1. Center for Ophthalmic Optics and Lasers

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    1. Mentioned In 314 Articles

    2. Oregon Science and Health University Receives NIH Grant for Applications of Ultrahigh-Speed Long-Range Wide-Field OCT in Anterior Eye Diseases

      Oregon Science and Health University Receives NIH Grant  for Applications of Ultrahigh-Speed Long-Range Wide-Field OCT in Anterior Eye Diseases
      Oregon Science and Health University Receives a 2021 NIH Grant for $440,684 for Applications of Ultrahigh-Speed Long-Range Wide-Field OCT in Anterior Eye Diseases. The principal investigator is David Huang. Below is a summary of the proposed work. Optical coherence tomography (OCT) is uniquely able to achieve micron depth resolution while imaging a large 3-dimensional (3D) volume. This enables 3D imaging and precise measurements in the anterior segment of the ...
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    3. Plexus-specific retinal vascular anatomy and pathologies as seen by projection-resolved optical coherence tomographic angiography

      Plexus-specific retinal vascular anatomy and pathologies as seen by projection-resolved optical coherence tomographic angiography
      Optical coherence tomographic angiography (OCTA) is a novel technology capable of imaging retinal vasculature three-dimensionally at capillary scale without the need to inject any extrinsic dye contrast. However, projection artifacts cause superficial retinal vascular patterns to be duplicated in deeper layers, thus interfering with the clean visualization of some retinal plexuses and vascular pathologies. Projection-resolved OCTA (PR-OCTA) uses post-processing algorithms to reduce projection artifacts. With PR-OCTA, it is now possible ...
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    4. Plexus-specific retinal capillary avascular area in exudative age-related macular degeneration with projection-resolved OCT angiography

      Plexus-specific retinal capillary avascular area in exudative age-related macular degeneration with projection-resolved OCT angiography
      Objective To detect the plexus-specific retinal capillary avascular area in exudative age-related macular degeneration (EAMD) with projection-resolved optical coherence tomography angiography (PR-OCTA). Methods and analysis In this prospective cross-sectional single centre study, eyes with treatment-nave EAMD underwent macular 33mm OCTA with AngioVue system. OCTA scans were analysed and processed including three-dimensional projection artefact removal, retinal layer semi-automated segmentation and en face angiogram generation. Automated quantification of extrafoveal (excluding the central ...
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    5. Optical Instrumentation Position Opening at Oregon Health & Science University

      Optical Instrumentation Position Opening at Oregon Health & Science University
      ... is to conserve, improve and restore vision through advances in laser and optical technology. Description The Center for Ophthalmic Optics and Lasers (COOL) at the Casey Eye Institute, Oregon Health Science University i...
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    6. OHSU physician honored for co-invention of eye-imaging technology

      OHSU physician honored for co-invention of eye-imaging technology
      An ophthalmologist and researcher at Oregon Health Science University Casey Eye Institute is being honored for co-inventing an eye imaging technology that is widely used to diagnose and guide treatment for people with the leading causes of blindness. David Huang, M.D., Ph.D. , will be awarded a Visionary Prize from the Sanford and Susan Greenberg Prize to End Blindness during a live-streamed ceremony on Dec. 14. Huang is among ...
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    7. Historic Effort to 'End Blindness" Marks a Major Milestone with Leading Scientist Recognized for Pioneering Work at VIP Ceremony Featuring Tribute To Ruth Bader Ginsburg

      Historic Effort to 'End Blindness" Marks a Major Milestone with Leading Scientist Recognized for Pioneering Work at VIP Ceremony Featuring Tribute To Ruth Bader Ginsburg
      The December 14, 2020, streamed ceremony to feature Art Garfunkel, Margaret Atwood, Al Gore, Michael Bloomberg, Sen. Chris Coons, Frank Stella, and a special appearance by Grammy Awardwinning jazz great Diane Schuur Ceremony to also feature moving tribute to late Ruth Bader Ginsburg, including footage of Justice Ginsburg reading from End Blindness co-founder Sanford D. Greenbergs memoir, Hello Darkness, My Old Friend End Blindness 2020an unprecedented joint effort by leading ...
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    8. Keratoconus Detection using OCT Corneal and Epithelial Thickness Map Parameters and Patterns

      Keratoconus Detection using OCT Corneal and Epithelial Thickness Map Parameters and Patterns
      Purpose: To detect keratoconus using optical coherence tomography (OCT) corneal map parameters and patterns. Setting: Casey Eye Institute, Oregon Health Science University, Portland, Oregon, USA DESIGN:: Cross-sectional observational study. Methods: A spectral-domain OCT was used to acquire corneal and epithelial thickness maps in normal, manifest keratoconic, subclinical keratoconic, and forme fruste keratoconic (FFK) eyes. A two-step decision tree was designed. An eye will be classified as keratoconus if both decision ...
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    9. A Coincident Thinning Index for Keratoconus Identification Using OCT Pachymetry and Epithelial Thickness Maps

