1. Center for Ophthalmic Optics and Lasers

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    1. Mentioned In 329 Articles

    2. High speed, long range, deep penetration swept source OCT for structural and angiographic imaging of the anterior eye

      High speed, long range, deep penetration swept source OCT for structural and angiographic imaging of the anterior eye
      This study reports the development of prototype swept-source optical coherence tomography (SS-OCT) technology for imaging the anterior eye. Advances in vertical-cavity surface-emitting laser (VCSEL) light sources, signal processing, optics and mechanical designs, enable a unique combination of high speed, long range, and deep penetration that addresses the challenges of anterior eye imaging. We demonstrate SS-OCT with a 325 kHz A-scan rate, 12.2 m axial resolution (in air), and 15 ...
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    3. Volumetric directional optical coherence tomography

      Volumetric directional optical coherence tomography
      Photoreceptor loss and resultant thinning of the outer nuclear layer (ONL) is an important pathological feature of retinal degenerations and may serve as a useful imaging biomarker for age-related macular degeneration. However, the demarcation between the ONL and the adjacent Henles fiber layer (HFL) is difficult to visualize with standard optical coherence tomography (OCT). A dedicated OCT system that can precisely control and continuously and synchronously update the imaging beam ...
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    4. Prospective evaluation of optical coherence tomography for disease detection in the Casey mobile eye clinic

      Prospective evaluation of optical coherence tomography for disease detection in the Casey mobile eye clinic
      This study was designed to evaluate iVue Spectral-domain optical coherence tomography (SD-OCT) effectiveness in screening for eye disease compared to clinical examination. Subjects were recruited from the Casey Eye Community Outreach Program Mobile Clinic during its routinely scheduled outreach clinics to indigent, underserved populations throughout Oregon. Macular optical coherence tomography interpretation and automated optical coherence tomography analysis were compared to the clinical examination, with specific attention to findings indicative of ...
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    5. Oregon Health and Science University Receives NIH Grant for OCT Angiography for Neovascular Age-related Macular Degeneration

      Oregon Health and Science University Receives NIH Grant for OCT Angiography for Neovascular Age-related Macular Degeneration
      Oregon Health and Science University Receives a 2021 NIH Grant for $471,602 for OCT Angiography for Neovascular Age-related Macular Degeneration. The principal investigator is Yali Jia. Below is a summary of the proposed work. Neovascular age-related macular degeneration (AMD), characterized by the presence of choroidal neovascularization (CNV), accounts for the majority of AMD related vision loss. Invasive dye-based fluorescein angiography (FA) remains the gold standard for CNV detection. Using ...
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    6. Optical coherence tomographic angiography study of perfusion recovery after surgical lowering of intraocular pressure

      Optical coherence tomographic angiography study of perfusion recovery after surgical lowering of intraocular pressure
      We investigated the time and location of retinal perfusion recovery after surgical intraocular pressure (IOP) lowering in glaucoma by using optical coherent tomography angiography (OCTA). Seventeen patients were analyzed. The 4.54.5-mm OCTA scans centered on the disc were performed preoperatively and postoperatively at 6 weeks, 3 months, and 6 months. The peripapillary retinal nerve fiber layer (NFL) thickness, NFL plexus capillary density (NFLP-CD) and visual field (VF) were ...
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    7. Normative intercapillary distance and vessel density data in the temporal retina assessed by wide-field spectral-domain optical coherence tomography angiography

      Normative intercapillary distance and vessel density data in the temporal retina assessed by wide-field spectral-domain optical coherence tomography angiography
      A limitation of conventional optical coherence tomography angiography (OCTA) is the limited field of view normally used in data acquisition. As the technology improves, larger fields of view that capture information away from the macular are being explored in order to provide an enhanced ability to detect pathology. However, normative measurements for important OCTA metrics like vessel density and intercapillary distance are not currently well-characterized in the peripheral retina. In ...
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    8. Accuracy of OCT-derived net corneal astigmatism measurement

      Accuracy of OCT-derived net corneal astigmatism measurement
      Purpose: To assess the repeatability and accuracy of corneal astigmatism measurement with a spectral-domain optical coherence tomography (OCT) system (Avanti, Optovue) and compare them with Scheimpflug imaging (Pentacam HR, Oculus) and swept-source optical biometry (IOLMaster 700, Carl Zeiss Mediatec AG). Setting: Casey Eye Institute, Oregon Health Science University, Portland, Oregon, USA. Design: Prospective cross-sectional observational study. Methods: Sixty pseudophakic eyes with monofocal non-toric intraocular lens that previously had refractive surgery ...
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    9. Effect of algorithms and covariates in glaucoma diagnosis with optical coherence tomography angiography

      Effect of algorithms and covariates in glaucoma diagnosis with optical coherence tomography angiography
      Purpose: To assess the effects of algorithms and covariates in glaucoma diagnosis with optical coherence tomography angiography (OCTA). Methods: In this prospective cross-sectional study, one eye each of 36 normal controls and 64 patients with glaucoma underwent 4.5 mm disc-centred and 6 mm macula-centred OCTA scans. The peripapillary nerve fibre layer plexus capillary density (NFLP-CD) and macular superficial vascular complex vessel density (SVC-VD) were measured using both a commercial ...
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    10. Oregon Health and Science University Receives NIH Grant for Optical Coherence Tomography-Aided Differential Diagnosis and Treatment of Irregular Corneas

