1. Carsten Framme

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    1. Mentioned In 13 Articles

    2. Optical coherence tomography angiography analysis of macular flow density in glaucoma

      Optical coherence tomography angiography analysis of macular flow density in glaucoma
      Purpose Modifications in ocular blood flow may play a significant role in glaucoma development. Optical coherence tomography angiography (OCT‐A) is based on the detection and analysis of the reflection behaviour of motion in a static environment and therefore is able to quantify the retinal flow density. We used this new technology to examine the density of the active flow vasculature in the macular area in glaucoma patients compared to ...
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      Mentions: Carsten Framme
    3. The short-term effects of aflibercept on the size of choroidal neovascularization lesion in treatment-resistant neovascular age-related macular degeneration as determined by spectral-domain optical coherence tomography

      The short-term effects of aflibercept on the size of choroidal neovascularization lesion in treatment-resistant neovascular age-related macular degeneration as determined by spectral-domain optical coherence tomography
      Background and Objectives To evaluate the changes in the size of choroidal neovascularization (CNV) lesion using spectral domain-optical coherence tomography (SD-OCT) in patients with treatment-resistant neovascular age-related macular degeneration (AMD) who were switched from ranibizumab to aflibercept. Materials and Methods In this prospective case-series, 33 eyes of 30 patients with treatment-resistant neovascular AMD were included. Treatment-resistant neovascular AMD was defined as choriodal neovascularization secondary to AMD determined by subretinal fluid ...
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    4. Time-Resolved Ultra–High Resolution Optical Coherence Tomography for Real-Time Monitoring of Selective Retina Therapy

      Time-Resolved Ultra–High Resolution Optical Coherence Tomography for Real-Time Monitoring of Selective Retina Therapy
      Purpose : Selective retina therapy (SRT) is a novel treatment for retinal pathologies, solely targeting the RPE. During SRT, the detection of an immediate tissue reaction is challenging, as tissue effects remain limited to intracellular RPE photodisruption. Time-resolved ultra-high axial resolution optical coherence tomography (OCT) is thus evaluated for the monitoring of dynamic optical changes at and around the RPE during SRT. Methods : An experimental OCT system with an ultra-high axial ...
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    5. Retinal Layer Measurements After Successful Macula-off Retinal Detachment Repair using OCT

      Retinal Layer Measurements After Successful Macula-off Retinal Detachment Repair using OCT
      Purpose: Optical coherence tomography (OCT) was used to analyze the thickness of various retinal layers of patients following successful macula-off retinal detachment (RD) repair. Methods: OCT scans of patients after successful macula-off RD repair were re-analyzed with a sub-segmentation algorithm to measure various retinal layers. Regression analysis was performed to correlate time after surgery with changes in layer thickness. In addition, patients were divided in two groups. Group 1 had ...
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    6. Behaviour of SD-OCT detected hyperreflective foci in the retina of Anti-VEGF treated patients with Diabetic Macular Edema

      Behaviour of SD-OCT detected hyperreflective foci in the retina of Anti-VEGF treated patients with Diabetic Macular Edema
      Purpose:Hyperreflective foci (HF) are observable within the neurosensory retina in diabetic macular edema (DME) using spectral domain optical coherence tomography (SD-OCT). The HF behaviour was evaluated during Anti-VEGF therapy in DME. Methods: Fifty-one patients (mean age: 67 years) underwent SD-OCT (Heidelberg engineering, Germany) before and one month after one Anti-VEGF injection (Ranibizumab: n=30; Bevacizumab: n=21). The amount of HFs were semi-quantitatively counted, assigned to 3 groups (A ...
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    7. Small Dense Particles in the Retina Observable by Spectral-Domain Optical Coherence Tomography in Age-Related Macular Degeneration

      Small Dense Particles in the Retina Observable by Spectral-Domain Optical Coherence Tomography in Age-Related Macular Degeneration
      Purpose. To observe detailed changes in neurosensory retinal structure after anti-VEGF upload in age-related macular degeneration (AMD), by using spectral domain optical coherence tomography (SD-OCT). Methods. The retinal structure was observed by using SD-OCT in 61 patients, before and 1 month after the third ranibizumab injection (upload phase). The main focus of attention was a subjective determination of the amount and behavior of the numerous small, dense particles (SDPs) frequently ...
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    8. Small dense particles within the neurosensory retinal layers observable by Spectral Domain Optical Coherence Tomography in Age-related macular Degeneration

      Small dense particles within the neurosensory retinal layers observable by Spectral Domain Optical Coherence Tomography in Age-related macular Degeneration
      ...rn, Bern, Switzerland^ ^3Department of Ophthalmology, University of Bern, Bern, Switzerland ^ Correspondence: Carsten Framme, Email: carsten.framme{at}insel.ch Abstract Purpose: To observe detailed changes of neurosensor...
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    9. Effects on Choroidal Neovascularization after Anti-VEGF Upload Using Intravitreal Ranibizumab, as Determined by Spectral Domain-Optical Coherence Tomography

      ...nti-VEGF Upload Using Intravitreal Ranibizumab, as Determined by Spectral Domain-Optical Coherence Tomography Carsten Framme,^1^,2 Georgios Panagakis,^1 and Reginald Birngruber^3 ^From the ^1University Eye Hospital, Rege...
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    10. Structural changes of the retina after conventional laser photocoagulation and selective retina treatment (SRT) in spectral domain OCT.

      Background: Spectral domain optical coherence tomography (SD-OCT) in patients can deliver retinal cross-sectional images with high resolution. This may allow the evaluation of the extent of damage to the retinal pigment epithelium (RPE) and the neurosensory retina after laser treatment. This article aims to investigate the value of SD-OCT in comparing laser lesions produced by conventional laser photocoagulation and selective retina treatment (SRT). Material and Methods: In a retrospective study ...
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    11. Effects on Choroidal Neovascularizations after Anti-VEGF Upload Using Intravitreal Ranibizumab as Determined by Spectral Domain Optical Coherence Tomography

      ...Regensburg, Germany^ ^3Institute of Biomedical Optics, University Luebeck, Luebeck, Germany ^ Correspondence: Carsten Framme, Email: carsten.framme{at}insel.ch Abstract Purpose: To image CNV structure before and after an...
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    12. Retreatment of full-thickness macular hole: predictive value of optical coherence tomography

      Aim: To determine whether the efficacy of re-operation for idiopathic full-thickness macular hole (FTMH) remaining open after initial surgery with internal limiting membrane (ILM) peeling is correlated with macular hole configuration as determined by optical coherence tomography (OCT), macular hole size, macular hole duration before the first operation, or type of tamponade (gas or silicone oil). Methods: A retrospective consecutive interventional case series of 28 patients (28 eyes) with a ...
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      Mentions: Carsten Framme
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  2. About Carsten Framme

    Carsten Framme is and Opthalmologist with the University of Regensburg in Germany.