      A Coincident Thinning Index for Keratoconus Identification Using OCT Pachymetry and Epithelial Thickness Maps
      PURPOSE: To develop a coincident thinning (CTN) index to differentiate between keratoconic and healthy corneas using optical coherence tomography (OCT) measurements of pachymetry and epithelial thickness. METHODS: Pattern deviation maps of pachymetry and epithelial thickness were generated using Fourier-domain OCT images of the cornea. The co-localized thinning of the two maps was quantified using a novel CTN index, which was calculated from Gaussian fits of the regions of maximum relative ...
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    10. Scleral Lens Fitting Using Wide-Field OCT

      Scleral Lens Fitting Using Wide-Field OCT
      The purpose of this study is to see if OCT technology can optimize scleral contact lens fittings. Subjects with keratoconus, post-penetrating keratoplasty (PK), post-LASIK ectasia, post-radial keratotomy (RK), or a variety of anterior surface disorders requiring scleral lens fittings will be considered for enrollment. For each study eye, a clinically-selected scleral lens fit will be compared against an OCT-selected lens fit. The quality of each lens fit will be determined ...
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    11. Split-spectrum amplitude-decorrelation angiography with optical coherence tomography

      Split-spectrum amplitude-decorrelation angiography with optical coherence tomography
      Amplitude decorrelation measurement is sensitive to transverse flow and immune to phase noise in comparison to Doppler and other phase-based approaches. However, the high axial resolution of OCT makes it very sensitive to the pulsatile bulk motion noise in the axial direction. To overcome this limitation, we developed split-spectrum amplitude-decorrelation angiography (SSADA) to improve the signal-to-noise ratio (SNR) of flow detection. The full OCT spectrum was split into several narrower ...
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    12. Oregon Health & Science University Receives a NIH Grant for Wide-Field and Projection-Resolved Optical Coherence Tomography Angiography in Diabetic Retinopathy

      Oregon Health & Science University Receives a NIH Grant  for Wide-Field and Projection-Resolved Optical Coherence Tomography Angiography in Diabetic Retinopathy
      Oregon Health Science University Receives a 2020 NIH Grant for $424,803 for Wide-Field and Projection-Resolved Optical Coherence Tomography Angiography in Diabetic Retinopathy. The principal investigator is Yali Jia. Below is a summary of the proposed work. Our group has demonstrated that optical coherence tomography angiography (OCTA) can address many of the disadvantages of fluorescein angiography (FA) in diabetic retinopathy (DR). OCTA uses the intrinsic contrast of blood cell motion ...
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    13. Sensorless adaptive-optics optical coherence tomographic angiography

      Sensorless adaptive-optics optical coherence tomographic angiography
      Optical coherence tomographic angiography (OCTA) can image the retinal blood flow but visualization of the capillary caliber is limited by the low lateral resolution. Adaptive optics (AO) can be used to compensate ocular aberrations when using high numerical aperture (NA), and thus improve image resolution. However, previously reported AO-OCTA instruments were large and complex, and have a small sub-millimeter field of view (FOV) that hinders the extraction of biomarkers with ...
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    14. Depth-resolved optimization of a real-time sensorless adaptive optics optical coherence tomography

      Depth-resolved optimization of a real-time sensorless adaptive optics optical coherence tomography
      Sensorless adaptive optics optical coherence tomography (AO-OCT) is a technology to image retinal tissue with high resolution by compensating ocular aberrations without wavefront sensors. In this Letter, a fast and robust hill-climbing algorithm is developed to optimize five Zernike modes in AO-OCT with a numerical aperture between that of conventional AO and commercial OCT systems. The merit function is generated in real time using graphics processing unit while axially tracking ...
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    15. Optical coherence tomography angiography avascular area association with one-year treatment requirement and disease progression in diabetic retinopathy

      Optical coherence tomography angiography avascular area association with one-year treatment requirement and disease progression in diabetic retinopathy
      Purpose To assess the association between optical coherence tomography angiography (OCTA) quantified avascular areas (AA) and diabetic retinopathy (DR) severity, progression and treatment requirement in the following year. Design Prospective cohort study. Methods We recruited diabetic patients from tertiary academic retina practice and obtained 3x3-mm macular OCTA scans with AngioVue system and standard 7-field color photographs at baseline and 1-year visit. A masked grader determined the DR severity from the ...
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    16. 1-15 of 314 1 2 3 4 ... 19 20 21 »
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  2. About Center for Ophthalmic Optics and Lasers

    Center for Ophthalmic Optics and Lasers

    The Center for Ophthalmic Optics and Lasers (COOL) at Doheny Eye Institute, University of Southern California (USC) is a state of the art research center focusing on the application of biomedical optics in clinical medicine. COOL lab emcompass an extensive range of research areas in both optics and ophthalmology. The mission of the center is to: "Conserve, improve and restore vision through advances in laser and optical technology".