1. Brown University

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    1. Mentioned In 15 Articles

    2. Deep learning toolbox for automated enhancement, segmentation, and graphing of cortical optical coherence tomography microangiograms

      Explore OSA | OSA Publishing
      Deep learning toolbox for automated enhancement, segmentation, and graphing of cortical optical coherence tomography microangiograms
      Optical coherence tomography angiography (OCTA) is becoming increasingly popular for neuroscientific study, but it remains challenging to objectively quantify angioarchitectural properties from 3D OCTA images. This is mainly due to projection artifacts or tails underneath vessels caused by multiple-scattering, as well as the relatively low signal-to-noise ratio compared to fluorescence-based imaging modalities. Here, we propose a set of deep learning approaches based on convolutional neural networks (CNNs) to automated enhancement ...
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      Mentions: Brown University

    3. Morphological changes in intraretinal microvascular abnormalities after anti-VEGF therapy visualized on optical coherence tomography angiography

      Explore Eye and Vision Ophthalmology
      Morphological changes in intraretinal microvascular abnormalities after anti-VEGF therapy visualized on optical coherence tomography angiography
      Background To examine the baseline morphological characteristics and alterations in intraretinal microvascular abnormalities (IRMAs) in response to anti-vascular endothelial growth factor (anti-VEGF) treatment, documented by optical coherence tomography angiography (OCTA) in diabetic eyes. Methods In this retrospective study, IRMAs were evaluated with multimodal imaging (fundus photography, fluorescein angiography, OCTA) in treatment-nave diabetic eyes before and after anti-VEGF treatment for diabetic macular edema (DME) and/or proliferative diabetic retinopathy (PDR) and ...
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      Mentions: Yale University Andre J. Witkin Jay S. Duker

    4. Intravascular Imaging for Venous Interventions

      Explore Home - Springer Cardiology
      Intravascular Imaging for Venous Interventions
      Purpose of Review This review surveys the clinical landscape of intravascular imaging for endovenous interventions. Recent Findings Endovascular imaging has become increasingly important for diagnosing venous pathology and guiding venous interventions. In particular, intravascular ultrasound (IVUS) provides 3D high-resolution cross-sectional imaging of vessel and surrounding tissues, often in anatomic locations inaccessible to surface ultrasound, namely the superior vena cava, inferior vena cava, and caval-iliac veins. Summary Current well-established indications for ...
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      Mentions: Beth Israel Deaconess Medical Center Yale University Harvard University

    5. Topographic analysis of macular choriocapillaris flow deficits in diabetic retinopathy using swept–source optical coherence tomography angiography

      Explore journalretinavitreous.biomedcentral.com Ophthalmology
      Topographic analysis of macular choriocapillaris flow deficits in diabetic retinopathy using swept–source optical coherence tomography angiography
      Background The purpose of this study was to investigate the association between diabetic retinopathy (DR) severity and macular choriocapillaris (CC) flow deficit percentage (FD %) in different macular regions using swept-source optical coherence tomography angiography (SS-OCTA). Methods Diabetic patients with SS-OCTA images were graded by severity and retrospectively assessed. CC FD % was calculated in four different regions of the OCTA image: inner, middle, outer, and full-field region. The generalized estimating equations ...
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      Mentions: Massachusetts Institute of Technology James G. Fujimoto Yale University

    6. Diversity in optical coherence tomography normative databases: moving beyond race

      Explore Home - Springer Ophthalmology
      Diversity in optical coherence tomography normative databases: moving beyond race
      Normative databases of optical coherence tomography (OCT) metrics, such as retinal nerve fiber layer (RNFL) and macular thickness, are critical to clinical use of OCT imaging. In order to accurately represent the range of normal variation in patient populations, these normative databases must themselves be adequately diverse. Thus far, diversity in OCT normative databases has largely been defined as racial diversity. However, this has largely been based on self-reported race ...
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      Mentions: Tufts University Brown University Nadia K. Waheed

