1. Center for Ophthalmic Optics and Lasers

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    1. Mentioned In 277 Articles

    2. Signal strength reduction effects in optical coherence tomographic angiography

      Signal strength reduction effects in optical coherence tomographic angiography
      Objective To elucidate the relationship between vessel density (VD) measurements and signal strength in optical coherence tomography angiography (OCTA). Design Cross-sectional study. Subjects: Healthy volunteers. Methods OCTA images obtained from healthy volunteers were analyzed to demonstrate the relationship between signal strength index (SSI) and VD. Experiments were performed to determine the effects of signal strength reduction on VD measurements on the Optovue/AngioVue and Cirrus/AngioPlex OCTA systems. Signal strength ...
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    3. Maximum value projection produces better en face OCT angiograms than mean value projection

      Maximum value projection produces better en face OCT angiograms than mean value projection
      Optical coherence tomography angiography (OCTA) images rely on en face data projections for both qualitative and quantitative interpretation. Both maximum value and mean value projections are commonly used, and many researchers consider them essentially interchangeable approaches. On the contrary, we find that maximum value projection achieves a consistently higher signal-to-noise ratio and higher image contrast across multiple vascular layers, in both healthy eyes and for each disease examined.
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    4. David Huang Listed on Ophthalmologist Magazine's 2019 Power List as #1 Inventor!

      David Huang Listed on Ophthalmologist Magazine's 2019 Power List as #1 Inventor!
      We are delighted to share The Ophthalmologists Power List 2019 with you. This year saw a record number of nominations almost 2,000 across five categories: Champions for Change, Inventors, Emerging Leaders, Mentors, and Surgical Pioneers. Each nomination celebrates an individual who has made a significant impact on the field, whether that is through a philanthropic initiative or their ongoing commitment to innovation. The diversity of the categories and the ...
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    5. Detection of Non-exudative Choroidal Neovascularization and Progression to Exudative Choroidal Neovascularization Using Optical Coherence Tomography Angiography

      Detection of Non-exudative Choroidal Neovascularization and Progression to Exudative Choroidal Neovascularization Using Optical Coherence Tomography Angiography
      Objective To detect non-exudative choroidal neovascularization (CNV) in age-related macular degeneration with optical coherence tomography angiography (OCTA) and determine risk of developing exudative CNV compared to eyes without non-exudative CNV. Design Prospective longitudinal observational study Participants Consecutive patients with drusen and pigmentary changes in the study eye and exudative neovascular AMD in the fellow eye. Methods Study participants underwent spectral domain OCTA (AngioVue, Optovue, Inc), clinical exam, and structural OCT ...
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    6. Systems and methods to remove shadowgraphic flow projections in OCT angiography

      Systems and methods to remove shadowgraphic flow projections in OCT angiography
      Methods and systems for suppressing shadowgraphic flow projection artifacts in OCT angiography images of a sample are disclosed. In one example approach, normalized OCT angiography data is analyzed at the level of individual A-scans to classify signals as either flow or projection artifact. This classification information is then used to suppress projection artifacts in the three dimensional OCT angiography dataset.
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    7. Real-time cross-sectional and en face OCT angiography guiding high-quality scan acquisition

      Real-time cross-sectional and en face OCT angiography guiding high-quality scan acquisition
      Defocusing, vignetting, and bulk motion degrade the image quality of optical coherence tomography angiography (OCTA) more significantly than structural OCT. The assessment of focus, alignment conditions, and stability of imaging subjects in commercially available OCTA systems are currently based on OCT signal quality alone, without knowledge of OCTA signal quality. This results in low yield rates for further quantification. In this Letter, we developed a novel OCTA platform based on ...
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    8. Visual Optics Postdoctoral/Research Fellow Opening at Oregon Health & Science University

      Visual Optics Postdoctoral/Research Fellow Opening at Oregon Health & Science University
      A postdoctoral research fellow position is available in the Center for Ophthalmic Optics Lasers Lab ( www.coollab.net ), Casey Eye Institute, Oregon Health Science University. This is an outstanding opportunity for a candidate to use optical coherence tomography to conduct visual optics research in an academic ophthalmology setting. The researcher on this position will work with a team of scientists, engineers and physicians to develop ultrahigh-performance OCT systems for comprehensive ...
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    9. DETECTION OF CLINICALLY UNSUSPECTED RETINAL NEOVASCULARIZATION WITH WIDE-FIELD OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY

