1. Center for Ophthalmic Optics and Lasers

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    1. Mentioned In 344 Articles

    2. Association of Optical Coherence Tomography–Measured Fibrovascular Ridge Thickness and Clinical Disease Stage in Retinopathy of Prematurity

      Association of Optical Coherence Tomography–Measured Fibrovascular Ridge Thickness and Clinical Disease Stage in Retinopathy of Prematurity
      Importance Accurate diagnosis of retinopathy of prematurity (ROP) is essential to provide timely treatment and reduce the risk of blindness. However, the components of an ROP examination are subjective and qualitative. Objective To evaluate whether optical coherence tomography (OCT)derived retinal thickness measurements at the vascular-avascular junction are associated with clinical diagnosis of ROP stage. Design, Setting, and Participants This cross-sectional longitudinal study compared OCT-based ridge thickness calculated from OCT ...
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    3. Volume-based, layer-independent, disease-agnostic detection of abnormal retinal reflectivity, nonperfusion, and neovascularization using structural and angiographic OCT

      Volume-based, layer-independent, disease-agnostic detection of abnormal retinal reflectivity, nonperfusion, and neovascularization using structural and angiographic OCT
      Optical coherence tomography (OCT) is widely used in ophthalmic practice because it can visualize retinal structure and vasculature in vivo and 3-dimensionally (3D). Even though OCT procedures yield data volumes, clinicians typically interpret the 3D images using two-dimensional (2D) data subsets, such as cross-sectional scans or en face projections. Since a single OCT volume can contain hundreds of cross-sections (each of which must be processed with retinal layer segmentation to ...
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    4. Systems and methods for automated widefield optical coherence tomography angiography

      Systems and methods for automated widefield optical coherence tomography angiography
      Disclosed are systems and methods for generating wide-field optical coherence tomography angiography (OCTA) images. In embodiments, multiple OCTA scans of a sample are automatically acquired at overlapping locations. The systems and methods include functionality to adaptively control the scanning procedure such that eye blink and eye motion events are detected in real time and accounted for during 3D scan acquisition. Also disclosed are methods for detecting and correcting motion-related artifacts ...
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    5. Regression-Based Strategies to Reduce Refractive Error-Associated Glaucoma Diagnostic Bias When Using OCT and OCT Angiography

      Regression-Based Strategies to Reduce Refractive Error-Associated Glaucoma Diagnostic Bias When Using OCT and OCT Angiography
      Purpose : The purpose of this study was to correct refractive error-associated bias in optical coherence tomography (OCT) and OCT angiography (OCTA) glaucoma diagnostic parameters. Methods : OCT and OCTA imaging were obtained from participants in the Hong Kong FAMILY cohort. The Avanti/AngioVue OCT/OCTA system was used to measure the peripapillary nerve fiber layer thickness (NFLT), peripapillary nerve fiber layer plexus capillary density (NFLP-CD), macular ganglion cell complex thickness (GCCT ...
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    6. Oregon Health & Science University Receives NIH Grant for Functional and Structural Optical Coherence Tomography for Glaucoma

      Oregon Health & Science University Receives NIH Grant for Functional and Structural Optical Coherence Tomography for Glaucoma
      Oregon Health Science University Received a 2022 NIH Grant for $590,490 for Functional and Structural Optical Coherence Tomography for Glaucoma . The principal investigator is David Huang. Below is a summary of the proposed work. Glaucoma is a leading cause of blindness in the US. The management of glaucoma is based on early detection, followed by careful evaluation and monitoring to identify those with rapid disease progression and high risk ...
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    7. Corneal imaging with blue-light optical coherence microscopy

      Corneal imaging with blue-light optical coherence microscopy
      Corneal imaging is important for the diagnostic and therapeutic evaluation of many eye diseases. Optical coherence tomography (OCT) is extensively used in ocular imaging due to its non-invasive and high-resolution volumetric imaging characteristics. Optical coherence microscopy (OCM) is a technical variation of OCT that can image the cornea with cellular resolution. Here, we demonstrate a blue-light OCM as a low-cost and easily reproducible system to visualize corneal cellular structures such ...
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    8. Detection of Corneal Ectasia Using OCT Maps of Pachymetry and Posterior Surface Mean Curvature

      Detection of Corneal Ectasia Using OCT Maps of Pachymetry and Posterior Surface Mean Curvature
      Purpose: To quantify the abnormal corneal thinning and posterior surface steepening that is observed in keratoconus with an Ectasia Index. Methods: Optical coherence tomography (OCT) was used to image the corneas of normal individuals and patients with varying stages of keratoconus (manifest, subclinical, and forme fruste). Maps of corneal pachymetry and posterior surface mean curvature were generated, and an Ectasia Index was calculated by multiplying Gaussian fits obtained from the ...
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    9. Widefield Optical Coherence Tomography in Pediatric Retina: A Case Series of Intraoperative Applications Using a Prototype Handheld Device

