1. Cardiff University

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    1. Mentioned In 70 Articles

    2. OCT-GAN: single step shadow and noise removal from optical coherence tomography images of the human optic nerve head

      Explore OSA | OSA Publishing Ophthalmology
      OCT-GAN: single step shadow and noise removal from optical coherence tomography images of the human optic nerve head
      Speckle noise and retinal shadows within OCT B-scans occlude important edges, fine textures and deep tissues, preventing accurate and robust diagnosis by algorithms and clinicians. We developed a single process that successfully removed both noise and retinal shadows from unseen single-frame B-scans within 10.4ms. Mean average gradient magnitude (AGM) for the proposed algorithm was 57.2% higher than current state-of-the-art, while mean peak signal to noise ratio (PSNR), contrast ...
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      Mentions: Heidelberg Engineering Cardiff University Medical University of Vienna

    3. Electrically pumped continuous-wave O-band quantum-dot superluminescent diode on silicon

      Explore OSA | OSA Publishing Broadband Sources
      Electrically pumped continuous-wave O-band quantum-dot superluminescent diode on silicon
      High-power, broadband quantum-dot (QD) superluminescent diodes (SLDs) are ideal light sources for optical coherence tomography (OCT) imaging systems but have previously mainly been fabricated on native GaAs- or InP-based substrates. Recently, significant progress has been made to emigrate QD SLDs from native substrates to silicon substrates. Here, we demonstrate electrically pumped continuous-wave InAs QD SLDs monolithically grown on silicon substrates with significantly improved performance thanks to the achievement of a ...
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      Mentions: University College London Cardiff University

    4. Deep learning algorithms to isolate and quantify the structures of the anterior segment in optical coherence tomography images

      Explore BJO Online Ophthalmology
      Deep learning algorithms to isolate and quantify the structures of the anterior segment in optical coherence tomography images
      Background/Aims Accurate isolation and quantification of intraocular dimensions in the anterior segment (AS) of the eye using optical coherence tomography (OCT) images is important in the diagnosis and treatment of many eye diseases, especially angle-closure glaucoma. Method In this study, we developed a deep convolutional neural network (DCNN) for the localisation of the scleral spur; moreover, we introduced an information-rich segmentation approach for this localisation problem. An ensemble of ...
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      Mentions: Cardiff University Singapore Eye Research Institute National University of Singapore

    5. DeshadowGAN: A Deep Learning Approach to Remove Shadows from Optical Coherence Tomography Images

      Explore arxiv.org Ophthalmology
      DeshadowGAN: A Deep Learning Approach to Remove Shadows from Optical Coherence Tomography Images
      Purpose: To remove retinal shadows from optical coherence tomography (OCT) images of the optic nerve head (ONH). Methods: 2328 OCT images acquired through the center of the ONH using a Spectralis OCT machine for both eyes of 13 subjects were used to train a generative adversarial network (GAN) using a custom loss function.Image quality was assessed qualitatively (for artifacts) and quantitatively using the intralayer contrast € a measure of shadow ...
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      Mentions: Cardiff University Nanyang Technological University National University of Singapore

    6. Disease classification of macular Optical Coherence Tomography scans using deep learning software: validation on independent, multi-centre data

      Explore arxiv.org
      Disease classification of macular Optical Coherence Tomography scans using deep learning software: validation on independent, multi-centre data
      Purpose: To evaluate Pegasus-OCT, a clinical decision support software for the identification of features of retinal disease from macula OCT scans, across heterogenous populations involving varying patient demographics, device manufacturers, acquisition sites and operators. Methods: 5,588 normal and anomalous macular OCT volumes (162,721 B-scans), acquired at independent centres in five countries, were processed using the software. Results were evaluated against ground truth provided by the dataset owners. Results ...
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      Mentions: Cardiff University Kings College London

    7. Lid-parallel conjunctival fold (LIPCOF) morphology imaged by optical coherence tomography and its relationship to LIPCOF grade

      Explore ScienceDirect Ophthalmology
      Lid-parallel conjunctival fold (LIPCOF) morphology imaged by optical coherence tomography and its relationship to LIPCOF grade
      Purpose Lid-parallel conjunctival folds (LIPCOF) are a well-accepted clinical sign in dry eye diagnosis. Commonly, LIPCOF is classified by grading the number of folds observed by slit-lamp microscope. This study investigated the relationship between subjective grading scale and LIPCOF morphology imaged by optical coherence tomography (OCT). Methods Temporal and nasal LIPCOF of 42 subjects (mean age 27.38.4 (SD) years; 13M, 29F) were observed and classified by an experienced ...
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      Mentions: University of Waterloo Cardiff University Carl Zeiss Meditec

