1. Carl Zeiss Meditec

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    1. Mentioned In 1324 Articles

    2. Optical Coherence Tomography System

      Optical Coherence Tomography System

      An OCT system comprises an OCT scan module for retinal scanning and an add-on anterior segment scanning module which includes at least one anterior segment scan lens (11) and an add-on fixation target (15) which is used to maintain the viewing direction of the eye (6) under investigation while achieving anterior segment scanning.

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    3. Comparison between the measurements of different parameters obtained from optic nerve head analysis by using Heidelberg retinal tomography (HRT3) and Optical coherence tomography (Stratus OCT)

      Comparison between the measurements of different parameters obtained from optic nerve head analysis by using Heidelberg retinal tomography (HRT3) and Optical coherence tomography (Stratus OCT)

      Purpose: A cross-sectional prospective nonrandomized study was undertaken to find out whether Heidelberg retinal tomography (HRT3) and Optical coherence tomography (Stratus OCT) could be used interchangeably for the measurement of different parameters of optic nerve head in clinical practice. Materials and Methods: Measurements of disc area, cup area, rim area and cup-disc area ratio were obtained with the HRT3 and Stratus OCT printouts in 18 patients aged 20 to 70 years. True agreements between methods in measuring disc area, cup area, rim area and cup-disc area ratio were assessed using Bland-Altman statistical analysis. Eighteen patients with a mean age of ...

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    4. Comparison of penetration depth in choroidal imaging using swept source vs spectral domain optical coherence tomography

      Comparison of penetration depth in choroidal imaging using swept source vs spectral domain optical coherence tomography

      Purpose To compare signal penetration depth and deep structure-visualization of swept source (SS) and spectral domain (SD)-optical coherence tomography (OCT) with and without enhanced depth imaging (EDI) and B-scan averaging modes. Methods Volume scans were obtained from 20 eyes of healthy volunteers by DRI OCT-1, Spectralis using EDI and B-scan averaging, and Cirrus HD-OCT. The signal penetration depth was measured as the distance between the retinal pigment epithelium and the deepest visible anatomical structure at the foveal center. Visibility and contrast of the choroidoscleral junction and of vascular details within the choroid were assessed across the entire volume using ...

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    5. Effects of Axial Length and Age on Circumpapillary Retinal Nerve Fiber Layer and Inner Macular Parameters Measured by 3 Types of SD-OCT Instruments

      Effects of Axial Length and Age on Circumpapillary Retinal Nerve Fiber Layer and Inner Macular Parameters Measured by 3 Types of SD-OCT Instruments

      Purposes: To evaluate the effects of axial length and age on the circumpapillary retinal nerve fiber layer (cpRNFL) and the inner macular parameters measured using 3 spectral-domain optical coherence tomography (OCT) instruments. Methods: A total of 102 normal eyes (1 eye per subject) were imaged using Cirrus, RTVue, and 3D-OCT. The cpRNFL and the macular retinal nerve fiber layer (mRNFL), the ganglion cell layer+inner plexiform layer (GCLIPL), and the mRNFL+GCLIPL ganglion cell complex, GCC thicknesses were analyzed. The correlations between these values and the axial length or age were evaluated using a partial correlation analysis. These correlations were ...

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    6. Clinical Use of an Optical Coherence Tomography Linear Discriminant Function for Differentiating Glaucoma From Normal Eyes

      Clinical Use of an Optical Coherence Tomography Linear Discriminant Function for Differentiating Glaucoma From Normal Eyes

      Purpose: To determine and validate the diagnostic ability of a linear discriminant function (LDF) based on retinal nerve fiber layer (RNFL) and ganglion cell-inner plexiform layer (GCIPL) thickness obtained using high-definition optical coherence tomography (Cirrus HD-OCT) for discriminating between healthy controls and early glaucoma subjects. Methods: We prospectively selected 214 healthy controls and 152 glaucoma subjects (teaching set) and another independent sample of 86 healthy controls and 71 glaucoma subjects (validating set). Two scans, including 1 macular and 1 peripapillary RNFL scan, were obtained. After calculating the LDF in the teaching set using the binary logistic regression analysis, receiver operating ...

