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    1. Mentioned In 98 Articles

    2. Assessing Computational Fractional Flow Reserve From Optical Coherence Tomography in Patients With Intermediate Coronary Stenosis in the Left Anterior Descending Artery

      Explore Circulation Cardiology
      Assessing Computational Fractional Flow Reserve From Optical Coherence Tomography in Patients With Intermediate Coronary Stenosis in the Left Anterior Descending Artery
      Background Intravascular optical coherence tomography (OCT) imaging provides limited information on the functional assessment of coronary stenosis. We evaluated a new approach to OCT imagebased computation modeling, which can be used to estimate the fractional flow reserve (FFR) in patients with intermediate coronary stenosis. Methods and Results Ninety-two patients with intermediate diameter stenosis in the left anterior descending artery underwent both FFR measurement with pressure wires and OCT examination. Using ...
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      Mentions: Cardiovascular Research Foundation Yonsei University Jung-Sun Kim

    3. Evaluation of Early Healing Profile and Neointimal Transformation Over 24 Months Using Longitudinal Sequential Optical Coherence Tomography Assessments and 3-Year Clinical Results of the New Dual-Therapy Endothelial Progenitor Cell Capturing Sirolimus-Elu

      Explore Circulation Cardiology
      Evaluation of Early Healing Profile and Neointimal Transformation Over 24 Months Using Longitudinal Sequential Optical Coherence Tomography Assessments and 3-Year Clinical Results of the New Dual-Therapy Endothelial Progenitor Cell Capturing Sirolimus-Elu
      Background Current monotherapy drug-eluting stents are associated with impaired healing, neoatherosclerosis, and late stent thrombosis. The healing profile and neointimal transformation of the first dual-therapy endothelial progenitor cellcapturing sirolimus-eluting stent are unknown. Methods and Results In this prospective, single-center study, 61 patients treated with the Combo stent had optical coherence tomography at baseline, early follow-up (4 monthly groups in a 1:2:2:1 ratio from 2 to 5 months ...
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      Mentions: Columbia University Mount Sinai School of Medicine Cardiovascular Research Foundation

    4. Understanding Why and When Optical Coherence Tomography Does Not Detect Vulnerable Plaques Is It Important?

      Explore Circulation Cardiology
      Understanding Why and When Optical Coherence Tomography Does Not Detect Vulnerable Plaques Is It Important?
      The goal of research into the in vivo detection of vulnerable plaques is to provide a clinician with a diagnostic tool that identifies vulnerable plaques prospectively to prevent acute events. This tool must have both a high positive predictive value and a high negative predictive value in the clinical setting (not just against histopathology) and cannot require specific expertise or core-laboratory analysis to determine whether a plaque should be treated ...
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      Mentions: Cardiovascular Research Foundation Gary S. Mintz

    5. Spontaneous coronary artery dissection and healing documented by optical coherence tomography

      Explore scielo.br Cardiology
      Spontaneous coronary artery dissection and healing documented by optical coherence tomography
      An otherwise healthy 57-year-old female patient with no risk factors for coronary artery disease presented to the emergency room with acute chest pain. The patient had been taking appetite suppressant (dimethylamylamine, Oxyelite Pro, (USP Labs) for the last 7 days. 1 , 2 Electrocardiography showed no abnormalities although both serum creatinine kinase-MB (3.59ng/mL) and troponin I (8,310pg/mL) were elevated. Coronary angiography revealed extensive and abrupt lumen narrowing ...
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      Mentions: Cardiovascular Research Foundation Gary S. Mintz

    7. Very, very late stent thrombosis triggered by in-stent neoatherosclerosis: optical coherence tomography findings

      Explore Termedia Cardiology
      Very, very late stent thrombosis triggered by in-stent neoatherosclerosis: optical coherence tomography findings
      A 64-year-old woman with dyslipidemia, hypertension and type 2 diabetes plus an existing 4.0-mm 28-mm bare-metal stent (BMS; Multilink Penta, Abbott Vascular, US) deployed over 10 years ago in the right coronary artery (RCA) was admitted to our emergency department with inferolateral and posterior ST-segment elevation acute myocardial infarction. Coronary angiography showed occlusion and thrombotic plaque in the mid RCA at the site of the prior stent implantation. After ...
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      Mentions: University of Montreal Cardiovascular Research Foundation