      Widefield Optical Coherence Tomography in Pediatric Retina: A Case Series of Intraoperative Applications Using a Prototype Handheld Device
      Optical coherence tomography (OCT) has changed the standard of care for diagnosis and management of macular diseases in adults. Current commercially available OCT systems, including handheld OCT for pediatric use, have a relatively narrow field of view (FOV), which has limited the potential application of OCT to retinal diseases with primarily peripheral pathology, including many of the most common pediatric retinal conditions. More broadly, diagnosis of all types of retinal ...
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    10. A Diabetic Retinopathy Classification Framework Based on Deep-Learning Analysis of OCT Angiography

      A Diabetic Retinopathy Classification Framework Based on Deep-Learning Analysis of OCT Angiography
      Purpose : Reliable classification of referable and vision threatening diabetic retinopathy (DR) is essential for patients with diabetes to prevent blindness. Optical coherence tomography (OCT) and its angiography (OCTA) have several advantages over fundus photographs. We evaluated a deep-learning-aided DR classification framework using volumetric OCT and OCTA. Methods : Four hundred fifty-six OCT and OCTA volumes were scanned from eyes of 50 healthy participants and 305 patients with diabetes. Retina specialists labeled ...
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    11. Measuring Corneal Astigmatism Using Optical Coherence Tomography in Keratoconus

      Measuring Corneal Astigmatism Using Optical Coherence Tomography in Keratoconus
      Purpose: To measure net corneal astigmatism using optical coherence tomography (OCT, Avanti, Optovue) in individuals with keratoconus and compare its repeatability and accuracy with those obtained using Scheimpflug imaging (Pentacam HR, Oculus). Setting: Casey Eye Institute, Portland, Oregon, USA. Design: Prospective cross-sectional observational study. Methods: Net corneal astigmatism was calculated in keratoconic and normal eyes with OCT and Scheimpflug imaging using four settings - pupil or vertex centration settings with a ...
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    12. Postdoctoral Research Fellowship in Anterior Eye OCT Image Processing and Machine Learning at Oregon Health & Science University.

      Postdoctoral Research Fellowship in Anterior Eye OCT Image Processing and Machine Learning at Oregon Health & Science University.
      A postdoctoral research fellow position is immediately available in the Center for Ophthalmic Optics Lasers Lab ( www.coollab.net ), Casey Eye Institute, Oregon Health Science University. The fellowship will focus on interdisciplinary projects in the field of biomedical image processing, visual optics, and machine learning. PhD in Biomedical Engineering, Electrical Engineering, Computer Science, Optics, or related field of research is required. The position is supported by NIH/NEI research grants ...
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    13. Differentiating Between Contact Lens Warpage and Keratoconus Using OCT Maps of Corneal Mean Curvature and Epithelial Thickness

      Differentiating Between Contact Lens Warpage and Keratoconus Using OCT Maps of Corneal Mean Curvature and Epithelial Thickness
      Purpose: To formulate an Epithelial Modulation index to differentiate between eyes with contact lens warpage and keratoconus. Methods: Normal eyes and eyes with either contact lens warpage or keratoconus were scanned by a Fourier-domain optical coherence tomography (OCT) system. Maps of epithelial thickness and anterior surface mean curvature were generated and converted to deviation maps by subtracting the average maps from a healthy population. The Epithelial Modulation index was defined ...
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    14. Peripheral OCT Assisted by Scleral Depression in Retinopathy of Prematurity

      Peripheral OCT Assisted by Scleral Depression in Retinopathy of Prematurity
      Objective: To determine whether handheld widefield optical coherence tomography (OCT) can be used to document retinopathy of prematurity (ROP) stage while using scleral depression to improve peripheral views. Design: Prospective observational study. Participants: Consecutive neonates admitted to the neonatal intensive care unit (NICU) in a single academic medical center who also met criteria for ROP screening and consented for research imaging. Methods: Scleral depression was combined with widefield OCT using ...
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    15. Advantages of Widefield Optical Coherence Tomography in the Diagnosis of Retinopathy of Prematurity

      Advantages of Widefield Optical Coherence Tomography in the Diagnosis of Retinopathy of Prematurity
      Recent advances in portable optical coherence tomography (OCT) and OCT angiography (OCTA) have resulted in wider fields of view (FOV) and shorter capture times, further expanding the potential clinical role of OCT technology in the diagnosis and management of retinopathy of prematurity (ROP). Using a prototype, handheld OCT device, retinal imaging was obtained in non-sedated infants in the neonatal intensive care unit (NICU) as well as sedated infants in the ...
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    16. 1-15 of 344 1 2 3 4 ... 21 22 23 »
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  2. About Center for Ophthalmic Optics and Lasers

    Center for Ophthalmic Optics and Lasers

    The Center for Ophthalmic Optics and Lasers (COOL) at Doheny Eye Institute, University of Southern California (USC) is a state of the art research center focusing on the application of biomedical optics in clinical medicine. COOL lab emcompass an extensive range of research areas in both optics and ophthalmology. The mission of the center is to: "Conserve, improve and restore vision through advances in laser and optical technology".