Articles that mention Case Western Reserve University -Optical Coherence Tomography News

Case Western Reserve University

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1. Mentioned In 295 Articles
2. Case Western Reserve University Receives NIH Grant for Optical Tools to Assess the Role of Hemodynamics in the Development of Congenital Heart Defects
  
  Explore Optical Coherence Tomography News Jul 11 2019 Developmental Biology , Funding
  
  ...arlier detection strategies, and potentially to treat CHDs more effectively .
  Case Western Reserve University Receives a 2019 NIH Grant for $493,857 for Optical Tools to Assess the Role of...
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  Mentions: Case Western Reserve University Michael W. Jenkins
3. The impact of blood pressure variability on coronary arterial lumen dimensions as assessed by optical coherence tomography in patients with ST-elevation myocardial infarction
  
  Explore ScienceDirect Jun 25 2019 Cardiology
  
  Background Patients with ST-elevation Myocardial Infarction treated by primary percutaneous coronary intervention (PPCI) experience drastic hemodynamic systemic changes (i.e., blood pressure) during the different phases of the procedure. Optical coherence tomography is often used to unveil the underlying cause of STEMI (pre-PCI) and to optimize stent implantation (post-PCI). The impact of blood pressure variability on coronary lumen remains uncertain. This study aimed to investigate the relationship between blood pressure ...
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  Mentions: Case Western Reserve University Leiden University Hector M. Garcia-Garcia
4. Case Western Reserve University Receives NIH Grant for Noninvasive Assessment of the Cornea by Diffusion OCT
  
  Explore Optical Coherence Tomography News Jun 25 2019 Ophthalmology , Funding
  
  ...ft from empirical planning and risk analysis to patient-specific strategies .
  Case Western Reserve University Receives a 2019 NIH Grant for $396,887 for Noninvasive Assessment of the Corne...
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  Mentions: Andrew M. Rollins National Institutes of Health Case Western Reserve University
5. Diagnostic accuracy of intracoronary optical coherence tomography-derived fractional flow reserve for assessment of coronary stenosis severity
  
  Explore eurointervention.pcronline.com Jun 6 2019 Cardiology
  
  $Diagnostic accuracy of intracoronary optical coherence tomography-derived fractional flow reserve for assessment of coronary stenosis severity$
  ims: A novel method for computation of fractional flow reserve (FFR) from optical coherence tomography (OCT) was developed recently. This study aimed to evaluate the diagnostic accuracy of a new OCT-based FFR (OFR) computational approach, using wire-based FFR as the reference standard. Methods and results: Patients who underwent both OCT and FFR prior to intervention were analysed. The lumen of the interrogated vessel and the ostia of the side branches ...
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  Mentions: Case Western Reserve University Capital Medical University Shanghai Jiao Tong University
6. Case Western Reserve University Receives NIH Grant for Computer Assisted Coronary Artery Stent Interventions
  
  Explore Optical Coherence Tomography News Jun 4 2019 Cardiology , Funding
  
  ...ll build on expertise in interventions, quantitative image analysis of IVOCT, and finite element modeling.
  Case Western Reserve University Receives a 2019 NIH Grant for $732,934 for Computer Assisted Coronary Artery S...
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  Mentions: National Institutes of Health Case Western Reserve University David L. Wilson
7. Title Automated Plaque Characterization of Intravascular Optical Coherence Tomography (IVOCT) Images Using 3D Cryo-image/Histology Validation (Thesis)
  
  Explore OhioLINK ETD Center May 28 2019 Cardiology , Student Theses
  
  Intravascular optical coherence tomography (IVOCT) is a high-resolution (10-20 m), high-contrast, catheter-based imaging technology that can identify major coronary plaques types (fibrous, lipid, and calcium). However, with 500 images generated in a single 2.5 second scan, automation is needed to facilitate live-time clinical use and off-line assessment of drug therapeutics. Therefore, we developed machine learning approaches for automated plaque characterization using cryo-imaging/histology for validation. However, we confronted a ...
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  Mentions: Case Western Reserve University
8. Automated analysis of intravascular OCT image volumes
  
  Explore uspto.gov Mar 12 2019 Cardiology , Patents
  
  This disclosure provides systems and methods to automatically classify stent struts as covered or uncovered and to measure the thickness of tissue coverage. As one example, the method includes storing three-dimensional image data acquired intravascularly via an optical coherence tomography (OCT) apparatus and detecting struts based on analysis of the image data. Image data corresponding to each of the detected struts is further analyzed automatically to compute an indication of ...
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  Mentions: Case Western Reserve University David L. Wilson Hiram G. Bezerra
9. Early hydroxychloroquine retinopathy: optical coherence tomography abnormalities preceding Humphrey visual field defects
  
  Explore BJO Online Mar 6 2019 Ophthalmology
  
  Background/Aims Hydroxychloroquine (HCQ) retinopathy may result in severe and irreversible vision loss, emphasising the importance of screening and early detection. The purpose of this study is to report the novel finding of early optical coherence tomography (OCT) abnormalities due to HCQ toxicity that may develop in the setting of normal Humphrey visual field (HVF) testing. Methods Data from patients with chronic HCQ exposure was obtained from seven tertiary care ...
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  Mentions: Case Western Reserve University Jay S. Duker LuEsther T. Mertz Retinal Research Center
10. Analysis of optical tomography (OCT) images
  
