1. Caroline Boudoux

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    1. Mentioned In 22 Articles

    2. Utility of Optical Coherence Tomography for Guiding Laser Therapy Among Patients With Recurrent Respiratory Papillomatosis

      Utility of Optical Coherence Tomography for Guiding Laser Therapy Among Patients With Recurrent Respiratory Papillomatosis
      Importance Recurrent respiratory papillomatosis (RRP) is a viral-induced disease caused by human papillomavirus and the second leading cause of dysphonia in children; however, neither a cure nor a definitive surgical treatment is currently available for RRP. Although laser therapy is often used in the treatment of RRP, the lack of real-time laser-tissue interaction feedback undermines the ability of physicians to provide treatments with low morbidity. Therefore, an intraoperative tool to ...
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    3. Biophotonics and Imaging Graduate Summer School (BIGSS`18) AUGUST 28 - SEPTEMBER 1, 2018 at The Burren and NUI Galway

      Biophotonics and Imaging Graduate Summer School (BIGSS`18) AUGUST 28 - SEPTEMBER 1, 2018  at The Burren and NUI Galway
      ... and linear and nonlinear properties of plasmonic nanoparticles including their electronically resonant FWM. Caroline Boudoux (Montreal) – Endoscopy Total internal reflection to fibre optics, single- and multi-mode, s...
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    4. Radiometric model for coaxial single- and multimode optical emission from double-clad fiber

      Radiometric model for coaxial single- and multimode optical emission from double-clad fiber
      Double-clad fibers (DCFs) are versatile waveguides supporting a single-mode core surrounded by a multimode inner cladding. DCFs are increasingly used for multimodal biomedical applications, such as imaging or therapy, for which the core is typically used for coherent illumination and the inner cladding, to support a concurrent modality. Proper optimization is, however, critical to ensure high optical performance and requires accurate modeling of coaxial single- and multimode output beams. In ...
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    5. Simultaneous multimodal ophthalmic imaging using swept-source spectrally encoded scanning laser ophthalmoscopy and optical coherence tomography

      Simultaneous multimodal ophthalmic imaging using swept-source spectrally encoded scanning laser ophthalmoscopy and optical coherence tomography
      Scanning laser ophthalmoscopy (SLO) benefits diagnostic imaging and therapeutic guidance by allowing for high-speeden faceimaging of retinal structures. When combined with optical coherence tomography (OCT), SLO enables real-time aiming and retinal tracking and provides complementary information for post-acquisition volumetric co-registration, bulk motion compensation, and averaging. However, multimodality SLO-OCT systems generally require dedicated light sources, scanners, relay optics, detectors, and additional digitization and synchronization electronics, which increase system complexity. Here, we ...
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    6. Combined optical coherence tomography and hyperspectral imaging using a double-clad fiber coupler

      Combined optical coherence tomography and hyperspectral imaging using a double-clad fiber coupler
      This work demonstrates the combination of optical coherence tomography (OCT) and hyperspectral imaging (HSI) using a double-clad optical fiber coupler. The single-mode core of the fiber is used for OCT imaging, while the inner cladding of the double-clad fiber provides an efficient way to capture the reflectance spectrum of the sample. The combination of both methods enables three-dimensional acquisition of the sample morphology with OCT, enhanced with complementary molecular information ...
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    7. Collagen Content Limits Optical Coherence Tomography Image Depth in Porcine Vocal Fold Tissue

      Collagen Content Limits Optical Coherence Tomography Image Depth in Porcine Vocal Fold Tissue
      Objective Vocal fold scarring, a condition defined by increased collagen content, is challenging to treat without a method of noninvasively assessing vocal fold structure in vivo. The goal of this study was to observe the effects of vocal fold collagen content on optical coherence tomography imaging to develop a quantifiable marker of disease. Study Design Excised specimen study. Setting Massachusetts Eye and Ear Infirmary. Subjects and Methods Porcine vocal folds ...
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    8. Tri-modal microscope for head and neck tissue identification

      Tri-modal microscope for head and neck tissue identification
      A novel tri-modal microscope combining optical coherence tomography (OCT), spectrally encoded confocal microscopy (SECM) and fluorescence imaging is presented. This system aims at providing a tool for rapid identification of head and neck tissues during thyroid surgery. The development of a dual-wavelength polygon-based swept laser allows for synchronized, co-registered and simultaneous imaging with all three modalities. Further ameliorations towards miniaturization include a custom lens for optimal compromise between orthogonal imaging ...
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    9. Combined optical coherence tomography and hyper-spectral imaging using a double clad fiber coupler

      Combined optical coherence tomography and hyper-spectral imaging using a double clad fiber coupler
      This proceedings shows the combination of Optical Coherence Tomography (OCT) and Hyper-Spectral Imaging (HSI) using a double-clad optical fiber. The single mode core of the fiber is used to transmit OCT signals, while the cladding, with its large collection area, provides an efficient way to capture the reflectance spectrum of the sample. The combination of both methods enables three-dimensional acquisition of sample morphology with OCT, enhanced by the molecular information ...
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    10. Towards in vivo laser coagulation and concurrent optical coherence tomography through double-clad fiber devices

