1. Carnegie Mellon University

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    1. Mentioned In 24 Articles

    2. Enhanced spectral-domain optical coherence tomography (SD-OCT) using in situ ultrasonic virtual tunable optical waveguides

      Enhanced spectral-domain optical coherence tomography (SD-OCT) using in situ ultrasonic virtual tunable optical waveguides
      A conventional optical lens can enhance lateral resolution in optical coherence tomography (OCT) by focusing the input light onto the sample. However, the typical Gaussian beam profile of such a lens will impose a tradeoff between the depth of focus (DOF) and the lateral resolution. The lateral resolution is often compromised to achieve a mm-scale DOF. We have experimentally shown that using a cascade system of an ultrasonic virtual tunable ...
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    3. In situ volumetric imaging and analysis of FRESH 3D bioprinted constructs using optical coherence tomography

      In situ volumetric imaging and analysis of FRESH 3D bioprinted constructs using optical coherence tomography
      As 3D bioprinting has grown as a fabrication technology, so too has the need for improved analytical methods to characterize engineered constructs. This is especially challenging for engineered tissues composed of hydrogels and cells, as these materials readily deform when trying to assess print fidelity and other properties non-destructively. Establishing that the 3D architecture of the bioprinted construct matches its intended anatomic design is critical given the importance of structure-function ...
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    4. In Situ Volumetric Imaging and Analysis of FRESH 3D Bioprinted Constructs Using Optical Coherence Tomography

      In Situ Volumetric Imaging and Analysis of FRESH 3D Bioprinted Constructs Using Optical Coherence Tomography
      As 3D bioprinting has grown as a fabrication technology, so too has the need for improved analytical methods to characterize these engineered constructs. This is especially challenging for soft tissues composed of hydrogels and cells as these materials readily deform, posing a barrier when trying to assess print fidelity and other properties non-destructively. Indeed, given the importance of structure-function relationships in most tissue types, establishing that the 3D architecture of ...
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    5. The Optical Coherence Tomography Microsurgical Augmented Reality System (OCT-MARS): A Novel Device for Microsurgeries (Thesis)

      The Optical Coherence Tomography Microsurgical Augmented Reality System (OCT-MARS): A Novel Device for Microsurgeries (Thesis)
      This thesis describes the development and testing of the Optical Coherence Tomography Microsurgical Augmented Reality System (OCT-MARS). This system allows surgeons to view real-time medical image data as an in situ overlay within the surgical field. There are a number of clinical applications for which real time, in situ visualization of otherwise transparent structures of the eye would be beneficial to surgeons. The primary motivating application for this project is ...
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    6. Characterization of zebrafish larvae suction feeding flow using μPIV and optical coherence tomography

      Characterization of zebrafish larvae suction feeding flow using μPIV and optical coherence tomography
      The hydrodynamics of suction feeding is critical for the survival of fish larvae; failure to capture food during the onset of autonomous feeding can rapidly lead to starvation and mortality. Fluid mechanics experiments that investigate the suction feeding of suspended particles are limited to adult fishes, which operate at large Reynolds numbers. This manuscript presents the first literature results in which the external velocity fields generated during suction feeding of ...
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    7. Handheld Micromanipulator for Robot-Assisted Microsurgery (Thesis)

      Handheld Micromanipulator for Robot-Assisted Microsurgery (Thesis)
      Robot-assisted surgery has been increasingly adopted in a wide variety of surgical applications because it offers fine manipulation with high precision and dexterity. Despite the commercial success of robotic platforms, practical use in microsurgery is still challenging due to a considerable level of accuracy required at sub-millimeter scales. Limited visualization and constrained accessibility also hinder operation under operating microscopes. Furthermore, lack of tactile feedback may lead to substantial and even ...
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    8. University of Pittsburgh Receives NIH Grant for Novel Glaucoma Diagnostics for Structure and Function

      University of Pittsburgh Receives NIH Grant for Novel Glaucoma Diagnostics for Structure and Function
      ...ort personnel, from the University of Pittsburgh, Tufts University, Massachusetts Institute of Technology and Carnegie Mellon University. We have brought excellent investigators from disparate fields to bring new insight...
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    9. Joel S. Schuman, M.D., Part of Team Receiving António Champalimaud Vision Award

      Joel S. Schuman, M.D., Part of Team Receiving António Champalimaud Vision Award
      ... for Regenerative Medicine at Pitt/UPMC, the Center for the Neural Basis of Cognition jointly run by Pitt and Carnegie Mellon University, and in the Department of Bioengineering at Pitt’s Swanson School of Engineering, a...
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    10. Optical coherence tomography scanning with a handheld vitreoretinal micromanipulator

      Optical coherence tomography scanning with a handheld vitreoretinal micromanipulator
      An active handheld micromanipulator has been developed that is capable of automated intraocular acquisition of B-mode and C-mode optical coherence tomography scans that are up to 4 mm wide. The manipulator is a handheld Gough-Stewart platform actuated by ultrasonic linear motors. The manipulator has been equipped with a Fourier-domain common-path intraocular OCT probe that fits within a 25-gauge needle. The paper describes the systems and techniques involved, and presents preliminary ...
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    11. 1-15 of 24 1 2 »
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  2. About Carnegie Mellon University

    Carnegie Mellon University

    Carnegie Mellon University is a global research university with more than 11,000 students, 86,500 alumni, and 4,000 faculty and staff. Recognized for its world-class arts and technology programs, collaboration across disciplines and innovative leadership in education, CMU is consistently a top-ranked university