Articles that mention Brian J. F. Wong -Optical Coherence Tomography News

Brian J. F. Wong

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2. In vivo imaging of the internal nasal valve during different conditions using optical coherence tomography
  
  Explore Wiley Online Library Oct 22 2017 Otolaryngology
  
  Objective Previously, we proposed long-range optical coherence tomography (LR-OCT) to be an effective method for the quantitative evaluation of the nasal valve geometry. Here, the objective was to quantify the reduction in the internal nasal valve angle and cross-sectional area that results in subjective nasal airway obstruction and to evaluate the dynamic behavior of the valve during respiration using LR-OCT. Methods For 16 healthy individuals, LR-OCT was performed in each ...
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  Mentions: Zhongping Chen UC Irvine Brian J. F. Wong
3. Feature Of The Week 10/22/2017: Visualization and Detection of Ciliary Beating Pattern and Frequency in the Upper Airway using Phase Resolved Doppler Optical Coherence Tomography
  
  Explore Optical Coherence Tomography News Oct 22 2017
  
  Ciliary motion plays a critical role in the overall respiratory health of the upper airway. These cilia beat at a native frequency and in a synchronized pattern to continuously transport foreign particulate trapped in a layer of mucous out of the upper airway. Disruption of ciliary motion can lead to severe respiratory diseases and compromised respiratory function. Currently, the study of cilia requires expensive high speed cameras and high powered ...
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  Mentions: Zhongping Chen UC Irvine Brian J. F. Wong
4. Visualization and Detection of Ciliary Beating Pattern and Frequency in the Upper Airway using Phase Resolved Doppler Optical Coherence Tomography
  
  Explore Nature Publishing Group Sep 2 2017 Pulmonology
  
  Ciliary motion plays a critical role in the overall respiratory health of the upper airway. These cilia beat at a native frequency and in a synchronized pattern to continuously transport foreign particulate trapped in a layer of mucous out of the upper airway. Disruption of ciliary motion can lead to severe respiratory diseases and compromised respiratory function. Currently, the study of cilia requires expensive high speed cameras and high powered ...
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  Mentions: Zhongping Chen UC Irvine Brian J. F. Wong
5. Association of Electrochemical Therapy With Optical, Mechanical, and Acoustic Impedance Properties of Porcine Skin
  
  Explore The JAMA Network Jun 22 2017 Dermatology
  
  Importance The classic management of burn scars and other injuries to the skin has largely relied on soft-tissue transfer to resurface damaged tissue with local tissue transfer or skin graft placement. In situ generation of electrochemical reactions using needle electrodes and an application of current may be a new approach to treat scars and skin. Objective To examine the changes in optical, mechanical, and acoustic impedance properties in porcine skin ...
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  Mentions: Zhongping Chen UC Irvine Brian J. F. Wong
6. Anatomically correct visualization of the human upper airway using a high-speed long range optical coherence tomography system with an integrated positioning sensor
  
  Explore Nature Publishing Group Dec 20 2016 Pulmonology
  
  The upper airway is a complex tissue structure that is prone to collapse. Current methods for studying airway obstruction are inadequate in safety, cost, or availability, such as CT or MRI, or only provide localized qualitative information such as flexible endoscopy. Long range optical coherence tomography (OCT) has been used to visualize the human airway in vivo , however the limited imaging range has prevented full delineation of the various shapes ...
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  Mentions: Zhongping Chen UC Irvine Brian J. F. Wong
7. Biomedical Optics in Otorhinolaryngology (Textbook)
  
  Explore Springer US Sep 1 2016 Otolaryngology , Textbooks
  
  Biomedical Optics in Otorhinolaryngology: Head and Neck Surgery gives an overview of current technology in biomedical optics relevant to the field of Otorhinolaryngology and head and neck surgery. It provides a comprehensive source of knowledge for researchers and active clinicians seeking information on the principles and practical use of novel diagnostic and therapeutic technology. While most books focus exclusively on laser surgery, which has been largely unchanged for the past ...
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  Mentions: UC Irvine RWTH Aachen University Brian J. F. Wong
8. Diagnosis of subglottic stenosis in a rabbit model using long-range optical coherence tomography
  
  Explore Wiley Online Library Aug 25 2016 Otolaryngology
  
  Objectives/Hypothesis Current imaging modalities lack the necessary resolution to diagnose subglottic stenosis. The aim of this study was to use optical coherence tomography (OCT) to evaluate nascent subglottic mucosal injury and characterize mucosal thickness and structural changes using texture analysis in a simulated intubation rabbit model. Study Design Prospective animal study in rabbits. Methods Three-centimeter-long sections of endotracheal tubes (ETT) were endoscopically placed in the subglottis and proximal trachea ...
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  Mentions: Zhongping Chen UC Irvine Brian J. F. Wong
9. Quantitative Evaluation of Adult Subglottic Stenosis Using Intraoperative Long-range Optical Coherence Tomography
  
