1. Carl Zeiss Meditec

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    1. Mentioned In 1281 Articles

    2. A comprehensive model for correcting RNFL readings of varying signal strengths in CIRRUS Optical Coherence Tomography (OCT)

      A comprehensive model for correcting RNFL readings of varying signal strengths in CIRRUS Optical Coherence Tomography (OCT)

      Purpose. Develop a model for the CIRRUSTM HD-OCT that allows for the comparison of retinal nerve fiber layer (RNFL) thickness measurements with dissimilar signal strengths (SS) and accounts for test-re-test variability. Methods. RNFLs were obtained in normals using the CIRRUSTM optic disc cube 200x200 protocol during a single encounter. Five RNFL scans were obtained with a SS of 9-10. Diffusion lens filters were used to degrade SS to obtain five scans at each SS group of 7-8, 5-6, and 3-4. The relationship between average RNFL thickness and SS was established and an equation was developed to allow for adjustment of ...

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    3. Effect of Angle of Incidence on Anterior Chamber Angle Metrics From Optical Coherence Tomography

      Effect of Angle of Incidence on Anterior Chamber Angle Metrics From Optical Coherence Tomography

      Purpose: To evaluate the local variability of anterior chamber angle (ACA) metrics obtained by time domain (TD) and spectral domain (SD) optical coherence tomography (OCT). Materials and Methods: Anterior-segment OCT imaging was performed on 30 normal eyes using Visante TD-OCT and 40 normal eyes using Cirrus SD-OCT. For Visante OCT, a single 16-mm line scan of the inferior angle with 3 slightly different rotations of 265, 270, and 275 degrees was performed. For Cirrus OCT, a 5-line raster of the inferior angle was performed, centering the third scan line at the 6 o'clock position, with 0.25 mm between ...

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    4. Correlation and Agreement Between Cirrus HD-OCT "RNFL Thickness Map" and Scan Circle Retinal Nerve Fiber Layer Thickness Measurements

      Correlation and Agreement Between Cirrus HD-OCT "RNFL Thickness Map" and Scan Circle Retinal Nerve Fiber Layer Thickness Measurements

      Purpose: To evaluate the correlation and agreement between optical coherence tomography (Cirrus HD-OCT) retinal nerve fiber layer (RNFL) thickness map and scan circle RNFL thickness measurements. Methods: ImageJ and custom Perl scripts were used to derive RNFL thickness measurements from RNFL thickness maps of optic disc scans of healthy and glaucomatous eyes. Average, quadrant, and clock-hour RNFL thickness of the map, and RNFL thickness of the areas inside/outside the scan circle were obtained. Correlation and agreement between RNFL thickness map and scan circle RNFL thickness measurements were evaluated using R2 and Bland-Altman plots, respectively. Results: A total of 104 ...

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    5. Reproducibility of Anterior Segment Angle Metrics Measurements Derived From Cirrus Spectral Domain Optical Coherence Tomography

      Reproducibility of Anterior Segment Angle Metrics Measurements Derived From Cirrus Spectral Domain Optical Coherence Tomography

      Purpose: To investigate the reproducibility of anterior segment angle (ACA) metrics measurements in normal subjects on Cirrus spectral domain optical coherence tomography (SD-OCT). Methods: 40 eyes from 20 healthy, normal subjects underwent anterior segment imaging using a Cirrus SD-OCT. For each eye, 2 acquisitions of 5-line raster scans were performed perpendicularly on the inferior (270 degrees) angle. The Schwalbe's line-angle opening distance (SL-AOD) and Schwalbe's line-trabecular-iris space area (SL-TISA) measurements were performed by masked certified reading center graders using customized grading software. Intra-acquisition, intergrader, and intragrader reproducibility of SL-AOD and SL-TISA measurements were evaluated by intraclass correlation coefficients ...

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    6. Difference in Subfoveal Choroidal Thickness between Two Spectral-Domain Optical Coherence Tomography Systems

      Difference in Subfoveal Choroidal Thickness between Two Spectral-Domain Optical Coherence Tomography Systems

      Purpose To determine the difference in subfoveal choroidal thickness between two spectral-domain optical coherence tomography (SD-OCT) systems in normal eyes and eyes with retinal diseases. Methods Thirty-three normal eyes and 49 eyes with retinal disease (13 eyes with diabetic retinopathy, 28 eyes with epiretinal membrane and eight eyes with macular hole) were enrolled in the study. Subfoveal choroidal thicknesses were measured by 3 observers using the enhanced depth imaging technique of Heidelberg Spectralis® and the high-definition five-line raster scan of Cirrus HD-OCT® using calipers within the program. Differences between the measured values were analyzed with a paired t -test in ...

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    7. Swept-Source OCT Angiography of the Retinal Vasculature Using Intensity Differentiation-based Optical Microangiography Algorithms

      Swept-Source OCT Angiography of the Retinal Vasculature Using Intensity Differentiation-based Optical Microangiography Algorithms

      To demonstrate the feasibility of using a 1,050-nm swept-source optical coherence tomography (SS-OCT) system to achieve noninvasive retinal vasculature imaging in human eyes. MATERIALS AND METHODS: Volumetric data sets were acquired using a 1-µm SS-OCT prototype that operated at a 100-kHz A-line rate. A scanning protocol designed to allow for motion contrast processing, referred to as OCT angiography or optical microangiography (OMAG), was used to scan an approximately 3 × 3–mm area in the central macular region of the retina within approximately 4.5 seconds. An intensity differentiation-based OMAG algorithm was used to extract three-dimensional retinal functional microvasculature ...