  Explore uspto.gov Feb 26 2019 Cardiology , Patents
  
  A method includes storing three-dimensional image data acquired intravascularly via an optical coherence tomography (OCT) apparatus. The image data is analyzed to compute a probability estimate of stent presence at support positions appearing in an A-line. Stent strut locations are located in three-dimensional space based on the computed probability estimate of stent presence.
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  Mentions: Andrew M. Rollins Case Western Reserve University Zhao Wang
11. SLIME: robust, high-speed 3D microvascular mapping
  
  Explore Nature Publishing Group Feb 3 2019
  
  Three dimensional (3D) microvascular imaging of cubic millimeter to centimeter size volumes often requires much time and expensive instruments. By combining optical clearing with a novel scatter-based optical coherence tomography (OCT) contrast agent, we have greatly extended OCT imaging depth in excised tissues while maintaining a simple and low cost approach that does not require in-depth OCT knowledge. The new method enables fast 3D microvascular mapping in large tissue volumes ...
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  Mentions: Andrew M. Rollins Case Western Reserve University Michael W. Jenkins
12. Feasibility of a porcine arteriovenous shunt model for assessment of acute thrombogenicity in bifurcation stenting technique by optical coherence tomography
  
  Explore ScienceDirect Jan 8 2019 Cardiology
  
  Background Double kissing (DK) crush stenting has been reported as a superior bifurcation stenting strategy compared to culotte stenting. However, the mechanism associated with the reduction of clinical events by DK crush stenting remains unclear. We therefore investigated the thrombogenicity of DK crush stenting and culotte stenting with both bare-metal stents (BMS) and drug-eluting stents (DES) and the feasibility of a novel porcine arteriovenous shunt model. Methods High-resolution intracoronary imaging ...
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  Mentions: Case Western Reserve University Hector M. Garcia-Garcia Ron Waksman
13. Noninvasive Assessment of Corneal Crosslinking With Phase-Decorrelation Optical Coherence Tomography
  
  Explore IOVS Journal Jan 8 2019 Ophthalmology
  
  Purpose : There is strong evidence that abnormalities in corneal biomechanical play a causal role in corneal ectasias, such as keratoconus. Additionally, corneal crosslinking (CXL) treatment, which halts progression of keratoconus, directly appeals to corneal biomechanics. However, existing methods of corneal biomechanical assessment have various drawbacks: dependence on IOP, long acquisition times, or limited resolution. Here, we present a method that may avoid these limitations by using optical coherence tomography (OCT ...
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  Mentions: Andrew M. Rollins Case Western Reserve University Michael W. Jenkins
14. Serial 3-Dimensional Optical Coherence Tomography Assessment of Jailed Side-Branch by Second-Generation Drug-Eluting Absorbable Metal Scaffold (From the BIOSOLVE-II Trial)
  
  Explore American Journal of Cardiology Jan 4 2019 Cardiology
  
  Second-generation drug-eluting absorbable metal scaffold (DREAMS 2G) is used for treating coronary lesions. However, the natural history of the jailed side-branch (SB) after DREAMS 2G implantation remains to be elucidated. The aim of this study is to investigate the effect of scaffold struts on jailed SBs as assessed by 3-dimensional (3D) optical coherence tomography (OCT) after implantation of DREAMS 2G. We enrolled the patients who received a DREAMS 2G implantation ...
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  Mentions: Case Western Reserve University Hector M. Garcia-Garcia Wakayama Medical University
15. Impact of procedural characteristics on coronary vessel wall healing following implantation of second-generation drug-eluting absorbable metal scaffold in patients with de novo coronary artery lesions: an optical coherence tomography analysis
  
  Explore Journals Jan 1 2019 Cardiology
  
  Aims Second-generation drug-eluting absorbable metal scaffold (DREAMS 2G) is an alternative novel device for treating coronary lesions. However, the relationship between in-scaffold dimensions after implantation of DREAMS 2G and vessel healing and luminal results at follow-up is unknown. The aim of this study is, therefore, to investigate whether the expansion index after implantation of DREAMS 2G as assessed by optical coherence tomography (OCT) impacts late luminal status and healing of ...
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  Mentions: Case Western Reserve University Hector M. Garcia-Garcia Yuichi Ozaki
16. Deep neural networks for A-line-based plaque classification in coronary intravascular optical coherence tomography images
  
  Explore SPIE Digital Library Dec 8 2018 Cardiology
  
  We develop neural-network-based methods for classifying plaque types in clinical intravascular optical coherence tomography (IVOCT) images of coronary arteries. A single IVOCT pullback can consist of 500 microscopic-resolution images, creating both a challenge for physician interpretation during an interventional procedure and an opportunity for automated analysis. In the proposed method, we classify each A-line, a datum element that better captures physics and pathophysiology than a voxel, as a fibrous layer ...
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  Mentions: Case Western Reserve University Giulio Guagliumi David L. Wilson
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