    7. Optimizing Percutaneous Coronary Intervention in Calcified Lesions Insights From Optical Coherence Tomography of Atherectomy

      Explore Circulation Cardiology
      Optimizing Percutaneous Coronary Intervention in Calcified Lesions Insights From Optical Coherence Tomography of Atherectomy
      Optimal coronary stent implantation is among the few successful strategies in preventing stent failures, notably in-stent restenosis and stent thrombosis. 1 Understanding the intravascular milieu is a prerequisite for optimization of percutaneous coronary intervention (PCI). Calcified lesions limit stent expansion, the most robust predictor of target lesion revascularization, and are thus associated with worst outcomes. 2 Coronary angiography is a poor discriminator of calcium distribution and thickness. Reliance on angiography ...
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      Mentions: Case Western Reserve University Brown University Hiram G. Bezerra

    8. Measurement of shear-induced diffusion of red blood cells using dynamic light scattering-optical coherence tomography

      Explore SPIE Digital Library
      Measurement of shear-induced diffusion of red blood cells using dynamic light scattering-optical coherence tomography
      Dynamic Light Scattering-Optical Coherence Tomography (DLS-OCT) takes the advantages of using DLS to measure particle flow and diffusion within an OCT resolution-constrained 3D volume, enabling the simultaneous measurements of absolute RBC velocity and diffusion coefficient with high spatial resolution. In this work, we applied DLS-OCT to measure both RBC velocity and the shear-induced diffusion coefficient within penetrating venules of the somatosensory cortex of anesthetized mice. Blood flow laminar profile measurements ...
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      Mentions: Massachusetts General Hospital Harvard University Boston University

    10. Optical coherence tomography imaging of capillary reperfusion after ischemic stroke

      Explore OSA | OSA Publishing Neurology
      Optical coherence tomography imaging of capillary reperfusion after ischemic stroke
      Although progress has been made for recanalization therapies after ischemic stroke, post-treatment imaging studies show that tissue reperfusion cannot be attained despite satisfactory recanalization in a significant percentage of patients. Hence, investigation of microcirculatory changes in both surface and deep cortical levels after ischemia reperfusion is important for understanding the post-stroke blood flow dynamics. In this study, we applied optical coherence tomography (OCT) imaging of cerebral blood flow for the ...
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      Mentions: Massachusetts General Hospital Harvard University Brown University

    13. Methods of Melanoma Detection

      Explore Home - Springer Dermatology
      Methods of Melanoma Detection
      Detection and removal of melanoma, before it has metastasized, dramatically improves prognosis and survival. The purpose of this chapter is to (1) summarize current methods of melanoma detection and (2) review state-of-the-art detection methods and technologies that have the potential to reduce melanoma mortality. Current strategies for the detection of melanoma range from population-based educational campaigns and screening to the use of algorithm-driven imaging technologies and performance of assays that ...
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      Mentions: Massachusetts General Hospital Oregon Health & Science University Stanford University

    14. Characterization of Knuckle (Garrod) Pads Using Optical Coherence Tomography In Vivo

      Explore subscribe.imngmedicalmedia.com Dermatology
      Characterization of Knuckle (Garrod) Pads Using Optical Coherence Tomography In Vivo
      To the Editor: Optical coherence tomography (OCT) is a noninvasive imaging technique that uses a low-power infrared laser light for cutaneous architecture visualization up to 2 mm in depth. Both malignant and nonmalignant lesions on OCT imaging have been correlated with histopathologic analysis. 1 We describe the diagnostic features of knuckle pads on OCT. A 43-year-old-man presented with warts on the right thumb and bilateral feet of several months duration ...
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      Mentions: Brown University Orit Markowitz
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  4. About Brown University

    Brown University

    Brown University is a private , Ivy League university located in Providence, Rhode Island.

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    1. Methods of Melanoma Detection
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    3. Diversity in optical coherence tomography normative databases: moving beyond race
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    4. Topographic analysis of macular choriocapillaris flow deficits in diabetic retinopathy using swept–source optical coherence tomography angiography
      3 articles also mentioned Yale University