1. Case Western Reserve University

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    1. Mentioned In 335 Articles

    2. Assessment of post-dilatation strategies for optimal stent expansion in calcified coronary lesions: Ex vivo analysis with optical coherence tomography

      Assessment of post-dilatation strategies for optimal stent expansion in calcified coronary lesions: Ex vivo analysis with optical coherence tomography
      Introduction: Interventional cardiologists make adjustments in the presence of coronary calcifications known to limit stent expansion, but proper balloon sizing, plaque-modification approaches, and high-pressure regimens are not well established. Intravascular optical coherence tomography (IVOCT) provides high-resolution images of coronary tissues, including detailed imaging of calcifications, and accurate measurements of stent deployment, providing a means for detailed study of stent deployment. Objective: Evaluate stent expansion in an ex vivo model of ...
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    3. Optical Coherence Tomography Findings in Infectious Posterior Uveitis

      Optical Coherence Tomography Findings in Infectious Posterior Uveitis
      Purpose To describe and illustrate the main optical coherence tomography (OCT) findings of infectious uveitis. Methods Narrative review. Results Posterior segment OCT in patients with infectious uveitis reveals posterior hyaloid face precipitates, superficial retinal precipitates and infiltrates, foveolitis, retinitis, neuro-retinitis, choroidal granulomas, and choroiditis as main imaging biomarkers. Some of these features are specific to the underlying causing etiology and may support the diagnosis and the initiation of treatment. Some ...
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    4. Recommendations for OCTA reporting in retinal vascular disease: A Delphi approach by International Experts

      Recommendations for OCTA reporting in retinal vascular disease: A Delphi approach by International Experts
      Purpose: To develop a consensus nomenclature for reporting optical coherence tomography angiography (OCTA) findings in retinal vascular disease (e.g., diabetic retinopathy, retinal vein occlusion) by international experts. Design: Delphi-based survey SUBJECTS, PARTICIPANTS AND/OR CONTROLS: Twenty-five retinal vascular disease and OCTA imaging experts METHODS, INTERVENTION, OR TESTING: A Delphi method of consensus development was used, comprising two rounds of online questionnaires, followed by a face-to-face meeting conducted virtually. Twenty-five ...
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    5. COMPUTATIONAL IMAGING AS APPLIED TO CORONARY ARTERY OPTICAL COHERENCE TOMOGRAPHY

      COMPUTATIONAL IMAGING AS APPLIED TO CORONARY ARTERY OPTICAL COHERENCE TOMOGRAPHY
      Patients with inadequate stent expansion are at high risk for adverse outcomes, including stent thrombosis as well as in-stent restenosis. Both are well-described complication usually causing acute coronary syndromes and, in the worst-case scenario, sudden cardiac death. Once a stent is deployed in atherosclerotic tissue that is highly resistant to dilation, it is often tricky to fully expand the implanted stent, even using a noncompliant balloon. Careful evaluation of these ...
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    6. Characterizing ablation lesions using optical coherence tomography (OCT)

      Characterizing ablation lesions using optical coherence tomography (OCT)
      Systems, methods, and other embodiments associated with characterizing Radio Frequency Ablation (RFA) lesions using Optical Coherence Tomography (OCT) are described. One example method includes acquiring an OCT signal from a Region Of Interest (ROI) in an ablated material. The example method may also include determining whether a lesion was formed by the ablation by analyzing optical properties of the ROI as recorded in the OCT signal.
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    7. Polarization-sensitive optical coherence tomography monitoring of percutaneous radiofrequency ablation in left atrium of living swine

      Polarization-sensitive optical coherence tomography monitoring of percutaneous radiofrequency ablation in left atrium of living swine
      Radiofrequency ablation (RFA) is commonly used to treat atrial fibrillation (AF). However, the outcome is often compromised due to the lack of direct real-time feedback to assess lesion transmurality. In this work, we evaluated the ability of polarization-sensitive optical coherence tomography (PSOCT) to measure cardiac wall thickness and assess RF lesion transmurality during left atrium (LA) RFA procedures. Quantitative transmural lesion criteria using PSOCT images were determined ex vivo using ...
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    8. Comparison of the Effect of Pan-Retinal Photocoagulation and Intravitreal Conbercept Treatment on the Change of Retinal Vessel Density Monitored by Optical Coherence Tomography Angiography in Patients with Proliferative Diabetic Retinopathy