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    7. Angle closure glaucoma detection using fractal dimension index on SS-OCT images

      Angle closure glaucoma detection using fractal dimension index on SS-OCT images

      Optical coherence tomography (OCT) is a high resolution, rapid and non-invasive screening tool for angle closure glaucoma. In this paper, we propose a new strategy for automatic and landmark invariant quantification of the anterior chamber angle of the eye using swept source optical coherence tomography (SS-OCT) images. Seven hundred and eight swept source optical coherence tomography SS-OCT images from 148 patients with average age of (59.48 ± 8.97) were analyzed in this study. The angle structure is measured by fractal dimension (FD) analysis to quantify the complexity or changes of angle recess. We evaluated the FD index with biometric ...

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    8. Optical Coherence Tomography Measurements of Choroidal Thickness in Healthy Eyes: Correlation With Age and Axial Length

      Optical Coherence Tomography Measurements of Choroidal Thickness in Healthy Eyes: Correlation With Age and Axial Length
      ... from Carl Zeiss Meditec. Dr. Gregori received research support from and co-owns a patent that is licensed to Carl Zeiss Meditec. Dr. Rosenfeld has received research support from Carl Zeiss Meditec, Macular Vision Resear...
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    9. Quantitative comparison of macular segmentation performance using identical retinal regions across multiple spectral-domain optical coherence tomography instruments

      Quantitative comparison of macular segmentation performance using identical retinal regions across multiple spectral-domain optical coherence tomography instruments

      Purpose Comparison of optical coherence tomography (OCT) segmentation performance regarding technical accuracy and clinical relevance. Methods 29 eyes were imaged prospectively with Spectralis (Sp), Cirrus (Ci), 3D-OCT 2000 (3D) and RS-3000 (RS) OCTs. Raw data were evaluated in validated custom software. A 1 mm diameter subfield, centred on the fovea, was investigated to compare identical regions for each case. Segmentation errors were corrected on each B-scan enclosed in this subfield. Proportions of wrongly segmented A-scans were noted for inner and outer retinal boundaries. Centre point thickness (CPT) and central macular thickness (CMT) were compared before and after correction. Results Segmentation ...

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    10. Test-Retest Variability of Retinal Nerve Fiber Layer Thickness and Macular Ganglion Cell-Inner Plexiform Layer Thickness Measurements Using Spectral-Domain Optical Coherence Tomography

      Test-Retest Variability of Retinal Nerve Fiber Layer Thickness and Macular Ganglion Cell-Inner Plexiform Layer Thickness Measurements Using Spectral-Domain Optical Coherence Tomography

      Purpose: To evaluate the test-retest variability of spectral-domain optical coherence tomography (OCT) in measurement of retinal nerve fiber layer (RNFL) thickness and macular ganglion cell-inner plexiform layer (GCIPL) thickness. Methods: A total of 65 eyes of healthy subjects were enrolled in this observational cross-sectional study. RNFL thickness and GCIPL thickness were measured using the repeat scan optic cube and macular cube protocol using Cirrus HD-OCT (software version 6.0). A single operator obtained 3 measurements during 1 session to determine test-retest variability. Intrasession repeatability was defined by intraclass correlation, limits of agreement, and coefficient of variation. Results: The mean age ...

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    11. Comparison of event-based analysis of glaucoma progression assessed subjectively on visual fields and retinal nerve fibre layer attenuation measured by optical coherence tomography

      Comparison of event-based analysis of glaucoma progression assessed subjectively on visual fields and retinal nerve fibre layer attenuation measured by optical coherence tomography
      ... fiber layer thickness in glaucoma. Arch Ophthalmol 123(4):464–470 Stratus OCT Model 3000 User Manual (2003) Carl Zeiss Meditec, Dublin Mills RP, Budenz DL, Lee PP, Noecker RJ, Walt JG, Siegartel LR et al (2006) Catego...
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    12. Effects of Misalignments in the Retinal Nerve Fiber Layer Thickness Measurements with Spectral Domain Optical Coherence Tomography

      Effects of Misalignments in the Retinal Nerve Fiber Layer Thickness Measurements with Spectral Domain Optical Coherence Tomography

      Purpose . To investigate misalignments (MAs) on retinal nerve fiber layer thickness (RNFLT) measurements obtained with SD-OCT. Methods . This was a retrospective, observational, cross-sectional study. Twenty-seven healthy and 29 glaucomatous eyes of 56 individuals with one normal exam and another showing MA were included. MAs were defined as an improper alignment of vertical vessels in the en face image. MAs were classified in complete MA (CMA) and partial MA (PMA), according to their site: 1 (superior, outside the measurement ring (MR)), 2 (superior, within MR), 3 (inferior, within MR), and 4 (inferior, outside MR). We compared RNFLT measurements of aligned versus ...