    8. Update on Intracoronary Optical Coherence Tomography: a Review of Current Concepts

      Explore Home - Springer Cardiology
      Update on Intracoronary Optical Coherence Tomography: a Review of Current Concepts
      Purpose of review The advent of intracoronary optical coherence tomography (OCT) has been a significant leap forward in the ability to visualize coronary structures with unprecedented resolution. However, the clinical application of this imaging modality has lagged behind rapid technological advances. One of the main reasons for the lack of wider clinical uptake has been the paucity of appropriately designed prospective randomized studies to demonstrate the impact of OCT on ...
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      Mentions: Cardiovascular Research Foundation Gary S. Mintz Gregg W. Stone

    9. The Mystery of Spotty Calcification Can We Solve It by Optical Coherence Tomography?

      Explore Circulation Cardiology
      The Mystery of Spotty Calcification Can We Solve It by Optical Coherence Tomography?
      Spotty calcification has recently been introduced as a marker of plaque vulnerability in patients presenting with acute coronary syndrome undergoing invasive and noninvasive coronary imaging, 1 and it has been suggested to be of predictive value for percent atheroma volume with greater progression. 2 Several pathological and clinical studies applying computed tomography (CT) and intravascular ultrasound (IVUS) demonstrated that spotty calcification is more frequently observed in lesions with plaque rupture ...
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      Mentions: Cardiovascular Research Foundation Renu Virmani Michael Joner

    10. Optical coherence tomography-guided percutaneous coronary intervention in pre-terminal chronic kidney disease with no radio-contrast administration

      Explore Oxford Journals Cardiology , Urology
      Optical coherence tomography-guided percutaneous coronary intervention in pre-terminal chronic kidney disease with no radio-contrast administration
      A 67-year-old man with advanced chronic kidney disease (CKD) (creatinine = 4.5 mg/dL, eGFR = 13 mL/min/1.73 m 2 ) not requiring haemodialysis presented with progressive angina. Diagnostic angiography with ultra-low radio-contrast volume (12 mL, contrast volume/eGFR ratio 1) revealed significant stenosis in the left anterior descending (LAD) artery ( Panel A ). The lesion was haemodynamically significant (fractional flow reserve: 0.77). Post-angiography, the
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      Mentions: Cardiovascular Research Foundation University of Sydney Martin B. Leon

    11. Comparison of Stent Expansion Guided by Optical Coherence Tomography Versus Intravascular Ultrasound : The ILUMIEN II Study (Observational Study of Optical Coherence Tomography [OCT] in Patients Undergoing Fractional Flow Reserve [FFR] and Percutaneous Co

      Explore ScienceDirect Cardiology
      Comparison of Stent Expansion Guided by Optical Coherence Tomography Versus Intravascular Ultrasound : The ILUMIEN II Study (Observational Study of Optical Coherence Tomography [OCT] in Patients Undergoing Fractional Flow Reserve [FFR] and Percutaneous Co
      Background The most important predictor of adverse outcomes (thrombosis and restenosis) after stent implantation with IVUS guidance is the degree of stent expansion achieved. Methods We compared the relative degree of stent expansion (defined as the minimal stent area divided by the mean of the proximal and distal reference lumen areas) after OCT-guided stenting in patients in the ILUMIEN (Observational Study of Optical Coherence Tomography [OCT] in Patients Undergoing Fractional ...
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      Mentions: Case Western Reserve University Columbia University Cardiovascular Research Foundation

    12. Clinical Impact of OCT Findings During PCI: The CLI-OPCI II Study

      Explore ScienceDirect Cardiology
      Clinical Impact of OCT Findings During PCI: The CLI-OPCI II Study
      Objectives The goal of this study was to assess the clinical impact of optical coherence tomography (OCT) findings during percutaneous coronary intervention (PCI). Background OCT provides unprecedented high-definition visualization of plaque/stent structures during PCI; however, the impact of OCT findings on outcome remains undefined. Methods In the context of the multicenter CLI-OPCI (Centro per la Lotta contro lInfartoOptimisation of Percutaneous Coronary Intervention) registry, we retrospectively analyzed patients undergoing end-procedural ...
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      Mentions: Cardiovascular Research Foundation Gary S. Mintz Corrado Tamburino