      DETECTION OF CLINICALLY UNSUSPECTED RETINAL NEOVASCULARIZATION WITH WIDE-FIELD OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY
      Purpose: To evaluate wide-field optical coherence tomography angiography (OCTA) for detection of clinically unsuspected neovascularization (NV) in diabetic retinopathy (DR). Methods: This prospective observational single-center study included adult patients with a clinical diagnosis of nonproliferative DR. Participants underwent a clinical examination, standard 7-field color photography, and OCTA with commercial and prototype swept-source devices. The wide-field OCTA was achieved by montaging five 6 10-mm scans from a prototype device into a ...
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    10. OSHU Receives NIH Grant for Applications of Ultrahigh-Speed Long-Range Wide-Field OCT in Anterior Eye Diseases

      OSHU Receives NIH Grant for Applications of Ultrahigh-Speed Long-Range Wide-Field OCT in Anterior Eye Diseases
      Oregon Health Science University Receives a 2019 NIH Grant for $496,687 for Applications of Ultrahigh-Speed Long-Range Wide-Field OCT in Anterior Eye Diseases. The principal investigator is David Huang. The program began in 2018 and ends in 2023. Below is a summary of the proposed work. Optical coherence tomography (OCT) is uniquely able to achieve micron depth resolution while imaging a large 3-dimensional (3D) volume. This enables 3D imaging and ...
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    11. Systems and methods for retinal layer segmentation in OCT imaging and OCT angiography

      Systems and methods for retinal layer segmentation in OCT imaging and OCT angiography
      Disclosed herein are methods and systems for segmenting, visualizing, and quantifying the layered structure of retina in optical coherence tomography datasets. The disclosed methods have particular application to OCT angiography data, where specific retina layers have distinct vascular structures and characteristics that can be altered in various pathological conditions of the eye.
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    12. Rodent retinal circulation organization and oxygen metabolism revealed by visible-light optical coherence tomography

      Rodent retinal circulation organization and oxygen metabolism revealed by visible-light optical coherence tomography
      Visible light optical coherence tomography (vis-OCT) is an emerging label-free and high-resolution 3-dimensional imaging technique that can provide retinal oximetry, angiography, and flowmetry in one modality. In this paper, we studied the organization of the arterial and venous retinal circulation in rats using vis-OCT. Arterioles were found predominantly in the superficial vascular plexus whereas veins tended to drain capillaries from the deep capillary plexus. After that, we determined the oxygen ...
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    13. Quantitative evaluation of retinal artery occlusion using optical coherence tomography angiography: A case report

      Quantitative evaluation of retinal artery occlusion using optical coherence tomography angiography: A case report
      Rationale: Retinal artery occlusion (RAO) results in painless, catastrophic vision loss in a period of seconds. Optical coherence tomography angiography (OCTA) can image retinal microcirculation, which is helpful to evaluate treatment response during the follow-up period. Using a single case with central RAO, we report its retinal perfusion changes before and after treatment using OCTA. Patient concerns: A 36-year-old Chinese man came to our clinic with a sudden, painless loss ...
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    14. Postdoctoral Fellowship/Research Associate Position at the Casey Eye Institute, Oregon Health & Science University

      Postdoctoral Fellowship/Research Associate Position at the Casey Eye Institute, Oregon Health & Science University
      ... be submitted. A postdoctoral research fellowship/research associate position is immediately available in the Center for Ophthalmic Optics and Lasers www.COOLLab.net, Casey Eye Institute, Oregon Health & Science Universi...
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    15. 1-15 of 277 1 2 3 4 ... 17 18 19 »
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  2. About Center for Ophthalmic Optics and Lasers

    Center for Ophthalmic Optics and Lasers

    The Center for Ophthalmic Optics and Lasers (COOL) at Doheny Eye Institute, University of Southern California (USC) is a state of the art research center focusing on the application of biomedical optics in clinical medicine. COOL lab emcompass an extensive range of research areas in both optics and ophthalmology. The mission of the center is to: "Conserve, improve and restore vision through advances in laser and optical technology".