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    13. High-Speed Ultrahigh-Resolution OCT of Bruch's Membrane in Membranoproliferative Glomerulonephritis Type 2

      High-Speed Ultrahigh-Resolution OCT of Bruch's Membrane in Membranoproliferative Glomerulonephritis Type 2
      ... to Carl Zeiss Meditec and Optovue and has stock options in Optovue. Dr. Duker receives research support from Carl Zeiss Meditec and Optovue. The remaining authors have no financial or proprietary interest in the materia...
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    14. Intereye Comparison of Cirrus OCT in Early Glaucoma Diagnosis and Detecting Photographic Retinal Nerve Fiber Layer Abnormalities

      Intereye Comparison of Cirrus OCT in Early Glaucoma Diagnosis and Detecting Photographic Retinal Nerve Fiber Layer Abnormalities

      Purpose: To compare the ability of various maps constructed using Cirrus optical coherence tomography (OCT), including the "intereye comparison" derived from the temporal-superior-inferior-nasal-temporal (TSNIT) map, in terms of glaucoma diagnosis and detection of RNFL defects identified in red-free fundus photographs. Methods: This cross-sectional study was conducted on a total of 131 open-angle glaucoma patients with early-stage visual field defects (mean deviation ≤ -6.0 dB) and 56 normal controls. Intereye differences were identified on TSNIT maps constructed by comparing the RNFL thickness curves of both eyes of individual patients and a separation of the RNFL thickness curves of either eye (by ...

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  2. About Carl Zeiss Meditec

    Carl Zeiss Meditec

    Carl Zeiss Meditec.  Ophthalmology Systems.  Carl Zeiss Meditec is an integrated medical technology company with two main areas of business activity.  In the field of ophthalmology we offer complete solutions for treating the four main eye ailments: vision defects (refraction), cataract, glaucoma and retinal disorders. Our products support doctors and patients to diagnose and treat these ailments efficiently and precisely, thus giving both of them clear benefits, not least by offering them a comprehensive disease management solution. The acquisition of Carl Zeiss Surgical has strengthened our leading market and competitive position for devices and systems in ophthalmic surgery.  Furthermore, we have secured an outstanding starting position in the growth market of neuro/ENT surgery. As the world‘s leading provider of surgical microscopes and visualisation solutions for these treatments, we will further expand our footprint in this area through organic growth and strategic expansion into adjacent market segments. In doing so, we want to develop into a solution provider in this area as well.  Carl Zeiss Meditec's medical technology portfolio is rounded off by innovative and promising future technologies such as intraoperative radiation therapy, which allows the targeted treatment of breast cancer and brain cancer during the operation stage itself.

  3. Quotes about Carl Zeiss Meditec

    1. I have come to rely on the Carl Zeiss Meditec brand for consistent and reliable technologies that are at the forefront of innovation and patient care.
      Ike K. Ahmed in Carl Zeiss Meditec Introduces New Suite of Ophthalmic Innovations
    2. Mr Taylor has been instrumental in making Meditec one of the leading companies in the field of ophthalmology in the past few years. My sincere thanks are due to him for his effort and dedication. I am pleased that Mr Taylor will continue to support us in the role of independent consultant and that we will be able to draw on his experience in future. Furthermore, I am convinced that we are ideally set with our current team to accelerate the proposed realisation of growth potential of Carl Zeiss Meditec.
      Michael Kaschke in Carl Zeiss Meditec reorganises management of its strategic business units
    3. Carl Zeiss Meditec received the highest overall Frost & Sullivan Competitive Metrics Score in the recently completed Strategic Analysis of Optical Imaging Technologies in U.S. Clinical Diagnostics Markets.
      In Frost & Sullivan Lauds Carl Zeiss Meditec for Dominating the OCT Market for Ophthalmic Applications