    13. Optical Coherence Tomography and Virtual-Histology Intravascular Ultrasound Strange Bedfellows? … or Not?

      Explore Circulation Cardiology
      Optical Coherence Tomography and Virtual-Histology Intravascular Ultrasound Strange Bedfellows? … or Not?
      The ultimate goal of studies such as the one by Brown et al 1 in this issue of Circulation: Cardiovascular Imaging is to provide the clinician with a diagnostic tool that identifies high-risk plaques prospectively to treat and prevent acute events. This tool must have a high positive predictive value and negative predictive value in the clinical setting and not require specific expertise or core-laboratory analysis to determine whether a ...
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      Mentions: Cardiovascular Research Foundation Gary S. Mintz

    15. Multi-laboratory inter-institute reproducibility study of IVOCT and IVUS assessments using published consensus document definitions

      Explore ehjcimaging.oxfordjournals.org Cardiology
      Multi-laboratory inter-institute reproducibility study of IVOCT and IVUS assessments using published consensus document definitions
      Aims The aim of this study was to investigate the reproducibility of intravascular optical coherence tomography (IVOCT) assessments, including a comparison to intravascular ultrasound (IVUS). Intra-observer and inter-observer variabilities of IVOCT have been previously described, whereas inter-institute reliability in multiple laboratories has never been systematically studied. Methods and results In 2 independent laboratories with intravascular imaging expertise, 100 randomized matched data sets of IVOCT and IVUS images were analysed by ...
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      Mentions: Guillermo J. Tearney Brett E. Bouma Columbia University

    16. Excimer Laser Angioplasty–Facilitated Fracturing of Napkin-Ring Peri-Stent Calcium in a Chronically Underexpanded Stent Documentation by Optical Coherence Tomography

      Explore interventions.onlinejacc.org Cardiology
      Excimer Laser Angioplasty–Facilitated Fracturing of Napkin-Ring Peri-Stent Calcium in a Chronically Underexpanded Stent Documentation by Optical Coherence Tomography
      A 79-year-old man underwent stent implantation into a severely calcified proximal left anterior descending coronary lesion ( Figure 1 ) in December 2012 followed by restenting in March 2014 to treat in-stent restenosis ( Figure 2 ), both without full balloon expansion. Optical coherence tomography (OCT) documented thick, peri-stent napkin-ring calcium. He was admitted for recurrent unstable angina in April 2014. After initial treatment with excimer laser coronary angioplasty (ELCA; 1.4 mm, Spectranetics ...
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      Mentions: Columbia University Cardiovascular Research Foundation Gary S. Mintz
    17. 1-15 of 98 1 2 3 4 5 6 7 »
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  4. About Cardiovascular Research Foundation

    Cardiovascular Research Foundation

    Cardiovascular Research Foundation (CRF) strives to improve the quality of life for patients with cardiovascular disease. Our goal is to advance the development and use of safe and effective minimally invasive cardiovascular treatments.  In addition to its world-renowned Core Labs, and the many ground-breaking studies and trials conducted under the Foundation's auspices each year, CRF also sponsors a number of patient-based special projects such as the Women's Health Initiative. Furthermore, through its Data Coordinating and Analysis Center, CRF maintains a vast database of clinical inquiry and outcomes. This important database has been created to track the real-world, long-term effectiveness of new treatment models.
    CRF's dedication to research and education is demonstrated at the annual Transcatheter Cardiovascular Therapeutics (TCT) symposium where CRF's distinguished faculty joins forces with more than 600 of the world's leading cardiologists to teach, share and discuss the latest techniques and developments in the field with over 11,000 symposium participants from across the globe. Where once it took years for such theories and practices to achieve currency in the medical community, TCT now ensures the timely dissemination of this critical body of research and therapeutic practice. It is an exchange, as Dr Leon says, "that influences the way hundreds of thousands of patients are treated every year."

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