1. Chang Gung University

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    1. Mentioned In 90 Articles

    2. Assessment of temporary cerebral effects induced by focused ultrasound with optical coherence tomography angiography

      Assessment of temporary cerebral effects induced by focused ultrasound with optical coherence tomography angiography
      Focused ultrasound (FUS) in combination with microbubbles temporally and locally increases the permeability of the blood-brain barrier (BBB) for facilitating drug delivery. However, the temporary effects of FUS on the brain microstructure and microcirculation need to be addressed. We used label-free optical coherence tomography (OCT) and OCT angiography (OCTA) to investigate the morphological and microcirculation changes in mouse brains due to FUS exposure at different power levels. Additionally, the recovery ...
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    3. Noninvasive structural and microvascular anatomy of oral mucosae using handheld optical coherence tomography

      Noninvasive structural and microvascular anatomy of oral mucosae using handheld optical coherence tomography
      In this study, we demonstrated the feasibility of using a handheld optical coherence tomography (OCT) for in vivo visualizations of the microstructural and microvascular features of various oral mucosal types. To scan arbitrary locations of the oral mucosa, a scanning probe was developed, composed of a probe body fabricated by a 3D printer, miniaturized two-axis galvanometer, relay lenses, and reflective prism. With a 3D printing technique, the probe weight and ...
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    4. Diagnostic capability of peripapillary retinal nerve fiber layer parameters in time-domain versus spectral-domain optical coherence tomography for assessing glaucoma in high myopia

      Diagnostic capability of peripapillary retinal nerve fiber layer parameters in time-domain versus spectral-domain optical coherence tomography for assessing glaucoma in high myopia
      AIM : To evaluate and compare the diagnostic capabilities of peripapillary retinal nerve fiber layer (p-RNFL) parameters of Spectralis optical coherence tomography (OCT) versus Stratus OCT to detect glaucoma in patients with high myopia. METHODS : This is a retrospective, cross-sectional study. Sixty highly myopic eyes of 60 patients were enrolled, with 30 eyes in the glaucoma group and 30 eyes in the control group. All eyes received peripapillary imaging of the ...
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    5. Optical Coherence Tomography Angiography of the Superficial Microvasculature in the Macular and Peripapillary Areas in Glaucomatous and Healthy Eyes

      Optical Coherence Tomography Angiography of the Superficial Microvasculature in the Macular and Peripapillary Areas in Glaucomatous and Healthy Eyes
      Purpose : To quantitatively evaluate the superficial microvasculature in the macular and peripapillary areas in glaucomatous and healthy eyes using optical coherence tomography angiography (OCT-A). Methods : We enrolled 26 eyes of medically managed primary open-angle glaucoma patients and 27 eyes of healthy subjects were enrolled in this prospective study. Measurements of OCT-A vessel density were acquired both in the macular and peripapillary areas. We compared vessel density values, the circumpapillary retinal ...
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    6. Using Optical Coherence Tomography to Identify of Oral Mucosae with 3D-Printing Probe

      Using Optical Coherence Tomography to Identify of Oral Mucosae with 3D-Printing Probe
      Biomedical materials have different optical properties (e.g. absorption) for different wavelengths. Therefore, probing biomedical materials with multiple wavelengths not only can get in-depth understanding of the detected biomedical materials but also can differentiate the detected biomedical materials. To achieve this purpose, in this conference paper, we present our initial results of building up a portable multiple-wavelength biomedical sensing system. At this initial phase, we assembled this kind of system ...
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    7. Contrast-enhanced optical coherence microangiography with acoustic-actuated microbubbles

      Contrast-enhanced optical coherence microangiography with acoustic-actuated microbubbles
      In this study, we propose to use gas-filled microbubbles (MBs) simultaneously actuated by the acoustic wave to enhance the imaging contrast of optical coherence tomography (OCT)-based angiography. In the phantom experiments, MBs can result in stronger backscattered intensity, enabling to enhance the contrast of OCT intensity image. Moreover, simultaneous application of low-intensity acoustic wave enables to temporally induce local vibration of particles and MBs in the vessels, resulting in ...
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    8. Noninvasive imaging of oral mucosae with optical coherence tomography

      Noninvasive imaging of oral mucosae with optical coherence tomography
      In this study, a swept-source optical coherence tomography (OCT) system is developed for in vivo visualization of structural and vascular morphology oral mucosa. For simplification of optical probe fabrication, probe weight, and system setup, the body of the scanning probe is fabricated by a 3D printer to fix the optical components and the mechanical scanning device, and a partially reflective slide is attached at the output end of probe to ...
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    9. Study on laser-assisted drug delivery with optical coherence tomography

