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2. Macular Structure and Microvasculature Changes in AIDS-Related Cytomegalovirus Retinitis Using Optical Coherence Tomography Angiography
  
  Explore Frontiers Sep 4 2021 Ophthalmology
  
  ...e and inactive CMVR) and healthy controls treated in the Department of Ophthalmology, Beijing Youan Hospital, Capital Medical University between August 25, 2019, and October 18, 2019, were recruited. All OCTA parameters,...
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3. Macrocalcification of intracranial vertebral artery may be related to in-stent restenosis: lessons learned from optical coherence tomography
  
  Explore jnis.bmj.com Aug 12 2021 Cardiology
  
  Background: Calcification has been proven to be a marker of atherosclerosis and is related to an increased risk of ischemic stroke. Additionally, calcification was reported to be prevalent in patients with stenotic lesions of the intracranial vertebral artery. Thus, reliable imaging facilities for evaluating plaque calcification have remarkable significance in guiding stenting and predicting patient outcomes. Optical coherence tomography (OCT) has a unique advantage in its ability to detect calcium ...
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4. Effect of Alirocumab on Coronary Plaque in Patients With Coronary Artery Disease Assessed by Optical Coherence Tomography
  
  Explore Home | Research Square Jul 20 2021 Cardiology
  
  Background Proprotein convertase subtilisin kexin type 9 (PCSK9) inhibitors have been demonstrated with significant greater reduction of LDL cholesterol levels and cardiovascular events, compared with standard statin therapy. However, the evidence on the impact of PCSK9 inhibitors on coronary plaque composition and morphology are limited. Methods In this prospective, open-label, randomized study, eligible patients with intermediate coronary lesions and elevated LDL cholesterol values were randomized to either alirocumab 75 mg ...
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5. Frequency-Domain Optical Coherence Tomography for Intracranial Atherosclerotic Stenosis: Feasibility, Safety, and Preliminary Experience
  
  Explore Frontiers Jul 6 2021 Cardiology
  
  Background: Despite advances in non-invasive imaging, the characterization of atherosclerotic plaque remains superior with frequency-domain optical coherence tomography (FD-OCT) in the clinical coronary and experimental cerebrovascular literature. An assessment of the feasibility and safety of FD-OCT for intracranial atherosclerotic stenosis (ICAS) is desirable. Methods: We analyzed a cohort of all consecutive FD-OCT evaluations for ICAS performed at our institution from April 2017 to August 2018 (16 months) in patients who ...
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  Mentions: Brigham and Women’s Hospital Capital Medical University Harvard University
6. Retinal Microvascular Changes in Uveal Melanoma Following Conbercept Injection after Plaque Radiotherapy as Detected By Optical Coherence Tomographic Angiography
  
  Explore LWW Online Jun 24 2021 Ophthalmology
  
  Purpose: To investigate macular microvascular characteristics imaged by optical coherence tomography angiography (OCTA) in uveal melanoma (UM) patients following Conbercept injections after plaque radiotherapy. Methods: Prospective comparative analysis comprising 15 UM patients with Conbercept injections and 30 patients without Conbercept injections after plaque radiotherapy by OCTA. The Conbercept group received intravitreal Conbercept injections at the time of plaque removal, 1 month, 3 months, 6 months , 9 months and 12 months ...
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7. Non-invasive Diagnosis and Prognosis Values of 3D Pseudocontinuous Arterial Spin Labeling and Optical Coherence Tomography Angiography in Proliferative Diabetic Retinopathy
  
  Explore Frontiers Jun 24 2021 Ophthalmology
  
  Background: 3D Pseudocontinuous Arterial Spin Labeling (3D-PCASL) MRI and optical coherence tomography angiography (OCTA) have been applied to detect ocular blood flow (BF). We aim to characterize the ocular BF in diabetic retinopathy (DR) using 3D-PCASL and OCTA, to discuss the relationship between ocular and cerebral BF, and to evaluate their potential utility to assess the severity of DR. Methods: A total of 66 participants (132 eyes) were included. Seventy-two ...
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8. Prognostic Utility of Optical Coherence Tomography for Visual Outcome After Extended Endoscopic Endonasal Surgery for Adult Craniopharyngiomas
  
  Explore Home | Research Square Jun 11 2021 Neurology , Ophthalmology
  
  Optical coherence tomography (OCT) serving as a novel high resolution imaging technique can assess the retinal morphology. At present, a few studies are reported with limited evidence on the predictive value of OCT for visual outcome after optic nerve decompression. This study aims to utilize the largest series of adult craniopharyngiomas to evaluate the association between OCT parameters and visual outcome following the extended endoscopic endonasal surgery (EEES). From October ...
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9. Investigation of Macular Choroidal Thickness and Blood Flow Change by Optical Coherence Tomography Angiography After Posterior Scleral Reinforcement
  
