1. California Institute of Technology

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    1. Mentioned In 55 Articles

    2. Notal Vision Announces Appointment of Dr. Susan Orr as Chief Executive Officer

      Notal Vision Announces Appointment of Dr. Susan Orr as Chief Executive Officer
      ...a Masters in Electrical Engineering from Stanford University and a PhD in Computational Neuroscience from the California Institute of Technology.  This rare combination will enable her to apply her unique skill set while...
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    3. Polymeric endovascular strut and lumen detection algorithm for intracoronary optical coherence tomography images

      Polymeric endovascular strut and lumen detection algorithm for intracoronary optical coherence tomography images
      Polymeric endovascular implants are the next step in minimally invasive vascular interventions. As an alternative to traditional metallic drug-eluting stents, these often-erodible scaffolds present opportunities and challenges for patients and clinicians. Theoretically, as they resorb and are absorbed over time, they obviate the long-term complications of permanent implants, but in the short-term visualization and therefore positioning is problematic. Polymeric scaffolds can only be fully imaged using optical coherence tomography (OCT ...
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    4. Virtual phase conjugation based optical tomography for single-shot three-dimensional imaging

      Virtual phase conjugation based optical tomography for single-shot three-dimensional imaging
      We propose a virtual phase conjugation (VPC) based optical tomography (VPC-OT) for realizing single-shot optical tomographic imaging systems. Using a computer-based numerical beam propagation, the VPC combines pre-modulation and post-demodulation of the probe beams wavefront, which provides an optical sectioning capability for resolving the depth coordinates. In VPC-OT, the physical optical microscope system and VPC are coupled using digital holography. Therefore, in contrast to conventional optical tomographic imaging (OTI) systems ...
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    5. Advanced Monte Carlo Simulation and Machine Learning for Frequency Domain Optical Coherence Tomography

      Advanced Monte Carlo Simulation and Machine Learning for Frequency Domain Optical Coherence Tomography
      Optical Coherence Tomography(OCT) is a popular, rapidly growing imaging technique with an increasing number of bio-medical applications due to its noninvasive nature. However, there are three major challenges in understanding and improving an OCT system: (1) Obtaining an OCT image is not easy. It either takes a real medical experiment or requires days of computer simulation. Without much data, it is difficult to study the physical processes underlying OCT ...
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    6. Optical Coherence Tomography (OCT) System With Improved Motion Contrast

      Optical Coherence Tomography (OCT) System With Improved Motion Contrast
      This disclosure relates to the field of Optical Coherence Tomography (OCT). This disclosure particularly relates to an OCT system with improved motion contrast. This disclosure particularly relates to motion contrast methods for such OCT systems.
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    7. Optical Coherence Tomography (OCT) System With PHASE-SENSITIVE B-SCAN Registration

      Optical Coherence Tomography (OCT) System With PHASE-SENSITIVE B-SCAN Registration
      This disclosure relates to the field of Optical Coherence Tomography (OCT). This disclosure particularly relates to an OCT system having a configuration that uses a phase sensitive B-scan registration method. In this disclosure, an OCT system may have a configuration that scans a physical object, acquires OCT signals to form B-scans, uses these B-scans to determine an optimal shift in an axial direction by using total phase error between B-scans ...
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    8. Compressive sensing optical coherence tomography using randomly accessible lasers

      Compressive sensing optical coherence tomography using randomly accessible lasers
      We propose and demonstrate a novel a compressive sensing swept source optical coherence tomography (SSOCT) system that enables high speed images to be taken while maintaining the high resolution offered from a large bandwidth sweep. Conventional SSOCT systems sweep the optical frequency of a laser (t) to determine the depth of the reflectors at a given lateral location. A scatterer located at delay appears as a sinusoid cos ((t) ) at ...
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    9. Improved in vivo imaging of human blood circulation in the chorioretinal complex using phase variance method with new phase stabilized 1 μm swept-source optical coherence tomography (pv-SSOCT)

      Improved in vivo imaging of human blood circulation in the chorioretinal complex using phase variance method with new phase stabilized 1 μm swept-source optical coherence tomography (pv-SSOCT)
      We demonstrate the feasibility of our newly developed phase stabilized high-speed (100 kHz A-scans/s) 1 m sweptsource optical coherence tomography (SSOCT) system with the phase-variance based motion contrast method for visualization of human chorioretinal complex microcirculation. Compared to our previously reported spectral domain (spectrometer based) phase-variance (pv)-SDOCT system it has advantages of higher sensitivity, reduced fringe washout for high blood flow speeds and deeper penetration in choroid. High ...
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    10. Swept-frequency semiconductor laser coupled to microfabricated biomolecular sensor and methods related thereto

      Swept-frequency semiconductor laser coupled to microfabricated biomolecular sensor and methods related thereto
      An optoelectronic swept-frequency semiconductor laser coupled to a microfabricated optical biomolecular sensor with integrated resonator and waveguide and methods related thereto are described. Biomolecular sensors with optical resonator microfabricated with integrated waveguide operation can be in a microfluidic flow cell.
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    11. 1-15 of 55 1 2 3 4 »
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  2. About California Institute of Technology

    California Institute of Technology

    California Institute of Technology is a private research university located in Pasadena, California. The Institute maintains a strong emphasis on the natural sciences and engineering, and operates and manages NASA's neighboring Jet Propulsion Laboratory. Caltech is a small school, with only about 2100 students (about 900 undergraduates and 1200 graduate students), but it is ranked number 2 in the world according to Global University Ranking and in the top ten universities worldwide by metrics such as Science Watch, Nobel Prizes, and general university rankings.