1. British Columbia Cancer Agency

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    1. Mentioned In 36 Articles

    2. Diagnostic bronchoscopy--current and future perspectives

      Diagnostic bronchoscopy--current and future perspectives
      Lung cancer is the leading cause of cancer-related mortality worldwide. Standard bronchoscopy has limited ability to accurately localise and biopsy pulmonary lesions that cannot be directly visualised. The field of advanced diagnostic bronchoscopy is rapidly evolving due to advances in electronics and miniaturisation. Bronchoscopes with smaller outer working diameters, coupled with miniature radial and convex ultrasound probes, allow accurate central and peripheral pulmonary lesion localisation and biopsy while at the ...
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    3. Multimodal tissue imaging: using coregistered optical tomography data to estimate tissue autofluorescence intensity change due to scattering and absorption by neoplastic epithelial cells

      Multimodal tissue imaging: using coregistered optical tomography data to estimate tissue autofluorescence intensity change due to scattering and absorption by neoplastic epithelial cells
      Autofluorescence (AF) imaging provides valuable information about the structural and chemical states of tissue that can be used for early cancer detection. Optical scattering and absorption of excitation and emission light by the epithelium can significantly affect observed tissue AF intensity. Determining the effect of epithelial attenuation on the AF intensity could lead to a more accurate interpretation of AF intensity. We propose to use optical coherence tomography coregistered with ...
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    4. In vivo lung microvasculature visualized in three dimensions using fiber-optic color Doppler optical coherence tomography

      In vivo lung microvasculature visualized in three dimensions using fiber-optic color Doppler optical coherence tomography
      For the first time, the use of fiber-optic color Doppler optical coherence tomography (CDOCT) to map in vivo the three-dimensional (3-D) vascular network of airway segments in human lungs is demonstrated. Visualizing the 3-D vascular network in the lungs may provide new opportunities for detecting and monitoring lung diseases such as asthma, chronic obstructive pulmonary disease, and lung cancer. Our CDOCT instrument employs a rotary fiber-optic probe that provides simultaneous ...
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    5. Correction of autofluorescence intensity for epithelial scattering by optical coherence tomography: a phantom study

      Correction of autofluorescence intensity for epithelial scattering by optical coherence tomography: a phantom study
      In this paper, we conduct a phantom study for modeling the autofluorescence (AF) properties of tissue. A combined optical coherence tomography (OCT) and AF imaging system is proposed to measure the strength of the AF signal in terms of the scattering layer thickness and concentration. The combined AF-OCT system is capable of estimating the AF loss due to scattering in the epithelium using the thickness and scattering concentration calculated from ...
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    6. Lung vasculature imaging using speckle variance optical coherence tomography

      Lung vasculature imaging using speckle variance optical coherence tomography
      Architectural changes in and remodeling of the bronchial and pulmonary vasculature are important pathways in diseases such as asthma, chronic obstructive pulmonary disease (COPD), and lung cancer. However, there is a lack of methods that can find and examine small bronchial vasculature in vivo. Structural lung airway imaging using optical coherence tomography (OCT) has previously been shown to be of great utility in examining bronchial lesions during lung cancer screening ...
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    7. Postdoctoral Fellowship in the Integrative Oncolog Department at The Integrative Oncology Department at the British Columbia Cancer Agency

      Postdoctoral Fellowship in the Integrative Oncolog Department at The Integrative Oncology Department at the British Columbia Cancer Agency
      ...lumbia Canada V5Z 1L3 klemmen@bccancer.bc.ca Fax: 604-675-8099 The Integrative Oncology Department at the British Columbia Cancer Agency (Vancouver, BC) has an immediate opening for a Post-doctoral fellow. The Integr...
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    8. B.C. Cancer Research Center Receives CIHR Grant To Investigate High-Resolution OCT Imaging of Bronchial Epithelium

      B.C. Cancer Research Center Receives CIHR Grant To Investigate High-Resolution OCT Imaging of Bronchial Epithelium
      B.C. Cancer Research Center received an operating grant from the Canadian Institutes of Health Research for $84,255 (Canadian Dollars) to investigate high-resolution OCT Imaging of Bronchial Epithelium. The principal investigator is Pierre Lane. Below is a summary of that work. Lung cancer is the most common cause of cancer death world-wide. More than 1.3 million people die annually and the 5-year survival rates have improved only marginally ...
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    9. Ovna Medical Inc. Signs Patent License Agreement with The University of Texas at Austin to Develop Technologies Used for Disease Detection and Monitoring

      Ovna Medical Inc. Signs Patent License Agreement with The University of Texas at Austin to Develop Technologies Used for Disease Detection and Monitoring
      ...n the opportunity to have further refined devices tested in a 150 patient trial that will be conducted at the British Columbia Cancer Agency. The clinical assessment studies should be completed in 2012 and will provide c...
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    10. Quantitative Assessment of the Airway Wall Using Computed Tomography and Optical Coherence Tomography

      Ever since the site and nature of airflow obstruction in chronic obstructive pulmonary disease was described by Hogg, Thurlbeck, and Macklem, investigators have been looking for methods to noninvasively measure the airway wall dimensions. Recent advances in computed tomography technology and new computer algorithms have made it possible to visualize and measure the airway wall and lumen without the need for tissue. However, while there is great hope for computed ...
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    11. 16-30 of 36 « 1 2 3 »
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  2. About British Columbia Cancer Agency

    British Columbia Cancer Agency

    The BC Cancer Research Centre (BCCRC) is located in Vancouver, British Columbia, Canada. Scientists and researchers perform basic, epidemiologic, and clinical research on cancer prevention, early diagnosis of cancer, the molecular and genetic characteristics of the cancer process, and basic research related to new treatments for cancer. With direct links to the cancer centres across the province, discoveries at the BCCRC are quickly translated into clinical applications.