      Oregon Health and Science University Receives NIH Grant for Optical Coherence Tomography-Aided Differential Diagnosis and Treatment of Irregular Corneas
      Oregon Health and Science University Receives a 2021 NIH Grant for $373,450 for Optical Coherence Tomography-Aided Differential Diagnosis and Treatment of Irregular Corneas. The principal investigator is Yan Li. Below is a summary of the proposed work. To see well, the cornea must maintain near perfect clarity and shape. Several disease processes can distort corneal shape and degrade vision. These include ectasia/keratoconus (stromal thinning and bulging), primary epithelial ...
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    11. DcardNet: Diabetic Retinopathy Classification at Multiple Levels Based on Structural and Angiographic Optical Coherence Tomography

      DcardNet: Diabetic Retinopathy Classification at Multiple Levels Based on Structural and Angiographic Optical Coherence Tomography
      Objective: Optical coherence tomography (OCT) and its angiography (OCTA) have several advantages for the early detection and diagnosis of diabetic retinopathy (DR). However, automated, complete DR classification frameworks based on both OCT and OCTA data have not been proposed. In this study, a convolutional neural network (CNN) based method is proposed to fulfill a DR classification framework using en face OCT and OCTA.
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    12. High-speed and widefield handheld swept-source OCT angiography with a VCSEL light source

      High-speed and widefield handheld swept-source OCT angiography with a VCSEL light source
      Optical coherence tomography (OCT) and OCT angiography (OCTA) enable noninvasive structural and angiographic imaging of the eye. Portable handheld OCT/OCTA systems are required for imaging patients in the supine position. Examples include infants in the neonatal intensive care unit (NICU) and operating room (OR). The speed of image acquisition plays a pivotal role in acquiring high-quality OCT/OCTA images, particularly with the handheld system, since both the operator hand ...
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    13. OHSU Receives NIH Grant for Artificial Intelligence Assisted Panoramic Optical Coherence Tomography Angiography for Retinopathy of Prematurity

      OHSU Receives NIH Grant for Artificial Intelligence Assisted Panoramic Optical Coherence Tomography Angiography for Retinopathy of Prematurity
      Oregon Health and Science University Receives a 2021 NIH Grant for $377,300 for Artificial Intelligence Assisted Panoramic Optical Coherence Tomography Angiography for Retinopathy of Prematurity. The principal investigator is Yifan Jian. Below is a summary of the proposed work. The long-term goal of this project is to determine whether optical coherence tomography (OCT) and OCT angiography (OCTA) might lead more accurate and objective diagnosis, earlier intervention, and improved outcomes ...
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    14. Phase-stabilized complex-decorrelation angiography

      Phase-stabilized complex-decorrelation angiography
      In this study, we developed a novel phase-stabilized complex-decorrelation (PSCD) optical coherence tomography (OCT) angiography (OCTA) method that can generate high quality OCTA images. This method has been validated using three different types of OCT systems and compared with conventional complex- and amplitude-based OCTA algorithms. Our results suggest that in combination with a pre-processing phase stabilization method, the PSCD method is insensitive to bulk motion phase shifts, less dependent on ...
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    15. Comparison of Central Macular Fluid Volume With Central Subfield Thickness in Patients With Diabetic Macular Edema Using Optical Coherence Tomography Angiography

      Comparison of Central Macular Fluid Volume With Central Subfield Thickness in Patients With Diabetic Macular Edema Using Optical Coherence Tomography Angiography
      Importance: Diabetic macular edema (DME) is the predominant cause of visual impairment in patients with type 1 or 2 diabetes. Automated fluid volume measurements using optical coherence tomography (OCT) may improve the diagnostic accuracy of DME screening. Objective: To assess the diagnostic accuracy of an automated central macular fluid volume (CMFV) quantification using OCT for DME. Design, setting, and participants: A cross-sectional observational study was conducted at a tertiary academic ...
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    16. Postdoctoral Research Fellowship position in the Center for Ophthalmic Optics and Lasers, Casey Eye Institute, Oregon Health & Science University

      Postdoctoral Research Fellowship position  in the Center for Ophthalmic Optics and Lasers, Casey Eye Institute, Oregon Health & Science University
      ... is to conserve, improve and restore vision through advances in laser and optical technology. Description The Center for Ophthalmic Optics and Lasers (COOL) at the Casey Eye Institute, Oregon Health Science University i...
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    17. 1-15 of 329 1 2 3 4 ... 20 21 22 »
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  2. About Center for Ophthalmic Optics and Lasers

    Center for Ophthalmic Optics and Lasers

    The Center for Ophthalmic Optics and Lasers (COOL) at Doheny Eye Institute, University of Southern California (USC) is a state of the art research center focusing on the application of biomedical optics in clinical medicine. COOL lab emcompass an extensive range of research areas in both optics and ophthalmology. The mission of the center is to: "Conserve, improve and restore vision through advances in laser and optical technology".