophthalmic laser system integrated with speckle variance optical coherence tomography for real-time temperature monitoring
      A commercial ophthalmic laser system (R;GEN, Lutronic Corp) was integrated with a swept-source optical coherence tomography (OCT) imaging system for real-time tissue temperature monitoring. M-scan OCT images were acquired during laser-pulse radiation, and speckle variance OCT (svOCT) images were analyzed to deduce temporal signal variations related to tissue temperature change from laser-pulse radiation. A phantom study shows that svOCT magnitude increases abruptly after laser pulse radiation and recovered exponentially ...
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    4. In vivo observation of metamorphosis of Plodia interpunctella Hübner using three-dimensional optical coherence tomography

      In vivo observation of metamorphosis of Plodia interpunctella Hübner using three-dimensional optical coherence tomography
      Morphological assessment and three-dimensional reconstructions of internal structures of Plodia interpunctella Hbner during metamorphosis stages were experimentally demonstrated using optical coherence tomography (OCT) for the first time. The conventional, complex sectioning methods were significantly simplified owing to the non-invasive three-dimensional imaging capability of OCT. Further, this study demonstrates the use of OCT as a non-invasive detection tool for in vivo morphological observation of metamorphosis stages to gain a better understanding ...
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    5. Feasibility study: protein denaturation and coagulation monitoring with speckle variance optical coherence tomography

      Feasibility study: protein denaturation and coagulation monitoring with speckle variance optical coherence tomography
      We performed the feasibility study using speckle variance optical coherence tomography (SvOCT) to monitor the thermally induced protein denaturation and coagulation process as a function of temperature and depth. SvOCT provided the depth-resolved image of protein denaturation and coagulation with microscale resolution. This study was conducted using egg white. During the heating process, as the temperature increased, increases in the speckle variance signal was observed as the egg white proteins ...
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    6. Non-invasive method and apparatus for screening high-quality seeds

      Non-invasive method and apparatus for screening high-quality seeds
      Disclosed is a method and apparatus for the non-invasive selection of high-quality seeds, based on optical coherence tomography, by which pathogen-infected and pathogen-free seeds can be discriminated in a non-invasive manner. The apparatus is operated by the processes of scanning a seed of diagnostic interest in a non-invasive manner using an optical coherence tomographic unit; processing interference signals of the scanned tomographic images to produce tomographic image data of the ...
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    7. In Vivo Near Infrared Virtual Intraoperative Surgical Photoacoustic Optical Coherence Tomography

      In Vivo Near Infrared Virtual Intraoperative Surgical Photoacoustic Optical Coherence Tomography
      Since its first implementation in otolaryngological surgery nearly a century ago, the surgical microscope has improved the accuracy and the safety of microsurgeries. However, the microscope shows only a magnified surface view of the surgical region. To overcome this limitation, either optical coherence tomography (OCT) or photoacoustic microscopy (PAM) has been independently combined with conventional surgical microscope. Herein, we present a near-infrared virtual intraoperative photoacoustic optical coherence tomography (NIR-VISPAOCT) system ...
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    8. Two-axis polydimethylsiloxane-based electromagnetic microelectromechanical system scanning mirror for optical coherence tomography

      Two-axis polydimethylsiloxane-based electromagnetic microelectromechanical system scanning mirror for optical coherence tomography
      Compact size and fast imaging abilities are key requirements for the clinical implementation of an optical coherence tomography (OCT) system. Among the various small-sized technology, a microelectromechanical system (MEMS) scanning mirror is widely used in a miniaturized OCT system. However, the complexities of conventional MEMS fabrication processes and relatively high costs have restricted fast clinical translation and commercialization of the OCT systems. To resolve these problems, we developed a two-axis ...
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    9. A 2-axis Polydimethylsiloxane (PDMS) based electromagnetic MEMS scanning mirror for optical coherence tomography

      A 2-axis Polydimethylsiloxane (PDMS) based electromagnetic MEMS scanning mirror for optical coherence tomography
      Optical coherence tomography (OCT) is a noninvasive imaging tool for visualizing cross-sectional images of biological tissues on a microscale. Various microelectromechanical system (MEMS) techniques have been applied to OCT for endoscopic catheters and handheld probes. Despite having several advantages such as compact sizes and high speeds for real-time imaging, the complexities of the fabrication processes and relatively high costs were bottlenecks for fast clinical translation and commercialization of the earlier ...
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    10. Microscope System, And Method For Providing Augmented Reality Images Of Microscope System

      Microscope System, And Method For Providing Augmented Reality Images Of Microscope System
      Provided is a microscope system. The system comprises: an optical microscope unit for collecting a surface image of an object to be examined; an OCT unit for collecting an optical coherence tomography image of the object to be examined; a PA unit for collecting a photoacoustic image of the object to be examined; an image processing unit for generating an augmented reality image by superimposing the optical coherence tomography image ...
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    11. Method and device for early non-invasive diagnosis of fruit tree disease

      Method and device for early non-invasive diagnosis of fruit tree disease
      The present invention relates to a non-invasive early diagnostic method and device that allows an early diagnosis of Marssonina blotch disease, which infects apple tree leaves, before the occurrence of lesions to enable early prevention of apple Marssonina blotch disease. The method and device of the present invention comprise the following steps: irradiating a broadband light source on an apple tree leaf undergoing diagnosis by means of optical coherence tomography ...
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    12. Non-Invasive Method and Apparatus for Screening High-Quality Seeds

      Non-Invasive Method and Apparatus for Screening High-Quality Seeds
      Disclosed is a method and apparatus for the non-invasive selection of high-quality seeds, based on optical coherence tomography, by which pathogen-infected and pathogen-free seeds can be discriminated in a non-invasive manner. The apparatus is operated by the processes of scanning a seed of diagnostic interest in a non-invasive manner using an optical coherence tomographic unit; processing interference signals of the scanned tomographic images to produce tomographic image data of the ...
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    13. Method And Device For Early Non-Invasive Diagnose Of Fruit Tree Disease

      Method And Device For Early Non-Invasive Diagnose Of Fruit Tree Disease
      The present invention relates to a non-invasive early diagnostic method and device that allows an early diagnosis of Marssonina blotch disease, which infects apple tree leaves, before the occurrence of lesions to enable early prevention of apple Marssonina blotch disease. The method and device of the present invention comprise the following steps: irradiating a broadband light source on an apple tree leaf undergoing diagnosis by means of optical coherence tomography ...
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    14. 1-15 of 21 1 2 »
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  2. About Changho Lee

    Changho Lee is with the School of Electrical Engineering and Computer Science at Kyungpook National University.