      Study on laser-assisted drug delivery with optical coherence tomography
      The nail provides a functional protection to the fingertips and surrounding tissue from external injuries. Nail plate divided into three layers including dorsal, intermediate, and ventral layers. The dorsal layer consists of compact, hard keratins, limiting topical drug delivery through the nail. In this study, we investigate the application of fractional CO 2 laser that produces arrays of microthermal ablation zones (MAZs) to facilitate drug delivery in the nails. Moreover ...
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    10. Imaging outcomes of bioresorbable scaffold overlap: an optical coherence tomography analysis from the ABSORB EXTEND trial

      Imaging outcomes of bioresorbable scaffold overlap: an optical coherence tomography analysis from the ABSORB EXTEND trial
      Aims: The purpose of this study was to assess the vascular response and vessel healing of overlapped Absorb scaffolds (Abbott Vascular, Santa Clara, CA, USA) compared to non-overlapped devices in human coronary arteries as assessed by optical coherence tomography (OCT) in the same treated segment. Methods and results: The ABSORB EXTEND (NCT01023789) trial is a prospective, single-arm, openlabel clinical study which enrolled 800 patients. The planned overlap OCT subgroup in ...
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    11. Retinal Vessel Density in Optical Coherence Tomography Angiography in Optic Atrophy after Nonarteritic Anterior Ischemic Optic Neuropathy

      Retinal Vessel Density in Optical Coherence Tomography Angiography in Optic Atrophy after Nonarteritic Anterior Ischemic Optic Neuropathy
      Aims . To compare optical coherence tomography angiography (OCT-A) retinal vasculature measurements between normal and optic atrophy after nonarteritic anterior ischemic optic neuropathy (NAION) subjects. Design . This prospective observational study was conducted between July 2015 and August 2016 at the ophthalmology outpatient department of a referral center in Taiwan. Peripapillary (4.54.5mm) and parafoveal (66mm) OCT-A scans were acquired. Measurements of the peripapillary region were obtained in two areas: (1 ...
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    12. Peripapillary Vascular Changes in Nonarteritic Anterior Ischemic Optic Neuropathy by Optical Coherence Tomography Angiography: A Case Report | Open Access Journals

      Peripapillary Vascular Changes in Nonarteritic Anterior Ischemic Optic Neuropathy by Optical Coherence Tomography Angiography: A Case Report | Open Access Journals
      Background: To report the sequential peripapillary vascular changes in nonarteritic anterior ischemic optic neuropathy (NAION) with optical coherence tomography angiography (OCTA) Methods: A 60-year-old male presented with right eye painless vision loss leading to inferior field defects and right eye 0.5 vision. The sequential OCTA was performed at presentation and 5 months later to evaluate the peripapillary vascular changes. Results: At presentation, the OCTA revealed decreased peripapillary capillary perfusion ...
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    13. Acoustic-actuated optical coherence angiography

      Acoustic-actuated optical coherence angiography
      Optical coherence tomography (OCT) angiography requires high sensitivity and image penetration for detailed microvascular monitoring. Unfortunately, no effective contrast-medium-enhanced scheme is currently available for imaging improvement. We here propose the simultaneous use of gas-filled microbubbles (MBs) and acoustic actuation to enhance the imaging contrast of OCT angiography. OCT-synchronized acoustic actuation was applied in the presence of MBs, and different moving object tracking angiographic algorithms were tested in in vitro tubing ...
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    14. Evaluation of Laser-Assisted Trans-Nail Drug Delivery with Optical Coherence Tomography

      Evaluation of Laser-Assisted Trans-Nail Drug Delivery with Optical Coherence Tomography
      The nail provides a functional protection to the fingertips and surrounding tissue from external injuries. The nail plate consists of three layers including dorsal, intermediate, and ventral layers. The dorsal layer consists of compact, hard keratins, limiting topical drug delivery through the nail. In this study, we investigate the application of fractional CO 2 laser that produces arrays of microthermal ablation zones (MAZs) to facilitate drug delivery in the nails ...
      Read Full Article
    15. Optical coherence tomography-guided laser microsurgery for blood coagulation with continuous-wave laser diode

      Optical coherence tomography-guided laser microsurgery for blood coagulation with continuous-wave laser diode
      Blood coagulation is the clotting and subsequent dissolution of the clot following repair to the damaged tissue. However, inducing blood coagulation is difficult for some patients with homeostasis dysfunction or during surgery. In this study, we proposed a method to develop an integrated system that combines optical coherence tomography (OCT) and laser microsurgery for blood coagulation. Also, an algorithm for positioning of the treatment location from OCT images was developed ...
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    16. 31-45 of 90 « 1 2 3 4 5 6 »
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  2. About Chang Gung University

    Chang Gung University

    Chang Gung University currently consists of the College of Medicine, College of Engineering, and College of Management. Our University has approximately 490 full-time and 340 part-time faculty members, and has more than 6,100 students enrolled. We have been striving for excellence in both instruction and research area since the establishment of our institution. In taking advantage of Formosa Plastics Group's abundant manufacturing and medical service resources, Chang Gung University aims to be a first-rate internationally renowned university that prepares high standard professional talents in the fields of medical science, high technology, and knowledge management.