    9. Automated Retinal Layer Segmentation Using Spectral Domain Optical Coherence Tomography: Evaluation of Inter-Session Repeatability and Agreement between Devices

      Explore Journals | PLOS Ophthalmology
      Automated Retinal Layer Segmentation Using Spectral Domain Optical Coherence Tomography: Evaluation of Inter-Session Repeatability and Agreement between Devices
      ...s (n = 25) were recruited from staff, students and volunteers at the School of Optometry and Vision Sciences, Cardiff University. All participants had a corrected visual acuity of 0.0 logMAR (20/20) or better using a hig...
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      Mentions: National Institutes of Health Heidelberg Engineering Topcon Medical Systems

    10. Adaptive-Weighted Bilateral Filtering and Other Pre-processing Techniques for Optical Coherence Tomography

      Explore Elsevier
      Adaptive-Weighted Bilateral Filtering and Other Pre-processing Techniques for Optical Coherence Tomography
      This paper presents novel pre-processing image enhancement algorithms for retinal optical coherence tomography (OCT). These images contain a large amount of speckle causing them to be grainy and of very low contrast. To make these images valuable for clinical interpretation, we propose a novel method to remove speckle, while preserving useful information contained in each retinal layer. The process starts with multi-scale despeckling based on a dual-tree complex wavelet transform ...
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      Mentions: Cardiff University

    13. Transcutaneous immunization using microneedles and cubosomes: Mechanistic investigations using Optical Coherence Tomography and Two-Photon Microscopy

      Explore ScienceDirect
      Transcutaneous immunization using microneedles and cubosomes: Mechanistic investigations using Optical Coherence Tomography and Two-Photon Microscopy
      ...nal School of Pharmacy, University of Otago, New Zealand * ^b School of Pharmacy and Pharmaceutical Sciences, Cardiff University, United Kingdom * ^c Laboratory of Cellular Dynamics, Immunology Frontier Research Center, ...
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      Mentions: Cardiff University University of Copenhagen Osaka University

    14. Cardiff School of Optometry and Vision Sciences PhD Studentship in Ophthalmic Clinical Research (PhD Studentship)

      Explore Cardiff University Ophthalmology , Jobs & Studentships
      Cardiff School of Optometry and Vision Sciences PhD Studentship in Ophthalmic Clinical Research (PhD Studentship)
      Applications are invited for this School funded PhD studentship entitled Quality of Life and Clinical Outcomes in Age-related Macular Degeneration scheduled to start in October 2013. The successful applicant will work with Dr Jennifer Acton in the Macular Disease Study Group based in the School of Optometry and Vision Sciences. The School is recognised as an international centre of excellence in basic and clinical research. The Macular Disease Group undertakes ...
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      Mentions: Cardiff University

    15. MedLumics Names Prof. Wolfgang Drexler President of Its Scientific Advisory Board

      Explore Optical Coherence Tomography News Other Business News
      MedLumics Names Prof. Wolfgang Drexler President of Its Scientific Advisory Board
      ...d an international scientific reputation. In 2006, he became head of the Biomedical Imaging department at the University of Cardiff in Wales, where he had been serving as one of the members of the governing research coun...
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      Mentions: Massachusetts Institute of Technology Cardiff University Medical University of Vienna

    16. Graphics processing unit-based dispersion encoded full-range frequency-domain optical coherence tomography

      Explore Linking to Scitation Content Ophthalmology
      Graphics processing unit-based dispersion encoded full-range frequency-domain optical coherence tomography
      Dispersion encoded full-range (DEFR) frequency-domain optical coherence tomography (FD-OCT) and its enhanced version, fast DEFR, utilize dispersion mismatch between sample and reference arm to eliminate the ambiguity in OCT signals caused by non-complex valued spectral measurement, thereby numerically doubling the usable information content. By iteratively suppressing asymmetrically dispersed complex conjugate artifacts of OCT-signal pulses the complex valued signal can be recovered without additional measurements, thus doubling the spatial signal range ...
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      Mentions: Cardiff University Medical University of Vienna K. U. Leuven
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  4. About Cardiff University

    Cardiff University

    Cardiff University is one of Britain’s major teaching and research universities. Located in the centre of the capital city of Wales, it has an international reputation for the quality of its work which attracts staff and students from around the world. Cardiff University School of Optometry and Vision Sciences.   The School is the only optometric training department in Wales, and one of the largest in the UK, with 28 academics, 4 clinicians, 17 post-doctoral fellows, 42 post-graduate students, and 12 School staff.

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    4. Automated Retinal Layer Segmentation Using Spectral Domain Optical Coherence Tomography: Evaluation of Inter-Session Repeatability and Agreement between Devices
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    5. DeshadowGAN: A Deep Learning Approach to Remove Shadows from Optical Coherence Tomography Images
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