1. Carl Zeiss Meditec

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    1. Mentioned In 1291 Articles

    2. Optical coherence tomography shows early loss of the inferior temporal quadrant retinal nerve fiber layer in autosomal dominant optic atrophy

      Optical coherence tomography shows early loss of the inferior temporal quadrant retinal nerve fiber layer in autosomal dominant optic atrophy

      Purpose The aim of the study was to evaluate the relationship between visual function and retinal nerve fiber layer thickness (RNFLT) determined using Stratus optical coherence tomography (OCT) in patients with autosomal dominant optic atrophy (ADOA). Methods The study was a retrospective, institutional, and comparative case series. Thirty-six consecutive patients with ADOA and 72 age-matched normal controls were compared with regard to RNFLT, best-corrected visual acuity (BCVA), and visual field. Results The relative reduction of RNFLT of ADOA patients was most evident in the temporal quadrant (56.8 %), followed by the inferior (35.5 %), superior (27.2 %), and nasal quadrants ...

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    3. Baseline OCT Measurements in the Idiopathic Intracranial Hypertension Treatment Trial: Part II. Correlations and Relationship to Clinical Features

      Baseline OCT Measurements in the Idiopathic Intracranial Hypertension Treatment Trial: Part II. Correlations and Relationship to Clinical Features

      Purpose: The accepted method to evaluate and monitor papilledema, Frisén grading, is an ordinal approach based on descriptive features. Part I showed spectral domain (SD) optical coherence tomography (OCT) in a clinical trial setting provides reliable measurement of the effects of papilledema on the optic nerve head (ONH) and peripapillary retina, particularly if a 3D-segmentation method is used for analysis.1 We evaluated how OCT parameters are interrelated and how they correlate with vision and other clinical features in idiopathic intracranial hypertension (IIH). Methods: 126 subjects in the IIH Treatment Trial (IIHTT) OCT substudy had Cirrus SD-OCT optic disc ...

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    4. Baseline OCT Measurements in the Idiopathic Intracranial Hypertension Treatment Trial: Part I. Quality Control,Comparisons and Variability

      Baseline OCT Measurements in the Idiopathic Intracranial Hypertension Treatment Trial: Part I. Quality Control,Comparisons and Variability

      Purpose: Optical coherence tomography (OCT) has been utilized to investigate papilledema in single site, mostly retrospective studies. We investigated whether spectral domain OCT (SD-OCT), which provides thickness and volume measurements of the optic nerve and retina, could reliably demonstrate structural changes due to papilledema in a prospective multi-site clinical trial setting. Methods: At entry, 126 subjects in the Idiopathic Intracranial Hypertension Treatment Trial (IIHTT) with mild visual field loss had optic disc and macula scans using the Cirrus SD-OCT. Images were analyzed using the proprietary commercial and custom 3-D segmentation algorithms to calculate retinal nerve fiber layer (RNFL), total retinal ...

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    5. Reproducibility of Spectral-domain Optical Coherence Tomography RNFL Map for Glaucomatous and Fellow Normal Eyes in Unilateral Glaucoma

      Reproducibility of Spectral-domain Optical Coherence Tomography RNFL Map for Glaucomatous and Fellow Normal Eyes in Unilateral Glaucoma

      Purpose: To compare the reproducibility of the optical coherence tomography (OCT) retinal nerve fiber layer (RNFL) thickness map between glaucomatous and fellow normal eyes of unilateral glaucoma patients. Methods: In this prospective case-control study, Cirrus HD-OCT was performed for 79 unilateral glaucoma patients 3 times on the first visit and on 3 subsequent visits within a 2-month period. Test-retest standard deviation (TRT-SD) and tolerance limit based on the 1.645x[square root]2xTRT-SD formula were derived for RNFL thicknesses at the respective superpixels of the RNFL thickness map. Results: The TRT-SDs and tolerance limits of the glaucomatous eyes (TRT-SD: 2 ...

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    6. Wide-Field OCT Angiography at 400 KHz Utilizing Spectral Splitting

      Wide-Field OCT Angiography at 400 KHz Utilizing Spectral Splitting

      Optical angiography systems based on optical coherence tomography (OCT) require dense sampling in order to maintain good vascular contrast. We demonstrate a way to gain acquisition speed and spatial sampling by using spectral splitting with a swept source OCT system. This method splits the recorded spectra into two to several subspectra. Using continuous lateral scanning, the lateral sampling is then increased by the same factor. This allows increasing the field of view of OCT angiography, while keeping the same transverse resolution and measurement time. The performance of our method is demonstrated in vivo at different locations of the human retina ...