  Explore aor.sagepub.com Jun 27 2016 Otolaryngology
  
  Objectives: To determine the feasibility of long-range optical coherence tomography (LR-OCT) as a tool to intraoperatively image and measure the subglottis and trachea during suspension microlaryngoscopy before and after endoscopic treatment of subglottic stenosis (SGS). Methods: Long-range optical coherence tomography of the adult subglottis and trachea was performed during suspension microlaryngoscopy before and after endoscopic treatment for SGS. The anteroposterior and transverse diameters, cross-sectional area (CSA), distance from the vocal ...
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  Mentions: Zhongping Chen UC Irvine Brian J. F. Wong
10. Measurement of ciliary beat frequency using ultra-high resolution optical coherence tomography
  
  Explore Conference Proceedings Mar 22 2016
  
  Ciliated epithelial cells populate up to 80% of the surface area of the human airway and are responsible for mucociliary transport, which is the key protective mechanism that provides the first line of defense in the respiratory tract. Cilia beat in a rhythmic pattern and may be easily affected by allergens, pollutants, and pathogens, altering ciliary beat frequency (CBF) subsequently. Diseases including cystic fibrosis, chronic obstructive pulmonary disease, and primary ...
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  Mentions: Zhongping Chen UC Irvine Brian J. F. Wong
11. In vivo cross-sectional imaging of the phonating larynx using long-range Doppler optical coherence tomography
  
  Explore Nature Publishing Group Mar 11 2016 Otolaryngology
  
  Diagnosis and treatment of vocal fold lesions has been a long-evolving science for the otolaryngologist. Contemporary practice requires biopsy of a glottal lesion in the operating room under general anesthesia for diagnosis. Current in-office technology is limited to visualizing the surface of the vocal folds with fiber-optic or rigid endoscopy and using stroboscopic or high-speed video to infer information about submucosal processes. Previous efforts using optical coherence tomography (OCT) have ...
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  Mentions: Zhongping Chen UC Irvine Brian J. F. Wong
12. Long-Range Optical Coherence Tomography of the Neonatal Upper Airway for Early Diagnosis of Intubation-related Subglottic Injury
  
  Explore Home (thoracic) Dec 16 2015 Pulmonology
  
  Rationale: Subglottic edema and acquired subglottic stenosis are potentially airway-compromising sequelae in neonates following endotracheal intubation. At present, no imaging modality is capable of in vivo diagnosis of subepithelial airway wall pathology as signs of intubation-related injury. Objectives: To use Fourier domain long-range optical coherence tomography (LR-OCT) to acquire micrometer-resolution images of the airway wall of intubated neonates in a neonatal intensive care unit setting and to analyze images for ...
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  Mentions: Zhongping Chen UC Irvine Brian J. F. Wong
13. Imaging of the internal nasal valve using long-range Fourier domain optical coherence tomography
  
  Explore Wiley Online Library Nov 24 2015 Otolaryngology
  
  Objectives/Hypothesis To evaluate for the first time the feasibility and methodology of long-range Fourier domain optical coherence tomography (LR-OCT) imaging of the internal nasal valve (INV) area in healthy individuals. Study Design Prospective individual cohort study. Methods For 16 individuals, OCT was performed in each nare. The angle and the cross-sectional area of the INV were measured. OCT images were compared to corresponding digital pictures recorded with a flexible ...
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  Mentions: Zhongping Chen UC Irvine Brian J. F. Wong
14. Spatiotemporal correlation of optical coherence tomography in-vivo images of rabbit airway for the diagnosis of edema
  
  Explore SPIE | Journal Jul 30 2015 Pulmonology
  
  Detection of an early stage of subglottic edema is vital for airway management and prevention of stenosis, a life-threatening condition in critically ill neonates. As an observer for the task of diagnosing edema in vivo , we investigated spatiotemporal correlation (STC) of full-range optical coherence tomography (OCT) images acquired in the rabbit airway with experimentally simulated edema. Operating the STC observer on OCT images generates STC coefficients as test statistics for ...
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15. Long Range Optical Coherence Tomography of the Neonatal Upper Airway for Early Diagnosis of Intubation-related Subglottic Injury
  
  Explore Home (thoracic) Jul 28 2015 Pulmonology
  
  Subglottic edema and acquired subglottic stenosis are potentially airway -compromising sequelae in neonates following endotracheal intubation . At present, no imaging modality is capable of in vivo diagnosis of subepithelial airway wall pathology as signs of intubation - related injury . OBJECTIVES: To use Fourier domain long - range optical coherence tomography (LR-OCT) to acquire micrometer-resolution images of the airway wall of intubated neonates in a neonatal intensive care unit (NICU) setting and to ...
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  Mentions: Zhongping Chen UC Irvine Brian J. F. Wong
16. Measurement of ciliary beat frequency using Doppler optical coherence tomography
  
  Explore Wiley Online Library Jul 4 2015
  
  Background Measuring ciliary beat frequency (CBF) is a technical challenge and difficult to perform in vivo. Doppler optical coherence tomography (D-OCT) is a mesoscopic noncontact imaging modality that provides high-resolution tomographic images and detects micromotion simultaneously in living tissues. In this work we used D-OCT to measure CBF in ex vivo tissue as the first step toward translating this technology to clinical use. Methods Fresh ex vivo samples of rabbit ...
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  Mentions: Zhongping Chen UC Irvine Brian J. F. Wong
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