      Comparison of the Effect of Pan-Retinal Photocoagulation and Intravitreal Conbercept Treatment on the Change of Retinal Vessel Density Monitored by Optical Coherence Tomography Angiography in Patients with Proliferative Diabetic Retinopathy
      Background: This study compares the change of retinal vessel density (VD) after pan-retinal photocoagulation (PRP) and intravitreal conbercept (IVC) treatment in proliferative diabetic retinopathy (PDR) eyes with optical coherence tomography angiography (OCTA). Methods: A total of 55 treatment-nave PDR eyes were included in this retrospective study. Of these, 29 eyes were divided into a PRP group, and 26 eyes were divided into an IVC group based on the treatment they ...
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    9. Case Western Reserve University ReceivesNIH Grant for Identifying and protecting alcohol-sensitive epigenetic changes in congenital heart disease

      Case Western Reserve University ReceivesNIH Grant for Identifying and protecting alcohol-sensitive epigenetic changes in congenital heart disease
      ...ls through structured mentorship, hands-on laboratory experiences, didactic teaching, and formal classwork at Case Western Reserve University, FAES at the NIH, and Jackson Laboratories. Dr. Michael Jenkins, a pioneer in ...
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    10. Case Western Reserve University Receives NIH Grant for Optically guided catheter ablation of atrial fibrillation

      Case Western Reserve University Receives NIH Grant for Optically guided catheter ablation of atrial fibrillation
      ...Dr. Marboe). Our team's long-term goal is to develop innovative technologies to improve AF ablation outcomes. Case Western Reserve University Receives a 2021 NIH Grant for $683,321 for Optically guided catheter ablation ...
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    11. Multi-Compartment Spatially-derived Radiomics from Optical Coherence Tomography Predict Anti-VEGF Treatment Durability in Macular Edema Secondary to Retinal Vascular Disease

      Multi-Compartment Spatially-derived Radiomics from Optical Coherence Tomography Predict Anti-VEGF Treatment Durability in Macular Edema Secondary to Retinal Vascular Disease
      Objective: Diabetic macular edema (DME) and retinal vein occlusion (RVO) are the leading causes of visual impairments across the world. Vascular endothelial growth factor (VEGF) stimulates breakdown of blood-retinal barrier that causes accumulation of fluid within macula. Anti-VEGF therapy is the first-line treatment for both the diseases; however, the degree of response varies for individual patients. The main objective of this work was to identify the (i) texture-based radiomics features ...
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    12. Phase-decorrelation optical coherence tomography-based parameter measurement

      Phase-decorrelation optical coherence tomography-based parameter measurement
      One example includes a scanning system. The system includes a phase-decorrelation optical coherence tomography (PhD-OCT) scanner configured to implement a scanning sequence via an optical signal on a sample medium. The system also includes a scanning controller configured to provide control signals to the PhD-OCT scanner to implement the scanning sequence and to obtain phase and amplitude information associated with a reflected version of the optical signal. The phase and ...
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    13. An en face swept source optical coherence tomography study of the vitreous in eyes with anterior uveitis

      An en face swept source optical coherence tomography study of the vitreous in eyes with anterior uveitis
      Purpose: To analyse vitreous anatomy patients with anterior uveitis (AU) using swept source optical coherence tomography (SS-OCT). Methods: Patients with newly diagnosed AU and healthy participants were scanned using 16-mm SS-OCT B-scans and 12 12 mm cube centred at the fovea. Linear SS-OCT scans were evaluated to identify the premacular bursa (PB) above the macula and the Cloquet's canal above the optic disc. A dynamic evaluation of the 12 ...
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    14. Prenatal ethanol exposure impairs the conduction delay at the atrioventricular junction in the looping heart

      Prenatal ethanol exposure impairs the conduction delay at the atrioventricular junction in the looping heart
      The etiology of ethanol-related congenital heart defects has been the focus of much study, but most research has concentrated on cellular and molecular mechanisms. We have shown with optical coherence tomography (OCT) that ethanol exposure led to increased retrograde flow and smaller atrioventricular (AV) cushions compared to controls. Since AV cushions play a role in patterning the conduction delay at the atrioventricular junction (AVJ), this study aims to investigate whether ...
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    15. 1-15 of 335 1 2 3 4 ... 21 22 23 »
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  2. About Case Western Reserve University

    Case Western Reserve University

    Case Western Reserve University. Case Western Reserve University is a private research university located in Cleveland, Ohio, United States, with some residence halls on the south end of campus located in Cleveland Heights. Biophotonics Imaging Laboratory at Case Western Reserve University.   Here at the BIL our researchers focus on the development of optical imaging technologies with focus on the development of solutions to specific clinical or research applications. Our primary tool of optical imaging is optical coherence tomography (OCT).