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    8. Repeatability of peripapillary retinal nerve fiber layer and inner retinal thickness among 2 spectral domain optical coherence tomography devices

      Repeatability of peripapillary retinal nerve fiber layer and inner retinal thickness among 2 spectral domain optical coherence tomography devices

      PURPOSE. To compare measurement of macular inner retina and peripapillary retinal nerve fiber layer (pRNFL) thickness using 2 spectral-domain optical coherence tomography (OCT) devices in glaucoma patients, patients with ocular hypertension, idiopathic and atypical Parkinson's disease and healthy controls. METHODS. One-hundred seventy-one eyes of 146 participants underwent successful pRNFL and macular scanning and automated measurement of ganglion cell layer + inner plexiform layer (GCL-IPL) using Cirrus® HD-OCT or retinal nerve fiber layer + ganglion cell layer + inner plexiform layer (RNFL-GCL-IPL) using RTVue-100®. Macular RNFL was added to the GCL-IPL thickness measured by Cirrus and was compared to the RNFL-GCL-IPL thickness of ...

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    9. In Vivo Three-Dimensional Characterization of the Healthy Human Lamina Cribrosa with Adaptive Optics Spectral-Domain Optical Coherence Tomography

      In Vivo Three-Dimensional Characterization of the Healthy Human Lamina Cribrosa with Adaptive Optics Spectral-Domain Optical Coherence Tomography

      Purpose: To characterize the in vivo 3D lamina cribrosa (LC) microarchitecture of healthy eyes using adaptive optics spectral-domain optical coherence tomography (AO-SDOCT). Methods: One randomly selected eye from each of 18 healthy subjects was scanned with Cirrus HD-OCT and AO-SDOCT centered on the optic nerve head. LC microarchitecture, imaged by the later device, was semi-automatically segmented and quantified for connective tissue volume fraction (CTVF), beam thickness, pore diameter, pore area and pore aspect ratio. The LC was assessed in central and peripheral regions of equal areas, quadrants and with depth. A linear mixed-effects model weighted by the fraction of visible ...

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    10. Characterization of macular thickness changes in Leber's hereditary optic neuropathy by optical coherence tomography

      Characterization of macular thickness changes in Leber's hereditary optic neuropathy by optical coherence tomography

      Background To characterize macular thickness (MT) changes in Leber's hereditary optic neuropathy (LHON) patients by cirrus HD-optical coherence tomography (OCT), and to study the correlation between MT and best corrected visual acuity (BCVA). Methods Fifty-two eyes from 52 consecutive LHON patients and 14 eyes from 14 age- and sex-matched healthy controls were scanned by OCT. Affected eyes were classified into five groups according to disease duration (1st group: <=3 months; 2nd group: 3-6 months; 3rd group: 6-9 months; 4th group: 9-12 months; and 5th group: >12 months). MT was compared and analyzed. The correlation between BCVA and MT was ...

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    11. 1-15 of 1281 1 2 3 4 ... 84 85 86 »
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  2. About Carl Zeiss Meditec

    Carl Zeiss Meditec

    Carl Zeiss Meditec.  Ophthalmology Systems.  Carl Zeiss Meditec is an integrated medical technology company with two main areas of business activity.  In the field of ophthalmology we offer complete solutions for treating the four main eye ailments: vision defects (refraction), cataract, glaucoma and retinal disorders. Our products support doctors and patients to diagnose and treat these ailments efficiently and precisely, thus giving both of them clear benefits, not least by offering them a comprehensive disease management solution. The acquisition of Carl Zeiss Surgical has strengthened our leading market and competitive position for devices and systems in ophthalmic surgery.  Furthermore, we have secured an outstanding starting position in the growth market of neuro/ENT surgery. As the world‘s leading provider of surgical microscopes and visualisation solutions for these treatments, we will further expand our footprint in this area through organic growth and strategic expansion into adjacent market segments. In doing so, we want to develop into a solution provider in this area as well.  Carl Zeiss Meditec's medical technology portfolio is rounded off by innovative and promising future technologies such as intraoperative radiation therapy, which allows the targeted treatment of breast cancer and brain cancer during the operation stage itself.

  3. Quotes about Carl Zeiss Meditec

    1. I have come to rely on the Carl Zeiss Meditec brand for consistent and reliable technologies that are at the forefront of innovation and patient care.
      Ike K. Ahmed in Carl Zeiss Meditec Introduces New Suite of Ophthalmic Innovations
    2. Mr Taylor has been instrumental in making Meditec one of the leading companies in the field of ophthalmology in the past few years. My sincere thanks are due to him for his effort and dedication. I am pleased that Mr Taylor will continue to support us in the role of independent consultant and that we will be able to draw on his experience in future. Furthermore, I am convinced that we are ideally set with our current team to accelerate the proposed realisation of growth potential of Carl Zeiss Meditec.
      Michael Kaschke in Carl Zeiss Meditec reorganises management of its strategic business units
    3. Carl Zeiss Meditec received the highest overall Frost & Sullivan Competitive Metrics Score in the recently completed Strategic Analysis of Optical Imaging Technologies in U.S. Clinical Diagnostics Markets.
      In Frost & Sullivan Lauds Carl Zeiss Meditec for Dominating the OCT Market for Ophthalmic Applications