1. Center for Ophthalmic Optics and Lasers

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    1. Mentioned In 335 Articles

    2. Measuring Corneal Astigmatism Using Optical Coherence Tomography in Keratoconus

      Measuring Corneal Astigmatism Using Optical Coherence Tomography in Keratoconus
      Purpose: To measure net corneal astigmatism using optical coherence tomography (OCT, Avanti, Optovue) in individuals with keratoconus and compare its repeatability and accuracy with those obtained using Scheimpflug imaging (Pentacam HR, Oculus). Setting: Casey Eye Institute, Portland, Oregon, USA. Design: Prospective cross-sectional observational study. Methods: Net corneal astigmatism was calculated in keratoconic and normal eyes with OCT and Scheimpflug imaging using four settings - pupil or vertex centration settings with a ...
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    3. Postdoctoral Research Fellowship in Anterior Eye OCT Image Processing and Machine Learning at Oregon Health & Science University.

      Postdoctoral Research Fellowship in Anterior Eye OCT Image Processing and Machine Learning at Oregon Health & Science University.
      A postdoctoral research fellow position is immediately available in the Center for Ophthalmic Optics Lasers Lab ( www.coollab.net ), Casey Eye Institute, Oregon Health Science University. The fellowship will focus on interdisciplinary projects in the field of biomedical image processing, visual optics, and machine learning. PhD in Biomedical Engineering, Electrical Engineering, Computer Science, Optics, or related field of research is required. The position is supported by NIH/NEI research grants ...
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    4. Differentiating Between Contact Lens Warpage and Keratoconus Using OCT Maps of Corneal Mean Curvature and Epithelial Thickness

      Differentiating Between Contact Lens Warpage and Keratoconus Using OCT Maps of Corneal Mean Curvature and Epithelial Thickness
      Purpose: To formulate an Epithelial Modulation index to differentiate between eyes with contact lens warpage and keratoconus. Methods: Normal eyes and eyes with either contact lens warpage or keratoconus were scanned by a Fourier-domain optical coherence tomography (OCT) system. Maps of epithelial thickness and anterior surface mean curvature were generated and converted to deviation maps by subtracting the average maps from a healthy population. The Epithelial Modulation index was defined ...
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    5. Peripheral OCT Assisted by Scleral Depression in Retinopathy of Prematurity

      Peripheral OCT Assisted by Scleral Depression in Retinopathy of Prematurity
      Objective: To determine whether handheld widefield optical coherence tomography (OCT) can be used to document retinopathy of prematurity (ROP) stage while using scleral depression to improve peripheral views. Design: Prospective observational study. Participants: Consecutive neonates admitted to the neonatal intensive care unit (NICU) in a single academic medical center who also met criteria for ROP screening and consented for research imaging. Methods: Scleral depression was combined with widefield OCT using ...
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    6. Advantages of Widefield Optical Coherence Tomography in the Diagnosis of Retinopathy of Prematurity

      Advantages of Widefield Optical Coherence Tomography in the Diagnosis of Retinopathy of Prematurity
      Recent advances in portable optical coherence tomography (OCT) and OCT angiography (OCTA) have resulted in wider fields of view (FOV) and shorter capture times, further expanding the potential clinical role of OCT technology in the diagnosis and management of retinopathy of prematurity (ROP). Using a prototype, handheld OCT device, retinal imaging was obtained in non-sedated infants in the neonatal intensive care unit (NICU) as well as sedated infants in the ...
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    7. High speed, long range, deep penetration swept source OCT for structural and angiographic imaging of the anterior eye

      High speed, long range, deep penetration swept source OCT for structural and angiographic imaging of the anterior eye
      This study reports the development of prototype swept-source optical coherence tomography (SS-OCT) technology for imaging the anterior eye. Advances in vertical-cavity surface-emitting laser (VCSEL) light sources, signal processing, optics and mechanical designs, enable a unique combination of high speed, long range, and deep penetration that addresses the challenges of anterior eye imaging. We demonstrate SS-OCT with a 325 kHz A-scan rate, 12.2 m axial resolution (in air), and 15 ...
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    8. Volumetric directional optical coherence tomography

      Volumetric directional optical coherence tomography
      Photoreceptor loss and resultant thinning of the outer nuclear layer (ONL) is an important pathological feature of retinal degenerations and may serve as a useful imaging biomarker for age-related macular degeneration. However, the demarcation between the ONL and the adjacent Henles fiber layer (HFL) is difficult to visualize with standard optical coherence tomography (OCT). A dedicated OCT system that can precisely control and continuously and synchronously update the imaging beam ...
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    9. Prospective evaluation of optical coherence tomography for disease detection in the Casey mobile eye clinic