  Explore Frontiers May 23 2021 Ophthalmology
  
  Purpose: This work aimed to study the effect of posterior scleral reinforcement (PSR) on choroidal thickness (CT) and blood flow. Methods: This study included 25 eyes of 24 patients with high myopia ( -6.0 dioptres or axial length 26.0 mm) who underwent PSR surgery. All patients completed the 1-month follow-up visit. Myopic macular degeneration (MMD) was graded according to the International Meta-Analysis for Pathologic Myopia (META-PM) classification based on ...
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10. Optical Coherence Tomography of Plaque Erosion and Thrombus in Severe Vertebral Artery Stenosis
  
  Explore MDPI Open Access Journals Platform Apr 6 2021 Cardiology
  
  A 69-year-old male presented with medically refractory vertebrobasilar insufficiency and paroxysmal subjective dizziness for six months. Severe stenosis of a dominant left V2 vertebral artery segment was identified on digital subtraction angiography (DSA) with an irregular intraluminal filling defect immediately above the stenosis. Optical coherence tomography (OCT) demonstrated a normal lumen at the distal end, with red thrombus detected distal to the stenosis. Atherosclerotic plaque containing fibro-lipid was also identified ...
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11. Neovascularization in Human Intracranial Atherosclerotic In-Stent Restenosis
  
  Explore MDPI Open Access Journals Platform Feb 17 2021 Cardiology
  
  Optical coherence tomography (OCT) has seen widespread use in cardiovascular and interventional endovascular imaging. While scattered reports of intracranial usage have been reported for the assessment of atherosclerotic stenosis, nutrifying neovasculature supplying plaque and neointima have not been demonstrated until now. We report the first in-vivo illustration of this phenomenon, which is a high-resolution depiction of a critical pathway for in-stent restenosis.
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12. Plaque characteristics in patients with ST-segment elevation myocardial infarction and early spontaneous reperfusion
  
  Explore eurointervention.pcronline.com Jan 27 2021 Cardiology
  
  Background: Early spontaneous reperfusion (ESR) is not an uncommon phenomenon in clinical settings. Aims: To detect potential mechanisms of early spontaneous reperfusion in patients with STEMI. Methods: This prospective study enrolled a total of 241 consecutive patients with STEMI undergoing optical coherence tomography (OCT) from July 2016 to August 2019. Forty-five (18.7%) met angiographic ESR criteria (TIMI-3 flow on the initial angiogram). Among those without ESR (TIMI-0 flow on ...
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13. The relationship between residual cholesterol risk and plaque characteristics in patients with acute coronary syndrome: Insights from an optical coherence tomography study
  
  Explore atherosclerosis-journal.com Nov 29 2020 Cardiology
  
  Background and aims The impact of residual cholesterol risk (RCR) on plaque characteristics is not fully understood. The study aims to explore the relationship between RCR and plaque features in patients presenting with acute coronary syndrome (ACS). Methods All ACS patients undergoing pre-intervention optical coherence tomography (OCT) with high-sensitivity C-reactive protein (hs-CRP) 2 mg/L on admission were retrospectively enrolled from January to December 2017, at Beijing Anzhen Hospital, Capita ...
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14. Correlation between intracranial vertebral artery stenosis diameter measured by digital subtraction angiography and cross-sectional area measured by optical coherence tomography
  
  Explore jnis.bmj.com Nov 25 2020 Neurology , Ophthalmology
  
  Background: Intracranial vertebral artery (V4 segment) stenosis quantification traditionally uses the narrowest stenosis diameter. However, the stenotic V4 lumen is commonly irregularly shaped. Optical coherence tomography (OCT) allows a more precise calculation of V4 geometry. We compared the narrowest diameter stenosis (DS), measured by digital subtraction angiography (DSA), with the area stenosis (AS), measured by OCT. We hypothesized that DS is the gold standard for measuring the degree of stenosis ...
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15. Optical coherence tomography angiography characteristics of choroidal melanoma
  
  Explore Nature Publishing Group Nov 9 2020 Ophthalmology
  
  Purpose The purpose of this study is to evaluate tumour vasculature with optical coherence tomography angiography (OCTA) in malignant choroidal melanoma (CM). Materials and methods Patients with unilateral CM were included in this cross-sectional observational clinical study. Applying OCTA systems operating at 840-nm wavelengths, eyes with CM were imaged. The primary main outcome measures were OCTA images, qualitative evaluation of macular and tumour vasculature, quantitative vascular density (VD), perfusion density ...
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16. Traumatic Macular Hole: Clinical Management and Optical Coherence Tomography Features
  
  Explore Hindawi Publishing Corporation Oct 26 2020 Ophthalmology
  
  The complex and uncertain prognosis of traumatic macular hole (TMH) makes it a difficult and challenging problem in clinical management. The features of spontaneously closed TMH and the time of vitrectomy remain unclear. This retrospective study aimed to demonstrate the optical coherence tomography (OCT) features of TMH, explore the relationship between OCT parameters and visual outcomes, and further evaluate the therapeutic effect of surgical management. Seventeen TMH patients were included ...
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