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    7. Macular parameters of Stratus optical coherence tomography for assessing glaucoma in high myopia

      Macular parameters of Stratus optical coherence tomography for assessing glaucoma in high myopia

      Background The aim was to assess the macular parameters of glaucoma in highly myopic subjects. Methods In a retrospective study, we enrolled 72 highly myopic eyes (spherical equivalent up to -6.00 D), of which 31 had early to moderate glaucoma and 41 formed a control group. The diagnosis of early to moderate glaucoma was based on glaucomatous visual-field defects with a mean deviation better than -12 dB. All patients underwent imaging with Stratus optical coherence tomography. We subsequently performed analysis for macular volume and thickness parameters between two groups. Results Using Stratus optical coherence tomography, we found significantly lower ...

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    8. Comparing focal and global responses on multifocal electroretinogram with retinal nerve fibre layer thickness by spectral domain optical coherence tomography in glaucoma

      Comparing focal and global responses on multifocal electroretinogram with retinal nerve fibre layer thickness by spectral domain optical coherence tomography in glaucoma

      Purpose To evaluate first and second order responses on multifocal electroretinogram (mfERG) and with retinal nerve fibre layer thickness (RNFL) on Cirrus spectral domain optical coherence tomography (SD-OCT) in glaucoma. Methods Patients (old and new) diagnosed with primary open angle glaucoma, primary angle closure glaucoma or normal tension glaucoma attending glaucoma services from November 2012 to January 2013 were screened. Ninety-seven eyes fulfilling inclusion criteria were evaluated by Humphrey visual field, Cirrus SD-OCT imaging and mfERG (Veris Science 5.1.10X; EDI, Redwood City, California, USA) for this observational cross-sectional study. The global and averaged quadrant-wise peak-to-trough amplitudes and peak ...

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    9. A comprehensive model for correcting RNFL readings of varying signal strengths in CIRRUS Optical Coherence Tomography (OCT)

      A comprehensive model for correcting RNFL readings of varying signal strengths in CIRRUS Optical Coherence Tomography (OCT)

      Purpose. Develop a model for the CIRRUSTM HD-OCT that allows for the comparison of retinal nerve fiber layer (RNFL) thickness measurements with dissimilar signal strengths (SS) and accounts for test-re-test variability. Methods. RNFLs were obtained in normals using the CIRRUSTM optic disc cube 200x200 protocol during a single encounter. Five RNFL scans were obtained with a SS of 9-10. Diffusion lens filters were used to degrade SS to obtain five scans at each SS group of 7-8, 5-6, and 3-4. The relationship between average RNFL thickness and SS was established and an equation was developed to allow for adjustment of ...

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    10. 1-15 of 1291 1 2 3 4 ... 84 85 86 »
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  2. About Carl Zeiss Meditec

    Carl Zeiss Meditec

    Carl Zeiss Meditec.  Ophthalmology Systems.  Carl Zeiss Meditec is an integrated medical technology company with two main areas of business activity.  In the field of ophthalmology we offer complete solutions for treating the four main eye ailments: vision defects (refraction), cataract, glaucoma and retinal disorders. Our products support doctors and patients to diagnose and treat these ailments efficiently and precisely, thus giving both of them clear benefits, not least by offering them a comprehensive disease management solution. The acquisition of Carl Zeiss Surgical has strengthened our leading market and competitive position for devices and systems in ophthalmic surgery.  Furthermore, we have secured an outstanding starting position in the growth market of neuro/ENT surgery. As the world‘s leading provider of surgical microscopes and visualisation solutions for these treatments, we will further expand our footprint in this area through organic growth and strategic expansion into adjacent market segments. In doing so, we want to develop into a solution provider in this area as well.  Carl Zeiss Meditec's medical technology portfolio is rounded off by innovative and promising future technologies such as intraoperative radiation therapy, which allows the targeted treatment of breast cancer and brain cancer during the operation stage itself.

  3. Quotes about Carl Zeiss Meditec

    1. I have come to rely on the Carl Zeiss Meditec brand for consistent and reliable technologies that are at the forefront of innovation and patient care.
      Ike K. Ahmed in Carl Zeiss Meditec Introduces New Suite of Ophthalmic Innovations
    2. Mr Taylor has been instrumental in making Meditec one of the leading companies in the field of ophthalmology in the past few years. My sincere thanks are due to him for his effort and dedication. I am pleased that Mr Taylor will continue to support us in the role of independent consultant and that we will be able to draw on his experience in future. Furthermore, I am convinced that we are ideally set with our current team to accelerate the proposed realisation of growth potential of Carl Zeiss Meditec.
      Michael Kaschke in Carl Zeiss Meditec reorganises management of its strategic business units
    3. Carl Zeiss Meditec received the highest overall Frost & Sullivan Competitive Metrics Score in the recently completed Strategic Analysis of Optical Imaging Technologies in U.S. Clinical Diagnostics Markets.
      In Frost & Sullivan Lauds Carl Zeiss Meditec for Dominating the OCT Market for Ophthalmic Applications