      Towards in vivo laser coagulation and concurrent optical coherence tomography through double-clad fiber devices
      There is a strong clinical need for an optical coherence tomography (OCT) system capable of delivering concurrent coagulation light enabling image-guided dynamic laser marking for targeted collection of biopsies, as opposed to a random sampling, to reduce false-negative findings. Here, we present a system based on double-clad fiber (DCF) capable of delivering pulsed laser light through the inner cladding while performing OCT through the core. A previously clinically validated commercial ...
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    11. Multimodal ophthalmic imaging using swept source spectrally encoded scanning laser ophthalmoscopy and optical coherence tomography

      Multimodal ophthalmic imaging using swept source spectrally encoded scanning laser ophthalmoscopy and optical coherence tomography
      Scanning laser ophthalmoscopy (SLO) and optical coherence tomography (OCT) benefit clinical diagnostic imaging in ophthalmology by enabling in vivo noninvasive en face and volumetric visualization of retinal structures, respectively. Spectrally encoding methods enable confocal imaging through fiber optics and reduces system complexity. Previous applications in ophthalmic imaging include spectrally encoded confocal scanning laser ophthalmoscopy (SECSLO) and a combined SECSLO-OCT system for image guidance, tracking, and registration. However, spectrally encoded imaging ...
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    12. Intraoperative imaging of pediatric vocal fold lesions using optical coherence tomography

      Intraoperative imaging of pediatric vocal fold lesions using optical coherence tomography
      Optical coherence tomography (OCT) has been previously identified as a promising tool for exploring laryngeal pathologies in adults. Here, we present an OCT handheld probe dedicated to imaging the unique geometry involved in pediatric laryngoscopy. A vertical cavity surface emitting laser-based wavelength-swept OCT system operating at 60 frames per second was coupled to the probe to acquire three-dimensional (3-D) volumes in vivo . In order to evaluate the performance of the ...
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    13. Toward an automated method for optical coherence tomography characterization

      Toward an automated method for optical coherence tomography characterization
      With the increasing use of optical coherence tomography (OCT) in biomedical applications, robust yet simple methods for calibrating and benchmarking a system are needed. We present here a procedure based on a calibration object complemented with an algorithm that analyzes three-dimensional OCT datasets to retrieve key characteristics of an OCT system. The calibration object combines state-of-the-art tissue phantom material with a diamond-turned aluminum multisegment mirror. This method is capable of ...
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    14. Using attenuation coefficients from optical coherence tomography as markers of vocal fold maturation

      Using attenuation coefficients from optical coherence tomography as markers of vocal fold maturation
      Objectives/Hypothesis Optical coherence tomography (OCT) is a promising technology to noninvasively assess vocal fold microanatomy. The goal of this study was to develop a methodology using OCT to identify quantifiable markers of vocal fold development. Study Design In vivo study. Methods A two-step process was developed to reproducibly image the midmembranous vocal fold edge of 10 patients younger than 2 years and 10 patients between 11 and 16 years ...
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    15. Feature Of The Week 5/10/2015: Laser Tissue Coagulation and Concurrent Optical Coherence Tomography Through a Double-Clad Fiber Coupler

      Feature Of The Week 5/10/2015: Laser Tissue Coagulation and Concurrent Optical Coherence Tomography Through a Double-Clad Fiber Coupler
      ...te from Polytechnique Montreal. This work is the result of a collaboration between researchers from Professor Caroline Boudoux’s team from Polytechnique Montréal (Canada) and Professor Brett E. Bouma’s team at the Wellma...
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    16. Molecular imaging needles: dual-modality optical coherence tomography and fluorescence imaging of labeled antibodies deep in tissue

      Molecular imaging needles: dual-modality optical coherence tomography and fluorescence imaging of labeled antibodies deep in tissue
      ...lie Madore,^2 Rodney W. Kirk,^1 Anne S. Kramer,^3 George C. Yeoh,^3 Nicolas Godbout,^2 David D. Sampson,^1,^4 Caroline Boudoux,^2 and Robert A. McLaughlin^1 ^1Optical + Biomedical Engineering Laboratory, School of Elec...
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    17. 1-15 of 22 1 2 »
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  2. About Caroline Boudoux

    Caroline Boudoux

    Caroline Boudoux is an Associate Professor and Director of the Laboratory of Optical Diagnoses and Imaging  Department of Engineering Physics, École Polytechnique de Montréal; Researcher at Sainte-Justine Hospital Research Center, Montréal's Mother and Child Hospital;  Co-president and co-founder, Castor Optics; and Lecturer at Harvard Medical School.