      Prospective evaluation of optical coherence tomography for disease detection in the Casey mobile eye clinic
      This study was designed to evaluate iVue Spectral-domain optical coherence tomography (SD-OCT) effectiveness in screening for eye disease compared to clinical examination. Subjects were recruited from the Casey Eye Community Outreach Program Mobile Clinic during its routinely scheduled outreach clinics to indigent, underserved populations throughout Oregon. Macular optical coherence tomography interpretation and automated optical coherence tomography analysis were compared to the clinical examination, with specific attention to findings indicative of ...
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    10. Oregon Health and Science University Receives NIH Grant for OCT Angiography for Neovascular Age-related Macular Degeneration

      Oregon Health and Science University Receives NIH Grant for OCT Angiography for Neovascular Age-related Macular Degeneration
      Oregon Health and Science University Receives a 2021 NIH Grant for $471,602 for OCT Angiography for Neovascular Age-related Macular Degeneration. The principal investigator is Yali Jia. Below is a summary of the proposed work. Neovascular age-related macular degeneration (AMD), characterized by the presence of choroidal neovascularization (CNV), accounts for the majority of AMD related vision loss. Invasive dye-based fluorescein angiography (FA) remains the gold standard for CNV detection. Using ...
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    11. Optical coherence tomographic angiography study of perfusion recovery after surgical lowering of intraocular pressure

      Optical coherence tomographic angiography study of perfusion recovery after surgical lowering of intraocular pressure
      We investigated the time and location of retinal perfusion recovery after surgical intraocular pressure (IOP) lowering in glaucoma by using optical coherent tomography angiography (OCTA). Seventeen patients were analyzed. The 4.54.5-mm OCTA scans centered on the disc were performed preoperatively and postoperatively at 6 weeks, 3 months, and 6 months. The peripapillary retinal nerve fiber layer (NFL) thickness, NFL plexus capillary density (NFLP-CD) and visual field (VF) were ...
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    12. Normative intercapillary distance and vessel density data in the temporal retina assessed by wide-field spectral-domain optical coherence tomography angiography

      Normative intercapillary distance and vessel density data in the temporal retina assessed by wide-field spectral-domain optical coherence tomography angiography
      A limitation of conventional optical coherence tomography angiography (OCTA) is the limited field of view normally used in data acquisition. As the technology improves, larger fields of view that capture information away from the macular are being explored in order to provide an enhanced ability to detect pathology. However, normative measurements for important OCTA metrics like vessel density and intercapillary distance are not currently well-characterized in the peripheral retina. In ...
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    13. Accuracy of OCT-derived net corneal astigmatism measurement

      Accuracy of OCT-derived net corneal astigmatism measurement
      Purpose: To assess the repeatability and accuracy of corneal astigmatism measurement with a spectral-domain optical coherence tomography (OCT) system (Avanti, Optovue) and compare them with Scheimpflug imaging (Pentacam HR, Oculus) and swept-source optical biometry (IOLMaster 700, Carl Zeiss Mediatec AG). Setting: Casey Eye Institute, Oregon Health Science University, Portland, Oregon, USA. Design: Prospective cross-sectional observational study. Methods: Sixty pseudophakic eyes with monofocal non-toric intraocular lens that previously had refractive surgery ...
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    14. Effect of algorithms and covariates in glaucoma diagnosis with optical coherence tomography angiography

      Effect of algorithms and covariates in glaucoma diagnosis with optical coherence tomography angiography
      Purpose: To assess the effects of algorithms and covariates in glaucoma diagnosis with optical coherence tomography angiography (OCTA). Methods: In this prospective cross-sectional study, one eye each of 36 normal controls and 64 patients with glaucoma underwent 4.5 mm disc-centred and 6 mm macula-centred OCTA scans. The peripapillary nerve fibre layer plexus capillary density (NFLP-CD) and macular superficial vascular complex vessel density (SVC-VD) were measured using both a commercial ...
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    15. Oregon Health and Science University Receives NIH Grant for Optical Coherence Tomography-Aided Differential Diagnosis and Treatment of Irregular Corneas

      Oregon Health and Science University Receives NIH Grant for Optical Coherence Tomography-Aided Differential Diagnosis and Treatment of Irregular Corneas
      Oregon Health and Science University Receives a 2021 NIH Grant for $373,450 for Optical Coherence Tomography-Aided Differential Diagnosis and Treatment of Irregular Corneas. The principal investigator is Yan Li. Below is a summary of the proposed work. To see well, the cornea must maintain near perfect clarity and shape. Several disease processes can distort corneal shape and degrade vision. These include ectasia/keratoconus (stromal thinning and bulging), primary epithelial ...
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    16. 1-15 of 335 1 2 3 4 ... 21 22 23 »
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  2. About Center for Ophthalmic Optics and Lasers

    Center for Ophthalmic Optics and Lasers

    The Center for Ophthalmic Optics and Lasers (COOL) at Doheny Eye Institute, University of Southern California (USC) is a state of the art research center focusing on the application of biomedical optics in clinical medicine. COOL lab emcompass an extensive range of research areas in both optics and ophthalmology. The mission of the center is to: "Conserve, improve and restore vision through advances in laser and optical technology".